Larissa M. Podust

5.3k citations

76 papers · 4.2k indexed · h-index 42

Co-authors: David H. Sherman Michael R. Waterman T.L. Poulos Paul R. Ortiz de Montellano Vladimir N. Podust Hugues Ouellet James H. McKerrow Shengying Li
Topics: Pharmacogenetics and Drug Metabolism (36 papers)Microbial Natural Products and Biosynthesis (18 papers)Trypanosoma species research and implications (17 papers)
Cited by: Pharmacology Organic Chemistry
Journals: Chemical Reviews Proceedings of the National Academy of Sciences Journal of the American Chemical Society
Partner nations: United States Brazil United Kingdom

In The Last Decade

Larissa M. Podust

76 papers receiving 4.2k citations

Peers

Countries citing papers authored by Larissa M. Podust

Since Specialization

Citations

This map shows the geographic impact of Larissa M. Podust's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Larissa M. Podust with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Larissa M. Podust more than expected).

Fields of papers citing papers by Larissa M. Podust

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Larissa M. Podust. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Larissa M. Podust. The network helps show where Larissa M. Podust may publish in the future.

Co-authorship network of co-authors of Larissa M. Podust

This figure shows the co-authorship network connecting the top 25 collaborators of Larissa M. Podust. A scholar is included among the top collaborators of Larissa M. Podust based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Larissa M. Podust. Larissa M. Podust is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors 2023 ·Journal of Medicinal Chemistry ·Vandna Sharma,Valentina Noemi Madia,Valeria Tudino,(unknown),Anjan Debnath,Antonella Messore,(unknown),(unknown),(unknown),(unknown),Luisa Seguella,Giuseppe Esposito,Rita Petrucci,Paola Di Matteo,Martina Bortolami,Francesco Saccoliti,Roberto Di Santo,Luigi Scipione,Roberta Costi,Larissa M. Podust	8
2	Homodimerization Counteracts the Detrimental Effect of Nitrogenous Heme Ligands on the Enzymatic Activity of Acanthamoeba castellanii CYP51 2022 ·Biochemistry ·Karin Nienhaus,Vandna Sharma,G. Ulrich Nienhaus,Larissa M. Podust	3
3	Domain-Swap Dimerization of Acanthamoeba castellanii CYP51 and a Unique Mechanism of Inactivation by Isavuconazole 2020 ·Molecular Pharmacology ·Vandna Sharma,(unknown),(unknown),Anjan Debnath,Larissa M. Podust	7
4	Exploring the molecular basis for substrate specificity in homologous macrolide biosynthetic cytochromes P450 2019 ·Journal of Biological Chemistry ·Matthew D. DeMars,(unknown),Song Yang,Marc Garcia‐Borràs,Jacob N. Sanders,K. N. Houk,Larissa M. Podust,David H. Sherman	7
5	Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri 2018 ·PLoS Pathogens ·Wenxu Zhou,Anjan Debnath,(unknown),(unknown),(unknown),Minu Chaudhuri,W. David Nes,Larissa M. Podust	35
6	4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection 2017 ·PLoS neglected tropical diseases ·Cláudia M. Calvet,(unknown),Diane Thomas,Brian M. Suzuki,Ken Hirata,(unknown),(unknown),(unknown),Marcelo Meuser-Batista,(unknown),Jair L. Siqueira-Neto,William Roush,Mirian Cláudia de Souza Pereira,James H. McKerrow,Larissa M. Podust	25
7	CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM) 2017 ·PLoS neglected tropical diseases ·Anjan Debnath,Cláudia M. Calvet,(unknown),Wenxu Zhou,Alexander A. Aksenov,Madeline R. Luth,Ruben Abagyan,W. David Nes,James H. McKerrow,Larissa M. Podust	47
8	Enzymatic hydroxylation of an unactivated methylene C–H bond guided by molecular dynamics simulations 2015 ·Nature Chemistry ·Alison R. H. Narayan,Gonzalo Jiménez‐Osés,Peng Liu,Solymar Negretti,Wanxiang Zhao,Michael M. Gilbert,Raghunath O. Ramabhadran,(unknown),(unknown),Zhe Li,Larissa M. Podust,John Montgomery,K. N. Houk,David H. Sherman	107
