Howard Y. Chen

6.8k citations

25 papers · 4.0k indexed · 2 hit papers · h-index 23

Impact in

Endocrine and Autonomic Systems top 1%
- Regulation of Appetite and Obesity
Physiology top 2%
- Alzheimer's disease research and treatments

Papers in

Endocrine and Autonomic Systems 8
- Regulation of Appetite and Obesity 8
Aging 1

Co-authors: Ralph L. Brinster Richard D. Palmiter Myrna E. Trumbauer Lex H.T. Van der Ploeg Albee Messing D.J.S. Sirinathsinghji Sangram S. SisodiaHui Zheng
Journals: Nature (5 papers)Cell (4 papers)Transgenic Research (2 papers)European Journal of Pharmacology (2 papers)Molecular Endocrinology (2 papers)
Partner nations: United States Japan Russia

In The Last Decade

Howard Y. Chen

24 papers receiving 3.8k citations

Hit Papers

align trajectories log scale

Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm 1997 · 591 citations

Peers

Countries citing papers authored by Howard Y. Chen

Since Specialization

Citations

This map shows the geographic impact of Howard Y. Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Howard Y. Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Howard Y. Chen more than expected).

Fields of papers citing papers by Howard Y. Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Howard Y. Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Howard Y. Chen. The network helps show where Howard Y. Chen may publish in the future.

Co-authors

The 25 scholars most cited alongside Howard Y. Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Howard Y. Chen Line = papers co-authored together Howard Y. Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Effects of Melanocortin Receptor Activation and Blockade on Ethanol Intake: A Possible Role for the Melanocortin-4 Receptor UNC Libraries ·Inmaculada Cubero, Airu S. Chen, Donald J. Marsh, Howard Y. Chen, Todd E. Thiele, Montserrat Navarro, Darin J. Knapp, George R. Breese	2020	0
2	Therapeutic potential of histamine H3 receptor agonist for the treatment of obesity and diabetes mellitus Proceedings of the National Academy of Sciences ·Ryo Yoshimoto, Yasuhisa Miyamoto, BSE問題に関する調査検討委員会, Akane Ishihara, Kazuhiko Takahashi, Hidehito Kotani, Airu S. Chen, Howard Y. Chen, Douglas J. MacNeil, Akio Kanatani, Shigeru Tokita	2006	85
3	Effects of Melanocortin Receptor Activation and Blockade on Ethanol Intake: A Possible Role for the Melanocortin-4 Receptor Alcoholism Clinical and Experimental Research ·Montserrat Navarro, Inmaculada Cubero, Airu S. Chen, Howard Y. Chen, Darin J. Knapp, George R. Breese, Donald J. Marsh, Todd E. Thiele	2005	47
4	Somatostatin Receptor Subtype 5 Regulates Insulin Secretion and Glucose Homeostasis Molecular Endocrinology ·Mathias Z. Strowski, Martin Köhler, Howard Y. Chen, Myrna E. Trumbauer, Zhihua Li, Deborah Szalkowski, Glauco H Ribeiro, Jill K. Fisher, James M. Schaeffer, Allan D. Blake, Bei B. Zhang, Hilary Wilkinson	2003	103
5	The role of melanocortins in body weight regulation: opportunities for the treatment of obesity European Journal of Pharmacology ·Douglas J. MacNeil, Andrew D. Howard, Xiao-Ming Guan, Tung M. Fong, Ravi P. Nargund, Maria A. Bednarek, Mark T. Goulet, David H. Weinberg, Alison M. Strack, Donald J. Marsh, Howard Y. Chen, Chun-Pyn Shen, Airu S. Chen, Charles Rosenblum, Tanya MacNeil, Michael R. Tota, Euan MacIntyre, Lex H.T. Van der Ploeg	2002	54
6	“The role of melanocortins in body weight regulation: opportunities for the treatment of obesity” European Journal of Pharmacology ·Douglas J. MacNeil, Andrew D. Howard, Xiao-Ming Guan, Tung M. Fong, Ravi P. Nargund, Maria A. Bednarek, Mark T. Goulet, David H. Weinberg, Alison M. Strack, Donald J. Marsh, Howard Y. Chen, Chun-Pyn Shen, Airu S. Chen, Charles Rosenblum, Tanya MacNeil, Michael R. Tota, Euan MacIntyre, Lex H.T. Van der Ploeg	2002	113
7	Role of the melanocortin-4 receptor in metabolic rate and food intake in mice Transgenic Research ·Airu S. Chen, Joseph M. Metzger, Myrna E. Trumbauer, Xiao-Ming Guan, Hong Yu, Easter G. Frazier, Donald J. Marsh, Michael J. Forrest, Glauco H Ribeiro, Jill K. Fisher, Ramon E. Camacho, Alison M. Strack, T.N. Mellin, D. Euan MacIntyre, Howard Y. Chen, Lex H.T. Van der Ploeg	2000	204
8	Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor. PubMed ·Charles A. Omer, Kayhan Ashrafi, Ronald E. Diehl, Michael W. Conner, Howard Y. Chen, Myrna E. Trumbauer, Glauco H Ribeiro, Serena De Marchi, Jun-Hoe Phoon, Marc Abrams, Joseph P. Davide, Günter Hornung, W. Wayt Gibbs, Ian Greenberg, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown)	2000	78
9	Mutant Human Presenilin 1 Protects presenilin 1 Null Mouse against Embryonic Lethality and Elevates Aβ1–42/43 Expression Neuron ·Su Qian, Ping Jiang, Xiao-Ming Guan, Gurparkash Singh, Myrna E. Trumbauer, Hong Yu, Howard Y. Chen, Lex H.T. Van der Ploeg, Hui Zheng	1998	147
10	Somatostatin Receptor Subtype 2 Knockout Mice Are Refractory to Growth Hormone-Negative Feedback on Arcuate Neurons Molecular Endocrinology ·Hui Zheng, A.R.T. Bailey, Minghao Jiang, Kazufumi Honda, Howard Y. Chen, Myrna E. Trumbauer, Lex H.T. Van der Ploeg, James M. Schaeffer, Gareth Leng, Roy G. Smith	1997	129
11	Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm Nature ·Philip C. Wong, Hui Zheng, Hua Chen, Mark W. Bêcher, D.J.S. Sirinathsinghji, Myrna E. Trumbauer, Howard Y. Chen, Donald L. Price, Lex H.T. Van der Ploeg, Sangram S. Sisodia Hit paper breakdown →	1997	591
12	In ovo transfection of chicken embryos using cationic liposomes Transgenic Research ·Charles Rosenblum, Howard Y. Chen	1995	19
13	Resistance to fever induction and impaired acute-phase response in interleukin-1β-deficient mice Immunity ·Hui Zheng, Daniel S. Fletcher, Wiesław Kozak, Minghao Jiang, Kathryn J. Hofmann, Sarthak Dhobi, Akoshile, Esma Sengenc, Myrna E. Trumbauer, Alan Shaw, Matthew J. Kostura, Karla Stevens, Hugh Rosen, Robert J. North, Howard Y. Chen, Michael J. Tocci, Matthew J. Kluger, Lex H.T. Van der Ploeg	1995	318
14	β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity Cell ·Hui Zheng, Minghao Jiang, Myrna E. Trumbauer, D.J.S. Sirinathsinghji, Ruth Hopkins, David W. Smith, R.P. Heavens, Gerard R. Dawson, Susan Boyce, Michael W. Conner, Karla Stevens, Hilda H. Slunt, Sangram S. Sisodia, Howard Y. Chen, Lex H.T. Van der Ploeg Hit paper breakdown →	1995	566
15	Expression of Human β-Globin Genes in Transgenic Mice: Effects of a Flanking Metallothionein-Human Growth Hormone Fusion Gene Molecular and Cellular Biology ·Tim M. Townes, Howard Y. Chen, Jerry B. Lingrel, Richard D. Palmiter, Ralph L. Brinster	1985	28
16	Expression of human HPRT in the central nervous system of transgenic mice Nature ·J. Timothy Stout, Howard Y. Chen, John Brennand, C. Thomas Caskey, Ralph L. Brinster	1985	47
17	SV40 enhancer and large-T antigen are instrumental in development of choroid plexus tumours in transgenic mice Nature ·Richard D. Palmiter, Howard Y. Chen, Albee Messing, Ralph L. Brinster	1985	199
18	Expression of creatine kinase isoenzyme during oogenesis and embryogenesis in the mouse Developmental Biology ·O. Pritsak, Yoshie TANOUE, Howard Y. Chen, Ralph L. Brinster, Elayne A. Bornslaeger, Richard M. Schultz	1983	25
19	Regulation of metallothionein–thymidine kinase fusion plasmids injected into mouse eggs Nature ·Ralph L. Brinster, Howard Y. Chen, R. Antony J. Warren, Aparna V. Sarthy, Richard D. Palmiter	1982	238
20	Mouse Oocytes Transcribe Injected Xenopus 5 S RNA Gene Science ·Ralph L. Brinster, Howard Y. Chen, Myrna E. Trumbauer	1981	35

