James H. Wikel

2.5k total citations
38 papers, 1.8k citations indexed

About

James H. Wikel is a scholar working on Organic Chemistry, Molecular Biology and Computational Theory and Mathematics. According to data from OpenAlex, James H. Wikel has authored 38 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Organic Chemistry, 13 papers in Molecular Biology and 13 papers in Computational Theory and Mathematics. Recurrent topics in James H. Wikel's work include Computational Drug Discovery Methods (13 papers), Drug Transport and Resistance Mechanisms (7 papers) and Analytical Chemistry and Chromatography (6 papers). James H. Wikel is often cited by papers focused on Computational Drug Discovery Methods (13 papers), Drug Transport and Resistance Mechanisms (7 papers) and Analytical Chemistry and Chromatography (6 papers). James H. Wikel collaborates with scholars based in United States and Denmark. James H. Wikel's co-authors include Sean Ekins, Steven Wrighton, Gianpaolo Bravi, R. Dustan Sarazan, William Crumb, Barbara J. Ring, Jennifer S. Gillespie, Peter W. Swaan, Chris L. Waller and Gabriele Cruciani and has published in prestigious journals such as Journal of Medicinal Chemistry, Journal of Pharmacology and Experimental Therapeutics and The Journal of Organic Chemistry.

In The Last Decade

James H. Wikel

38 papers receiving 1.8k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James H. Wikel United States	19	734	730	532	518	317	38	1.8k
Marcel J. de Groot United Kingdom	23	927 1.3×	835 1.1×	874 1.6×	320 0.6×	413 1.3×	39	2.2k
Gian Camenisch Switzerland	26	871 1.2×	440 0.6×	525 1.0×	915 1.8×	278 0.9×	56	2.5k
Rupert P. Austin United Kingdom	17	602 0.8×	516 0.7×	627 1.2×	549 1.1×	367 1.2×	29	1.8k
B. Michael Silber United States	21	691 0.9×	229 0.3×	650 1.2×	454 0.9×	306 1.0×	49	2.0k
Ulf Bredberg Sweden	21	454 0.6×	262 0.4×	352 0.7×	621 1.2×	126 0.4×	33	1.9k
Cuyue Tang United States	25	631 0.9×	206 0.3×	839 1.6×	627 1.2×	126 0.4×	66	2.2k
Patrizia Crivori Italy	15	674 0.9×	670 0.9×	233 0.4×	314 0.6×	346 1.1×	27	1.6k
David D. Christ United States	25	537 0.7×	129 0.2×	472 0.9×	335 0.6×	126 0.4×	49	1.9k
Kamlesh P. Vyas United States	26	606 0.8×	211 0.3×	854 1.6×	494 1.0×	153 0.5×	58	2.3k
Fabio Broccatelli United States	18	455 0.6×	435 0.6×	328 0.6×	404 0.8×	198 0.6×	30	1.5k

Countries citing papers authored by James H. Wikel

Since Specialization

Citations

This map shows the geographic impact of James H. Wikel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James H. Wikel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James H. Wikel more than expected).

Fields of papers citing papers by James H. Wikel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James H. Wikel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James H. Wikel. The network helps show where James H. Wikel may publish in the future.

Co-authorship network of co-authors of James H. Wikel

This figure shows the co-authorship network connecting the top 25 collaborators of James H. Wikel. A scholar is included among the top collaborators of James H. Wikel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James H. Wikel. James H. Wikel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

1.

Pasha, Sheik Pran Babu Sardar, Kamakshi Sishtla, Rania S. Sulaiman, et al.. (2018). Ref-1/APE1 Inhibition with Novel Small Molecules Blocks Ocular Neovascularization. PubMed Central. 38 indexed citations

2.

Kelley, Mark R., James H. Wikel, Chunlu Guo, et al.. (2016). Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy. Journal of Pharmacology and Experimental Therapeutics. 359(2). 300–309. 51 indexed citations

3.

Crumb, William, Sean Ekins, R. Dustan Sarazan, et al.. (2006). Effects of Antipsychotic Drugs on Ito, INa, Isus, IK1, and hERG: QT Prolongation, Structure Activity Relationship, and Network Analysis. Pharmaceutical Research. 23(6). 1133–1143. 70 indexed citations

4.

Bednarczyk, Dallas, Sean Ekins, James H. Wikel, & Stephen H. Wright. (2003). Influence of Molecular Structure on Substrate Binding to the Human Organic Cation Transporter, hOCT1. Molecular Pharmacology. 63(3). 489–498. 86 indexed citations

5.

