Hiroyuki Motoshima

11.9k citations

97 papers · 9.7k indexed · 1 hit paper · h-index 35

Cellular and Molecular Neuroscience top 0.5%
Molecular Biology top 0.5%
- Metabolism, Diabetes, and Cancer 20
- Protein Structure and Dynamics 12
- Peroxisome Proliferator-Activated Receptors 10
Endocrine and Autonomic Systems top 1%
Physiology top 1%
- Adipose Tissue and Metabolism 22
Physiology top 1%
- Adipose Tissue and Metabolism 22
Epidemiology
- Adipokines, Inflammation, and Metabolic Diseases 15
Materials Chemistry
- Enzyme Structure and Function 15
Surgery
- Pancreatic function and diabetes 15
Endocrinology, Diabetes and Metabolism
- Diabetes Treatment and Management 10

Co-authors: Barry J. Goldstein Takashi Kumasaka Ronald E. Stenkamp Krzysztof Palczewski Craig A. Behnke Tetsuya Hori David C. Teller Tetsuji Okada
Cited by: Cellular and Molecular Neuroscience Molecular Biology Endocrine and Autonomic Systems
Journals: Science (1 paper)Journal of Biological Chemistry (2 papers)PLoS ONE (2 papers)
Partner nations: Japan United States China

In The Last Decade

Hiroyuki Motoshima

94 papers receiving 9.4k citations

Hit Papers

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Peers

Countries citing papers authored by Hiroyuki Motoshima

Since Specialization

Citations

This map shows the geographic impact of Hiroyuki Motoshima's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hiroyuki Motoshima with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hiroyuki Motoshima more than expected).

