Alex E. Roher

20.9k total citations · 6 hit papers
136 papers, 16.6k citations indexed

About

Alex E. Roher is a scholar working on Physiology, Molecular Biology and Neurology. According to data from OpenAlex, Alex E. Roher has authored 136 papers receiving a total of 16.6k indexed citations (citations by other indexed papers that have themselves been cited), including 112 papers in Physiology, 62 papers in Molecular Biology and 29 papers in Neurology. Recurrent topics in Alex E. Roher's work include Alzheimer's disease research and treatments (112 papers), Cholinesterase and Neurodegenerative Diseases (28 papers) and Dementia and Cognitive Impairment Research (26 papers). Alex E. Roher is often cited by papers focused on Alzheimer's disease research and treatments (112 papers), Cholinesterase and Neurodegenerative Diseases (28 papers) and Dementia and Cognitive Impairment Research (26 papers). Alex E. Roher collaborates with scholars based in United States, Argentina and United Kingdom. Alex E. Roher's co-authors include Yu‐Min Kuo, Thomas G. Beach, Tyler A. Kokjohn, Mark R. Emmerling, Melvyn J. Ball, Lucia I. Sue, Robert J. Cotter, Shi Du Yan, Amina S. Woods and David M. Stern and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Alex E. Roher

136 papers receiving 16.3k citations

Hit Papers

RAGE and amyloid-β peptide neurotoxicity in Alzheimer's d... 1993 2026 2004 2015 1996 1999 1993 1993 1998 500 1000 1.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
    1996 1.7k citations Shi Du Yan, Alex E. Roher et al. profile →
  2. Soluble Amyloid β Peptide Concentration as a Predictor of Synaptic Change in Alzheimer's Disease
    1999 1.3k citations Yu‐Min Kuo, Alex E. Roher et al. American Journal Of Pathology profile →
  3. Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease.
    1993 690 citations Alex E. Roher, Steven Clarke et al. Journal of Biological Chemistry profile →
  4. beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease.
    1993 610 citations Alex E. Roher, Steven Clarke et al. profile →
  5. Cerebral Amyloid Angiopathy
    1998 529 citations Roy O. Weller, Yu‐Min Kuo et al. American Journal Of Pathology profile →
  6. Water-soluble Aβ(N-40, N-42) Oligomers in Normal and Alzheimer Disease Brains
    1996 516 citations Yu‐Min Kuo, Mark R. Emmerling et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Alex E. Roher United States 64 11.9k 6.2k 3.7k 2.3k 2.2k 136 16.6k
Jorge Ghiso United States 70 11.8k 1.0× 8.5k 1.4× 2.8k 0.8× 1.8k 0.8× 1.9k 0.9× 213 17.3k
Thomas Wısnıewskı United States 76 11.7k 1.0× 8.8k 1.4× 4.0k 1.1× 2.3k 1.0× 3.4k 1.5× 389 20.5k
Greg M. Cole United States 58 10.7k 0.9× 5.7k 0.9× 3.2k 0.9× 2.8k 1.2× 3.4k 1.5× 100 16.9k
Kelly R. Bales United States 66 12.1k 1.0× 6.1k 1.0× 3.8k 1.0× 2.8k 1.2× 3.9k 1.7× 126 17.1k
Xiongwei Zhu United States 94 14.5k 1.2× 13.5k 2.2× 3.8k 1.0× 4.2k 1.8× 4.4k 2.0× 345 28.6k
Marcia N. Gordon United States 54 14.5k 1.2× 6.9k 1.1× 6.2k 1.7× 3.2k 1.4× 4.8k 2.2× 135 20.7k
Huaxi Xu United States 75 11.9k 1.0× 8.3k 1.3× 4.7k 1.3× 2.9k 1.2× 3.5k 1.5× 195 21.4k
Lars Lannfelt Sweden 75 14.2k 1.2× 8.4k 1.4× 3.1k 0.8× 3.2k 1.4× 2.9k 1.3× 312 20.7k
Steven G. Younkin United States 56 17.1k 1.4× 8.9k 1.4× 4.3k 1.1× 4.1k 1.8× 4.8k 2.1× 103 21.6k
Dale Schenk United States 49 11.1k 0.9× 5.4k 0.9× 2.7k 0.7× 2.6k 1.1× 2.9k 1.3× 84 14.3k

Countries citing papers authored by Alex E. Roher

Since Specialization
Citations

This map shows the geographic impact of Alex E. Roher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alex E. Roher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alex E. Roher more than expected).

Fields of papers citing papers by Alex E. Roher

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alex E. Roher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alex E. Roher. The network helps show where Alex E. Roher may publish in the future.