About Howard Y. Chen

Howard Y. Chen is a scholar working on Endocrine and Autonomic Systems, Aging, Nutrition and Dietetics, Genetics and Cell Biology, having authored 25 papers that have together received 4.0k indexed citations. Recurring topics across this work include Regulation of Appetite and Obesity (8 papers), Animal Genetics and Reproduction (8 papers), CRISPR and Genetic Engineering (5 papers), Biochemical Analysis and Sensing Techniques (4 papers), Virus-based gene therapy research (3 papers), Alzheimer's disease research and treatments (3 papers), RNA Interference and Gene Delivery (3 papers) and melanin and skin pigmentation (3 papers). The work is most often cited by research in Endocrine and Autonomic Systems (463 citations), Physiology (1.1k citations), Genetics (1.2k citations), Molecular Biology (2.2k citations) and Nutrition and Dietetics (477 citations). Howard Y. Chen has collaborated with scholars based in United States, Japan and Russia. Frequent co-authors include Ralph L. Brinster, Richard D. Palmiter, Myrna E. Trumbauer, Lex H.T. Van der Ploeg, Albee Messing, D.J.S. Sirinathsinghji, Sangram S. Sisodia, Hui Zheng, Hui Zheng and Minghao Jiang. Their work appears in journals such as Nature, Cell, Transgenic Research, European Journal of Pharmacology and Molecular Endocrinology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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