Isolde Le Trong

9.1k citations

55 papers · 7.4k indexed · 1 hit paper · h-index 30

Molecular Biology top 1%
Cellular and Molecular Neuroscience top 0.5%
Radiology, Nuclear Medicine and Imaging top 2%
Cell Biology top 2%
Computational Theory and Mathematics top 1%

Co-authors: Ronald E. Stenkamp David C. Teller Krzysztof Palczewski Craig A. Behnke Brian A. Fox Tetsuji Okada Hiroyuki Motoshima Tetsuya Hori
Topics: Biotin and Related Studies (19 papers)Molecular Junctions and Nanostructures (12 papers)Enzyme Structure and Function (9 papers)
Cited by: Cellular and Molecular Neuroscience Molecular Biology Endocrinology
Journals: Science Cell Proceedings of the National Academy of Sciences
Partner nations: United States Switzerland Sweden

In The Last Decade

Isolde Le Trong

55 papers receiving 7.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor

2000 4.6k citations Krzysztof Palczewski, Takashi Kumasaka et al. Science profile →

Peers

Countries citing papers authored by Isolde Le Trong

Since Specialization

Citations

This map shows the geographic impact of Isolde Le Trong's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Isolde Le Trong with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Isolde Le Trong more than expected).

Fields of papers citing papers by Isolde Le Trong

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Isolde Le Trong. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Isolde Le Trong. The network helps show where Isolde Le Trong may publish in the future.