Ekins, Sean, William Crumb, R. Dustan Sarazan, James H. Wikel, & Steven Wrighton. (2002). Three-Dimensional Quantitative Structure-Activity Relationship for Inhibition of Human Ether-a-Go-Go-Related Gene Potassium Channel. Journal of Pharmacology and Experimental Therapeutics. 301(2). 427–434. 211 indexed citations

6.

Ekins, Sean, Richard B. Kim, Brenda F. Leake, et al.. (2002). Three-Dimensional Quantitative Structure-Activity Relationships of Inhibitors of P-Glycoprotein. Molecular Pharmacology. 61(5). 964–973. 138 indexed citations

7.

Ekins, Sean, Richard B. Kim, Brenda F. Leake, et al.. (2002). Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates. Molecular Pharmacology. 61(5). 974–981. 30 indexed citations

8.

Ekins, Sean, Richard B. Kim, Brenda F. Leake, et al.. (2002). Three-Dimensional Quantitative Structure-Activity Relationships of Inhibitors of P-Glycoprotein. Molecular Pharmacology. 61(5). 964–973. 16 indexed citations

9.

Ekins, Sean, Richard B. Kim, Brenda F. Leake, et al.. (2002). Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates. Molecular Pharmacology. 61(5). 974–981. 155 indexed citations

10.

Ekins, Sean, Gregory L. Durst, Robert E. Stratford, et al.. (2001). Three-Dimensional Quantitative Structure-Permeability Relationship Analysis for a Series of Inhibitors of Rhinovirus Replication. Journal of Chemical Information and Computer Sciences. 41(6). 1578–1586. 31 indexed citations

11.

Bravi, Gianpaolo & James H. Wikel. (2000). Application of MS-WHIM Descriptors: 3. Prediction of Molecular Properties. Quantitative Structure-Activity Relationships. 19(1). 39–49. 12 indexed citations

12.

Ekins, Sean, Chris L. Waller, Peter W. Swaan, et al.. (2000). Progress in predicting human ADME parameters in silico. Journal of Pharmacological and Toxicological Methods. 44(1). 251–272. 207 indexed citations

13.

Chirgadze, Nickolay Y., et al.. (1999). Diamino benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 3. Enhancing activity by imposing conformational restriction in the C-4″ side chain1. Bioorganic & Medicinal Chemistry Letters. 9(3). 363–368. 4 indexed citations

14.

Ekins, Sean, Gianpaolo Bravi, James H. Wikel, & Steven Wrighton. (1999). Three-Dimensional-Quantitative Structure Activity Relationship Analysis of Cytochrome P-450 3A4 Substrates. Journal of Pharmacology and Experimental Therapeutics. 291(1). 424–433. 104 indexed citations

15.

Ekins, Sean, Gianpaolo Bravi, Jennifer S. Gillespie, et al.. (1999). Three- and Four-Dimensional Quantitative Structure Activity Relationship Analyses of Cytochrome P-450 3A4 Inhibitors. Journal of Pharmacology and Experimental Therapeutics. 290(1). 429–438. 111 indexed citations

16.

Sall, Daniel J., Steve Briggs, Nickolay Y. Chirgadze, et al.. (1998). Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors. 2. Exploring interactions at the proximal (S2) binding site. Bioorganic & Medicinal Chemistry Letters. 8(18). 2527–2532. 8 indexed citations

17.

Sall, Daniel J., Ann Arfsten, Jefferson R. McCowan, et al.. (1997). Use of Conformationally Restricted Benzamidines as Arginine Surrogates in the Design of Platelet GPIIb-IIIa Receptor Antagonists. Journal of Medicinal Chemistry. 40(18). 2843–2857. 15 indexed citations

18.

McQuaid, Loretta A., Edward C. Smith, David Lodge, et al.. (1992). 3-Phenyl-4-hydroxyquinolin-2(1H)-ones: potent and selective antagonists at the strychnine-insensitive glycine site on the N-methyl-D-aspartate receptor complex. Journal of Medicinal Chemistry. 35(18). 3423–3425. 59 indexed citations

19.

Wikel, James H. & Charles J. Paget. (1975). ChemInform Abstract: SYNTHESIS OF S‐TRIAZOLO(3,4‐B)BENZOTHIAZOLES. Chemischer Informationsdienst. 6(10). 4 indexed citations

20.

Wikel, James H., et al.. (1971). The stevens rearrangement in aminimides. Tetrahedron Letters. 12(37). 3479–3482. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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