Hidehito Kotani

4.7k total citations · 2 hit papers
42 papers, 3.4k citations indexed

About

Hidehito Kotani is a scholar working on Molecular Biology, Oncology and Immunology. According to data from OpenAlex, Hidehito Kotani has authored 42 papers receiving a total of 3.4k indexed citations (citations by other indexed papers that have themselves been cited), including 34 papers in Molecular Biology, 12 papers in Oncology and 7 papers in Immunology. Recurrent topics in Hidehito Kotani's work include Cancer-related Molecular Pathways (9 papers), Mast cells and histamine (7 papers) and Circadian rhythm and melatonin (5 papers). Hidehito Kotani is often cited by papers focused on Cancer-related Molecular Pathways (9 papers), Mast cells and histamine (7 papers) and Circadian rhythm and melatonin (5 papers). Hidehito Kotani collaborates with scholars based in Japan, United States and China. Hidehito Kotani's co-authors include Shinji Mizuarai, Kazuhiko Takahashi, Naohiko Aozasa, Hiraku Itadani, Yoko Nakatsuru, Hiroshi Hirai, Yoko Ueno, Harold Hatch, Shunsuke Taguchi and Bo‐Sheng Pan and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Hidehito Kotani

42 papers receiving 3.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

2010 760 citations Hiroshi Hirai, Hiroshi Sootome et al. Molecular Cancer Therapeutics profile →
Role of the Toll-like Receptor 4/NF-κB Pathway in Saturated Fatty Acid–Induced Inflammatory Changes in the Interaction Between Adipocytes and Macrophages

2006 641 citations Shinji Mizuarai, Hidehito Kotani et al. profile →

Peers

Countries citing papers authored by Hidehito Kotani

Since Specialization

Citations

This map shows the geographic impact of Hidehito Kotani's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hidehito Kotani with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hidehito Kotani more than expected).

Fields of papers citing papers by Hidehito Kotani

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hidehito Kotani. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hidehito Kotani. The network helps show where Hidehito Kotani may publish in the future.

