K. N. Houk

118.9k citations

1.7k papers · 98.4k indexed · 34 hit papers · h-index 143

Impact in

Organic Chemistry top 0.01%
- Asymmetric Synthesis and Catalysis
- Catalytic C–H Functionalization Methods
- Organic Chemistry Cycloaddition Reactions
- Cyclopropane Reaction Mechanisms
- Synthetic Organic Chemistry Methods
Physical and Theoretical Chemistry top 0.01%

Papers in

Organic Chemistry 1.3k
- Organic Chemistry Cycloaddition Reactions 299
- Asymmetric Synthesis and Catalysis 292
- Catalytic C–H Functionalization Methods 197
- Cyclopropane Reaction Mechanisms 166
- Chemical Reaction Mechanisms 149
- Synthetic Organic Chemistry Methods 127
Physical and Theoretical Chemistry 231

Co-authors: Daniel H. Ess Steven E. Wheeler Nelson G. Rondan Peng Liu F. Matthias Bickelhaupt Paul Ha‐Yeon Cheong Yong Liang Sogole Bahmanyar
Journals: Journal of the American Chemical Society (594 papers)The Journal of Organic Chemistry (224 papers)Angewandte Chemie International Edition (82 papers)Organic Letters (70 papers)Tetrahedron Letters (57 papers)
Partner nations: United States China Germany

In The Last Decade

K. N. Houk

1.6k papers receiving 96.1k citations

Hit Papers

15 papers align trajectories log scale

Double Strain-Release [2π+2σ]-Photocycloaddition 2024 · 75 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2024 Journal of the American Chemical Society
2024 Journal of the American Chemical Society
2023 Science
2023 Nature
2023 Journal of the American Chemical Society
2022 Science
2021 Science
2019 Science
2017 Angewandte Chemie International Edition
2015 Nature
2013 Angewandte Chemie International Edition
2012 Journal of the American Chemical Society
2011 Chemical Reviews
2010 Science
2009 Journal of the American Chemical Society
2008 Journal of the American Chemical Society
2008 Journal of the American Chemical Society
2008 Science
2008 Nature
2007 Journal of the American Chemical Society
2004 Accounts of Chemical Research
2004 Journal of the American Chemical Society
2004 Journal of Chemical Theory and Computation
2003 Journal of the American Chemical Society
2002 Journal of the American Chemical Society
1995 Accounts of Chemical Research
1992 Angewandte Chemie International Edition in English
1990 Journal of the American Chemical Society
1988 Chemical Physics Letters
1987 The Journal of Organic Chemistry
1986 Organometallics
1975 Accounts of Chemical Research
1973 Journal of the American Chemical Society
1973 Journal of the American Chemical Society

Peers

Countries citing papers authored by K. N. Houk

Since Specialization

Citations

This map shows the geographic impact of K. N. Houk's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by K. N. Houk with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites K. N. Houk more than expected).

Fields of papers citing papers by K. N. Houk

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by K. N. Houk. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by K. N. Houk. The network helps show where K. N. Houk may publish in the future.

