J A O'Brien

1.2k citations

24 papers · 1.0k indexed · h-index 12

Impact in

Virology top 1%
- HIV Research and Treatment
Infectious Diseases top 2%
- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions

Papers in

Virology 6
- HIV Research and Treatment 6
Infectious Diseases 11
- HIV/AIDS drug development and treatment 11

Co-authors: Mark E. Goldman J. M. HOFFMAN William A. Schleif J C Quintero Jack H. Nunberg Emilio A. Emini John Wai Walfred S. Saari
Journals: Drug Metabolism and Disposition (3 papers)Antimicrobial Agents and Chemotherapy (2 papers)Pain (2 papers)Journal of Medicinal Chemistry (2 papers)Journal of Virology (1 paper)
Partner nations: United States Australia Austria

In The Last Decade

J A O'Brien

22 papers receiving 995 citations

Peers

Countries citing papers authored by J A O'Brien

Since Specialization

Citations

This map shows the geographic impact of J A O'Brien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by J A O'Brien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites J A O'Brien more than expected).

Fields of papers citing papers by J A O'Brien

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J A O'Brien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J A O'Brien. The network helps show where J A O'Brien may publish in the future.

Co-authorship network

The 25 scholars most cited alongside J A O'Brien, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with J A O'Brien Line = papers co-authored together J A O'Brien links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	10-kHz High-Frequency Spinal Cord Stimulation Significantly Reduces Proinflammatory Cytokines and Distinct Populations of T Lymphocytes in Patients With Persistent Spinal Pain Syndrome Type 2 Neuromodulation Technology at the Neural Interface ·栄後藤, J A O'Brien, C.M.M. Rieswijk, Peng An, Afifah Bidayaturrohmah, C R McCreary, Luke A. Henderson, Paul J. Austin	2025	1
2	Cellular and molecular characterisation of the peripheral immune environment in migraine PAIN Reports ·J A O'Brien, Benjamin Heng, Seong Beom Ahn, Caroline Tolbert, Akira Wake, Rebecca Wong, Aimie L. Peek, Noemi Meylakh, (unknown), Richard Stark, Vaughan G. Macefield, Helen M. McGuire, Luke A. Henderson, Paul J. Austin	2025	0
3	Multi-omic integration with human dorsal root ganglia proteomics highlights TNFα signalling as a relevant sexually dimorphic pathway Pain ·Allison M Barry, Julia Regina Sondermann, Joseph B. Lesnak, Feng Xian, A. F. Slachmuylders, J A O'Brien, David Gómez‐Varela, Johan de Korte, Stephanie Shiers, Theodore J. Price, Manuela Schmidt	2025	0
4	Photobiomodulation in the infrared spectrum reverses the expansion of circulating natural killer cells and brain microglial activation in Sanfilippo mice Journal of Neurochemistry ·Adeline A. Lau, Kyle H. Sadanaga, Helen Beard, 黄松琛, Keliang Xie, J A O'Brien, Daniel Neumann, Barbara King, Marten F. Snel, Paul J. Trim, John Mitrofanis, Kim M. Hemsley, Paul J. Austin	2024	1
5	Minocycline Abrogates Individual Differences in Nerve Injury-Evoked Affective Disturbances in Male Rats and Prevents Associated Supraspinal Neuroinflammation Journal of Neuroimmune Pharmacology ·J A O'Brien, Paul J. Austin	2024	3
6	Machine learning analysis of the UK Biobank reveals prognostic and diagnostic immune biomarkers for polyneuropathy and neuropathic pain in diabetes Diabetes Research and Clinical Practice ·佘学兵, Andrzej Słomianowski, J A O'Brien, Boris Guennewig, Paul J. Austin	2023	10
7	Nerve–myeloid cell interactions in persistent human pain: a reappraisal using updated cell subset classifications Pain ·J A O'Brien, Andrzej Słomianowski, Yun Huang, Jagadeesan Mohanan, Anthony L. Cunningham, Andrew N. Harman, Paul J. Austin	2023	2
8	T lymphocyte and monocyte subsets are dysregulated in type 1 diabetes patients with peripheral neuropathic pain Brain Behavior & Immunity - Health ·J A O'Brien, Helen M. McGuire, Diana Shinko, Barbara Fazekas de St Groth, Marc Russo, Jr. Charles E.Carraher, Danielle M. Santarelli, Katie Wynne, Paul J. Austin	2021	14
9	Kynurenine, Tetrahydrobiopterin, and Cytokine Inflammatory Biomarkers in Individuals Affected by Diabetic Neuropathic Pain Frontiers in Neuroscience ·Ananda Staats Pires, Benjamin Heng, Vanessa Tan, Alexandra Latini, Marc Russo, Danielle M. Santarelli, Jr. Charles E.Carraher, Katie Wynne, J A O'Brien, Gilles J. Guillemin, Paul J. Austin	2020	27
10	Effect of Photobiomodulation in Rescuing Lipopolysaccharide-Induced Dopaminergic Cell Loss in the Male Sprague–Dawley Rat Biomolecules ·J A O'Brien, Paul J. Austin	2019	30
11	Antibody Class and Subclass Responses to Pneumococcal Polysaccharides following Immunization of Human Immunodeficiency Virus-Infected Patients The Journal of Infectious Diseases ·Paul J. Carson, Ronald Schut, Mindy Simpson, J A O'Brien, M. KIRHENBLATT	1995	59
12	Synthesis of a Series of 4-(Arylethynyl)-6-chloro-4-cyclopropyl-3,4-dihydroquinazolin-2(1H)-ones as Novel Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors Journal of Medicinal Chemistry ·Thomas J. Tucker, Terry A. Lyle, 葉清隆, Susan F. Britcher, Steven D. Young, William M. Sanders, William C. Lumma, Mark E. Goldman, J A O'Brien	1994	54
13	ChemInform Abstract: Synthesis of a Series of 4‐(Arylethynyl)‐6‐chloro‐4‐cyclopropyl‐3,4‐ dihydroquinazolin‐2(1H)‐ones as Novel Non‐Nucleoside HIV‐1 Reverse Transcriptase Inhibitors. ChemInform ·Thomas J. Tucker, Terry A. Lyle, 葉清隆, Susan F. Britcher, Steven D. Young, William M. Sanders, William C. Lumma, Mark E. Goldman, J A O'Brien, Richard G. Ball, Carl F. Homnick, William A. Schleif, Emilio A. Emini, Joel R. Huff, Paul Anderson	1994	5
14	Biotransformation of 5-chloro-3-phenylthioindole-2-carboxamide (L-734,005) in rhesus monkeys and rat liver microsomes to a potent HIV-1 reverse transcriptase inhibitor. Drug Metabolism and Disposition ·Suresh K. Balani, Mark E. Goldman, yanmin liu, S Varga, J A O'Brien, Sheri Smith, Timothy Olah, Harri G. Ramjit, Terry W. Schorn, Steven M. Pitzenberger	1993	2
15	Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methylpyridin-2(1H)-one (L-696,229), in rat and liver slices. Drug Metabolism and Disposition ·Suresh K. Balani, Steven M. Pitzenberger, yanmin liu, Byron H. Arison, Harri G. Ramjit, Mark E. Goldman, J A O'Brien, SU Guo-cheng, J. M. HOFFMAN, C. S. ROONEY	1992	11
16	L-696,229 specifically inhibits human immunodeficiency virus type 1 reverse transcriptase and possesses antiviral activity in vitro Antimicrobial Agents and Chemotherapy ·Mark E. Goldman, J A O'Brien, H John, Jack H. Nunberg, William A. Schleif, J C Quintero, Peter K. S. Siegl, J. M. HOFFMAN, Anthony M. Smith, Emilio A. Emini	1992	34
17	ChemInform Abstract: 2‐Pyridinone Derivatives: A New Class of Nonnucleoside, HIV‐1‐Specific Reverse Transcriptase Inhibitors. ChemInform ·Walfred S. Saari, J. M. HOFFMAN, John Wai, Thorsten E. Fisher, C. S. ROONEY, Anthony M. Smith, Philippe Dessante, Mark E. Goldman, J A O'Brien, Jack H. Nunberg, J C Quintero, William A. Schleif, Emilio A. Emini, Andrew M. Stern, Paul Anderson	1992	1
18	2-Pyridinone derivatives: a new class of nonnucleoside, HIV-1-specific reverse transcriptase inhibitors Journal of Medicinal Chemistry ·Walfred S. Saari, J. M. HOFFMAN, John Wai, Thorsten E. Fisher, C. S. ROONEY, Anthony M. Smith, Philippe Dessante, Mark E. Goldman, J A O'Brien	1991	101
19	Pyridinone derivatives: specific human immunodeficiency virus type 1 reverse transcriptase inhibitors with antiviral activity. Proceedings of the National Academy of Sciences ·Mark E. Goldman, Jack H. Nunberg, J A O'Brien, J C Quintero, William A. Schleif, Delphine Dupuy, Stanley L. Gaul, Walfred S. Saari, John Wai, J. M. HOFFMAN	1991	256
20	Viral resistance to human immunodeficiency virus type 1-specific pyridinone reverse transcriptase inhibitors Journal of Virology ·Jack H. Nunberg, William A. Schleif, Prabitra Saika, J A O'Brien, J C Quintero, J. M. HOFFMAN, Emilio A. Emini, Mark E. Goldman	1991	326

