Dave Boucher

3.8k total citations · 3 hit papers
29 papers, 2.9k citations indexed

About

Dave Boucher is a scholar working on Molecular Biology, Immunology and Surgery. According to data from OpenAlex, Dave Boucher has authored 29 papers receiving a total of 2.9k indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Molecular Biology, 15 papers in Immunology and 6 papers in Surgery. Recurrent topics in Dave Boucher's work include Inflammasome and immune disorders (23 papers), Cell death mechanisms and regulation (10 papers) and interferon and immune responses (7 papers). Dave Boucher is often cited by papers focused on Inflammasome and immune disorders (23 papers), Cell death mechanisms and regulation (10 papers) and interferon and immune responses (7 papers). Dave Boucher collaborates with scholars based in Australia, United Kingdom and Switzerland. Dave Boucher's co-authors include Kate Schroder, Kaiwen Chen, Mercedes Monteleone, Rebecca C. Coll, Jessica B. von Pein, Avril A. B. Robertson, Petr Brož, Damiën Bierschenk, Matthew J. Sweet and Connie M. Ross and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Dave Boucher

28 papers receiving 2.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition

2019 704 citations Rebecca C. Coll, James R. Hill et al. Nature Chemical Biology profile →
Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps

2018 484 citations Kaiwen Chen, Mercedes Monteleone et al. profile →
Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

2018 439 citations Dave Boucher, Mercedes Monteleone et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Dave Boucher Australia	17	2.5k	1.3k	376	275	244	29	2.9k
Sebastian Rühl Switzerland	9	2.4k 1.0×	1.1k 0.9×	411 1.1×	238 0.9×	237 1.0×	11	2.7k
Rosalie Heilig Switzerland	13	2.6k 1.1×	1.2k 1.0×	433 1.2×	214 0.8×	293 1.2×	14	3.0k
Lichen Hu China	5	2.3k 0.9×	897 0.7×	454 1.2×	210 0.8×	230 0.9×	6	2.6k
Pengda Chen China	6	2.3k 0.9×	926 0.7×	339 0.9×	179 0.7×	181 0.7×	9	2.7k
Salina Louie United States	9	2.3k 0.9×	1.2k 0.9×	281 0.7×	243 0.9×	187 0.8×	14	2.7k
Stéphanie Papin Switzerland	16	1.8k 0.7×	1.0k 0.8×	256 0.7×	240 0.9×	135 0.6×	25	2.2k
Laetitia Agostini Switzerland	5	2.2k 0.9×	1.5k 1.2×	248 0.7×	298 1.1×	147 0.6×	5	2.7k
Alessandra Pontillo Brazil	29	1.7k 0.7×	1.2k 0.9×	172 0.5×	266 1.0×	140 0.6×	91	2.5k
Irma B. Stowe United States	9	1.5k 0.6×	861 0.7×	231 0.6×	180 0.7×	156 0.6×	9	1.9k
David E. Place United States	20	2.4k 1.0×	1.4k 1.1×	219 0.6×	203 0.7×	203 0.8×	35	3.2k

Countries citing papers authored by Dave Boucher

Since Specialization

Citations

This map shows the geographic impact of Dave Boucher's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dave Boucher with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dave Boucher more than expected).

Fields of papers citing papers by Dave Boucher

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dave Boucher. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dave Boucher. The network helps show where Dave Boucher may publish in the future.

Co-authorship network of co-authors of Dave Boucher

This figure shows the co-authorship network connecting the top 25 collaborators of Dave Boucher. A scholar is included among the top collaborators of Dave Boucher based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Dave Boucher. Dave Boucher is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Reis, Luiza Campos, José Ângelo Lauletta Lindoso, Sally James, et al.. (2025). IL-32–producing CD8+ memory T cells define immunoregulatory niches in human cutaneous leishmaniasis. Journal of Clinical Investigation. 135(10). 1 indexed citations

Grant, Sarah Schmidt & Dave Boucher. (2025). 10 things you wish you knew about inflammatory caspases: A holistic review of their biochemistry, activation, and signalling. Journal of Biological Chemistry. 301(10). 110557–110557.