Co-authorship network of co-authors of Alex E. Roher

This figure shows the co-authorship network connecting the top 25 collaborators of Alex E. Roher. A scholar is included among the top collaborators of Alex E. Roher based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alex E. Roher. Alex E. Roher is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Roher, Alex E., Tyler A. Kokjohn, Steven Clarke, et al.. (2017). APP/Aβ structural diversity and Alzheimer's disease pathogenesis. Neurochemistry International. 110. 1–13. 80 indexed citations
2.
Roher, Alex E., Chera L. Maarouf, Tyler A. Kokjohn, et al.. (2016). Chemical and neuropathological analyses of an Alzheimer's disease patient treated with solanezumab.. PubMed Central. 5(4). 158–170. 12 indexed citations
3.
Kokjohn, Tyler A., Chera L. Maarouf, Ian D. Daugs, et al.. (2012). Neurochemical Profile of Dementia Pugilistica. Journal of Neurotrauma. 30(11). 981–997. 29 indexed citations
4.
Kokjohn, Tyler A., Gregory D. Van Vickle, Chera L. Maarouf, et al.. (2011). Chemical characterization of pro-inflammatory amyloid-beta peptides in human atherosclerotic lesions and platelets. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1812(11). 1508–1514. 46 indexed citations
5.
Maarouf, Chera L., Ian D. Daugs, Tyler A. Kokjohn, et al.. (2011). Alzheimer's Disease and Non-Demented High Pathology Control Nonagenarians: Comparing and Contrasting the Biochemistry of Cognitively Successful Aging. PLoS ONE. 6(11). e27291–e27291. 54 indexed citations
6.
Alonso, Leonardo G., Malcolm A. Leissring, Sergio B. Kaufman, et al.. (2008). The Catalytic Domain of Insulin-degrading Enzyme Forms a Denaturant-resistant Complex with Amyloid β Peptide. Journal of Biological Chemistry. 283(25). 17039–17048. 33 indexed citations
7.
Maarouf, Chera L., Ian D. Daugs, Salvatore Spina, et al.. (2008). Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations. Molecular Neurodegeneration. 3(1). 20–20. 51 indexed citations
8.
Patton, Rebekah, Walter M. Kalback, Chera L. Esh, et al.. (2006). Amyloid-β Peptide Remnants in AN-1792-Immunized Alzheimer's Disease Patients. American Journal Of Pathology. 169(3). 1048–1063. 162 indexed citations
9.
Beach, Thomas G., Jeffrey R. Wilson, Lucia I. Sue, et al.. (2006). Circle of Willis atherosclerosis: association with Alzheimer’s disease, neuritic plaques and neurofibrillary tangles. Acta Neuropathologica. 113(1). 13–21. 191 indexed citations
10.
Chaney, Michael O., Jérôme Baudry, Chera L. Esh, et al.. (2003). Aβ, aging, and Alzheimer's disease: A tale, models, and hypotheses. Neurological Research. 25(6). 581–589. 20 indexed citations
11.
Walker, Lary C., Michael J. Callahan, Feng Bian, et al.. (2002). Exogenous induction of cerebral β-amyloidosis in βAPP-transgenic mice. Peptides. 23(7). 1241–1247. 71 indexed citations
12.
Makarov, F. N., et al.. (2002). Impaired Processes of Working Memory in the Monkey Model of Alzheimer's Disease. Doklady Biological Sciences. 383(1-6). 106–108. 2 indexed citations
13.
Kuo, Yu‐Min, Tyler A. Kokjohn, Thomas G. Beach, et al.. (2001). Comparative Analysis of Amyloid-β Chemical Structure and Amyloid Plaque Morphology of Transgenic Mouse and Alzheimer's Disease Brains. Journal of Biological Chemistry. 276(16). 12991–12998. 216 indexed citations
14.
Kuo, Yu‐Min, Thomas G. Beach, Lucia I. Sue, et al.. (2001). The Evolution of Aβ Peptide Burden in the APP23 Transgenic Mice: Implications for Aβ Deposition in Alzheimer Disease. Molecular Medicine. 7(9). 609–618. 86 indexed citations
15.
Yan, Shi Du, Alex E. Roher, Michael P. Chaney, et al.. (2000). Cellular cofactors potentiating induction of stress and cytotoxicity by amyloid β-peptide. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1502(1). 145–157. 50 indexed citations
16.
Roher, Alex E., Jérôme Baudry, Michael O. Chaney, et al.. (2000). Oligomerization and fibril assembly of the amyloid-β protein. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1502(1). 31–43. 67 indexed citations
17.
Emmerling, Mark R., Maria Cristina Morganti-Kossmann, Thomas Kossmann, et al.. (2000). Traumatic Brain Injury Elevates the Alzheimer's Amyloid Peptide Aβ42 in Human CSF: A Possible Role for Nerve Cell Injury. Annals of the New York Academy of Sciences. 903(1). 118–122. 80 indexed citations
18.
Munson, Gregory W., Alex E. Roher, Yu‐Min Kuo, et al.. (2000). SDS-Stable Complex Formation between Native Apolipoprotein E3 and β-Amyloid Peptides. Biochemistry. 39(51). 16119–16124. 31 indexed citations
19.
Kuo, Yu‐Min, Mark R. Emmerling, Charles L. Bisgaier, et al.. (1998). Elevated Low-Density Lipoprotein in Alzheimer's Disease Correlates with Brain Aβ 1–42 Levels. Biochemical and Biophysical Research Communications. 252(3). 711–715. 265 indexed citations
20.
Roher, Alex E., et al.. (1988). Alzheimer’s disease: coated vesicles, coated pits and the amyloid-related cell. Proceedings of the Royal Society of London. Series B, Biological sciences. 232(1269). 367–373. 27 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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