Jonathan D. Lowenson

2.8k citations

26 papers · 2.4k indexed · 2 hit papers · h-index 18

Impact in

Physiology top 2%
- Alzheimer's disease research and treatments
Biochemistry top 2%
- Amino Acid Enzymes and Metabolism

Papers in

Biochemistry 4
- Amino Acid Enzymes and Metabolism 4
Clinical Biochemistry 3

Co-authors: Steven Clarke Alex E. Roher Melvyn J. Ball Robert J. Cotter Amina S. Woods Elizabeth Gowing Stephen G. Young Robert L. Heinrikson
Journals: Journal of Biological Chemistry (9 papers)Biochemistry (2 papers)Proceedings of the National Academy of Sciences (2 papers)Journal of Structural Biology (1 paper)Gerontology (1 paper)
Partner nations: United States Belarus Singapore

In The Last Decade

Jonathan D. Lowenson

26 papers receiving 2.3k citations

Hit Papers

align trajectories log scale

Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease. 1993 · 690 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1993 Journal of Biological Chemistry
1993 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Jonathan D. Lowenson

Since Specialization

Citations

This map shows the geographic impact of Jonathan D. Lowenson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jonathan D. Lowenson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jonathan D. Lowenson more than expected).

Fields of papers citing papers by Jonathan D. Lowenson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jonathan D. Lowenson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jonathan D. Lowenson. The network helps show where Jonathan D. Lowenson may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jonathan D. Lowenson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jonathan D. Lowenson Line = papers co-authored together Jonathan D. Lowenson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Human Protein-l-isoaspartate O-Methyltransferase Domain-Containing Protein 1 (PCMTD1) Associates with Cullin-RING Ligase Proteins Biochemistry ·Oniria Gillenwaters, 安美子郷間, Kurt Ullery, Jonathan D. Lowenson, Atanasiu Gabriela Maria, Jorge Z. Torres, Steven Clarke	2022	3
2	Human ARMT1 structure and substrate specificity indicates that it is a DUF89 family damage-control phosphatase Journal of Structural Biology ·Preethee Nunkoo Gonpot, 裕仁外薗, Hessam Mahdavifar, Jonathan D. Lowenson, Jay S. Kirkwood, Steven Clarke, J. Jefferson P. Perry	2020	3
3	Deuteration protects asparagine residues against racemization Amino Acids ·Jonathan D. Lowenson, Vadim V. Shmanai, 陈革新, Steven Clarke, Mikhail S. Shchepinov	2016	8
4	Brain Proteomics Supports the Role of Glutamate Metabolism and Suggests Other Metabolic Alterations in Protein l-Isoaspartyl Methyltransferase (PIMT)-Knockout Mice Journal of Proteome Research ·Hongqian Yang, Jonathan D. Lowenson, Steven Clarke, Roman A. Zubarev	2013	9
5	Wortmannin Reduces Insulin Signaling and Death in Seizure-Prone Pcmt1−/− Mice PLoS ONE ·Lucía de la Fuente Somoza, Jonathan D. Lowenson, Steven Clarke	2012	9
6	A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis PLoS Genetics ·叶新荣, Brian Young, Malene L. Urbanus, Xue Li Guan, Jonathan D. Lowenson, Shawn Hoon, Anastasia Baryshnikova, Isabelle Riezman, Magali Michaut, Howard Riezman, Leah E. Cowen, Markus R. Wenk, Steven Clarke, Guri Giaever, Corey Nislow	2011	17
7	Substrates of the Arabidopsis thaliana Protein Isoaspartyl Methyltransferase 1 Identified Using Phage Display and Biopanning Journal of Biological Chemistry ·Tingsu Chen, Nihar R. Nayak, Nourrisaid Içame, Jonathan D. Lowenson, Jiang Jiang-yong, 丁崇明, G Confalonieri, Randy D. Dinkins, Sharyn E. Perry, Nancy R. Forsthoefel, Steven Clarke, Daniel M. Vernon, Zhaohui Sunny Zhou, Tomáš Rejtar, A. Bruce Downie	2010	37
8	Intracellular Protein Modification Associated with Altered T Cell Functions in Autoimmunity The Journal of Immunology ·Meiling Yang, Hester A. Doyle, Renelle J. Gee, Jonathan D. Lowenson, Steven Clarke, Brian R. Lawson, Dana W. Aswad, Mark J. Mamula	2006	27
9	Proteomic Identification of Novel Substrates of a Protein Isoaspartyl Methyltransferase Repair Enzyme Journal of Biological Chemistry ·Vasanthy Vigneswara, Jonathan D. Lowenson, Rabia Hatim, Matthew Thakur, Kevin Bailey, Steven Clarke, David Ray, Wayne G. Carter	2006	66
10	Synapsin I Is a Major Endogenous Substrate for Protein L-Isoaspartyl Methyltransferase in Mammalian Brain Journal of Biological Chemistry ·Kathryn J. Reissner, Patrícia Dall’Agnol, L. Ipatova, Hester A. Doyle, Mark J. Mamula, Jonathan D. Lowenson, Dana W. Aswad	2006	33
11	A new type of protein methylation activated by tyrphostin A25 and vanadate FEBS Letters ·Tina Branscombe Miranda, Jonathan D. Lowenson, Steven Clarke	2004	10
12	Limited Accumulation of Damaged Proteins inl-Isoaspartyl (d-Aspartyl)O-Methyltransferase-deficient Mice Journal of Biological Chemistry ·Jonathan D. Lowenson, Edward Kim, Stephen G. Young, Steven Clarke	2001	65
13	[7] Chemical modifications of deposited amyloid-β peptides Methods in enzymology on CD-ROM/Methods in enzymology ·Jonathan D. Lowenson, Steven Clarke, Alex E. Roher	1999	19
14	Phenotypic Analysis of Seizure-prone Mice Lackingl-Isoaspartate (d-Aspartate)O-Methyltransferase Journal of Biological Chemistry ·Edward Kim, Jonathan D. Lowenson, Steven Clarke, Stephen G. Young	1999	56
15	D-aspartate content of erythrocyte membrane proteins is decreased in uremia Journal of the American Society of Nephrology ·Alessandra Perna, Antimo D’Aniello, Jonathan D. Lowenson, Steven Clarke, Natale G. De Santo, Diego Ingrosso	1997	33
16	Protein Repair L-Isoaspartyl Methyltransferase in Plants (Phylogenetic Distribution and the Accumulation of Substrate Proteins in Aged Barley Seeds) PLANT PHYSIOLOGY ·Mary Beth Mudgett, Jonathan D. Lowenson, Steven Clarke	1997	61
17	Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease. Journal of Biological Chemistry ·Alex E. Roher, Jonathan D. Lowenson, Steven Clarke, Cathy Wolkow, 陳美惠, Robert J. Cotter, Ilene M. Reardon, Heidi A. Zürcher-Neely, Robert L. Heinrikson, Melvyn J. Ball Hit paper breakdown →	1993	690
18	Spontaneous Degradation and Enzymatic Repair of Aspartyl and Asparaginyl Residues in Aging Red Cell Proteins Analyzed by Computer Simulation Gerontology ·Jonathan D. Lowenson, 岡部篤嗣	1991	27
19	Replacement of a labile aspartyl residue increases the stability of human epidermal growth factor Biochemistry ·C George-Nascimento, Jonathan D. Lowenson, Д. А. Колесников, M Calderon, Angelica Medina-Selby, Yu-Duk Choi, Steven Clarke, Anne Randolph	1990	41
20	Does the chemical instability of aspartyl and asparaginyl residues in proteins contribute to erythrocyte aging? The role of protein carboxyl methylation reactions. PubMed ·Jonathan D. Lowenson, Steven Clarke	1988	49