Fields of papers citing papers by Hiroyuki Motoshima

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hiroyuki Motoshima. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hiroyuki Motoshima. The network helps show where Hiroyuki Motoshima may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Hiroyuki Motoshima, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hiroyuki Motoshima Line = papers co-authored together Hiroyuki Motoshima links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Hematopoietic dipeptidyl peptidase-4 deficiency promotes M2 macrophage polarization and attenuates atherosclerosis Biochemical and Biophysical Research Communications ·Yuqi Zhou,Takeshi Matsumura,Sho Saito,Yoshitaka Yagi,Tomoaki Yoshinaga,M. Takeshita,Kazuki Fukuda,Takafumi Senokuchi,Hiroyuki Motoshima,Tatsuya Kondo,Ryo Hatano,Kei Ohnuma,Chikao Morimoto,Eiichi Araki,Naoto Kubota	2025	0
2	Autoimmune Polyglandular Syndrome Type 3 Complicated with IgG4-related Disease Internal Medicine ·Yusuke Murata,M. Haneda,Nobukazu Miyakawa,Saiko Nishida,Nobuhiro Kajihara,Sarie Maeda,Kaoru Ono,Satoko Hanatani,Motoyuki Igata,Yuki Takaki,Hiroyuki Motoshima,Hideki Kishikawa,Eiichi Araki	2023	0
3	Hypoglycemia Induces Mitochondrial Reactive Oxygen Species Production Through Increased Fatty Acid Oxidation and Promotes Retinal Vascular Permeability in Diabetic Mice Antioxidants and Redox Signaling ·Ayaka Yoshinaga,Nobuhiro Kajihara,Daisuke Kukidome,Hiroyuki Motoshima,Takeshi Matsumura,Takeshi Nishikawa,Eiichi Araki	2020	20
4	Mineralocorticoid Receptor May Regulate Glucose Homeostasis through the Induction of Interleukin-6 and Glucagon-Like peptide-1 in Pancreatic Islets Journal of Clinical Medicine ·Rieko Goto,Tatsuya Kondo,Kaoru Ono,Sayaka Kitano,Nobukazu Miyakawa,Takuro Watanabe,Masaji Sakaguchi,Miki Sato,Motoyuki Igata,Junji Kawashima,Hiroyuki Motoshima,Takeshi Matsumura,Seiya Shimoda,Eiichi Araki	2019	4
5	Activation of heat shock response to treat obese subjects with type 2 diabetes: a prospective, frequency-escalating, randomized, open-label, triple-arm trial Scientific Reports ·Tatsuya Kondo,Rieko Goto,Kaoru Ono,Sayaka Kitano,Mary Ann Suico,Miki Sato,Motoyuki Igata,Junji Kawashima,Hiroyuki Motoshima,Takeshi Matsumura,Hirofumi Kai,Eiichi Araki	2016	10
6	Statins meditate anti-atherosclerotic action in smooth muscle cells by peroxisome proliferator-activated receptor-γ activation Biochemical and Biophysical Research Communications ·Kazuki Fukuda,Takeshi Matsumura,Takafumi Senokuchi,Norio Ishii,Hiroyuki Kinoshita,Sarie Yamada,Saiko Murakami,Saya Nakao,Hiroyuki Motoshima,Tatsuya Kondo,Daisuke Kukidome,Shuji Kawasaki,Teruo Kawada,Takeshi Nishikawa,Eiichi Araki	2014	22
7	Cloning, expression and purification of cold adapted acetate kinase from Shewanella species AS-11 AFRICAN JOURNAL OF BIOTECHNOLOGY ·Md. Abul Kashem Tang,Hiroyuki Motoshima,Keiichi Watanabe	2012	1
8	Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis Diabetes ·Tatsuya Kondo,Kazunari Sasaki,Rina Matsuyama,Saori Morino‐Koga,Hironori Adachi,Mary Ann Suico,Junji Kawashima,Hiroyuki Motoshima,Noboru Furukawa,Hirofumi Kai,Eiichi Araki	2012	37
9	The effect of group‐based lifestyle interventions on risk factors and insulin resistance in subjects at risk for metabolic syndrome: the Tabaruzaka Study 1 Diabetes Obesity and Metabolism ·T. Yamashiro,Takeshi Nishikawa,Satoshi Isami,Wei Chen,Kumiko Fukumoto,Hiroshi Matsuo,Tomoyo Yoshinaga,Daisuke Kukidome,Hiroyuki Motoshima,Takeshi Matsumura,Atsushi Ueda,Eiichi Araki	2010	9
10	Oxidized Low Density Lipoprotein Activates Peroxisome Proliferator-activated Receptor-α (PPARα) and PPARγ through MAPK-dependent COX-2 Expression in Macrophages Journal of Biological Chemistry ·Kayo Taketa,Takeshi Matsumura,Miyuki Yano,Norio Ishii,Takafumi Senokuchi,Hiroyuki Motoshima,Yusuke Murata,Shokei Kim‐Mitsuyama,Teruo Kawada,Hiroyuki Itabe,Motohiro Takeya,Takeshi Nishikawa,Kaku Tsuruzoe,Eiichi Araki	2008	58
11	Rottlerin activates AMPK possibly through LKB1 in vascular cells and tissues Biochemical and Biophysical Research Communications ·Kanou Kojima,Hiroyuki Motoshima,Atsuyuki Tsutsumi,Motoyuki Igata,Takeshi Matsumura,Tatsuya Kondo,Junji Kawashima,Kenshi Ichinose,Noboru Furukawa,Kouichi Inukai,Shigehiro Katayama,Barry J. Goldstein,Takeshi Nishikawa,Kaku Tsuruzoe,Eiichi Araki	2008	8
12	Endothelial MnSOD overexpression prevents retinal VEGF expression in diabetic mice Biochemical and Biophysical Research Communications ·Hideo Goto,Takeshi Nishikawa,Kazuhiro Sonoda,Tatsuya Kondo,Daisuke Kukidome,Kazuo Fujisawa,T. Yamashiro,Hiroyuki Motoshima,Takeshi Matsumura,Kaku Tsuruzoe,Eiichi Araki	2007	36
13	Impact of mitochondrial ROS production on diabetic vascular complications Diabetes Research and Clinical Practice ·Takeshi Nishikawa,Daisuke Kukidome,Kazuhiro Sonoda,Kazuo Fujisawa,Takako Matsuhisa,Hiroyuki Motoshima,Takeshi Matsumura,Eiichi Araki	2007	73
14	AICAR, an activator of AMP-activated protein kinase, down-regulates the insulin receptor expression in HepG2 cells Biochemical and Biophysical Research Communications ·Kazuhiko Nakamaru,Kazuya Matsumoto,Tetsuya Taguchi,Mihoshi Suefuji,Yusuke Murata,Motoyuki Igata,Junji Kawashima,Tatsuya Kondo,Hiroyuki Motoshima,Kaku Tsuruzoe,Nobuhiro Miyamura,Tomomi Toyonaga,Eiichi Araki	2005	29
15	Insulin down-regulates resistin mRNA through the synthesis of protein(s) that could accelerate the degradation of resistin mRNA in 3T3-L1 adipocytes Diabetologia ·Junji Kawashima,Kaku Tsuruzoe,Hiroyuki Motoshima,Atsuhisa Shirakami,Koji Sakai,Yoshiaki Hirashima,Tomomi Toyonaga,Eiichi Araki	2003	44
16	Genomic Clones Encoding Two Isoforms of Pokeweed Antiviral Protein in Seeds (PAP-S1 and S2) and the N-Glycosidase Activities of Their Recombinant Proteins on Ribosomes and DNA in Comparison with Other Isoforms The Journal of Biochemistry ·Eijiro Honjo,Danning Dong,Hiroyuki Motoshima,Keiichi Watanabe	2002	19
17	Identification of a cis-Acting Element and a Novel trans-Acting Factor of the Human Insulin Receptor Gene in HepG2 and Rat Liver Cells Biochemical and Biophysical Research Communications ·Kazuaki Yoshizato,T. Shirotani,Noboru Furukawa,Tetsuya Taguchi,Hiroyuki Motoshima,Tomomi Toyonaga,Yoshiaki Hirashima,Junji Kawashima,Yousuke Ebina,Motoaki Shichiri,Eiichi Araki	2001	15
18	Crystal Structure of Rhodopsin: A G Protein-Coupled Receptorbreakdown → Science ·Krzysztof Palczewski,Takashi Kumasaka,Tetsuya Hori,Craig A. Behnke,Hiroyuki Motoshima,Brian A. Fox,Isolde Le Trong,David C. Teller,Tetsuji Okada,Ronald E. Stenkamp,Masaki Yamamoto,Masashi Miyano	2000	4567
19	Involvement of bradykinin in acute exercise-induced increase of glucose uptake and GLUT-4 translocation in skeletal muscle: Studies in normal and diabetic humans and rats Metabolism ·Tetsuya Taguchi,Hideki Kishikawa,Hiroyuki Motoshima,Kohji Sakai,Toshihiko Nishiyama,Kazuaki Yoshizato,Atsuhisa Shirakami,Tomomi Toyonaga,T. Shirotani,Eiichi Araki,Motoaki Shichiri	2000	51
20	Crystal Structure of the Pyridoxal 5'-phosphate Dependent L-Methionine -Lyase from Pseudomonas putida The Journal of Biochemistry ·Hiroyuki Motoshima,Kazumi Inagaki,Takashi Kumasaka,M. Furuichi,Hiroyuki Inoue,Toshiki Tamura,Nobuyoshi Esaki,K. Soda,Nobuo Tanaka,M. Yamamoto,H. Tanaka	2000	44

About Hiroyuki Motoshima

Hiroyuki Motoshima is a scholar working on Aging, Endocrinology, Diabetes and Metabolism and Physiology, having authored 97 papers that have together received 9.7k indexed citations. Recurring topics across this work include Adipose Tissue and Metabolism (22 papers), Metabolism, Diabetes, and Cancer (20 papers), Adipokines, Inflammation, and Metabolic Diseases (15 papers), Enzyme Structure and Function (15 papers), Pancreatic function and diabetes (15 papers), Protein Structure and Dynamics (12 papers), Peroxisome Proliferator-Activated Receptors (10 papers) and Diabetes Treatment and Management (10 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (2.9k citations), Molecular Biology (6.5k citations) and Endocrine and Autonomic Systems (542 citations). Hiroyuki Motoshima has collaborated with scholars based in Japan, United States and China. Frequent co-authors include Barry J. Goldstein, Takashi Kumasaka, Ronald E. Stenkamp, Krzysztof Palczewski, Craig A. Behnke, Tetsuya Hori, David C. Teller, Tetsuji Okada, Brian A. Fox and Masaki Yamamoto. Their work appears in journals such as Science, Journal of Biological Chemistry and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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