James H. Wikel

2.5k citations

38 papers · 1.8k indexed · h-index 19

Molecular Biology top 10%
Computational Theory and Mathematics top 0.5%
Pharmacology top 0.5%
Oncology top 5%
Spectroscopy top 5%

Co-authors: Sean Ekins Steven Wrighton Gianpaolo Bravi R. Dustan Sarazan William Crumb Jennifer S. Gillespie Barbara J. Ring Peter W. Swaan
Topics: Computational Drug Discovery Methods (13 papers)Drug Transport and Resistance Mechanisms (7 papers)Analytical Chemistry and Chromatography (6 papers)
Cited by: Pharmacology Computational Theory and Mathematics Spectroscopy
Journals: Journal of Medicinal Chemistry Journal of Pharmacology and Experimental Therapeutics The Journal of Organic Chemistry
Partner nations: United States Denmark

In The Last Decade

James H. Wikel

38 papers receiving 1.8k citations

Peers

Countries citing papers authored by James H. Wikel

Since Specialization

Citations

This map shows the geographic impact of James H. Wikel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James H. Wikel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James H. Wikel more than expected).

Fields of papers citing papers by James H. Wikel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James H. Wikel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James H. Wikel. The network helps show where James H. Wikel may publish in the future.

Co-authorship network of co-authors of James H. Wikel

This figure shows the co-authorship network connecting the top 25 collaborators of James H. Wikel. A scholar is included among the top collaborators of James H. Wikel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James H. Wikel. James H. Wikel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Ref-1/APE1 Inhibition with Novel Small Molecules Blocks Ocular Neovascularization 2018 ·PubMed Central ·Sheik Pran Babu Sardar Pasha,Kamakshi Sishtla,Rania S. Sulaiman,(unknown),(unknown),Fenil Shah,Melissa L. Fishel,James H. Wikel,Mark R. Kelley,Timothy W. Corson	38
2	Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy 2016 ·Journal of Pharmacology and Experimental Therapeutics ·Mark R. Kelley,James H. Wikel,Chunlu Guo,Karen E. Pollok,Barbara J. Bailey,(unknown),Melissa L. Fishel,Michael R. Vasko	51
3	Effects of Antipsychotic Drugs on Ito, INa, Isus, IK1, and hERG: QT Prolongation, Structure Activity Relationship, and Network Analysis 2006 ·Pharmaceutical Research ·William Crumb,Sean Ekins,R. Dustan Sarazan,James H. Wikel,Steven Wrighton,Christopher Carlson,Charles M. Beasley	70
4	Influence of Molecular Structure on Substrate Binding to the Human Organic Cation Transporter, hOCT1 2003 ·Molecular Pharmacology ·Dallas Bednarczyk,Sean Ekins,James H. Wikel,Stephen H. Wright	86
5	Three-Dimensional Quantitative Structure-Activity Relationship for Inhibition of Human Ether-a-Go-Go-Related Gene Potassium Channel 2002 ·Journal of Pharmacology and Experimental Therapeutics ·Sean Ekins,William Crumb,R. Dustan Sarazan,James H. Wikel,Steven Wrighton	211
6	Three-Dimensional Quantitative Structure-Activity Relationships of Inhibitors of P-Glycoprotein 2002 ·Molecular Pharmacology ·Sean Ekins,Richard B. Kim,Brenda F. Leake,Anne H. Dantzig,Erin G. Schuetz,Lu-Bin Lan,Kazuto Yasuda,Robert L. Shepard,Mark A. Winter,John D. Schuetz,James H. Wikel,Steven Wrighton	138
7	Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates 2002 ·Molecular Pharmacology ·Sean Ekins,Richard B. Kim,Brenda F. Leake,Anne H. Dantzig,Erin G. Schuetz,Lu-Bin Lan,Kazuto Yasuda,Robert L. Shepard,Mark A. Winter,John D. Schuetz,James H. Wikel,Steven Wrighton	30
8	Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates 2002 ·Molecular Pharmacology ·Sean Ekins,Richard B. Kim,Brenda F. Leake,Anne H. Dantzig,Erin G. Schuetz,Lu-Bin Lan,Kazuto Yasuda,Robert L. Shepard,Mark A. Winter,John D. Schuetz,James H. Wikel,Steven Wrighton	155
9	Three-Dimensional Quantitative Structure-Permeability Relationship Analysis for a Series of Inhibitors of Rhinovirus Replication 2001 ·Journal of Chemical Information and Computer Sciences ·Sean Ekins,Gregory L. Durst,Robert E. Stratford,David A. Thorner,Richard A. Lewis,Richard J. Loncharich,James H. Wikel	31
10	Progress in predicting human ADME parameters in silico 2000 ·Journal of Pharmacological and Toxicological Methods ·Sean Ekins,Chris L. Waller,Peter W. Swaan,Gabriele Cruciani,Steven Wrighton,James H. Wikel	207
11	Application of MS-WHIM Descriptors: 3. Prediction of Molecular Properties 2000 ·Quantitative Structure-Activity Relationships ·Gianpaolo Bravi,James H. Wikel	12
12	Diamino benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 3. Enhancing activity by imposing conformational restriction in the C-4″ side chain1 1999 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Nickolay Y. Chirgadze,(unknown),Donetta S. Gifford‐Moore,Daniel J. Sall,Gerald F. Smith,James H. Wikel	4
13	Three-Dimensional-Quantitative Structure Activity Relationship Analysis of Cytochrome P-450 3A4 Substrates 1999 ·Journal of Pharmacology and Experimental Therapeutics ·Sean Ekins,Gianpaolo Bravi,James H. Wikel,Steven Wrighton	104
14	Three- and Four-Dimensional Quantitative Structure Activity Relationship Analyses of Cytochrome P-450 3A4 Inhibitors 1999 ·Journal of Pharmacology and Experimental Therapeutics ·Sean Ekins,Gianpaolo Bravi,(unknown),Jennifer S. Gillespie,Barbara J. Ring,James H. Wikel,Steven Wrighton	111
15	Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors. 2. Exploring interactions at the proximal (S2) binding site 1998 ·Bioorganic & Medicinal Chemistry Letters ·Daniel J. Sall,Steve Briggs,Nickolay Y. Chirgadze,David K. Clawson,Donetta S. Gifford‐Moore,Valentine J. Klimkowski,Jefferson R. McCowan,Gerald F. Smith,James H. Wikel	8
16	Use of Conformationally Restricted Benzamidines as Arginine Surrogates in the Design of Platelet GPIIb-IIIa Receptor Antagonists 1997 ·Journal of Medicinal Chemistry ·Daniel J. Sall,Ann Arfsten,(unknown),(unknown),(unknown),Jefferson R. McCowan,J. M. JUN. MORIN,Jack W. Rose,Robert M. Scarborough,Mark S. Smyth,Suzane L. Um,Barbara G. Utterback,(unknown),James H. Wikel,Virginia L. Wyss,Joseph A. Jakubowski	15
17	3-Phenyl-4-hydroxyquinolin-2(1H)-ones: potent and selective antagonists at the strychnine-insensitive glycine site on the N-methyl-D-aspartate receptor complex 1992 ·Journal of Medicinal Chemistry ·Loretta A. McQuaid,Edward C. Smith,David Lodge,Étienne Pralong,James H. Wikel,David O. Calligaro,Patrick J. O’Malley	59
18	LY249933 1989 ·Journal of Cardiovascular Pharmacology ·(unknown),James H. Wikel,Raymond F. Kauffman,Jeffrey K. Smallwood,Karen M. Zimmerman,Barbara G. Utterback,(unknown),(unknown)	7
19	ChemInform Abstract: SYNTHESIS OF S‐TRIAZOLO(3,4‐B)BENZOTHIAZOLES 1975 ·Chemischer Informationsdienst ·James H. Wikel,Charles J. Paget	4
20	The stevens rearrangement in aminimides 1971 ·Tetrahedron Letters ·(unknown),James H. Wikel	9

About James H. Wikel

James H. Wikel is a scholar working on Computational Theory and Mathematics, Pharmacology and Organic Chemistry, having authored 38 papers that have together received 1.8k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (13 papers), Drug Transport and Resistance Mechanisms (7 papers) and Analytical Chemistry and Chromatography (6 papers). The work is most often cited by research in Pharmacology (532 citations), Computational Theory and Mathematics (730 citations) and Spectroscopy (317 citations). James H. Wikel has collaborated with scholars based in United States and Denmark. Frequent co-authors include Sean Ekins, Steven Wrighton, Gianpaolo Bravi, R. Dustan Sarazan, William Crumb, Jennifer S. Gillespie, Barbara J. Ring, Peter W. Swaan, Gabriele Cruciani and Chris L. Waller. Their work appears in journals such as Journal of Medicinal Chemistry, Journal of Pharmacology and Experimental Therapeutics and The Journal of Organic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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