Coombs, J., Alina Zamoshnikova, Caroline L. Holley, et al.. (2024). NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome. Science Signaling. 17(820). eabg8145–eabg8145. 19 indexed citations

Thygesen, Sara J, Sabrina Sofia Burgener, Mercedes Monteleone, et al.. (2024). Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages. European Journal of Immunology. 54(5). e2350515–e2350515. 1 indexed citations

Robinson, Kim S. & Dave Boucher. (2024). Inflammasomes in epithelial innate immunity: front line warriors. FEBS Letters. 598(11). 1335–1353. 2 indexed citations

Ravikumar, Sharada, Wei Leong Chew, Qi Hui Sam, et al.. (2023). Extracorporeal Membrane Oxygenation–Dependent Fulminant Melioidosis From Caspase 4 Mutation Reversed by Interferon Gamma Therapy. Clinical Infectious Diseases. 78(1). 94–97. 5 indexed citations

Chan, Amy H., Sabrina Sofia Burgener, Xiaohui Wang, et al.. (2023). Caspase-4 dimerisation and D289 auto-processing elicit an interleukin-1β-converting enzyme. Life Science Alliance. 6(10). e202301908–e202301908. 19 indexed citations

Monteleone, Mercedes & Dave Boucher. (2022). Measuring Non-canonical Inflammasome Activation in Neutrophils. Methods in molecular biology. 2459. 29–37. 1 indexed citations

Bezbradica, Jelena S., Rebecca C. Coll, & Dave Boucher. (2022). Activation of the Non-canonical Inflammasome in Mouse and Human Cells. Methods in molecular biology. 2459. 51–63. 4 indexed citations

10.

Boucher, Dave, et al.. (2022). Gasdermin D Cleavage Assay Following Inflammasome Activation. Methods in molecular biology. 2459. 39–49. 7 indexed citations

11.

Santos, José Carlos, Dave Boucher, Larisa E. Kapinos, et al.. (2020). Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria. Nature Communications. 11(1). 3276–3276. 190 indexed citations

12.

Heilig, Rosalie, Marisa Dilucca, Dave Boucher, et al.. (2020). Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD. Life Science Alliance. 3(6). e202000735–e202000735. 81 indexed citations

13.

Murthy, Ambika M. V., Matthew J. Sullivan, Nguyen Thi Khanh Nhu, et al.. (2019). Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3‐dependent vs . ‐independent macrophage cell death and host colonization. The FASEB Journal. 33(6). 7437–7450. 15 indexed citations

14.

Coll, Rebecca C., James R. Hill, Christopher J. Day, et al.. (2019). MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition. Nature Chemical Biology. 15(6). 556–559. 704 indexed citations breakdown →

15.

Boucher, Dave, Amy H. Chan, Connie M. Ross, & Kate Schroder. (2018). Quantifying Caspase-1 Activity in Murine Macrophages. Methods in molecular biology. 1725. 163–176. 10 indexed citations

16.

Chen, Kaiwen, Kate E. Lawlor, Jessica B. von Pein, et al.. (2018). Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion. The Journal of Immunology. 200(10). 3341–3346. 26 indexed citations

17.

Monteleone, Mercedes, Amanda C. Stanley, Kaiwen Chen, et al.. (2018). Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion. Cell Reports. 24(6). 1425–1433. 243 indexed citations

18.

Bierschenk, Damiën, Dave Boucher, & Kate Schroder. (2016). Salmonella-induced inflammasome activation in humans. Molecular Immunology. 86. 38–43. 30 indexed citations

19.

Boucher, Dave, Catherine Duclos, & Jean‐Bernard Denault. (2014). General In Vitro Caspase Assay Procedures. Methods in molecular biology. 1133. 3–39. 18 indexed citations

20.

Boucher, Dave, Véronique Blais, Marcin Drąg, & Jean‐Bernard Denault. (2010). Molecular determinants involved in activation of caspase 7. Bioscience Reports. 31(4). 283–294. 19 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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