John Wai

5.0k total citations · 1 hit paper
30 papers, 1.7k citations indexed

About

John Wai is a scholar working on Organic Chemistry, Molecular Biology and Infectious Diseases. According to data from OpenAlex, John Wai has authored 30 papers receiving a total of 1.7k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Organic Chemistry, 14 papers in Molecular Biology and 11 papers in Infectious Diseases. Recurrent topics in John Wai's work include HIV/AIDS drug development and treatment (11 papers), HIV Research and Treatment (8 papers) and Biochemical and Molecular Research (7 papers). John Wai is often cited by papers focused on HIV/AIDS drug development and treatment (11 papers), HIV Research and Treatment (8 papers) and Biochemical and Molecular Research (7 papers). John Wai collaborates with scholars based in United States, China and Hong Kong. John Wai's co-authors include J. M. HOFFMAN, Thorsten E. Fisher, Daria J. Hazuda, Walfred S. Saari, Abigail Wolfe, Marc Witmer, Mark E. Goldman, William A. Schleif, Joseph P. Vacca and K. Barry Sharpless and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

John Wai

29 papers receiving 1.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A mechanistic insight leads to a greatly improved osmium-catalyzed asymmetric dihydroxylation process

1989 180 citations John Wai et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
John Wai United States	17	936	828	768	649	184	30	1.7k
Norman E. Wideburg United States	13	888 0.9×	603 0.7×	710 0.9×	613 0.9×	149 0.8×	29	1.5k
Ronald M. Klabe United States	24	629 0.7×	1.0k 1.2×	471 0.6×	685 1.1×	118 0.6×	47	1.8k
Karl Grozinger United States	14	770 0.8×	664 0.8×	619 0.8×	439 0.7×	156 0.8×	34	1.4k
Melissa S. Egbertson United States	20	664 0.7×	535 0.6×	564 0.7×	771 1.2×	115 0.6×	35	1.8k
Raveendra Dayam United States	23	674 0.7×	991 1.2×	547 0.7×	707 1.1×	93 0.5×	43	1.8k
Marlene M. Rayner United States	14	597 0.6×	527 0.6×	533 0.7×	590 0.9×	100 0.5×	19	1.3k
Tino W. Sanchez United States	26	529 0.6×	1.0k 1.2×	377 0.5×	682 1.1×	136 0.7×	48	2.0k
Christiane Yoakim Canada	28	306 0.3×	1.1k 1.3×	257 0.3×	624 1.0×	201 1.1×	51	1.8k
James P. Guare United States	14	432 0.5×	546 0.7×	369 0.5×	425 0.7×	81 0.4×	32	1.1k
Rhonda B. Levin United States	9	527 0.6×	425 0.5×	405 0.5×	428 0.7×	77 0.4×	9	1.1k

Countries citing papers authored by John Wai

Since Specialization

Citations

This map shows the geographic impact of John Wai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Wai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Wai more than expected).

Fields of papers citing papers by John Wai

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Wai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Wai. The network helps show where John Wai may publish in the future.

Co-authorship network of co-authors of John Wai

This figure shows the co-authorship network connecting the top 25 collaborators of John Wai. A scholar is included among the top collaborators of John Wai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John Wai. John Wai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Peng, Yutian, John G. Moffat, Eric M. Kofoed, et al.. (2024). Differential effects of inosine monophosphate dehydrogenase (IMPDH/GuaB) inhibition in Acinetobacter baumannii and Escherichia coli. Journal of Bacteriology. 206(10). e0010224–e0010224. 2 indexed citations

Dragovich, Peter S., Fabio Broccatelli, Jinhua Chen, et al.. (2017). Design, synthesis, and biological evaluation of pyrrolobenzodiazepine-containing hypoxia-activated prodrugs. Bioorganic & Medicinal Chemistry Letters. 27(23). 5300–5304. 9 indexed citations

Li, Wenping, Wayne J. Thompson, Thorsten E. Fisher, et al.. (2010). Radiosynthesis of the HIV integrase inhibitor [¹⁸F]MK‐0518 (Isentress). Journal of Labelled Compounds and Radiopharmaceuticals. 53(7). 517–520. 3 indexed citations

Fisher, Thorsten E., Bo-Young Kim, Terry A. Lyle, et al.. (2007). 8-Hydroxy-3,4-dihydropyrrolo[1,2-a]pyrazine-1(2H)-one HIV-1 integrase inhibitors. Bioorganic & Medicinal Chemistry Letters. 17(23). 6511–6515. 31 indexed citations

Wai, John, Bo Young Kim, Thorsten E. Fisher, et al.. (2007). Dihydroxypyridopyrazine-1,6-dione HIV-1 integrase inhibitors. Bioorganic & Medicinal Chemistry Letters. 17(20). 5595–5599. 21 indexed citations

Perlow, Debra S., et al.. (2007). Practical Synthesis of 4‐Fluoro‐2‐(methylthio)benzylamine and the Corresponding Sulfone and Sulfonamide. Synthetic Communications. 37(11). 1887–1897. 5 indexed citations

Guare, James P., John Wai, Robert Gomez, et al.. (2006). A series of 5-aminosubstituted 4-fluorobenzyl-8-hydroxy-[1,6]naphthyridine-7-carboxamide HIV-1 integrase inhibitors. Bioorganic & Medicinal Chemistry Letters. 16(11). 2900–2904. 37 indexed citations

Zhuang, Linghang, John Wai, Mark W. Embrey, et al.. (2003). Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells. Journal of Medicinal Chemistry. 46(4). 453–456. 219 indexed citations

Shaw-Reid, Cathryn A., Vandna Munshi, Pia Graham, et al.. (2003). Inhibition of HIV-1 Ribonuclease H by a Novel Diketo Acid, 4-[5-(Benzoylamino)thien-2-yl]-2,4-dioxobutanoic Acid. Journal of Biological Chemistry. 278(5). 2777–2780. 135 indexed citations

10.

Chiba, Masato, Cuyue Tang, William Neway, et al.. (2001). P450 interaction with farnesyl-protein transferase inhibitors metabolic stability, inhibitory potency, and P450 binding spectra in human liver microsomes 1 1Abbreviations: FTI, farnesyl-protein transferase inhibitor; FTase, farnesyl-protein transferase; and LC-MS, liquid chromatography-mass spectrometry.. Biochemical Pharmacology. 62(6). 773–776. 19 indexed citations

11.

Egbertson, Melissa S., Bohumil Bednář, Ben Askew, et al.. (2000). Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors. Bioorganic & Medicinal Chemistry Letters. 10(17). 1943–1948. 2 indexed citations

12.

Wai, John, Thorsten E. Fisher, Samuel Graham, et al.. (1994). Synthesis and biological activity of ras farnesyl protein transferase inhibitors. Tetrapeptide analogs with amino methyl and carbon linkages. Bioorganic & Medicinal Chemistry. 2(9). 939–947. 23 indexed citations

13.

Piers, Edward & John Wai. (1994). Stereoselective total synthesis of the marine sesterterpenoid (±)-palauolide. Canadian Journal of Chemistry. 72(1). 146–157. 21 indexed citations

14.

Wai, John, Theresa M. Williams, Thorsten E. Fisher, et al.. (1993). Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one. Journal of Medicinal Chemistry. 36(2). 249–255. 37 indexed citations

15.

HOFFMAN, J. M., Anthony M. Smith, Clarence S. Rooney, et al.. (1993). Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 4. 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one and analogs. Journal of Medicinal Chemistry. 36(8). 953–966. 69 indexed citations

16.

Saari, Walfred S., John Wai, Thorsten E. Fisher, et al.. (1992). Synthesis and evaluation of 2-pyridinone derivatives as HIV-1-specific reverse transcriptase inhibitors. 2. Analogs of 3-aminopyridin-2(1H)-one. Journal of Medicinal Chemistry. 35(21). 3792–3802. 75 indexed citations

17.

HOFFMAN, J. M., et al.. (1992). Synthesis and evaluation of 2-pyridinone derivatives as HIV-1 specific reverse transcriptase inhibitors. 1. Phthalimidoalkyl and -alkylamino analogs. Journal of Medicinal Chemistry. 35(21). 3784–3791. 44 indexed citations

18.

Saari, Walfred S., J. M. HOFFMAN, John Wai, et al.. (1991). 2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors. Journal of Medicinal Chemistry. 34(9). 2922–2925. 101 indexed citations

19.

Piers, Edward & John Wai. (1987). Total synthesis of the sesterterpenoid (±)-palauolide. Journal of the Chemical Society Chemical Communications. 0(18). 1342–1343. 4 indexed citations

20.

Jie, Marcel S. F. Lie Ken, et al.. (1981). Fatty acids: XXIII. A rapid method for the preparation of C₁₈ furanoid fatty ester involving dry‐column chromatography. Journal of the American Oil Chemists Society. 58(6). 705–706. 13 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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