James P. Guare

2.2k citations

32 papers · 1.1k · h-index 14

Impact in

Virology top 2%
- HIV Research and Treatment
Infectious Diseases top 5%
- HIV/AIDS drug development and treatment

Papers in

Organic Chemistry 19
- Click Chemistry and Applications 6
- Carbohydrate Chemistry and Synthesis 4
Infectious Diseases 17
- HIV/AIDS drug development and treatment 17

Co-authors: Joseph P. Vacca (13 shared papers)William A. Schleif (8 shared papers)Emilio A. Emini (5 shared papers)Bruce D. Dorsey (2 shared papers)Rhonda B. Levin (2 shared papers)Stacey L. McDaniel (2 shared papers)Steven D. Young (3 shared papers)Paul L. Darke (7 shared papers)
Journals: Journal of Medicinal Chemistry (10 papers)Bioorganic & Medicinal Chemistry Letters (5 papers)Tetrahedron Letters (2 papers)The Journal of Organic Chemistry (2 papers)The Journal of Immunology (1 paper)
Partner nations: United States France China

In The Last Decade

James P. Guare

31 papers receiving 1.1k citations

Peers

Countries citing papers authored by James P. Guare

Since Specialization

Citations

This map shows the geographic impact of James P. Guare's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James P. Guare with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James P. Guare more than expected).

Fields of papers citing papers by James P. Guare

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James P. Guare. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James P. Guare. The network helps show where James P. Guare may publish in the future.

