Jean‐Charles Fruchart

39.8k total citations · 7 hit papers
382 papers, 31.8k citations indexed

About

Jean‐Charles Fruchart is a scholar working on Molecular Biology, Surgery and Endocrinology, Diabetes and Metabolism. According to data from OpenAlex, Jean‐Charles Fruchart has authored 382 papers receiving a total of 31.8k indexed citations (citations by other indexed papers that have themselves been cited), including 182 papers in Molecular Biology, 178 papers in Surgery and 125 papers in Endocrinology, Diabetes and Metabolism. Recurrent topics in Jean‐Charles Fruchart's work include Peroxisome Proliferator-Activated Receptors (135 papers), Diabetes, Cardiovascular Risks, and Lipoproteins (108 papers) and Lipoproteins and Cardiovascular Health (106 papers). Jean‐Charles Fruchart is often cited by papers focused on Peroxisome Proliferator-Activated Receptors (135 papers), Diabetes, Cardiovascular Risks, and Lipoproteins (108 papers) and Lipoproteins and Cardiovascular Health (106 papers). Jean‐Charles Fruchart collaborates with scholars based in France, United States and United Kingdom. Jean‐Charles Fruchart's co-authors include Bart Staels, Giulia Chinetti, Johan Auwerx, Patrick Duriez, Inès Pineda‐Torra, Kristina Schoonjans, Philippe Gervois, Philippe Delerive, Jamila Najïb and Jean Dallongeville and has published in prestigious journals such as Nature, Science and Journal of Biological Chemistry.

In The Last Decade

Jean‐Charles Fruchart

378 papers receiving 30.9k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mechanism of Action of Fibrates on Lipid and Lipoprotein Metabolism

1998 1.4k citations Bart Staels, Johan Auwerx et al. profile →
The Organization, Promoter Analysis, and Expression of the Human PPARγ Gene

1997 1.0k citations Lluís Fajas, Eric Raspé et al. Journal of Biological Chemistry profile →
PPAR-α and PPAR-γ activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

2001 987 citations Giulia Chinetti, Inès Pineda‐Torra et al. profile →
Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators

1998 974 citations Bart Staels, Inès Pineda‐Torra et al. profile →
Activation of Proliferator-activated Receptors α and γ Induces Apoptosis of Human Monocyte-derived Macrophages

1998 797 citations Giulia Chinetti, Inès Pineda‐Torra et al. Journal of Biological Chemistry profile →
Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation

2000 786 citations Giulia Chinetti, Jean‐Charles Fruchart et al. profile →
An Apolipoprotein Influencing Triglycerides in Humans and Mice Revealed by Comparative Sequencing

2001 747 citations L Pennacchio, Michael Olivier et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jean‐Charles Fruchart France	94	15.8k	10.3k	7.3k	5.5k	5.0k	382	31.8k
Jan L. Breslow United States	96	9.7k 0.6×	12.0k 1.2×	8.7k 1.2×	3.4k 0.6×	4.1k 0.8×	266	29.9k
Hitoshi Shimano Japan	77	11.0k 0.7×	8.8k 0.8×	4.8k 0.7×	4.2k 0.8×	4.6k 0.9×	380	24.0k
James K. Liao United States	96	11.5k 0.7×	9.1k 0.9×	4.5k 0.6×	6.4k 1.2×	2.9k 0.6×	280	35.1k
Jay D. Horton United States	74	15.9k 1.0×	16.6k 1.6×	7.6k 1.0×	5.4k 1.0×	11.8k 2.4×	123	37.7k
Louis M. Havekes Netherlands	84	7.5k 0.5×	7.7k 0.7×	5.8k 0.8×	5.3k 1.0×	4.0k 0.8×	422	23.1k
Morris F. White United States	121	32.8k 2.1×	12.4k 1.2×	10.6k 1.5×	11.5k 2.1×	6.5k 1.3×	346	51.4k
Gerd Assmann Germany	80	7.6k 0.5×	12.1k 1.2×	9.5k 1.3×	2.3k 0.4×	2.6k 0.5×	455	25.9k
Alan M. Fogelman United States	92	8.5k 0.5×	10.7k 1.0×	6.6k 0.9×	2.2k 0.4×	3.8k 0.8×	266	31.5k
Ira J. Goldberg United States	84	9.1k 0.6×	5.9k 0.6×	7.5k 1.0×	5.1k 0.9×	3.9k 0.8×	336	25.9k
Alan R. Tall United States	119	16.9k 1.1×	24.6k 2.4×	12.8k 1.8×	3.5k 0.6×	5.8k 1.2×	365	45.3k

Countries citing papers authored by Jean‐Charles Fruchart

Since Specialization

Citations

This map shows the geographic impact of Jean‐Charles Fruchart's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jean‐Charles Fruchart with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jean‐Charles Fruchart more than expected).

Fields of papers citing papers by Jean‐Charles Fruchart

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jean‐Charles Fruchart. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jean‐Charles Fruchart. The network helps show where Jean‐Charles Fruchart may publish in the future.

Co-authorship network of co-authors of Jean‐Charles Fruchart

This figure shows the co-authorship network connecting the top 25 collaborators of Jean‐Charles Fruchart. A scholar is included among the top collaborators of Jean‐Charles Fruchart based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jean‐Charles Fruchart. Jean‐Charles Fruchart is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

1.

