Jaap Brouwer

2.2k citations

59 papers · 1.9k · h-index 26

Impact in

Molecular Biology top 5%
- DNA Repair Mechanisms
- Genomics and Chromatin Dynamics
- CRISPR and Genetic Engineering
- DNA and Nucleic Acid Chemistry
- Ubiquitin and proteasome pathways
- RNA Research and Splicing
Physiology top 5%

Papers in

Molecular Biology 44
- DNA Repair Mechanisms 22
- DNA and Nucleic Acid Chemistry 11
- Genomics and Chromatin Dynamics 9
- Fungal and yeast genetics research 8
- Receptor Mechanisms and Signaling 5
- CRISPR and Genetic Engineering 5
Oncology 17
- Metal complexes synthesis and properties 16

Co-authors: J. Reedijk (17 shared papers)Richard A. Verhage (9 shared papers)Hans den Dulk (23 shared papers)Pieter van de Putte (9 shared papers)Bart Jansen (7 shared papers)Lars E.T. Jansen (2 shared papers)Marcel Tijsterman (5 shared papers)Dang Duong Bang (3 shared papers)
Journals: Journal of Inorganic Biochemistry (4 papers)Molecular Pharmacology (4 papers)Molecular and Cellular Biology (4 papers)DNA repair (3 papers)European Journal of Inorganic Chemistry (3 papers)
Partner nations: Netherlands United States United Kingdom

In The Last Decade

Jaap Brouwer

59 papers receiving 1.9k citations

Peers

Countries citing papers authored by Jaap Brouwer

Since Specialization

Citations

This map shows the geographic impact of Jaap Brouwer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jaap Brouwer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jaap Brouwer more than expected).

Fields of papers citing papers by Jaap Brouwer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jaap Brouwer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jaap Brouwer. The network helps show where Jaap Brouwer may publish in the future.

Co-authors

The 25 scholars most cited alongside Jaap Brouwer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jaap Brouwer Line = papers co-authored together Jaap Brouwer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 59 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A Rad26–Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage Nature ·E C Woudstra, Chris Gilbert, Jane Fellows, Lars E.T. Jansen, Jaap Brouwer, Hediye Erdjument‐Bromage, Paul Tempst, Jesper Q. Svejstrup	2002	188
2	Glutathione induces cellular resistance against cationic dinuclear platinum anticancer drugs Journal of Inorganic Biochemistry ·Bart Jansen, Jaap Brouwer, J. Reedijk	2002	116
3	Molecular cloning of RAD16, a gene involved in differential repair inSaccharomyces cerevisiae Nucleic Acids Research ·Dang Duong Bang, Richard A. Verhage, Nora Goosen, Jaap Brouwer, P. van de Putte	1992	96
4	Double Mutants of Saccharomyces cerevisiae with Alterations in Global Genome and Transcription-Coupled Repair Molecular and Cellular Biology ·Richard A. Verhage, Alain J. van Gool, Nanda de Groot, Jan H.J. Hoeijmakers, Pieter van de Putte, Jaap Brouwer	1996	85
5	Activity-Based Profiling Reveals Reactivity of the Murine Thymoproteasome-Specific Subunit β5t Chemistry & Biology ·Bogdan I. Florea, Martijn Verdoes, Nan Li, Wouter A. van der Linden, Paul P. Geurink, Hans van den Elst, Tanja Hofmann, Arnoud de Ru, Peter A. van Veelen, Keiji Tanaka, Katsuhiro Sasaki, Shigeo Murata, Hans den Dulk, Jaap Brouwer, Ferry Ossendorp, Alexei F. Kisselev, Herman S. Overkleeft	2010	70
6	Preferential Binding of Yeast Rad4·Rad23 Complex to Damaged DNA Journal of Biological Chemistry ·Lars E.T. Jansen, Richard A. Verhage, Jaap Brouwer	1998	69
7	Development of an Activity‐Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase‐α in Brain Angewandte Chemie International Edition ·Marc P. Baggelaar, Freek J. Janssen, Annelot C. M. van Esbroeck, Hans den Dulk, Marco Allarà, Sascha Hoogendoorn, Ross McGuire, Bogdan I. Florea, Nico J. Meeuwenoord, Hans van den Elst, Gijsbert A. van der Marel, Jaap Brouwer, Vincenzo Di Marzo, Herman S. Overkleeft, Mario van der Stelt	2013	59
8	Why Are A_2BReceptors Low-Affinity Adenosine Receptors? Mutation of Asn273 to Tyr Increases Affinity of Human A_2BReceptor for 2-(1-Hexynyl)adenosine Molecular Pharmacology ·Margot W. Beukers, Hans den Dulk, Erica W. van Tilburg, Jaap Brouwer, Adriaan P. IJzerman	2000	59
9	The RAD7 and RAD16 Genes, Which Are Essential for Pyrimidine Dimer Removal from the Silent Mating Type Loci, Are Also Required for Repair of the Nontranscribed Strand of an Active Gene in Saccharomyces cerevisiae Molecular and Cellular Biology ·Richard A. Verhage, Anne‐Marie Zeeman, Nanda de Groot, Fiona Gleig, Dang Duong Bang, Pieter van de Putte, Jaap Brouwer	1994	56
10	⁶⁰Co γ-rays induce predominantly C/G to G/C transversions in double-stranded M13 DNA Nucleic Acids Research ·Barbara Hoebee, Jaap Brouwer, Pieter van de Putte, H. Loman, J. Retèl	1988	51
11	RNA Polymerase II Transcription Suppresses Nucleosomal Modulation of UV-Induced (6-4) Photoproduct and Cyclobutane Pyrimidine Dimer Repair in Yeast Molecular and Cellular Biology ·Marcel Tijsterman, Remko de Pril, Judith G. Tasseron-de Jong, Jaap Brouwer	1999	51
12	Dinuclear platinum complexes with N,N′-bis(aminoalkyl)-1,4-diaminoanthraquinones as linking ligands. Part I. Synthesis, cytotoxicity, and cellular studies in A2780 human ovarian carcinoma cells JBIC Journal of Biological Inorganic Chemistry ·Bart Jansen, Peter Wielaard, Ganna V. Kalayda, Marco Ferrari, Chris Molenaar, Hans J. Tanke, Jaap Brouwer, J. Reedijk	2004	49
13	New insights in DNA repair: preferential repair of transcriptionally active DNA Mutagenesis ·Carrol Terleth, Pieter van de Putte, Jaap Brouwer	1991	47
14	Transitions in the coupling of transcription and nucleotide excision repair within RNA polymerase II-transcribed genes of Saccharomyces cerevisiae Proceedings of the National Academy of Sciences ·Marcel Tijsterman, Richard A. Verhage, Pieter van de Putte, Judith G. Tasseron-de Jong, Jaap Brouwer	1997	46
15	Synthesis, Crystal Structure, Studies in Solution and Cytotoxicity of Two New Fluorescent Platinum(II) Compounds Containing Anthracene Derivatives as a Carrier Ligand Inorganic Chemistry ·Patricia Marqués‐Gallego, Hans den Dulk, Jaap Brouwer, H. Kooijman, Anthony L. Spek, Olivier Roubeau, Simon J. Teat, J. Reedijk	2008	46
16	Random Mutagenesis of the Human Adenosine A2B Receptor Followed by Growth Selection in Yeast. Identification of Constitutively Active and Gain of Function Mutations Molecular Pharmacology ·Margot W. Beukers, Joris van Oppenraaij, Patrick P.W. van der Hoorn, Clara C. Blad, Hans den Dulk, Jaap Brouwer, Adriaan P. IJzerman	2004	44
17	Dinuclear Alkyldiamine Platinum Antitumor Compounds: A Structure−Activity Relationship Study Journal of Medicinal Chemistry ·Bart Jansen, Judith van der Zwan, Hans den Dulk, Jaap Brouwer, J. Reedijk	2000	44
18	Anticancer Drug Resistance Induced by Disruption of the Saccharomyces cerevisiae NPR2 Gene: a Novel Component Involved in Cisplatin- and Doxorubicin-Provoked Cell Kill Molecular Pharmacology ·Paul W. Schenk, Mariël Brok, Antonius W.M. Boersma, Jourica A. Brandsma, Hans den Dulk, Herman Burger, G. Stoter, Jaap Brouwer, Kees Nooter	2003	42
19	A Tetranuclear Platinum Compound Designed to Overcome Cisplatin Resistance European Journal of Inorganic Chemistry ·Bart Jansen, Judith van der Zwan, J. Reedijk, Hans den Dulk, Jaap Brouwer	1999	42
20	A Genome-Wide Screening in Saccharomyces cerevisiae for Genes That Confer Resistance to the Anticancer Agent Cisplatin Biochemical and Biophysical Research Communications ·Herman Burger, Astrid Capello, Paul W. Schenk, G. Stoter, Jaap Brouwer, Kees Nooter	2000	37

About Jaap Brouwer

Jaap Brouwer is a scholar working on Molecular Biology, Oncology, Organic Chemistry, Plant Science and Physiology, having authored 59 papers that have together received 1.9k indexed citations. Recurring topics across this work include DNA Repair Mechanisms (22 papers), Metal complexes synthesis and properties (16 papers), Ferrocene Chemistry and Applications (11 papers), DNA and Nucleic Acid Chemistry (11 papers), Genomics and Chromatin Dynamics (9 papers), Fungal and yeast genetics research (8 papers), Receptor Mechanisms and Signaling (5 papers) and CRISPR and Genetic Engineering (5 papers). The work is most often cited by research in Molecular Biology (1.4k citations), Physiology (93 citations), Oncology (466 citations), Organic Chemistry (325 citations) and Cancer Research (162 citations). Jaap Brouwer has collaborated with scholars based in Netherlands, United States and United Kingdom. Frequent co-authors include J. Reedijk, Richard A. Verhage, Hans den Dulk, Pieter van de Putte, Bart Jansen, Lars E.T. Jansen, Marcel Tijsterman, Dang Duong Bang, Paul Tempst and Chris Gilbert. Their work appears in journals such as Journal of Inorganic Biochemistry, Molecular Pharmacology, Molecular and Cellular Biology, DNA repair and European Journal of Inorganic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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