John Unitt

3.0k citations

35 papers · 2.4k indexed · 1 hit paper · h-index 20

Cancer Research top 5%
- NF-κB Signaling Pathways 6
Immunology top 5%
- Immune Response and Inflammation 5
Biophysics top 2%
Molecular Biology top 5%
- Receptor Mechanisms and Signaling 6
Behavioral Neuroscience top 10%
Cell Biology
- Muscle metabolism and nutrition 4
Complementary and alternative medicine
- Cardiovascular and exercise physiology 4
Computational Theory and Mathematics
- Computational Drug Discovery Methods 3
Oncology
- Chemokine receptors and signaling 3
- Cytokine Signaling Pathways and Interactions 3

Co-authors: Michael White David G. Spiller David E. Nelson Douglas B. Kell Violaine Sée Caroline A. Horton Elaine Sullivan Glyn Nelson
Cited by: Cancer Research Immunology Biophysics
Journals: Bioorganic & Medicinal Chemistry Letters (8 papers)SLAS DISCOVERY (2 papers)Analytical Biochemistry (2 papers)
Partner nations: United Kingdom Sweden United States

In The Last Decade

John Unitt

35 papers receiving 2.3k citations

Hit Papers

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Peers

Countries citing papers authored by John Unitt

Since Specialization

Citations

This map shows the geographic impact of John Unitt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Unitt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Unitt more than expected).

