Tyler Risom

3.4k citations

22 papers · 880 indexed · 1 hit paper · h-index 13

Impact in

Cancer Research top 10%
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Cancer Genomics and Diagnostics
Biophysics top 5%
- Cell Image Analysis Techniques

Papers in ⓘ

Modeling and Simulation 2
Oncology 11
- Cancer Cells and Metastasis 5
- HER2/EGFR in Cancer Research 2

Co-authors: William M. Strauss (2 shared papers)Michael Angelo (4 shared papers)Leeat Keren (2 shared papers)Erin McCaffrey (2 shared papers)Marc Bossé (2 shared papers)Kausalia Vijayaragavan (2 shared papers)Noah F. Greenwald (2 shared papers)Sean C. Bendall (2 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (7 papers)Science Advances (1 paper)Journal of Clinical Investigation (1 paper)DNA and Cell Biology (1 paper)Neuro-Oncology Advances (1 paper)
Partner nations: United States United Kingdom Israel

In The Last Decade

Tyler Risom

19 papers receiving 866 citations

Hit Papers

align trajectories log scale

MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure 2019 · 267 citations

Peers

Countries citing papers authored by Tyler Risom

Since Specialization

Citations

This map shows the geographic impact of Tyler Risom's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tyler Risom with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tyler Risom more than expected).

Fields of papers citing papers by Tyler Risom

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tyler Risom. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tyler Risom. The network helps show where Tyler Risom may publish in the future.