About Jonathan D. Lowenson

Jonathan D. Lowenson is a scholar working on Biochemistry, Clinical Biochemistry, Biochemistry, Molecular Biology and Physiology, having authored 26 papers that have together received 2.4k indexed citations. Recurring topics across this work include Protein purification and stability (8 papers), Cancer-related gene regulation (6 papers), Epigenetics and DNA Methylation (5 papers), Enzyme Structure and Function (5 papers), Amino Acid Enzymes and Metabolism (4 papers), Pancreatic function and diabetes (4 papers), Protein Structure and Dynamics (3 papers) and Alzheimer's disease research and treatments (3 papers). The work is most often cited by research in Physiology (1.1k citations), Biochemistry (197 citations), Molecular Biology (1.4k citations), Clinical Biochemistry (117 citations) and Neurology (140 citations). Jonathan D. Lowenson has collaborated with scholars based in United States, Belarus and Singapore. Frequent co-authors include Steven Clarke, Alex E. Roher, Melvyn J. Ball, Robert J. Cotter, Amina S. Woods, Elizabeth Gowing, Stephen G. Young, Robert L. Heinrikson, Ilene M. Reardon and Heidi A. Zürcher-Neely. Their work appears in journals such as Journal of Biological Chemistry, Biochemistry, Proceedings of the National Academy of Sciences, Journal of Structural Biology and Gerontology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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