Co-authors

The 25 scholars most cited alongside K. N. Houk, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with K. N. Houk Line = papers co-authored together K. N. Houk links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Iminium catalysis in natural Diels–Alderase Nature Catalysis ·Zuodong Sun, Xin Zang, Qingyang Zhou, Masao Ōhashi, K. N. Houk, Jiahai Zhou, Yi Tang	2025	4
2	Molecular Dynamics of Cope Rearrangements of Substituted 1,5-Hexadienes: Variable Transition States and Mechanisms The Journal of Organic Chemistry ·Zhixin Qin, Qingyang Zhou, Joel L. Mackey, Rong-Kai Wu, Xin Hong, K. N. Houk	2025	0
3	Gas-Phase-like Inertial Rotation of a Platonic Solid in Reticular Amphidynamic Crystals of CUB-5: Molecular Dynamics and Experiment Journal of the American Chemical Society ·Jing‐Ran Shan, Qingyang Zhou, R. Yamamoto, S. Saib, Roberto Chávez, S. E. Brown, K. N. Houk, Miguel A. Garcı́a-Garibay	2025	0
4	Total Synthesis of Lissodendoric Acid A Angewandte Chemie International Edition ·Francesca M. Ippoliti, Laura G. Wonilowicz, Nathan J. Adamson, Evan R. Darzi, Joyann S. Donaldson, Daniel J. Nasrallah, Milauni M. Mehta, Andrew V. Kelleghan, K. N. Houk, Neil K. Garg	2024	5
5	Iridium nitrenoid-enabled arene C−H functionalization Nature Catalysis ·Liangwen Qi, Torben Rogge, K. N. Houk, Yixin Lü	2024	11
6	Low-Temperature Mineralization of Fluorotelomers with Diverse Polar Head Groups Journal of the American Chemical Society ·Richard J. Monsky, Yuli Li, K. N. Houk, William R. Dichtel	2024	15
7	Iron Heme Enzyme-Catalyzed Cyclopropanations with Diazirines as Carbene Precursors: Computational Explorations of Diazirine Activation and Cyclopropanation Mechanism Journal of the American Chemical Society ·Torben Rogge, Qingyang Zhou, Nicholas J. Porter, Frances H. Arnold, K. N. Houk	2024	20
8	Chemiexcitation Acceleration of 1,2‐Dioxetanes by Spiro‐Fused Six‐Member Rings with Electron‐Withdrawing Motifs Angewandte Chemie International Edition ·Maya David, Thomas Leirikh, Omri Shelef, Sara Gutkin, Tal Kopp, Qingyang Zhou, Pengchen Ma, Micha Fridman, K. N. Houk, Doron Shabat	2024	15
9	Enzymatic Benzofuranoindoline Formation in the Biosynthesis of the Strained Bridgehead Bicyclic Dipeptide (+)‐Azonazine A Angewandte Chemie International Edition ·Mengting Liu, Masao Ōhashi, Qingyang Zhou, Jacob N. Sanders, Erin P. McCauley, Phillip Crews, K. N. Houk, Yi Tang	2023	5
10	Low-temperature mineralization of perfluorocarboxylic acids Science ·Brittany Trang, Yuli Li, Xiao‐Song Xue, Mohamed Ateia, K. N. Houk, William R. Dichtel Hit paper breakdown →	2022	258
11	Isolation and X-ray Crystal Structure of an Electrogenerated TEMPO–N ₃ Charge-Transfer Complex Organic Letters ·Hosea M. Nelson, Juno C. Siu, Ambarneil Saha, Duilio Cascio, Samantha N. MacMillan, Song-Bai Wu, Chenxi Lu, José A. Rodríguez, K. N. Houk, Song Lin	2021	14
12	Pd(II)-Catalyzed Synthesis of Benzocyclobutenes by β-Methylene-Selective C(sp ³ )–H Arylation with a Transient Directing Group Journal of the American Chemical Society ·Philip Provencher, John Hoskin, Jonathan J. Wong, Xiangyang Chen, Jin‐Quan Yu, K. N. Houk, Erik J. Sorensen	2021	51
13	Nonenzymatic Stereoselective S -Glycosylation of Polypeptides and Proteins Journal of the American Chemical Society ·Liqiang Wan, Xia Zhang, Yike Zou, Rong Shi, Jin-Ge Cao, Shiyang Xu, Li‐Fan Deng, Li Zhou, Yanqiu Gong, Xiaoling Shu, Ga Young Lee, Haiyan Ren, Lunzhi Dai, Shiqian Qi, K. N. Houk, Dawen Niu	2021	92
14	Total Synthesis and Computational Investigations of Sesquiterpene-Tropolones Ameliorate Stereochemical Inconsistencies and Resolve an Ambiguous Biosynthetic Relationship Journal of the American Chemical Society ·Christopher Y. Bemis, Chad N. Ungarean, Alexander S. Shved, Cooper S. Jamieson, Taehwan Hwang, Ken S. Lee, K. N. Houk, David Šarlah	2021	37
15	Cross-metathesis of Allenes. Mechanistic Analysis and Identification of a Ru-CAAC as the Most Effective Catalyst Journal of the American Chemical Society ·Stella A. Gonsales, Zoé C. Mueller, Fengyue Zhao, Paulo H. S. Paioti, Lydia Karmazin, Jing Wan, Fang Liu, K. N. Houk, Amir H. Hoveyda	2021	15
16	Enabling microbial syringol conversion through structure-guided protein engineering Proceedings of the National Academy of Sciences ·Melodie M. Machovina, S.J.B. Mallinson, Brandon C. Knott, Alexander Meyers, Marc Garcia‐Borràs, Lintao Bu, Japheth E. Gado, April Oliver, Graham P. Schmidt, D.J. Hinchen, Michael F. Crowley, Christopher W. Johnson, Ellen L. Neidle, Christina M. Payne, K. N. Houk, Gregg T. Beckham, J.E. McGeehan, Jennifer L. DuBois	2019	52
17	Origins of halogen effects in bioorthogonal sydnone cycloadditions Chemical Communications ·Huimin Tao, Fang Liu, Ruxin Zeng, Zhuzhou Shao, Lufeng Zou, Cao Yang, Jennifer M. Murphy, K. N. Houk, Yong Liang	2018	28
18	Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59 Proceedings of the National Academy of Sciences ·Olga Khersonsky, Gert Kiss, Daniela Röthlisberger, Orly Dym, Shira Albeck, K. N. Houk, David Baker, Dan S. Tawfik	2012	189
19	Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction Science ·Justin B. Siegel, Alexandre Zanghellini, Helena M. Lovick, Gert Kiss, Abigail R. Lambert, Jennifer L. St.Clair, Jasmine L. Gallaher, Donald Hilvert, Michael H. Gelb, Barry Stoddard, K. N. Houk, Forrest E. Michael, David Baker Hit paper breakdown →	2010	692
20	Thionitroxides, RSNHO ^• : The Structure of the SNO Moiety in “ S -Nitrosohemoglobin”, A Possible NO Reservoir and Transporter Journal of the American Chemical Society ·Yi‐Lei Zhao, K. N. Houk	2006	27