Co-authors

The 25 scholars most cited alongside Tyler Risom, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Tyler Risom Line = papers co-authored together Tyler Risom links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 22 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure Science Advances ·Leeat Keren, Marc Bossé, Sarah-Anne Thompson, Tyler Risom, Kausalia Vijayaragavan, Erin McCaffrey, Diana M. Marquez, Roshan Angoshtari, Noah F. Greenwald, Harris G. Fienberg, Jennifer Wang, Neeraja Kambham, David H. Kirkwood, Garry P. Nolan, Thomas J. Montine, Stephen J. Galli, Robert B. West, Sean C. Bendall, Michael Angelo Hit paper breakdown →	2019	267
2	Evolutionary Conservation of MicroRNA Regulatory Circuits: An Examination of MicroRNA Gene Complexity and Conserved MicroRNA-Target Interactions through Metazoan Phylogeny DNA and Cell Biology ·Chung-Tien Lee, Tyler Risom, William M. Strauss	2007	180
3	Activation of PP2A and Inhibition of mTOR Synergistically Reduce MYC Signaling and Decrease Tumor Growth in Pancreatic Ductal Adenocarcinoma Cancer Research ·Brittany L. Allen-Petersen, Tyler Risom, Zipei Feng, Zhiping Wang, Zina P. Jenny, Mary C. Thoma, Katherine R. Pelz, Jennifer P. Morton, Owen J. Sansom, Charles D. Lopez, Brett C. Sheppard, Dale J. Christensen, Michael Ohlmeyer, Goutham Narla, Rosalie C. Sears	2018	62
4	MicroRNAs in mammalian development Birth Defects Research Part C Embryo Today Reviews ·Chung-Tien Lee, Tyler Risom, William M. Strauss	2006	57
5	Pyrazolopyridine inhibitors of B-RafV600E. Part 2: Structure–activity relationships Bioorganic & Medicinal Chemistry Letters ·Steve Wenglowsky, Kateri A. Ahrendt, Alex J. Buckmelter, Bainian Feng, Susan L. Gloor, Stefan Gradl, Jonas Grina, Joshua D. Hansen, Ellen R. Laird, Paul J. Lunghofer, Simon Mathieu, David Moreno‐Mateos, Brad Newhouse, Li Ren, Tyler Risom, Joachim Rudolph, Jeongbeob Seo, Hillary L. Sturgis, W.C. Voegtli, Zhaoyang Wen	2011	50
6	Discovery of pyrrolopyrimidine inhibitors of Akt Bioorganic & Medicinal Chemistry Letters ·James F. Blake, Nicholas C. Kallan, Dengming Xiao, Rui Xu, Josef R. Bencsik, Nicholas J. Skelton, Keith L. Spencer, Ian S. Mitchell, Richard Woessner, Susan L. Gloor, Tyler Risom, Stefan Groß, Matthew Martinson, Tony Morales, Guy Vigers, Barbara J. Brandhuber	2010	46
7	Discovery and SAR of spirochromane Akt inhibitors Bioorganic & Medicinal Chemistry Letters ·Nicholas C. Kallan, Keith L. Spencer, James F. Blake, Rui Xu, Justin Heizer, Josef R. Bencsik, Ian S. Mitchell, Susan L. Gloor, Matthew Martinson, Tyler Risom, Stefan Groß, Tony Morales, Wen‐I Wu, Guy Vigers, Barbara J. Brandhuber, Nicholas J. Skelton	2011	33
8	Deregulating MYC in a model of HER2+ breast cancer mimics human intertumoral heterogeneity Journal of Clinical Investigation ·Tyler Risom, Xiaoyan Wang, Juan Liang, Xiaoli Zhang, Carl Pelz, Lydia G. Campbell, Jenny Eng, Koei Chin, Caroline Farrington, Goutham Narla, Ellen M. Langer, Xiao‐Xin Sun, Yulong Su, Colin J. Daniel, Mu‐Shui Dai, Christiane V. Löhr, Rosalie C. Sears	2019	31
9	Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer Communications Biology ·Aalok Patwa, Rikiya Yamashita, Jin Long, Tyler Risom, Michael Angelo, Leeat Keren, Daniel L. Rubin	2021	29
10	Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors Bioorganic & Medicinal Chemistry Letters ·Josef R. Bencsik, Dengming Xiao, James F. Blake, Nicholas C. Kallan, Ian S. Mitchell, Keith L. Spencer, Rui Xu, Susan L. Gloor, Matthew Martinson, Tyler Risom, Richard Woessner, Faith P. Dizon, Wen‐I Wu, Guy Vigers, Barbara J. Brandhuber, Nicholas J. Skelton, Wei Wei Prior, Lesley Murray	2010	29
11	Pyrazolopyridine inhibitors of B-RafV600E. Part 4: Rational design and kinase selectivity profile of cell potent type II inhibitors Bioorganic & Medicinal Chemistry Letters ·Steve Wenglowsky, David Moreno‐Mateos, Ellen R. Laird, Susan L. Gloor, Li Ren, Tyler Risom, Joachim Rudolph, Hillary L. Sturgis, W.C. Voegtli	2012	27
12	Multiplexed Ion Beam Imaging: Insights into Pathobiology Annual Review of Pathology Mechanisms of Disease ·Candace C. Liu, Erin McCaffrey, Noah F. Greenwald, Erin Soon, Tyler Risom, Kausalia Vijayaragavan, John-Paul Oliveria, Dunja Mrdjen, Marc Bossé, Dmitry Tebaykin, Sean C. Bendall, Michael Angelo	2021	17
13	The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase Bioorganic & Medicinal Chemistry Letters ·Li Ren, Kateri A. Ahrendt, Jonas Grina, Ellen R. Laird, Alex J. Buckmelter, Joshua D. Hansen, Brad Newhouse, David Moreno‐Mateos, Steve Wenglowsky, Victoria Dinkel, Susan L. Gloor, Gregg Hastings, Sumeet Rana, Kevin Rasor, Tyler Risom, Hillary L. Sturgis, W.C. Voegtli, Simon Mathieu	2012	14
14	Modeling differentiation-state transitions linked to therapeutic escape in triple-negative breast cancer PLoS Computational Biology ·Margaret P. Chapman, Tyler Risom, Anil Aswani, Ellen M. Langer, Rosalie C. Sears, Claire J. Tomlin	2019	12
15	Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA Bioorganic & Medicinal Chemistry Letters ·Rui Xu, Anna L. Banka, James F. Blake, Ian S. Mitchell, Eli M. Wallace, Josef R. Bencsik, Nicholas C. Kallan, Keith L. Spencer, Susan L. Gloor, Matthew Martinson, Tyler Risom, Stefan Groß, Tony Morales, Wen‐I Wu, Guy Vigers, Barbara J. Brandhuber, Nicholas J. Skelton	2011	10
16	A model of phenotypic state dynamics initiates a promising approach to control heterogeneous malignant cell populations Margaret P. Chapman, Tyler Risom, Anil Aswani, Roel Dobbe, Rosalie C. Sears, Claire J. Tomlin	2016	6
17	Transcriptional signatures in histologic structures within glioblastoma tumors may predict personalized drug sensitivity and survival Neuro-Oncology Advances ·Cymon Kersch, Cheryl Claunch, Prakash Ambady, Elmar Bucher, Daniel L. Schwartz, Ramon Barajas, Jeffrey J. Iliff, Tyler Risom, Laura M. Heiser, Leslie L. Muldoon, James E. Korkola, Joe W. Gray, Edward A. Neuwelt	2020	4
18	Highly multiplexed imaging reveals prognostic immune and stromal spatial biomarkers in breast cancer JCI Insight ·Jennifer Eng, Elmar Bucher, Zhiwei Hu, Cameron R. Walker, Tyler Risom, Michael Angelo, Paula I. González-Ericsson, Melinda E. Sanders, A. Bapsi Chakravarthy, Jennifer A. Pietenpol, Summer L. Gibbs, Rosalie C. Sears, Koei Chin	2025	3
19	Mass Spectrometry-Based Tissue Imaging of the Tumor Microenvironment Methods in molecular biology ·Tyler Risom, Patrick Chang, Sandra Rost, James Ziai	2023	2
20	Abstract B51: Modeling the intrinsic and extrinsic influences on breast cancer phenotypic heterogeneity using mouse models and three-dimensional bioprinting Molecular Cancer Research ·Ellen M. Langer, Xiaoyan Wang, Juan Liang, Brittany L. Allen-Petersen, Nicholas D. Kendsersky, Tyler Risom, Carl Pelz, Rosalie C. Sears	2016	1

About Tyler Risom

Tyler Risom is a scholar working on Modeling and Simulation, Oncology, Cancer Research, Molecular Biology and Genetics, having authored 22 papers that have together received 880 indexed citations. Recurring topics across this work include PI3K/AKT/mTOR signaling in cancer (7 papers), Cancer Cells and Metastasis (5 papers), Protein Kinase Regulation and GTPase Signaling (5 papers), Single-cell and spatial transcriptomics (3 papers), Melanoma and MAPK Pathways (3 papers), Cancer Mechanisms and Therapy (3 papers), MicroRNA in disease regulation (2 papers) and HER2/EGFR in Cancer Research (2 papers). The work is most often cited by research in Cancer Research (264 citations), Biophysics (73 citations), Molecular Biology (629 citations), Oncology (128 citations) and Organic Chemistry (115 citations). Tyler Risom has collaborated with scholars based in United States, United Kingdom and Israel. Frequent co-authors include William M. Strauss, Michael Angelo, Leeat Keren, Erin McCaffrey, Marc Bossé, Kausalia Vijayaragavan, Noah F. Greenwald, Sean C. Bendall, David H. Kirkwood and Harris G. Fienberg. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Science Advances, Journal of Clinical Investigation, DNA and Cell Biology and Neuro-Oncology Advances.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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