James K. Liao

43.4k total citations · 12 hit papers
280 papers, 35.1k citations indexed

About

James K. Liao is a scholar working on Molecular Biology, Physiology and Surgery. According to data from OpenAlex, James K. Liao has authored 280 papers receiving a total of 35.1k indexed citations (citations by other indexed papers that have themselves been cited), including 127 papers in Molecular Biology, 74 papers in Physiology and 69 papers in Surgery. Recurrent topics in James K. Liao's work include Nitric Oxide and Endothelin Effects (63 papers), Protein Kinase Regulation and GTPase Signaling (58 papers) and Lipoproteins and Cardiovascular Health (55 papers). James K. Liao is often cited by papers focused on Nitric Oxide and Endothelin Effects (63 papers), Protein Kinase Regulation and GTPase Signaling (58 papers) and Lipoproteins and Cardiovascular Health (55 papers). James K. Liao collaborates with scholars based in United States, Japan and Germany. James K. Liao's co-authors include Ulrich Laufs, Masao Takemoto, Haibing Peng, Peter Libby, Yoshiyuki Rikitake, Qian Zhou, Tommaso Simoncini, Martin Spiecker, Koichi Node and Jorge Plutzky and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

James K. Liao

278 papers receiving 34.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors

1998 1.5k citations James K. Liao et al. Circulation profile →
PLEIOTROPIC EFFECTS OF STATINS

2004 1.5k citations James K. Liao et al. profile →
Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

1995 1.4k citations James K. Liao et al. Journal of Clinical Investigation profile →
Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

2000 1.2k citations Tommaso Simoncini, James K. Liao et al. profile →
Pleiotropic Effects of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors

2001 1.1k citations Masao Takemoto, James K. Liao profile →
Anti-inflammatory Properties of Cytochrome P450 Epoxygenase-Derived Eicosanoids

1999 1.0k citations Koichi Node, Martin Spiecker et al. profile →
Pleiotropic Effects of Statins on the Cardiovascular System

2017 877 citations James K. Liao et al. Circulation Research profile →
Post-transcriptional Regulation of Endothelial Nitric Oxide Synthase mRNA Stability by Rho GTPase

1998 866 citations James K. Liao et al. profile →
Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

1998 817 citations Zhihong Huang, Michael A. Moskowitz et al. profile →
Induction and Stabilization of IκBα by Nitric Oxide Mediates Inhibition of NF-κB

1995 580 citations James K. Liao et al. profile →
Pleiotropic effects of statin therapy: molecular mechanisms and clinical results

2008 476 citations James K. Liao et al. profile →
Pleiotropic Effects of Statins - Basic Research and Clinical Perspectives -

2010 447 citations Qian Zhou, James K. Liao profile →

Peers

Countries citing papers authored by James K. Liao

Since Specialization

Citations

This map shows the geographic impact of James K. Liao's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James K. Liao with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James K. Liao more than expected).

Fields of papers citing papers by James K. Liao

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James K. Liao. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James K. Liao. The network helps show where James K. Liao may publish in the future.

