Hwei‐Ru Tsou

2.2k citations

24 papers · 1.9k indexed · 1 hit paper · h-index 17

Oncology top 5%
Organic Chemistry top 2%
Molecular Biology top 10%
Pulmonary and Respiratory Medicine top 5%
Radiology, Nuclear Medicine and Imaging top 5%

Co-authors: Ramaswamy Nilakantan Allan Wissner Ru Shen Marvin F. Reich Bernard D. Johnson M. Brawner Floyd Sridhar K. Rabindran Carolyn Discafani
Topics: HER2/EGFR in Cancer Research (7 papers)Quinazolinone synthesis and applications (6 papers)Chemical Synthesis and Analysis (3 papers)
Cited by: Oncology Organic Chemistry Genetics
Journals: Cancer Research Journal of Medicinal Chemistry The Journal of Organic Chemistry
Partner nations: United States Canada Germany

In The Last Decade

Hwei‐Ru Tsou

24 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Antitumor Activity of HKI-272, an Orally Active, Irreversible Inhibitor of the HER-2 Tyrosine Kinase

2004 503 citations Sridhar K. Rabindran, Carolyn Discafani et al. profile →

Peers

Countries citing papers authored by Hwei‐Ru Tsou

Since Specialization

Citations

This map shows the geographic impact of Hwei‐Ru Tsou's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hwei‐Ru Tsou with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hwei‐Ru Tsou more than expected).

Fields of papers citing papers by Hwei‐Ru Tsou

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hwei‐Ru Tsou. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hwei‐Ru Tsou. The network helps show where Hwei‐Ru Tsou may publish in the future.

