Igor B. Roninson

26.2k citations

158 papers · 18.1k indexed · 9 hit papers · h-index 67

Impact in

Oncology top 0.05%
- Drug Transport and Resistance Mechanisms
- Cancer-related Molecular Pathways
Molecular Biology top 0.2%
- Cancer therapeutics and mechanisms
- RNA Interference and Gene Delivery
- DNA Repair Mechanisms

Papers in

Oncology 98
- Drug Transport and Resistance Mechanisms 48
- Cancer-related Molecular Pathways 39
Molecular Biology 107
- Cancer therapeutics and mechanisms 24
- DNA and Nucleic Acid Chemistry 17
- DNA Repair Mechanisms 16
- RNA Interference and Gene Delivery 12

Co-authors: Eugenia V. Broude Michael M. Gottesman Janice E. Chin Ira Pastan Preet M. Chaudhary Bey-Dih Chang Kazumitsu Ueda Douglas P. Clark
Journals: Proceedings of the National Academy of Sciences (21 papers)Cancer Research (14 papers)Molecular and Cellular Biology (8 papers)Journal of Biological Chemistry (7 papers)Cell Cycle (7 papers)
Partner nations: United States Japan Russia

In The Last Decade

Igor B. Roninson

154 papers receiving 17.6k citations

Hit Papers

9 papers align trajectories log scale

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein 2019 · 372 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2019 Science
2003 PubMed
2001 Drug Resistance Updates
2001 Genes & Development
1991 Cell
1990 Proceedings of the National Academy of Sciences
1986 Cell
1986 Science
1986 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by Igor B. Roninson

Since Specialization

Citations

This map shows the geographic impact of Igor B. Roninson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Igor B. Roninson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Igor B. Roninson more than expected).

Fields of papers citing papers by Igor B. Roninson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Igor B. Roninson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Igor B. Roninson. The network helps show where Igor B. Roninson may publish in the future.

Co-authors

The 25 scholars most cited alongside Igor B. Roninson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Igor B. Roninson Line = papers co-authored together Igor B. Roninson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structural insight into substrate and inhibitor discrimination by human P-glycoprotein Science ·Amer Alam, Julia Kowal, Eugenia V. Broude, Igor B. Roninson, Kaspar P. Locher Hit paper breakdown →	2019	372
2	CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases Cancer Research ·Jiaxin Liang, Mengqian Chen, Daniel Hughes, Alexander A. Chumanevich, Serena Altilia, Vimala Kaza, Chang‐Uk Lim, Hippokratis Kiaris, Karthikeyan Mythreye, Maria Marjorette O. Peña, Eugenia V. Broude, Igor B. Roninson	2018	68
3	A subunit of coatomer protein complex offers a novel tumor-specific target through a surprising mechanism Autophagy ·Michael Shtutman, Igor B. Roninson	2011	11
4	Molecular remodeling of potassium channels in fibroblasts from centenarians: A marker of longevity? Mechanisms of Ageing and Development ·Isabella Zironi, Paolo Gaibani, Daniel Remondini, Stefano Salvioli, Serena Altilia, Michela Pierini, Giorgio Aicardi, E. Verondini, Luciano Milanesi, Ferdinando Bersani, Silvia Gravina, Igor B. Roninson, Claudio Franceschi, Gastone Castellani	2010	6
5	Abstract #5552: BSI-201 enhances the activity of multiple classes of cytotoxic agents and irradiation in triple negative breast cancer Cancer Research ·Valeria Ossovskaya, Lingyun Li, Eugenia V. Broude, Chang‐Uk Lim, Igor B. Roninson, C. R. Bradley, Barry M. Sherman	2009	13
6	Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro British Journal of Cancer ·Maria Prencipe, Patricia Fitzpatrick, Scott D. Gorman, CLOVIS HENRIQUE M FONSECA, Alicia M de Vries, Fiona Furlong, Armijos Alvarado, Darran P. O’Connor, Igor B. Roninson, Joe M. O’Sullivan, Amanda McCann	2009	46
7	Repression of the SUMO‐specific protease Senp1 induces p53‐dependent premature senescence in normal human fibroblasts Aging Cell ·Kristin Yates, Gregory A. Korbel, Michael Shtutman, Igor B. Roninson, Daniel DiMaio	2008	58
8	p21Waf1/Cip1/Sdi1 mediates retinoblastoma protein degradation Oncogene ·Eugenia V. Broude, Mari E. Swift, Claire Vivo, C. Detlefs, Brian M. Davis, Swathi Kalurupalle, Mikhail V. Blagosklonny, Igor B. Roninson	2007	67
9	Cell Adhesion Molecule L1 Disrupts E-Cadherin-Containing Adherens Junctions and Increases Scattering and Motility of MCF7 Breast Carcinoma Cells Cancer Research ·Michael Shtutman, Elina Levina, Patrice Ohouo, Mirza S. Baig, Igor B. Roninson	2006	112
10	Proteomic analysis of factors released from p21‐overexpressing tumour cells PROTEOMICS ·Yu Xuya, Darran P. O’Connor, L.A. Uvidia-Armijo, Frank Ring, Nathan Harris, Kenneth A. Dawson, Michael J. Dünn, Stephen R. Pennington, Igor B. Roninson, William M. Gallagher	2006	11
11	Identification of potential anticancer drug targets through the selection of growth-inhibitory genetic suppressor elements Cancer Cell ·Thomas Primiano, Mirza S. Baig, 殷嘉徽, Bey-Dih Chang, M Pucci, A T De Souza, F. Paratore, Tatyana A. Holzmayer, Igor B. Roninson	2003	5
12	Induction of senescence‐associated growth inhibitors in the tumor‐suppressive function of retinoids Journal of Cellular Biochemistry ·Igor B. Roninson, Milos Dokmanovic	2002	34
13	Activation of the LRP (lung resistance-related protein) gene by short-term exposure of human leukemia cells to phorbol ester and cytarabine. PubMed ·Pavel G. Komarov, Аlexander А. Shtil, Oksana Holian, Sam Lindsley, Lela Buckingham, Eugene Mechetner, Igor B. Roninson, John S. Coon	1998	20
14	Applications of green fluorescent protein as a marker of retroviral vectors Somatic Cell and Molecular Genetics ·Eugene Kandel, Bey-Dih Chang, Brigitte Schott, Аlexander А. Shtil, Andrei V. Gudkov, Igor B. Roninson	1997	30
15	Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis Cancer Letters ·Rong Yu, Аlexander А. Shtil, Tse‐Hua Tan, Igor B. Roninson, Ah‐Ng Tony Kong	1996	93
16	Variable effects of sodium butyrate on the expression and function of the MDR 1 (P‐glycoprotein) gene in colon carcinoma cell lines International Journal of Cancer ·Thomas O. Frommel, John S. Coon, T Tsuruo, Igor B. Roninson	1993	31
17	Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P‐glycoprotein International Journal of Cancer ·Alfred H. Schinkel, Piet Borst, Жданова Галина Олеговна, Els Wagenaar, Martijn E.T. Dollé, R.J. Arceci, Frank Baas, Takashi Tsuruo, Eugene Mechetner, Igor B. Roninson	1993	66
18	Clinical Correlates of MDR1 (P-glycoprotein) Gene Expression in Ovarian and Small-Cell Lung Carcinomas JNCI Journal of the National Cancer Institute ·Tatyana A. Holzmayer, Susan G. Hilsenbeck, Daniel D. Von Hoff, Igor B. Roninson	1992	151
19	The role of the MDR1 (p-glycoprotein) gene in multidrug resistance in vitro and in vivo Biochemical Pharmacology ·Igor B. Roninson	1992	162
20	mRNA phenotyping by enzymatic amplification of randomly primed cDNA Nucleic Acids Research ·Kevin E. Noonan, Igor B. Roninson	1988	129

About Igor B. Roninson

Igor B. Roninson is a scholar working on Oncology, Molecular Biology, Infectious Diseases, Biotechnology and Cancer Research, having authored 158 papers that have together received 18.1k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (48 papers), Cancer-related Molecular Pathways (39 papers), Cancer therapeutics and mechanisms (24 papers), DNA and Nucleic Acid Chemistry (17 papers), DNA Repair Mechanisms (16 papers), HIV/AIDS drug development and treatment (14 papers), Advanced Breast Cancer Therapies (13 papers) and RNA Interference and Gene Delivery (12 papers). The work is most often cited by research in Oncology (10.6k citations), Molecular Biology (11.1k citations), Aging (178 citations), Cancer Research (1.4k citations) and Pediatrics, Perinatology and Child Health (1.8k citations). Igor B. Roninson has collaborated with scholars based in United States, Japan and Russia. Frequent co-authors include Eugenia V. Broude, Michael M. Gottesman, Janice E. Chin, Ira Pastan, Preet M. Chaudhary, Bey-Dih Chang, Kazumitsu Ueda, Douglas P. Clark, Kevin E. Noonan and Eugene Mechetner. Their work appears in journals such as Proceedings of the National Academy of Sciences, Cancer Research, Molecular and Cellular Biology, Journal of Biological Chemistry and Cell Cycle.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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