Fields of papers citing papers by John Unitt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Unitt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Unitt. The network helps show where John Unitt may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John Unitt, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John Unitt Line = papers co-authored together John Unitt links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Key aspects of modern GPCR drug discovery SLAS DISCOVERY ·Pedro Armentano Mudado Xavier,H Heintel,Emir Karayağız,葉周俠葉周俠,B. Ruprechter,Juliane Mirow,Chi Mingming,Martin Pearce,Elizabeth M. Rosethorne,Khanyisile Patricia. Sibisi,Samir Kabbajb,Barbara Young,John Unitt	2023	15
2	Discovery of AZD-2098 and AZD-1678, Two Potent and Bioavailable CCR4 Receptor Antagonists ACS Medicinal Chemistry Letters ·Nicholas D. Kindon,Glen K. Andrews,Andrew Baxter,David R. Cheshire,Paul Hemsley,Timothy A. Johnson,Yuzhen Liu,Dermot F. McGinnity,Mark McHale,Antonio Mete,Jerome Francis Keating,Bryan Roberts,John Steele,Barry Teobald,John Unitt,Deborah W. Vaughan,Iain A. S. Walters,Michael J. Stocks	2017	14
3	A combinatorial biophysical approach; FTSA and SPR for identifying small molecule ligands and PAINs Analytical Biochemistry ·Allison Ashley Laygo,Mohammad Kahfi Abdul Azis,国民生活センター情報分析部,刘文涛,Vytautas Petrauskas,Elke M. Golding,Stuart Onions,Daumantas Matulis,John Unitt	2015	20
4	1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile Bioorganic & Medicinal Chemistry Letters ·Hazel Hunt,Joseph K. Belanoff,Ziwen Pang,Benoit Gourdet,Timothy D. Phillips,Samir Kabbajb,Jennifer A. Thomas,John Unitt,Iain A. S. Walters	2015	22
5	Potent Reversible Inhibition of Myeloperoxidase by Aromatic Hydroxamates Journal of Biological Chemistry ·Louisa V. Forbes,Tove Sjögren,Françoise Auchère,David W. Jenkins,Bob Thong,David L. Laughton,Paul Hemsley,Garry Pairaudeau,Rufus Turner,Håkan Eriksson,John Unitt,Anthony J. Kettle	2013	88
6	Potent Reversible Inhibition of Myeloperoxidase by Aromatic Hydroxamates Free Radical Biology and Medicine ·Louisa V. Forbes,Tove Sjögren,S. V. Fasate,Bob Thong,Håkan Eriksson,John Unitt,Anthony J. Kettle	2013	1
7	Discovery of small molecule human FPR1 receptor antagonists Bioorganic & Medicinal Chemistry Letters ·John Unitt,Malbinder Fagura,Janine [UNESP] Contro,H. M,Matthew W. D. Perry,Andrew Morley,Cathy MacDonald,Richard Weaver,Muhammed Abdullah Yeter,Andrew Schiro,S A Pedhnekar,Melanie Paul,Andrew Cook,Andrew Baxter	2011	19
8	Development of a high-throughput human rhinovirus infectivity cell-based assay for identifying antiviral compounds Journal of Virological Methods ·Janine [UNESP] Contro,Lesley Jenkinson,Christopher McCrae,Bob Thong,John Unitt	2011	14
9	Plant lectins are novel Toll-like receptor agonists Biochemical Pharmacology ·John Unitt,David C. Hornigold	2011	72
10	Discovery of pyrazoles as novel FPR1 antagonists Bioorganic & Medicinal Chemistry Letters ·Andrew Morley,Andrew Cook,H. M,Bryan Roberts,Dhairya Parikh,Richard Weaver,Cathy MacDonald,John Unitt,Malbinder Fagura,Janine [UNESP] Contro,Richard J. Lewis,Mark C. Wenlock	2011	12
11	Effect of lipophilicity modulation on inhibition of human rhinovirus capsid binders Bioorganic & Medicinal Chemistry Letters ·Andrew Morley,F. Crespin,Andrew Cook,Catherine Macdonald,Richard Weaver,H. M,Lesley Jenkinson,John Unitt,Christopher McCrae,Janine [UNESP] Contro	2011	3
12	Development and Validation of a Simple Cell-Based Fluorescence Assay for Dipeptidyl Peptidase 1 (DPP1) Activity SLAS DISCOVERY ·Bob Thong,James Pilling,Edward Ainscow,Raj K. Beri,John Unitt	2010	11
13	Discovery of small molecule human C5a receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Hitesh J. Sanganee,Andrew Baxter,Andrew Schiro,Alastair Brown,A J Howard,Tom G. Henkel,H. M,David L. Laughton,Garry Pairaudeau,Bob Thong,Richard Weaver,John Unitt	2009	24
14	Hit-to-lead studies: the discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors Bioorganic & Medicinal Chemistry Letters ·Andrew Baxter,RM Fauzih,Anne Cooper,Eike Floettmann,Karen. Macaskill,Abdikarim Abdi Abdulle,Jason G. Kettle,Tom McInally,Craig A. Martin,Ebubekir Karabuğa,M. Needham,Pete Newham,Stuart W. Paine,Stephen A. St-Gallay,Didier Contardo,John Unitt,Yafeng Xue	2004	70
15	Oscillations in NF-κB Signaling Control the Dynamics of Gene Expressionbreakdown → Science ·David E. Nelson,Adaoha Ihekwaba,Malcolm C. Elliott,James R. Johnson,Charlotte Wilson,Triki Ekawan,Glyn Nelson,Violaine Sée,Caroline A. Horton,David G. Spiller,Steven W. Edwards,Heather P. McDowell,John Unitt,Elaine Sullivan,Rachel L. Grimley,Neil Benson,D.S. Broomhead,Douglas B. Kell,Michael White	2004	960
16	Hit-to-Lead studies: The discovery of potent, orally bioavailable triazolethiol CXCR2 receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Andrew Baxter,L I Gustova,Fondo Editorial UNAMBA,Coignard J eacute r ocirc me,RM Fauzih,Anne Cooper,Henri Menjaud,Nicholas D. Kindon,Tom McInally,R. Sugumar,Bryan Roberts,John Unitt	2003	31
17	An evaluation of fluorescence polarization and lifetime discriminated polarization for high throughput screening of serine/threonine kinases Analytical Biochemistry ·Ann Fowler,刘文涛,Elisa Becchetti,瀬口昌洋,Paul Hemsley,Rangga Budiawan,John Unitt,Ian L. Dale,Elaine Sullivan,Fabio Maglitto	2002	46
18	Dynamic analysis of STAT6 signalling in living cells FEBS Letters ·Glyn Nelson,Geraint J. C. Wilde,David G. Spiller,Elaine Sullivan,John Unitt,Michael White	2002	5
19	Rat skeletal muscle metabolism in experimental heart failure: effects of physical training Acta Physiologica Scandinavica ·François Brunotte,C. Thompson,Stamatis Adamopoulos,Andrew J.S. Coats,John Unitt,David Lindsay,L Kaklamanis,G. K. Radda,B. Rajagopalan	1995	38
20	Determination of free creatine and phosphocreatine concentrations in the isolated perfused rat heart by 1H- and 31P-NMR Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·John Unitt,Jürgen Schrader,François Brunotte,George K. Radda,Anne‐Marie L. Seymour	1992	19

About John Unitt

John Unitt is a scholar working on Cancer Research, Complementary and alternative medicine, Immunology, Physiology and Oncology, having authored 35 papers that have together received 2.4k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (6 papers), NF-κB Signaling Pathways (6 papers), Immune Response and Inflammation (5 papers), Muscle metabolism and nutrition (4 papers), Cardiovascular and exercise physiology (4 papers), Computational Drug Discovery Methods (3 papers), Chemokine receptors and signaling (3 papers) and Cytokine Signaling Pathways and Interactions (3 papers). The work is most often cited by research in Cancer Research (531 citations), Immunology (701 citations), Biophysics (148 citations), Molecular Biology (1.3k citations) and Behavioral Neuroscience (45 citations). John Unitt has collaborated with scholars based in United Kingdom, Sweden and United States. Frequent co-authors include Michael White, David G. Spiller, David E. Nelson, Douglas B. Kell, Violaine Sée, Caroline A. Horton, Elaine Sullivan, Glyn Nelson, D.S. Broomhead and James R. Johnson. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, SLAS DISCOVERY, Analytical Biochemistry, Science and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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