Co-authorship network of co-authors of Hwei‐Ru Tsou

This figure shows the co-authorship network connecting the top 25 collaborators of Hwei‐Ru Tsou. A scholar is included among the top collaborators of Hwei‐Ru Tsou based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hwei‐Ru Tsou. Hwei‐Ru Tsou is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	4-Substituted-7-azaindoles bearing a ureidobenzofuranone moiety as potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR) 2010 ·Bioorganic & Medicinal Chemistry Letters ·Hwei‐Ru Tsou,(unknown),Gary H. Birnberg,Nan Zhang,Natasja Brooijmans,Lourdes Toral‐Barza,Irwin Hollander,Semiramis Ayral‐Kaloustian,Ker Yu	19
2	Discovery and optimization of 2-(4-substituted-pyrrolo[2,3-b]pyridin-3-yl)methylene-4-hydroxybenzofuran-3(2H)-ones as potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR) 2010 ·Bioorganic & Medicinal Chemistry Letters ·Hwei‐Ru Tsou,(unknown),Gary H. Birnberg,G Grosu,Matthew G. Bursavich,Joel Bard,Natasja Brooijmans,Lourdes Toral‐Barza,Irwin Hollander,Tarek S. Mansour,Semiramis Ayral‐Kaloustian,Ker Yu	34
3	Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment 2008 ·Bioorganic & Medicinal Chemistry Letters ·Scott C. Mayer,(unknown),Frank Boschelli,Li Di,Mark R. Johnson,Cynthia Hess Kenny,Girija Krishnamurthy,Kristina M. K. Kutterer,F. Moy,Susan Petusky,Malini Ravi,Diane Tkach,Hwei‐Ru Tsou,Weixin Xu	60
4	Palladium-catalyzed arylation of N,N-dialkylhydrazines and the subsequent conversion to anilines 2007 ·Tetrahedron Letters ·Xiaoxiang Liu,(unknown),Hwei‐Ru Tsou	14
5	Optimization of 6,7-Disubstituted-4-(arylamino)quinoline-3-carbonitriles as Orally Active, Irreversible Inhibitors of Human Epidermal Growth Factor Receptor-2 Kinase Activity 2005 ·Journal of Medicinal Chemistry ·Hwei‐Ru Tsou,(unknown),William Hallett,Marvin F. Reich,M. Brawner Floyd,Bernard D. Johnson,Ronald S. Michalak,Ramaswamy Nilakantan,Carolyn Discafani,Jonathan Golas,Sridhar K. Rabindran,Ru Shen,Xiaoqing Shi,Yu‐Fen Wang,Janis Upeslacis,Allan Wissner	246
6	Pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides as novel anti-proliferative agents: parallel synthesis for lead optimization of amide region 2005 ·Bioorganic & Medicinal Chemistry Letters ·Ariamala Gopalsamy,Hui Yang,John W. Ellingboe,Hwei‐Ru Tsou,Nan Zhang,(unknown),Dennis Powell,Miriam Miranda,John P. McGinnis,Sridhar K. Rabindran	56
7	Syntheses and EGFR and HER‐2 Kinase Inhibitory Activities of 4‐Anilinoquinoline‐3‐carbonitriles: Analogues of Three Important 4‐Anilinoquinazolines Currently Undergoing Clinical Evaluation as Therapeutic Antitumor Agents. 2003 ·ChemInform ·Allan Wissner,M. Brawner Floyd,Sridhar K. Rabindran,Ramaswamy Nilakantan,Lee M. Greenberger,Ru Shen,Yufen Wang,Hwei‐Ru Tsou	1
8	Synthesis and Structure−Activity Relationships of 6,7-Disubstituted 4-Anilinoquinoline-3-carbonitriles. The Design of an Orally Active, Irreversible Inhibitor of the Tyrosine Kinase Activity of the Epidermal Growth Factor Receptor (EGFR) and the Human Epidermal Growth Factor Receptor-2 (HER-2) 2002 ·Journal of Medicinal Chemistry ·Allan Wissner,(unknown),Marvin F. Reich,M. Brawner Floyd,Bernard D. Johnson,Nellie Mamuya,Edward Rosfjord,Carolyn Discafani,Rachel E. Davis,Xiaoqing Shi,Sridhar K. Rabindran,(unknown),Fei Ye,William Hallett,Ramaswamy Nilakantan,Ru Shen,Yu‐Fen Wang,Lee M. Greenberger,Hwei‐Ru Tsou	212
9	Syntheses and EGFR and HER-2 kinase inhibitory activities of 4-anilinoquinoline-3-carbonitriles: analogues of three important 4-anilinoquinazolines currently undergoing clinical evaluation as therapeutic antitumor agents 2002 ·Bioorganic & Medicinal Chemistry Letters ·Allan Wissner,M. Brawner Floyd,Sridhar K. Rabindran,Ramaswamy Nilakantan,Lee M. Greenberger,Ru Shen,Yufen Wang,Hwei‐Ru Tsou	54
10	ChemInform Abstract: 6‐Substituted‐4‐(3‐bromophenylamino)quinazolines as Putative Irreversible Inhibitors of the Epidermal Growth Factor Receptor (EGFR) and Human Epidermal Growth Factor Receptor (HER‐2) Tyrosine Kinases with Enhanced Antitumor Activity. 2001 ·ChemInform ·Hwei‐Ru Tsou,(unknown)	1