Sparatore, Anna, Cristina Godio, Elena Perrino, et al.. (2006). [4‐(2H‐1,2,3‐Benzotriazol‐2‐yl)phenoxy]alkanoic Acids as Agonists of Peroxisome Proliferator‐Activated Receptors (PPARs). Chemistry & Biodiversity. 3(4). 385–395. 12 indexed citations

2.

Helleboid‐Chapman, Audrey, Stéphane Helleboid, Heidelinde Jäkel, et al.. (2006). Glucose regulates LXRα subcellular localization and function in rat pancreatic β-cells. Cell Research. 16(7). 661–670. 17 indexed citations

3.

Billiet, Ludivine, Christophe Furman, Guilhem Larigauderie, et al.. (2005). Extracellular Human Thioredoxin-1 Inhibits Lipopolysaccharide-induced Interleukin-1β Expression in Human Monocyte-derived Macrophages. Journal of Biological Chemistry. 280(48). 40310–40318. 57 indexed citations

4.

Genoux, Annelise, Philippe Gervois, Corinne Rommens, et al.. (2004). Apolipoprotein A5 is an inflammatory responsive gene down-regulated by tumor necrosis factor alpha and interleukin-1. Lawrence Berkeley National Laboratory. 3 indexed citations

5.

Helleboid‐Chapman, Audrey, Heidelinde Jäkel, Corinne Rommens, et al.. (2004). Phosphorylation-dependent down-regulation of apolipoprotein A5 by insulin. Molecular and Cellular Biology. 25(4). 1 indexed citations

6.

Claudel, Thierry, Yusuke Inoue, Olivier Barbier, et al.. (2003). Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression. Gastroenterology. 125(2). 544–555. 224 indexed citations

7.

Gervois, Philippe & Jean‐Charles Fruchart. (2003). PPARγ : un récepteur nucléaire majeur de l’adipogenèse. médecine/sciences. 19(1). 20–22. 3 indexed citations

8.

Chevé, Gwénaël, Patrick Duriez, Jean‐Charles Fruchart, et al.. (2002). Antioxidant activity of pinoline analogues in the LDL oxidation model. Medicinal Chemistry Research. 11(7). 361–379. 13 indexed citations

9.

Fruchart, Jean‐Charles & Patrick Duriez. (2002). HDL and triglyceride as therapeutic targets. Current Opinion in Lipidology. 13(6). 605–616. 44 indexed citations

10.

Claudel, Thierry, Ekkehard Sturm, Hélène Duez, et al.. (2002). Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element. Journal of Clinical Investigation. 109(7). 961–971. 24 indexed citations

11.

Singaraja, Roshni R., Catherine Fiévet, Graciela Castro, et al.. (2002). Increased ABCA1 activity protects against atherosclerosis. Journal of Clinical Investigation. 110(1). 35–42. 15 indexed citations

12.

Singaraja, Roshni R., Catherine Fiévet, Graciela Castro, et al.. (2002). Increased ABCA1 activity protects against atherosclerosis. Journal of Clinical Investigation. 110(1). 35–42. 206 indexed citations

13.

Claudel, Thierry, Ekkehard Sturm, Hélène Duez, et al.. (2002). Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element. Journal of Clinical Investigation. 109(7). 961–971. 255 indexed citations

14.

Pennacchio, L, Michael Olivier, Jaroslav A. Hubáček, et al.. (2001). An Apolipoprotein Influencing Triglycerides in Humans and Mice Revealed by Comparative Sequencing. Science. 294(5540). 169–173. 747 indexed citations breakdown →

15.

Pineda‐Torra, Inès, Giulia Chinetti, Caroline Duval, Jean‐Charles Fruchart, & Bart Staels. (2001). Peroxisome proliferator-activated receptors: from transcriptional control to clinical practice. Current Opinion in Lipidology. 12(3). 245–254. 170 indexed citations

16.

Guerre-Millo, Michèle, Philippe Gervois, Eric Raspé, et al.. (2000). PPARa activators improve insulin sensitivity and reduce adiposity. Journal of Biological Chemistry. 93 indexed citations

17.

Fajas, Lluís, Jean‐Charles Fruchart, & Johan Auwerx. (1998). PPARγ3 mRNA: a distinct PPARγ mRNA subtype transcribed from an independent promoter. FEBS Letters. 438(1-2). 55–60. 285 indexed citations

18.

Leroy, Arnaud, Jean Dallongeville, & Jean‐Charles Fruchart. (1995). Apolipoprotein A-I-containing lipoproteins and atherosclerosis. Current Opinion in Lipidology. 6(5). 281–285. 23 indexed citations

19.

Bard, Jean‐Marie, H J Parra, Olivier Ziegler, et al.. (1992). A multicenter comparison of the effects of simvastatin and fenofibrate therapy in severe primary hypercholesterolemia, with particular emphasis on lipoproteins defined by their apolipoprotein composition. Metabolism. 41(5). 498–503. 67 indexed citations

20.

Dehouck, Marie‐Pierre, Stéphane Méresse, Pierre Delorme, Jean‐Charles Fruchart, & Roméo Cecchelli. (1990). An Easier, Reproducible, and Mass‐Production Method to Study the Blood–Brain Barrier In Vitro. Journal of Neurochemistry. 54(5). 1798–1801. 425 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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