Gregory S. Ducker

5.3k total citations · 1 hit paper
29 papers, 3.2k citations indexed

About

Gregory S. Ducker is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Gregory S. Ducker has authored 29 papers receiving a total of 3.2k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 7 papers in Cancer Research and 6 papers in Oncology. Recurrent topics in Gregory S. Ducker's work include PI3K/AKT/mTOR signaling in cancer (9 papers), Epigenetics and DNA Methylation (6 papers) and Cancer, Hypoxia, and Metabolism (5 papers). Gregory S. Ducker is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (9 papers), Epigenetics and DNA Methylation (6 papers) and Cancer, Hypoxia, and Metabolism (5 papers). Gregory S. Ducker collaborates with scholars based in United States, Austria and Zimbabwe. Gregory S. Ducker's co-authors include Joshua D. Rabinowitz, Raphael J. Morscher, Kevan M. Shokat, Jonathan M. Ghergurovich, Xin Teng, Li Chen, Hsin‐Jung Li, Zemer Gitai, Yibin Kang and Mark Esposito and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and PLoS ONE.

In The Last Decade

Gregory S. Ducker

27 papers receiving 3.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

One-Carbon Metabolism in Health and Disease

2016 1.4k citations Gregory S. Ducker, Joshua D. Rabinowitz Cell Metabolism profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Gregory S. Ducker United States	17	2.1k	763	494	284	277	29	3.2k
Jonathan M. Ghergurovich United States	15	1.9k 0.9×	1.2k 1.5×	128 0.3×	602 2.1×	364 1.3×	18	3.1k
Elena R. García–Trevijano Spain	28	1.4k 0.6×	257 0.3×	571 1.2×	174 0.6×	264 1.0×	56	2.7k
Oliver D.K. Maddocks United Kingdom	27	3.5k 1.7×	2.2k 2.9×	223 0.5×	347 1.2×	775 2.8×	42	4.9k
Shigetaka Kitajima Japan	40	2.7k 1.3×	466 0.6×	298 0.6×	722 2.5×	542 2.0×	97	4.3k
Youichiro Wada Japan	31	1.6k 0.8×	704 0.9×	129 0.3×	637 2.2×	361 1.3×	80	3.2k
Hubert de Verneuil France	43	3.8k 1.8×	386 0.5×	609 1.2×	309 1.1×	274 1.0×	145	5.1k
Gary J. Litherland United Kingdom	21	1.1k 0.5×	323 0.4×	582 1.2×	149 0.5×	194 0.7×	42	2.1k
Yaoqin Gong China	40	3.5k 1.6×	951 1.2×	219 0.4×	663 2.3×	781 2.8×	146	5.2k
Oliver Stehling Germany	27	2.2k 1.0×	169 0.2×	173 0.4×	157 0.6×	169 0.6×	42	3.5k
Yue Huang China	34	2.1k 1.0×	330 0.4×	123 0.2×	256 0.9×	744 2.7×	101	3.6k

Countries citing papers authored by Gregory S. Ducker

Since Specialization

Citations

This map shows the geographic impact of Gregory S. Ducker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gregory S. Ducker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gregory S. Ducker more than expected).

Fields of papers citing papers by Gregory S. Ducker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gregory S. Ducker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gregory S. Ducker. The network helps show where Gregory S. Ducker may publish in the future.

Co-authorship network of co-authors of Gregory S. Ducker

This figure shows the co-authorship network connecting the top 25 collaborators of Gregory S. Ducker. A scholar is included among the top collaborators of Gregory S. Ducker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Gregory S. Ducker. Gregory S. Ducker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bott, Alex J., et al.. (2025). SLC7A5 is required for cancer cell growth under arginine-limited conditions. Cell Reports. 44(1). 115130–115130. 4 indexed citations

Ducker, Gregory S., et al.. (2025). Hyperlipidemia drives tumor growth in a mouse model of obesity-accelerated breast cancer growth. Cancer & Metabolism. 13(1). 39–39. 1 indexed citations

Stanley, Claire E., et al.. (2024). Phospholipid isotope tracing suggests β-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1869(6). 159514–159514. 2 indexed citations

Cluntun, Ahmad A., Thirupura S. Shankar, Ling Jing, et al.. (2024). Enhancing mitochondrial pyruvate metabolism ameliorates ischemic reperfusion injury in the heart. JCI Insight. 9(21).

Cluntun, Ahmad A., Thirupura S. Shankar, Ling Jing, et al.. (2024). Enhancing mitochondrial pyruvate metabolism ameliorates ischemic reperfusion injury in the heart. JCI Insight. 9(17). 9 indexed citations

McBride, Matthew J., Zhaoyue Zhang, Tara TeSlaa, et al.. (2024). Glycine homeostasis requires reverse SHMT flux. Cell Metabolism. 36(1). 103–115.e4. 29 indexed citations

Li, Albert M., Gregory S. Ducker, Yang Li, et al.. (2020). Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Molecular Cancer Research. 18(4). 599–611. 58 indexed citations

Panic, Vanja, Stephanie Pearson, Trevor S. Tippetts, et al.. (2020). Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis. eLife. 9. 47 indexed citations

Ducker, Gregory S., Leah K. Billingham, Carlos A. Martínez, et al.. (2019). Serine Metabolism Supports Macrophage IL-1β Production. Cell Metabolism. 29(4). 1003–1011.e4. 251 indexed citations

10.

Chamberlain, Chester E., Michael S. German, Katherine Yang, et al.. (2018). A Patient-derived Xenograft Model of Pancreatic Neuroendocrine Tumors Identifies Sapanisertib as a Possible New Treatment for Everolimus-resistant Tumors. Molecular Cancer Therapeutics. 17(12). 2702–2709. 34 indexed citations

11.

Mues, Marsilius, Anica M. Wandler, Milou Tenhagen, et al.. (2018). Comprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy. PLoS ONE. 13(5). e0193849–e0193849. 13 indexed citations

12.

Rodan, Lance H., Gregory S. Ducker, Didem Demirbas, et al.. (2018). 5,10-methenyltetrahydrofolate synthetase deficiency causes a neurometabolic disorder associated with microcephaly, epilepsy, and cerebral hypomyelination. Molecular Genetics and Metabolism. 125(1-2). 118–126. 14 indexed citations

13.

Morscher, Raphael J., Gregory S. Ducker, Hsin‐Jung Li, et al.. (2018). Mitochondrial translation requires folate-dependent tRNA methylation. Nature. 554(7690). 128–132. 190 indexed citations

14.

Chen, Li, Gregory S. Ducker, Wenyun Lu, Xin Teng, & Joshua D. Rabinowitz. (2017). An LC-MS chemical derivatization method for the measurement of five different one-carbon states of cellular tetrahydrofolate. Analytical and Bioanalytical Chemistry. 409(25). 5955–5964. 36 indexed citations

15.

Ducker, Gregory S., Li Chen, Raphael J. Morscher, et al.. (2016). Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metabolism. 23(6). 1140–1153. 323 indexed citations

16.

Pourdehnad, Michael, Morgan Truitt, Imran Siddiqi, et al.. (2013). Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers. Proceedings of the National Academy of Sciences. 110(29). 11988–11993. 204 indexed citations

17.

Ducker, Gregory S., Chloé E. Atreya, Jeff Simko, et al.. (2013). Incomplete inhibition of phosphorylation of 4E-BP1 as a mechanism of primary resistance to ATP-competitive mTOR inhibitors. Oncogene. 33(12). 1590–1600. 75 indexed citations

18.

Atreya, Chloé E., Gregory S. Ducker, Morris E. Feldman, et al.. (2012). Combination of ATP-competitive mammalian target of rapamycin inhibitors with standard chemotherapy for colorectal cancer. Investigational New Drugs. 30(6). 2219–2225. 15 indexed citations

19.

Ducker, Gregory S., et al.. (2011). The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile. Proceedings of the National Academy of Sciences. 108(37). 15201–15206. 90 indexed citations

20.

Okuzumi, Tatsuya, et al.. (2010). Synthesis and evaluation of indazole based analog sensitive Akt inhibitors. Molecular BioSystems. 6(8). 1389–1402. 15 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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