Co-authorship network of co-authors of Hidehito Kotani

This figure shows the co-authorship network connecting the top 25 collaborators of Hidehito Kotani. A scholar is included among the top collaborators of Hidehito Kotani based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hidehito Kotani. Hidehito Kotani is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Expression ratio of CCND1 to CDKN2A mRNA predicts RB1 status of cultured cancer cell lines and clinical tumor samples 2011 ·Molecular Cancer ·Shinji Mizuarai, Takumitsu Machida, Tsutomu Kobayashi, (unknown), Hiraku Itadani, Hidehito Kotani	19
2	MK-5108, a Highly Selective Aurora-A Kinase Inhibitor, Shows Antitumor Activity Alone and in Combination with Docetaxel 2010 ·Molecular Cancer Therapeutics ·Toshiyasu Shimomura, (unknown), Yoko Nakatsuru, Takashi Mita, K. Ichikawa, Tsutomu Kodera, Takumi Sakai, Tadahiro Nambu, Mayu Miyamoto, Ikuko Takahashi, Satomi Miki, Nobuhiko Kawanishi, Mitsuru Ohkubo, Hidehito Kotani, Yoshikazu Iwasawa	100
3	MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo breakdown → 2010 ·Molecular Cancer Therapeutics ·Hiroshi Hirai, Hiroshi Sootome, Yoko Nakatsuru, Katsuyoshi Miyama, Shunsuke Taguchi, (unknown), Yoko Ueno, Harold Hatch, Pradip K. Majumder, Bo‐Sheng Pan, Hidehito Kotani	760
4	Synthetic lethal interactions for the development of cancer therapeutics: biological and methodological advancements 2010 ·Human Genetics ·Shinji Mizuarai, Hidehito Kotani	15
5	Biological characterization of 2-aminothiazole-derived Cdk4/6 selective inhibitor in vitro and in vivo 2010 ·Cell Cycle ·Hiroshi Hirai, Toshiyasu Shimomura, Makiko Kobayashi, (unknown), Eri Taniguchi, Kazuhiro Fukasawa, Takumitsu Machida, (unknown), Tsuyoshi Arai, K. Ichikawa, (unknown), Kyosuke Haze, Tsutomu Kodera, Nobuhiko Kawanishi, (unknown), Yoko Nakatsuru, Hidehito Kotani, Yoshikazu Iwasawa	12
6	Structures of the PKC-ι kinase domain in its ATP-bound and apo forms reveal defined structures of residues 533–551 in the C-terminal tail and their roles in ATP binding 2010 ·Acta Crystallographica Section D Biological Crystallography ·(unknown), Kenji Kamata, Kazuhiro Fukasawa, Hirokazu Ohsawa, (unknown), Takashi Yoshizumi, Ikuko Takahashi, Hidehito Kotani, Yoshikazu Iwasawa	32
7	Expression levels of p18INK4C modify the cellular efficacy of cyclin-dependent kinase inhibitors via regulation of Mcl-1 expression in tumor cell lines 2009 ·Molecular Cancer Therapeutics ·(unknown), Hiraku Itadani, Toshiyasu Shimomura, Nobuhiko Kawanishi, Hiroshi Hirai, Hidehito Kotani	12
8	Induction of Prostaglandin E2 Pathway Promotes Gastric Hamartoma Development with Suppression of Bone Morphogenetic Protein Signaling 2009 ·Cancer Research ·Hiroko Oshima, Hiraku Itadani, Hidehito Kotani, Makoto M. Taketo, Masanobu Oshima	25
9	High-Throughput Assay for Long Chain Fatty Acyl-CoA Elongase Using Homogeneous Scintillation Proximity Format 2009 ·Assay and Drug Development Technologies ·(unknown), Yasuhisa Miyamoto, Hidefumi Kitazawa, Tsutomu Kobayashi, Hidehito Kotani, Shigeru Tokita	5
10	Expression levels of NF-Y target genes changed by CDKN1B correlate with clinical prognosis in multiple cancers 2009 ·Genomics ·Kazunori Yamanaka, Shinji Mizuarai, (unknown), Hiraku Itadani, Hiroshi Hirai, Hidehito Kotani	19
11	Imidazopyridine derivatives as potent and selective Polo-like kinase (PLK) inhibitors 2009 ·Bioorganic & Medicinal Chemistry Letters ·Yoshiyuki Satô, (unknown), T Sugimoto, (unknown), Kaori Kamijo, (unknown), Toshiaki Tsujino, Akiko Watanabe, Sachie Otsuki, Morihiro Mitsuya, Masato Iida, Kyosuke Haze, Takumitsu Machida, Yoko Nakatsuru, (unknown), Hidehito Kotani, Yoshikazu Iwasawa	46
12	Integrated Genomic and Pharmacological Approaches to Identify Synthetic Lethal Genes as Cancer Therapeutic Targets 2008 ·Current Molecular Medicine ·Shinji Mizuarai, Hiroki Irie, Dennis M. Schmatz, Hidehito Kotani	14
13	Can Systems Biology Understand Pathway Activation? Gene Expression Signatures as Surrogate Markers for Understanding the Complexity of Pathway Activation 2008 ·Current Genomics ·Hiraku Itadani, Shinji Mizuarai, Hidehito Kotani	28
14	Simultaneous fluorometric measurement of histamine and tele-methylhistamine levels in rodent brain by high-performance liquid chromatography 2004 ·Analytical Biochemistry ·Yasuhisa Miyamoto, Ryo Yoshimoto, Mariko Yumoto, Akane Ishihara, Kazuhiko Takahashi, Hidehito Kotani, Akio Kanatani, Shigeru Tokita	17
15	Adiposity Elevates Plasma MCP-1 Levels Leading to the Increased CD11b-positive Monocytes in Mice 2003 ·Journal of Biological Chemistry ·Kazuhiko Takahashi, Shinji Mizuarai, Hiromitsu Araki, Satoshi Mashiko, Akane Ishihara, Akio Kanatani, Hiraku Itadani, Hidehito Kotani	269
16	Vitamin D3 up-regulated protein-1 regulates collagen expression in mesangial cells 2003 ·Kidney International ·Tsutomu Kobayashi, Sayuri Uehara, Takanori Ikeda, Hiraku Itadani, Hidehito Kotani	63
17	Targeted disruption of H3 receptors results in changes in brain histamine tone leading to an obese phenotype 2002 ·Journal of Clinical Investigation ·Kazuhiko Takahashi, (unknown), (unknown), Hidehito Kotani	117
18	Increased resistance to collagen-induced arthritis in CD44-deficient DBA/1 mice 2001 ·Arthritis & Rheumatism ·Reinout Stoop, Hidehito Kotani, John D. McNeish, (unknown), Katalin Mikecz	44
19	A Role for RNA Synthesis in Homologous Pairing Events 1994 ·Molecular and Cellular Biology ·Hidehito Kotani, Eric B. Kmiec	10
20	DNA relaxation mediated by Ustilago maydis type I topoisomerase; modulation by chromatin associated proteins 1993 ·Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression ·Manimekalai M. Thiyagarajan, Hidehito Kotani, William K. Holloman, Eric B. Kmiec	7

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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