Co-authors

The 25 scholars most cited alongside James P. Guare, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James P. Guare Line = papers co-authored together James P. Guare links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 32 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor Journal of Medicinal Chemistry ·Bruce D. Dorsey, Rhonda B. Levin, Stacey L. McDaniel, Joseph P. Vacca, James P. Guare, Paul L. Darke, Joan A. Zugay, Emilio A. Emini, William A. Schleif	1994	324
2	Design and Synthesis of 8-Hydroxy-[1,6]Naphthyridines as Novel Inhibitors of HIV-1 Integrase in Vitro and in Infected Cells Journal of Medicinal Chemistry ·Linghang Zhuang, John Wai, Mark W. Embrey, Thorsten E. Fisher, Melissa S. Egbertson, Linda S. Payne, James P. Guare, Joseph P. Vacca, Daria J. Hazuda, Peter J. Felock, Abigail Wolfe, Kara A. Stillmock, Marc Witmer, Gregory Moyer, William A. Schleif, Lori J. Gabryelski, Yvonne Leonard, Joseph J. Lynch, Stuart R. Michelson, Steven D. Young	2003	219
3	PD-1 Blockade in Rhesus Macaques: Impact on Chronic Infection and Prophylactic Vaccination The Journal of Immunology ·Adam C. Finnefrock, Aimin Tang, Fengsheng Li, Daniel C. Freed, Meizhen Feng, Kara S. Cox, Kara J. Sykes, James P. Guare, Michael D. Miller, David B. Olsen, Daria J. Hazuda, John W. Shiver, Danilo R. Casimiro, Tong‐Ming Fu	2009	100
4	L-687,908, a potent hydroxyethylene containing HIV protease inhibitor Journal of Medicinal Chemistry ·Joseph P. Vacca, James P. Guare, S. J. DESOLMS, William M. Sanders, Elizabeth A. Giuliani, Steven D. Young, Paul L. Darke, Irving S. Sigal, William A. Schleif	1991	97
5	Benzocycloalkyl amines as novel C-termini for HIV protease inhibitors Journal of Medicinal Chemistry ·Terry A. Lyle, Catherine M. Wiscount, James P. Guare, Wayne J. Thompson, Paul Anderson, Paul L. Darke, Joan A. Zugay, Emilio A. Emini, William A. Schleif	1991	74
6	Development of Orally Active Oxytocin Antagonists: Studies on 1-(1-{4-[1-(2-Methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl}piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and Related Pyridines Journal of Medicinal Chemistry ·Ian M. Bell, Jill M. Erb, Roger Freidinger, Steven N. Gallicchio, James P. Guare, Maribeth T. Guidotti, Rita A. Halpin, Doug W. Hobbs, Carl F. Homnick, Michelle S. Kuo, Edward V. Lis, David J. Mathre, Stuart R. Michelson, Joseph Pawluczyk, Douglas J. Pettibone, Duane R. Reiss, S. Vickers, Peter D. Williams, Carla J. Woyden	1998	47
7	A series of 5-aminosubstituted 4-fluorobenzyl-8-hydroxy-[1,6]naphthyridine-7-carboxamide HIV-1 integrase inhibitors Bioorganic & Medicinal Chemistry Letters ·James P. Guare, John Wai, Robert Gomez, Neville J. Anthony, Samson M. Jolly, Amanda R. Cortes, Joseph P. Vacca, Peter J. Felock, Kara A. Stillmock, William A. Schleif, Gregory Moyer, Lori J. Gabryelski, Lixia Jin, I‐Wu Chen, Daria J. Hazuda, Steven D. Young	2006	37
8	Design and synthesis of HIV protease inhibitors. Variations of the carboxyterminus of the HIV protease inhibitor L-682,679 Journal of Medicinal Chemistry ·S. J. DESOLMS, Elizabeth A. Giuliani, James P. Guare, Joseph P. Vacca, William M. Sanders, Samuel Graham, Jonathan Wiggins, Paul L. Darke, Irving S. Sigal	1991	33
9	Pyridinylpiperazines, a new class of selective .alpha.2-adrenoceptor antagonists Journal of Medicinal Chemistry ·Walfred S. Saari, Wasyl Halczenko, Stella W. King, Joel R. Huff, James P. Guare, C. A. HUNT, William C. Randall, Paul Anderson, Victor J. Lotti	1983	27
10	Dibenzocyclooctadiene antileukemic lignan synthesis. (.+-.)-Steganone The Journal of Organic Chemistry ·Grant R. Krow, Kalyani M. Damodaran, Edward Michener, Robert Wolf, James P. Guare	1978	18
11	Structure-affinity relationships of arylquinolizines at .alpha.-adrenoceptors Journal of Medicinal Chemistry ·Joel R. Huff, John J. Baldwin, S. J. DESOLMS, James P. Guare, Cecilia A. Hunt, William C. Randall, William H. Sanders, Steven J. Smith, Joseph P. Vacca, Matthew M. Zrada	1988	17