11	6-Substituted-4-(3-bromophenylamino)quinazolines as Putative Irreversible Inhibitors of the Epidermal Growth Factor Receptor (EGFR) and Human Epidermal Growth Factor Receptor (HER-2) Tyrosine Kinases with Enhanced Antitumor Activity 2001 ·Journal of Medicinal Chemistry ·Hwei‐Ru Tsou,Nellie Mamuya,Bernard D. Johnson,Marvin F. Reich,(unknown),Fei Ye,Ramaswamy Nilakantan,Ru Shen,Carolyn Discafani,(unknown),Rachel E. Davis,Frank E. Koehn,Lee M. Greenberger,Yufen Wang,Allan Wissner	227
12	4-Anilino-6,7-dialkoxyquinoline-3-carbonitrile Inhibitors of Epidermal Growth Factor Receptor Kinase and Their Bioisosteric Relationship to the 4-Anilino-6,7-dialkoxyquinazoline Inhibitors 2000 ·Journal of Medicinal Chemistry ·Allan Wissner,Dan M. Berger,Diane H. Boschelli,M. Brawner Floyd,Lee M. Greenberger,(unknown),Bernard D. Johnson,Nellie Mamuya,Ramaswamy Nilakantan,Marvin F. Reich,Ru Shen,Hwei‐Ru Tsou,Erik Upeslacis,(unknown),Biqi Wu,Fei Ye,Nan Zhang	183
13	SRF Binding to SRE in the Rat Heart: Influence of Age 1998 ·The Journals of Gerontology Series A ·Xiangyi Lu,Gohar Azhar,Lei Liu,Hwei‐Ru Tsou,Jeanne Y. Wei	18
14	Determination of the loading values for high levels of drugs and sugars conjugated to proteins by matrix-assisted ultraviolet laser desorption/ionization mass spectrometry 1993 ·Journal of Mass Spectrometry ·Marshall M. Siegel,Hwei‐Ru Tsou,Baiwei Lin,Irwin Hollander,Allan Wissner,Michael Karas,Arnd Ingendoh,Franz Hillenkamp	8
15	Biosynthetic origin of the carbon skeleton and oxygen atoms of the LL-F28249.ALPHA., apoent antiparasitic macrolide. 1989 ·The Journal of Antibiotics ·Hwei‐Ru Tsou,Zafar Ahmed,(unknown),Milon W. Bullock,(unknown),Joseph J. Goodman,Donald B. Borders	21
16	Biosynthesis of the antibiotic maduramicin. Origin of the carbon and oxygen atoms as well as the 13C NMR assignments. 1984 ·The Journal of Antibiotics ·Hwei‐Ru Tsou,Srinivasan Thirumalai Rajan,(unknown),Patrick C. Mowery,Milon W. Bullock,Donald B. Borders,John C. James,John H. Martin,G. O. MORTON	19
17	Natural abundance two-dimensional double-quantum 13C nmr spectroscopy of maduramicin, a polyether ionophore antibiotic and coccidiostat. 1984 ·The Journal of Antibiotics ·Srinivasan Thirumalai Rajan,Hwei‐Ru Tsou,Patrick C. Mowery,Milon W. Bullock,Gerald W. Stockton	12
18	Studies on the role of protein synthesis and of sodium on the regulation of ornithine decarboxylase activity 1982 ·Biochimica et Biophysica Acta (BBA) - General Subjects ·Dace Viceps‐Madore,Kuang Yu Chen,Hwei‐Ru Tsou,E.S. Canellakis	32
19	A novel synthesis of α‐N‐methyl‐¹⁴C‐DL‐asparagine by generation of methylamine‐¹⁴C insitu 1981 ·Journal of Labelled Compounds and Radiopharmaceuticals ·Hwei‐Ru Tsou	1
20	Procedure for diethoxymethylation of ketones 1981 ·The Journal of Organic Chemistry ·William L. Mock,Hwei‐Ru Tsou	20

About Hwei‐Ru Tsou

Hwei‐Ru Tsou is a scholar working on Organic Chemistry, Oncology and Physiology, having authored 24 papers that have together received 1.9k indexed citations. Recurring topics across this work include HER2/EGFR in Cancer Research (7 papers), Quinazolinone synthesis and applications (6 papers) and Chemical Synthesis and Analysis (3 papers). The work is most often cited by research in Oncology (882 citations), Organic Chemistry (823 citations) and Genetics (153 citations). Hwei‐Ru Tsou has collaborated with scholars based in United States, Canada and Germany. Frequent co-authors include Ramaswamy Nilakantan, Allan Wissner, Ru Shen, Marvin F. Reich, Bernard D. Johnson, M. Brawner Floyd, Sridhar K. Rabindran, Carolyn Discafani, Yu‐Fen Wang and William Hallett. Their work appears in journals such as Cancer Research, Journal of Medicinal Chemistry and The Journal of Organic Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact