Adriaan P. IJzerman

28.1k total citations · 5 hit papers
470 papers, 21.3k citations indexed

About

Adriaan P. IJzerman is a scholar working on Molecular Biology, Physiology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Adriaan P. IJzerman has authored 470 papers receiving a total of 21.3k indexed citations (citations by other indexed papers that have themselves been cited), including 373 papers in Molecular Biology, 228 papers in Physiology and 139 papers in Cellular and Molecular Neuroscience. Recurrent topics in Adriaan P. IJzerman's work include Receptor Mechanisms and Signaling (247 papers), Adenosine and Purinergic Signaling (228 papers) and Pharmacological Receptor Mechanisms and Effects (96 papers). Adriaan P. IJzerman is often cited by papers focused on Receptor Mechanisms and Signaling (247 papers), Adenosine and Purinergic Signaling (228 papers) and Pharmacological Receptor Mechanisms and Effects (96 papers). Adriaan P. IJzerman collaborates with scholars based in Netherlands, United States and United Kingdom. Adriaan P. IJzerman's co-authors include Kenneth A. Jacobson, Joel Linden, Bertil B. Fredholm, Laura H. Heitman, Karl‐Norbert Klotz, Raymond C. Stevens, Gerard J. P. van Westen, Christa E. Müller, Vadim Cherezov and J. Robert Lane and has published in prestigious journals such as Nature, Science and Chemical Reviews.

In The Last Decade

Adriaan P. IJzerman

466 papers receiving 20.7k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors

2001 2.2k citations Bertil B. Fredholm, Adriaan P. IJzerman et al. Pharmacological Reviews profile →
The 2.6 Angstrom Crystal Structure of a Human A _2A Adenosine Receptor Bound to an Antagonist

2008 1.5k citations Veli‐Pekka Jaakola, Mark T. Griffith et al. Science profile →
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update

2011 1.1k citations Bertil B. Fredholm, Adriaan P. IJzerman et al. Pharmacological Reviews profile →
Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

2012 777 citations Wei Liu, Eugene Chun et al. Science profile →
Small molecule absorption by PDMS in the context of drug response bioassays

2016 343 citations Henk de Vries, Adriaan P. IJzerman et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Adriaan P. IJzerman Netherlands	66	13.9k	7.8k	5.7k	3.1k	2.6k	470	21.3k
Martin J. Lohse Germany	91	22.2k 1.6×	2.4k 0.3×	10.9k 1.9×	851 0.3×	669 0.3×	355	29.4k
Vsevolod Katritch United States	57	15.0k 1.1×	1.3k 0.2×	8.0k 1.4×	896 0.3×	2.7k 1.0×	133	17.8k
Zhan‐Guo Gao United States	63	9.7k 0.7×	5.6k 0.7×	2.3k 0.4×	1.5k 0.5×	437 0.2×	259	16.7k
Pier Andrea Borea Italy	64	5.9k 0.4×	6.4k 0.8×	2.4k 0.4×	2.4k 0.8×	338 0.1×	341	13.1k
Rafael Franco Spain	83	11.8k 0.8×	6.4k 0.8×	9.7k 1.7×	567 0.2×	457 0.2×	479	22.9k
Stefano Moro Italy	56	7.4k 0.5×	2.2k 0.3×	957 0.2×	3.6k 1.2×	1.8k 0.7×	354	12.7k
Michael Spedding France	65	11.7k 0.8×	1.2k 0.2×	8.4k 1.5×	750 0.2×	902 0.3×	231	24.4k
Claudia Martini Italy	50	4.9k 0.3×	2.0k 0.3×	2.1k 0.4×	2.9k 0.9×	366 0.1×	526	11.3k
William H. Prusoff United States	40	10.8k 0.8×	893 0.1×	5.0k 0.9×	2.5k 0.8×	537 0.2×	191	16.6k
Yung-Chi Cheng United States	17	8.9k 0.6×	768 0.1×	5.0k 0.9×	1.4k 0.5×	505 0.2×	20	12.6k

Countries citing papers authored by Adriaan P. IJzerman

Since Specialization

Citations

This map shows the geographic impact of Adriaan P. IJzerman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Adriaan P. IJzerman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Adriaan P. IJzerman more than expected).

Fields of papers citing papers by Adriaan P. IJzerman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Adriaan P. IJzerman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Adriaan P. IJzerman. The network helps show where Adriaan P. IJzerman may publish in the future.

Co-authorship network of co-authors of Adriaan P. IJzerman

This figure shows the co-authorship network connecting the top 25 collaborators of Adriaan P. IJzerman. A scholar is included among the top collaborators of Adriaan P. IJzerman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Adriaan P. IJzerman. Adriaan P. IJzerman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Veldhoven, Jacobus P. D. van, Natalia V. Ortiz Zacarı́as, Jianhui Wang, et al.. (2024). Labeling of CC Chemokine Receptor 2 with a Versatile Intracellular Allosteric Probe. ACS Chemical Biology. 19(9). 2070–2080.

Liu, Rongfang, Gerard J. P. van Westen, Willem Jespers, et al.. (2024). N-Acyl-N-Alkyl Sulfonamide Probes for Ligand-Directed Covalent Labeling of GPCRs: The Adenosine A_2B Receptor as Case Study. ACS Chemical Biology. 19(7). 1554–1562. 3 indexed citations

González, Marina Gorostiola, et al.. (2024). Computational Characterization of Membrane Proteins as Anticancer Targets: Current Challenges and Opportunities. International Journal of Molecular Sciences. 25(7). 3698–3698. 1 indexed citations

Liu, Rongfang, Anton T. J. Tool, Sylvia E. Le Dévédec, et al.. (2023). Development of an Affinity-Based Probe to Profile Endogenous Human Adenosine A ₃ Receptor Expression . Journal of Medicinal Chemistry. 66(16). 11399–11413. 4 indexed citations

Liu, Xuhan, Kai Ye, Herman van Vlijmen, Adriaan P. IJzerman, & Gerard J. P. van Westen. (2023). DrugEx v3: scaffold-constrained drug design with graph transformer-based reinforcement learning. Journal of Cheminformatics. 15(1). 24–24. 45 indexed citations

Sydow, Dominique, Angelika Szengel, Herman van Vlijmen, et al.. (2019). Advances and Challenges in Computational Target Prediction. Journal of Chemical Information and Modeling. 59(5). 1728–1742. 77 indexed citations

Soethoudt, Marjolein, Sara Christina Stolze, Matthias V. Westphal, et al.. (2018). Selective Photoaffinity Probe That Enables Assessment of Cannabinoid CB₂ Receptor Expression and Ligand Engagement in Human Cells. Journal of the American Chemical Society. 140(19). 6067–6075. 71 indexed citations

Sala, Luca, Zhiyi Yu, Dorien Ward‐van Oostwaard, et al.. (2016). A new hERG allosteric modulator rescues genetic and drug‐induced long‐ QT syndrome phenotypes in cardiomyocytes from isogenic pairs of patient induced pluripotent stem cells. EMBO Molecular Medicine. 8(9). 1065–1081. 68 indexed citations

Nederpelt, Indira, et al.. (2016). Kinetic Profile of Neuropeptide–Receptor Interactions. Trends in Neurosciences. 39(12). 830–839. 8 indexed citations

10.

Liu, Wei, Eugene Chun, Aaron A. Thompson, et al.. (2012). Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions. Science. 337(6091). 232–236. 777 indexed citations breakdown →

11.

Bot, Ilze, Henk de Vries, Suzanne J.A. Korporaal, et al.. (2012). Adenosine A _2B Receptor Agonism Inhibits Neointimal Lesion Development After Arterial Injury in Apolipoprotein E–Deficient Mice. Arteriosclerosis Thrombosis and Vascular Biology. 32(9). 2197–2205. 22 indexed citations

12.

Horst, Eelke van der, et al.. (2011). Substructure‐Based Virtual Screening for Adenosine A_2A Receptor Ligands. ChemMedChem. 6(12). 2302–2311. 22 indexed citations

13.

Jacobson, Kenneth A., et al.. (2011). Allosteric Modulation of Purine and Pyrimidine Receptors. Advances in pharmacology. 61. 187–220. 27 indexed citations

14.

Fredholm, Bertil B., Adriaan P. IJzerman, Kenneth A. Jacobson, Joel Linden, & Christa E. Müller. (2011). International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update. Pharmacological Reviews. 63(1). 1–34. 1079 indexed citations breakdown →

15.

Jaakola, Veli‐Pekka, Mark T. Griffith, Michael A. Hanson, et al.. (2008). The 2.6 Angstrom Crystal Structure of a Human A _2A Adenosine Receptor Bound to an Antagonist. Science. 322(5905). 1211–1217. 1475 indexed citations breakdown →

16.

Schaick, E.A. van, et al.. (1998). Selectivity of action of 8‐alkylamino analogues of N⁶‐cyclopentyladenosine in vivo: haemodynamic versus anti‐lipolytic responses in rats. British Journal of Pharmacology. 124(3). 607–618. 35 indexed citations

17.

Beukers, Margot W., et al.. (1994). Nucleoside transport inhibition and platelet aggregation in human blood: R75231 and its enantiomers, draflazine and R88016. European Journal of Pharmacology Molecular Pharmacology. 266(1). 57–62. 16 indexed citations

18.

IJzerman, Adriaan P., et al.. (1991). Radioligand Binding Studies on the Nucleoside Transport Protein. Advances in experimental medicine and biology. 309A. 411–414.

19.

IJzerman, Adriaan P., et al.. (1990). The relationship between ionization and affinity of nucleoside transport inhibitors. Naunyn-Schmiedeberg s Archives of Pharmacology. 342(3). 336–41. 7 indexed citations

20.

IJzerman, Adriaan P.. (1988). Limiting Solubilities and lonization Constants of Sparingly Soluble Compounds: Determination from Aqueous Potentiometric Titration Data Only. Pharmaceutical Research. 5(12). 772–775. 6 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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