12	Synthesis, antiviral activity, and bioavailability studies of γ-lactam derived HIV protease inhibitors Bioorganic & Medicinal Chemistry ·Randall W. Hungate, Jenny L. Chen, Ken E. Starbuck, Joseph P. Vacca, Stacey L. McDaniel, Rhonda B. Levin, Bruce D. Dorsey, James P. Guare, M. Katharine Holloway, Willie L. Whitter, Paul L. Darke, Joan A. Zugay, William A. Schleif, Emilio A. Emini, J C Quintero, Juinn H. Lin, I‐Wu Chen, Paul Anderson, Joel R. Huff	1994	16
13	Regioselective functionalization. .beta. Substituent effects on the regioselectivity of Baeyer-Villiger oxidations of 3-substituted 2-azabicyclo[2.2.2]octan-5-ones (isoquinuclidin-5-ones) The Journal of Organic Chemistry ·Grant R. Krow, Constance A. Johnson, James P. Guare, Dennis Kubrak, Kenneth J. Henz, Donald A. Shaw, Steven W. Szczepanski, James T. Carey	1982	16
14	N-(1,3,4,6,7,12b-hexahydro-2H-benzo[b]furo[2,3-a]quinolizin-2-yl)-N-methyl-2-hydroxyethanesulfonamide: a potent and selective .alpha.2-adrenoceptor antagonist Journal of Medicinal Chemistry ·Joel R. Huff, Paul Anderson, John J. Baldwin, Bradley V. Clineschmidt, James P. Guare, Victor J. Lotti, Douglas J. Pettibone, William C. Randall, Joseph P. Vacca	1985	14
15	A convergent synthesis of novel conformationally restricted HIV-1 protease inhibitors Tetrahedron Letters ·B.Moon Kim, James P. Guare, Colleen M. Hanifin, Deborah J. Arford-Bickerstaff, Joseph P. Vacca, Richard G. Ball	1994	11
16	Design and synthesis of N-alkylated saccharins as selective α-1a adrenergic receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Jennie B. Nerenberg, Jill M. Erb, Wayne J. Thompson, Hee-Yoon Lee, James P. Guare, Peter M. Munson, Jeffrey M. Bergman, Joel R. Huff, Theodore P. Broten, Raymond S.L. Chang, Tsing B. Chen, Stacey O’Malley, Terry W. Schorn, Ann L. Scott	1998	8
17	A new hydroxyethylamine class of HIV-1 protease inhibitors with high antiviral potency and oral bioavailability Bioorganic & Medicinal Chemistry Letters ·B.Moon Kim, Joseph P. Vacca, James P. Guare, Colleen M. Hanifin, Stuart R. Michelson, P.L. Darke, Joan A. Zugay, Emilio A. Emini, William A. Schleif, Jiunn H. Lin, I‐Wu Chen, Kari Vastag, Dražen Ostović, Paul Anderson, Joel R. Huff	1994	8
18	A short synthesis of 3(r)-hydroxy-2(R)-isopropyltetrahydrothiophene: A precursor to a high-affinity P2-ligand of HIV-1 protease inhibitors Tetrahedron Letters ·B.Moon Kim, Hee‐Yoon Lee, Peter M. Munson, James P. Guare, Colleen M. McDonough	1993	8
19	Applications of microwave-assisted organic synthesis on the multigram scale. PubMed ·S. E. Wolkenberg, William D. Shipe, Craig W. Lindsley, James P. Guare, Joseph Pawluczyk	2005	7
20	Thiophene derivatives as extremely high affinity P3′ ligands for the hydroxyethylpiperazine class of HIV-1 protease inhibitors Bioorganic & Medicinal Chemistry Letters ·B. Moon Kim, James P. Guare, Joseph D. Vacca, Stuart R. Michelson, Paul L. Darke, Joan A. Zugay, Emilio A. Emini, William A. Schleif, Jiunn H. Lin, I.W. Chen, Kari Vastag, Paul Anderson, Joel R. Huff	1995	6

About James P. Guare

James P. Guare is a scholar working on Organic Chemistry, Infectious Diseases, Molecular Biology, Virology and Epidemiology, having authored 32 papers that have together received 1.1k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (17 papers), HIV Research and Treatment (8 papers), Click Chemistry and Applications (6 papers), Carbohydrate Chemistry and Synthesis (4 papers), Pneumocystis jirovecii pneumonia detection and treatment (3 papers), Receptor Mechanisms and Signaling (3 papers), Chemical Synthesis and Analysis (3 papers) and Biochemical and Molecular Research (3 papers). The work is most often cited by research in Virology (369 citations), Infectious Diseases (432 citations), Organic Chemistry (546 citations), Molecular Biology (425 citations) and Hepatology (42 citations). James P. Guare has collaborated with scholars based in United States, France and China. Frequent co-authors include Joseph P. Vacca, William A. Schleif, Emilio A. Emini, Bruce D. Dorsey, Rhonda B. Levin, Stacey L. McDaniel, Steven D. Young, Paul L. Darke, Daria J. Hazuda and S. J. DESOLMS. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, Tetrahedron Letters, The Journal of Organic Chemistry and The Journal of Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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