9	R-Configuration of 4-Aminopyridyl-Based Inhibitors of CYP51 Confers Superior Efficacy Against Trypanosoma cruzi 2014 ·ACS Medicinal Chemistry Letters ·Jun Yong Choi,Cláudia M. Calvet,Débora Vieira,Shamila S. Gunatilleke,Michael D. Cameron,James H. McKerrow,Larissa M. Podust,William Roush	15
10	Chemical–biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target 2013 ·Beilstein Journal of Organic Chemistry ·(unknown),Clifford Bryant,Cláudia M. Calvet,Patricia S. Doyle,Shamila S. Gunatilleke,Siegfried S. F. Leung,Kenny K. H. Ang,Steven Chen,Jiří Gut,Juan A. Osés-Prieto,Jonathan B. Johnston,Michelle R. Arkin,Alma L. Burlingame,Jack Taunton,Matthew P. Jacobson,(unknown),Larissa M. Podust,Adam R. Renslo	31
11	Substrate Recognition by the Multifunctional Cytochrome P450 MycG in Mycinamicin Hydroxylation and Epoxidation Reactions 2012 ·Journal of Biological Chemistry ·Shengying Li,(unknown),Florentine U. Rutaganira,P.M. Kells,Yojiro Anzai,Fumio Kato,Thomas C. Pochapsky,David H. Sherman,Larissa M. Podust	58
12	Tirandamycin biosynthesis is mediated by co-dependent oxidative enzymes 2011 ·Nature Chemistry ·(unknown),Shengying Li,Shamila S. Gunatilleke,Yojiro Anzai,(unknown),Larissa M. Podust,David H. Sherman	78
13	Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1 2010 ·Bioorganic & Medicinal Chemistry Letters ·Hugues Ouellet,P.M. Kells,Paul R. Ortiz de Montellano,Larissa M. Podust	25
14	X-ray Structure of 4,4′-Dihydroxybenzophenone Mimicking Sterol Substrate in the Active Site of Sterol 14α-Demethylase (CYP51) 2008 ·Journal of Biological Chemistry ·Ali Nasser Eddine,Jens Peter von Kries,(unknown),Thulasi Warrier,Stefan H. E. Kaufmann,Larissa M. Podust	33
15	A Second FMN Binding Site in Yeast NADPH-Cytochrome P450 Reductase Suggests a Mechanism of Electron Transfer by Diflavin Reductases 2006 ·Structure ·David C. Lamb,Youngchang Kim,Liudmila V. Yermalitskaya,(unknown),Galina I. Lepesheva,Steven L. Kelly,Michael R. Waterman,Larissa M. Podust	47
16	Estriol Bound and Ligand-free Structures of Sterol 14α-Demethylase 2004 ·Structure ·Larissa M. Podust,Liudmila V. Yermalitskaya,Galina I. Lepesheva,Vladimir N. Podust,Enrique A. Dalmasso,Michael R. Waterman	71
17	Identification of Amino Acids in Rat Pregnane X Receptor that Determine Species-Specific Activation 2004 ·Molecular Pharmacology ·Rommel G. Tirona,Brenda F. Leake,Larissa M. Podust,Richard B. Kim	59
18	The Cytochrome P450 Complement (CYPome) of Streptomyces coelicolor A3(2) 2002 ·Journal of Biological Chemistry ·David C. Lamb,(unknown),(unknown),Colin J. Jackson,Larissa M. Podust,Michael R. Waterman,Douglas B. Kell,Diane Kelly,Steven L. Kelly	112
19	Crystal Structure of the CCAAT Box/Enhancer-binding Protein β Activating Transcription Factor-4 Basic Leucine Zipper Heterodimer in the Absence of DNA 2001 ·Journal of Biological Chemistry ·Larissa M. Podust,Andrzej M. Krezel,Youngchang Kim	76
20	Assembly of DNA polymerase 6 and e holoenzymes depends on the geometry of the DNA template 1994 ·Nucleic Acids Research ·Larissa M. Podust,Vladimir N. Podust,(unknown),Ulrich Hübscher	46

About Larissa M. Podust

Larissa M. Podust is a scholar working on Pharmacology, Pharmacology and Endocrinology, having authored 76 papers that have together received 4.2k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (36 papers), Microbial Natural Products and Biosynthesis (18 papers) and Trypanosoma species research and implications (17 papers). The work is most often cited by research in Pharmacology (1.4k citations), Pharmacology (886 citations) and Organic Chemistry (958 citations). Larissa M. Podust has collaborated with scholars based in United States, Brazil and United Kingdom. Frequent co-authors include David H. Sherman, Michael R. Waterman, T.L. Poulos, Paul R. Ortiz de Montellano, Vladimir N. Podust, Hugues Ouellet, James H. McKerrow, Shengying Li, Jonathan B. Johnston and P.M. Kells. Their work appears in journals such as Chemical Reviews, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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