Co-authorship network of co-authors of James K. Liao

This figure shows the co-authorship network connecting the top 25 collaborators of James K. Liao. A scholar is included among the top collaborators of James K. Liao based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James K. Liao. James K. Liao is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Role of Rho-Associated Kinase in the Pathophysiology of Cerebral Cavernous Malformations 2024 ·Neurology Genetics ·Cenk Ayata, Helen Kim, Leslie Morrison, James K. Liao, Juan Gutierrez, Miguel A. López‐Toledano, Enrique Carrazana, Adrián L. Rabinowicz, Issam A. Awad	6
2	Impaired Cognitive Performance in Endothelial Nitric Oxide Synthase Knockout Mice After Ischemic Stroke 2018 ·American Journal of Physical Medicine & Rehabilitation ·Shanshan Li, Yao Wang, Ze D. Jiang, (unknown), James K. Liao, Kaari A. Lynch, Ross Zafonte, Lisa J. Wood, Qing Mei Wang	24
3	Abstract 18253: Reliance on Electrocardiogram Computer Algorithm Interpretation to Activate ST Elevation Myocardial Infarction Processes of Care and Initiate Reperfusion Therapy: Impact on False Activation 2017 ·Circulation ·Mohammad Al‐Akchar, Frank V. Aguirre, (unknown), (unknown), Stephanie A. Besser, Jenny Chambers, Sachin S. Goel, (unknown), Rohan Kalathiya, Raed Al-Dallow, (unknown), James K. Liao	1
4	Role of ROCK 2 in CD 4 ⁺ cells in allergic airways responses in mice 2016 ·Clinical & Experimental Allergy ·David I. Kasahara, Joel Mathews, (unknown), Allison P. Wurmbrand, James K. Liao, Stephanie A. Shore	3
5	MnTBAP increases BMPR-II expression in endothelial cells and attenuates vascular inflammation 2016 ·Vascular Pharmacology ·Qian Zhou, (unknown), (unknown), (unknown), Franziska Pankratz, Christoph B. Olivier, Christoph Bode, James K. Liao, Martin Moser	9
6	Abstract 20699: Reduction of Endothelial Arnt Mediates Vascular Dysfunction in Diabetes 2016 ·Circulation ·Maura Knapp, Mei Zheng, Nikola Sladojević, Qiong Zhao, James K. Liao, Rongxue Wu	1
7	Abstract 19339: ROCK2 Mediates the Uptake of Fatty Acids through the Transcriptional Regulation of CD36 2014 ·Circulation ·(unknown), (unknown), (unknown), James K. Liao	1
8	Increased Rho Kinase Activity in Congestive Heart Failure 2012 ·European Journal of Heart Failure ·Ming Dong, James K. Liao, Fang Fang, Alex Pui‐Wai Lee, (unknown), Ming Liu, Cheuk‐Man Yu	36
9	Role of Rho kinase isoforms in murine allergic airway responses 2011 ·European Respiratory Journal ·Mei‐Jun Zhu, Po‐Yu Liu, David I. Kasahara, Alison S. Williams, Norah G. Verbout, Andrew J. Halayko, (unknown), Takeshi Shoji, Elizabeth Williams, (unknown), Stephanie A. Shore, James K. Liao	31
10	Abstract 1426: Decrease Basal Metabolism and Energy Expenditure and Increase Obesity in Mice with Targeted Deletion of ROCK2 2008 ·Circulation ·(unknown), James K. Liao	1
11	Critical Role of Endothelial Notch1 Signaling in Postnatal Angiogenesis 2006 ·Circulation Research ·Kyosuke Takeshita, Minoru Satoh, Masaaki Ii, Marcy Silver, Florian P. Limbourg, Yasushi Mukai, Yoshiyuki Rikitake, Freddy Radtke, Thomas Gridley, Douglas W. Losordo, James K. Liao	200
12	Transcription factor CHF1/Hey2 suppresses cardiac hypertrophy through an inhibitory interaction with GATA4 2006 ·American Journal of Physiology-Heart and Circulatory Physiology ·Xiang Fan, Yasuhiko Sakata, Lei Cui, (unknown), Hironori Nakagami, James K. Liao, Ronglih Liao, Michael T. Chin	48
13	A novel pleiotropic effect of statins: prevention of cardiac hypertrophy by cholesterol-independent mechanisms 2003 ·Annals of Medicine ·Hironori Nakagami, Kristin Jensen, James K. Liao	73
14	Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids 2002 ·Journal of Clinical Investigation ·Florian P. Limbourg, Zhihong Huang, Jean-Christophe Plumier, Tommaso Simoncini, Masayuki Fujioka, Jan Tuckermann, Günther Schütz, Michael A. Moskowitz, James K. Liao	151
15	Isoprenoids as mediators of the biological effects of statins 2002 ·Journal of Clinical Investigation ·James K. Liao	310
16	Rapid nontranscriptional activation of endothelial nitric oxide synthase mediates increased cerebral blood flow and stroke protection by corticosteroids 2002 ·Journal of Clinical Investigation ·Florian P. Limbourg, Zhihong Huang, Jean-Christophe Plumier, Tommaso Simoncini, Masayuki Fujioka, Jan Tuckermann, Günther Schütz, Michael A. Moskowitz, James K. Liao	18
17	Isoprenoids as mediators of the biological effects of statins 2002 ·Journal of Clinical Investigation ·James K. Liao	366
18	Statins as antioxidant therapy for preventing cardiac myocyte hypertrophy 2001 ·Journal of Clinical Investigation ·Masao Takemoto, Koichi Node, Hironori Nakagami, Yulin Liao, Michael Grimm, (unknown), Masafumi Kitakaze, James K. Liao	55
19	Simvastatin upregulates coronary vascular endothelial nitric oxide production in conscious dogs 2000 ·American Journal of Physiology-Heart and Circulatory Physiology ·Seema Mital, Xiao–Ping Zhang, Gong Zhao, Robert Bernstein, Carolyn J. Smith, David Fulton, William C. Sessa, James K. Liao, Thomas H. Hintze	85
20	A Functional Role of IκB-ε in Endothelial Cell Activation 2000 ·The Journal of Immunology ·Martin Spiecker, Harald Darius, James K. Liao	57

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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