About K. N. Houk

K. N. Houk is a scholar working on Organic Chemistry, Physical and Theoretical Chemistry, Pharmaceutical Science, Inorganic Chemistry and Spectroscopy, having authored 1.7k papers that have together received 98.4k indexed citations. Recurring topics across this work include Organic Chemistry Cycloaddition Reactions (299 papers), Asymmetric Synthesis and Catalysis (292 papers), Catalytic C–H Functionalization Methods (197 papers), Advanced Chemical Physics Studies (181 papers), Cyclopropane Reaction Mechanisms (166 papers), Chemical Synthesis and Analysis (149 papers), Chemical Reaction Mechanisms (149 papers) and Synthetic Organic Chemistry Methods (127 papers). The work is most often cited by research in Organic Chemistry (68.7k citations), Physical and Theoretical Chemistry (9.2k citations), Inorganic Chemistry (13.6k citations), Pharmaceutical Science (5.0k citations) and Process Chemistry and Technology (1.5k citations). K. N. Houk has collaborated with scholars based in United States, China and Germany. Frequent co-authors include Daniel H. Ess, Steven E. Wheeler, Nelson G. Rondan, Peng Liu, F. Matthias Bickelhaupt, Paul Ha‐Yeon Cheong, Yong Liang, Sogole Bahmanyar, Yu Takano and Yun Wu. Their work appears in journals such as Journal of the American Chemical Society, The Journal of Organic Chemistry, Angewandte Chemie International Edition, Organic Letters and Tetrahedron Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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