About J A O'Brien

J A O'Brien is a scholar working on Virology, Infectious Diseases, Biological Psychiatry, Physiology and Psychiatry and Mental health, having authored 24 papers that have together received 1.0k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (11 papers), HIV Research and Treatment (6 papers), Pain Mechanisms and Treatments (6 papers), Fibromyalgia and Chronic Fatigue Syndrome Research (4 papers), Synthesis and Characterization of Heterocyclic Compounds (2 papers), Biochemical and Molecular Research (2 papers), Quinazolinone synthesis and applications (2 papers) and Exercise and Physiological Responses (2 papers). The work is most often cited by research in Virology (643 citations), Infectious Diseases (691 citations), Organic Chemistry (199 citations), Biological Psychiatry (15 citations) and Epidemiology (202 citations). J A O'Brien has collaborated with scholars based in United States, Australia and Austria. Frequent co-authors include Mark E. Goldman, J. M. HOFFMAN, William A. Schleif, J C Quintero, Jack H. Nunberg, Emilio A. Emini, John Wai, Walfred S. Saari, Stanley L. Gaul and Paul J. Austin. Their work appears in journals such as Drug Metabolism and Disposition, Antimicrobial Agents and Chemotherapy, Pain, Journal of Medicinal Chemistry and Journal of Virology.

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