Co-authorship network of co-authors of Isolde Le Trong

This figure shows the co-authorship network connecting the top 25 collaborators of Isolde Le Trong. A scholar is included among the top collaborators of Isolde Le Trong based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Isolde Le Trong. Isolde Le Trong is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The Evolution of SlyA/RovA Transcription Factors from Repressors to Countersilencers in Enterobacteriaceae 2019 ·mBio ·W. Ryan Will,Peter S. Brzović,Isolde Le Trong,Ronald E. Stenkamp,Matthew B. Lawrenz,Joyce E. Karlinsey,William Wiley Navarre,(unknown),Virginia L. Miller,Stephen J. Libby,Ferric C. Fang	22
2	E2~Ub conjugates regulate the kinase activity of Shigella effector OspG during pathogenesis 2014 ·The EMBO Journal ·Jonathan N. Pruneda,F. Donelson Smith,(unknown),Danielle L. Swaney,Judit Villén,John D. Scott,Andrew W. Stadnyk,Isolde Le Trong,Ronald E. Stenkamp,Rachel E. Klevit,John R. Rohde,Peter S. Brzović	58
3	Streptavidin and its biotin complex at atomic resolution 2011 ·Acta Crystallographica Section D Biological Crystallography ·Isolde Le Trong,Zhizhi Wang,David E. Hyre,Terry P. Lybrand,Patrick S. Stayton,Ronald E. Stenkamp	77
4	The Bacterial Fimbrial Tip Acts as a Mechanical Force Sensor 2011 ·PLoS Biology ·Pavel Aprikian,Gianluca Interlandi,Brian Kidd,Isolde Le Trong,Veronika Tchesnokova,Olga Yakovenko,(unknown),Esther Bullitt,Ronald E. Stenkamp,Wendy E. Thomas,Evgeni V. Sokurenko	69
5	Structural Basis for Mechanical Force Regulation of the Adhesin FimH via Finger Trap-like β Sheet Twisting 2010 ·Cell ·Isolde Le Trong,Pavel Aprikian,Brian Kidd,Manu Forero-Shelton,Veronika Tchesnokova,Ponni Rajagopal,(unknown),Gianluca Interlandi,Rachel E. Klevit,Viola Vogel,Ronald E. Stenkamp,Evgeni V. Sokurenko,Wendy E. Thomas	208
6	Donor strand exchange and conformational changes during E. coli fimbrial formation 2010 ·Journal of Structural Biology ·Isolde Le Trong,Pavel Aprikian,Brian Kidd,Wendy E. Thomas,Evgeni V. Sokurenko,Ronald E. Stenkamp	27
7	Cooperative hydrogen bond interactions in the streptavidin–biotin system 2006 ·Protein Science ·David E. Hyre,Isolde Le Trong,E.A. Merritt,John F. Eccleston,(unknown),Ronald E. Stenkamp,Patrick S. Stayton	118
8	Structure of Lmaj006129AAA, a hypothetical protein fromLeishmania major 2006 ·Acta Crystallographica Section F Structural Biology and Crystallization Communications ·T.L. Arakaki,Isolde Le Trong,Eric M. Phizicky,(unknown),George T. DeTitta,Joseph R. Luft,Angela Lauricella,Lori Anderson,Oleksandr Kalyuzhniy,Elizabeth A. Worthey,Peter J. Myler,David E. Kim,David Baker,Wim G. J. Hol,E.A. Merritt	19
9	Crystallographic Analysis of a Full-length Streptavidin with Its C-terminal Polypeptide Bound in the Biotin Binding Site 2005 ·Journal of Molecular Biology ·Isolde Le Trong,Nicolas Humbert,Thomas R. Ward,Ronald E. Stenkamp	28
10	Crystal Structure of a β-Catenin/APC Complex Reveals a Critical Role for APC Phosphorylation in APC Function 2004 ·Molecular Cell ·Yi Xing,Wilson K. Clements,Isolde Le Trong,Thomas R. Hinds,Ronald E. Stenkamp,David Kimelman,Wenqing Xu	134
11	Structural characterization and comparison of RGD cell-adhesion recognition sites engineered into streptavidin 2003 ·Acta Crystallographica Section D Biological Crystallography ·Isolde Le Trong,Todd C. McDevitt,Kjell E. Nelson,Patrick S. Stayton,Ronald E. Stenkamp	16
12	1.3‐Å resolution structure of human glutathione S‐transferase with S‐hexyl glutathione bound reveals possible extended ligandin binding site 2002 ·Proteins Structure Function and Bioinformatics ·Isolde Le Trong,Ronald E. Stenkamp,Catherine Ibarra,William M. Atkins,Elinor T. Adman	54
13	Early mechanistic events in biotin dissociation from streptavidin 2002 ·Nature Structural Biology ·David E. Hyre,Lynn M. Amon,Julie E. Penzotti,Isolde Le Trong,Ronald E. Stenkamp,Terry P. Lybrand,Patrick S. Stayton	45
14	Theoretical and Experimental Studies of Biotin Analogues That Bind Almost as Tightly to Streptavidin as Biotin 2002 ·The Journal of Organic Chemistry ·R. W. Dixon,Randall J. Radmer,Bernd Kuhn,Peter A. Kollman,Jaemoon Yang,César Raposo,Craig S. Wilcox,L.A. Klumb,Patrick S. Stayton,Craig A. Behnke,Isolde Le Trong,Ronald E. Stenkamp	21
15	Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2 2002 ·Protein Science ·Sehat Nauli,Brian Kuhlman,Isolde Le Trong,Ronald E. Stenkamp,David C. Teller,David Baker	48
16	Crystal Structure of Rhodopsin: A G Protein-Coupled Receptorbreakdown → 2000 ·Science ·Krzysztof Palczewski,Takashi Kumasaka,Tetsuya Hori,Craig A. Behnke,Hiroyuki Motoshima,Brian A. Fox,Isolde Le Trong,David C. Teller,Tetsuji Okada,Ronald E. Stenkamp,Masaki Yamamoto,Masashi Miyano	4567
17	Ser45 plays an important role in managing both the equilibrium and transition state energetics of the streptavidin—biotin system 2000 ·Protein Science ·David E. Hyre,Patrick S. Stayton,Isolde Le Trong,Stefanie Freitag,Ronald E. Stenkamp	64
18	Atomic resolution structure of biotin-free Tyr43Phe streptavidin: what is in the binding site? 1999 ·Acta Crystallographica Section D Biological Crystallography ·(unknown),Isolde Le Trong,L.A. Klumb,Patrick S. Stayton,Ronald E. Stenkamp	7
19	X-ray crystallographic studies of streptavidin mutants binding to biotin 1999 ·Biomolecular Engineering ·Stefanie Freitag,Isolde Le Trong,L.A. Klumb,Vano Chu,Ashutosh Chilkoti,Patrick S. Stayton,Ronald E. Stenkamp	29
20	Thermodynamic and structural consequences of flexible loop deletion by circular permutation in the streptavidin‐biotin system 1998 ·Protein Science ·Vano Chu,Patrick S. Stayton,Stefanie Freitag,Isolde Le Trong,Ronald E. Stenkamp	69

About Isolde Le Trong

Isolde Le Trong is a scholar working on Cell Biology, Molecular Medicine and Endocrinology, having authored 55 papers that have together received 7.4k indexed citations. Recurring topics across this work include Biotin and Related Studies (19 papers), Molecular Junctions and Nanostructures (12 papers) and Enzyme Structure and Function (9 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (3.3k citations), Molecular Biology (5.8k citations) and Endocrinology (230 citations). Isolde Le Trong has collaborated with scholars based in United States, Switzerland and Sweden. Frequent co-authors include Ronald E. Stenkamp, David C. Teller, Krzysztof Palczewski, Craig A. Behnke, Brian A. Fox, Tetsuji Okada, Hiroyuki Motoshima, Tetsuya Hori, Takashi Kumasaka and Masashi Miyano. Their work appears in journals such as Science, Cell and Proceedings of the National Academy of Sciences.

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