Hirotoshi Kakuta

643 total citations
25 papers, 531 citations indexed

About

Hirotoshi Kakuta is a scholar working on Molecular Biology, Surgery and Computational Theory and Mathematics. According to data from OpenAlex, Hirotoshi Kakuta has authored 25 papers receiving a total of 531 indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 10 papers in Surgery and 7 papers in Computational Theory and Mathematics. Recurrent topics in Hirotoshi Kakuta's work include Computational Drug Discovery Methods (7 papers), Plant biochemistry and biosynthesis (6 papers) and Cholesterol and Lipid Metabolism (6 papers). Hirotoshi Kakuta is often cited by papers focused on Computational Drug Discovery Methods (7 papers), Plant biochemistry and biosynthesis (6 papers) and Cholesterol and Lipid Metabolism (6 papers). Hirotoshi Kakuta collaborates with scholars based in Japan, Norway and Russia. Hirotoshi Kakuta's co-authors include Tsukasa Ishihara, Hisataka Shikama, Isao Yanagisawa, Keiji Miyata, Motoko Yamaguchi, Toshiyuki Takasu, Osamu Inagaki, Toshiyuki Funatsu, Shintaro Nishimura and Tomotaka Yokoo and has published in prestigious journals such as Biochemical and Biophysical Research Communications, Journal of Pharmacology and Experimental Therapeutics and British Journal of Pharmacology.

In The Last Decade

Hirotoshi Kakuta

25 papers receiving 503 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hirotoshi Kakuta Japan	14	221	155	120	109	64	25	531
Pei-Ran Wang United States	11	271 1.2×	256 1.7×	60 0.5×	129 1.2×	27 0.4×	13	746
J. Prous Spain	12	246 1.1×	100 0.6×	42 0.3×	89 0.8×	71 1.1×	27	665
Benjamin Lauzier France	19	343 1.6×	208 1.3×	237 2.0×	86 0.8×	20 0.3×	64	949
Glenda E. Bilder United States	15	393 1.8×	124 0.8×	144 1.2×	68 0.6×	30 0.5×	26	922
Guowei Zhou China	15	226 1.0×	72 0.5×	34 0.3×	83 0.8×	21 0.3×	44	620
Russell Desnoyer United States	12	323 1.5×	49 0.3×	147 1.2×	60 0.6×	66 1.0×	17	530
Ayumu Yoshikawa Japan	10	254 1.1×	68 0.4×	99 0.8×	96 0.9×	17 0.3×	20	562
Antonio M. Gotto United States	11	272 1.2×	190 1.2×	86 0.7×	169 1.6×	20 0.3×	14	539
Shoji Takakura Japan	16	297 1.3×	169 1.1×	56 0.5×	253 2.3×	22 0.3×	51	803
Hai‐Yan Qian China	11	243 1.1×	52 0.3×	74 0.6×	23 0.2×	30 0.5×	21	547

Countries citing papers authored by Hirotoshi Kakuta

Since Specialization

Citations

This map shows the geographic impact of Hirotoshi Kakuta's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hirotoshi Kakuta with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hirotoshi Kakuta more than expected).

Fields of papers citing papers by Hirotoshi Kakuta

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hirotoshi Kakuta. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hirotoshi Kakuta. The network helps show where Hirotoshi Kakuta may publish in the future.

Co-authorship network of co-authors of Hirotoshi Kakuta

This figure shows the co-authorship network connecting the top 25 collaborators of Hirotoshi Kakuta. A scholar is included among the top collaborators of Hirotoshi Kakuta based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hirotoshi Kakuta. Hirotoshi Kakuta is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Taniguchi, K. & Hirotoshi Kakuta. (2015). Bixalomer, a novel phosphate binder with a small swelling index, improves hyperphosphatemia in chronic kidney disease rat. European Journal of Pharmacology. 766. 129–134. 5 indexed citations

Kakuta, Hirotoshi, Eiji Kurosaki, Tatsuya Niimi, et al.. (2014). Distinct Properties of Telmisartan on Agonistic Activities for Peroxisome Proliferator-Activated Receptor γ among Clinically Used Angiotensin II Receptor Blockers: Drug-Target Interaction Analyses. Journal of Pharmacology and Experimental Therapeutics. 349(1). 10–20. 20 indexed citations

Noda, Akihiro, Hiroshi Fushiki, Yoshihiro Murakami, et al.. (2012). Brain penetration of telmisartan, a unique centrally acting angiotensin II type 1 receptor blocker, studied by PET in conscious rhesus macaques. Nuclear Medicine and Biology. 39(8). 1232–1235. 38 indexed citations

Ohno, Kazuki, Y. Amano, Hirotoshi Kakuta, et al.. (2010). Unique “delta lock” structure of telmisartan is involved in its strongest binding affinity to angiotensin II type 1 receptor. Biochemical and Biophysical Research Communications. 404(1). 434–437. 34 indexed citations

Takasu, Toshiyuki, Hirotoshi Kakuta, Masao Sasamata, & Sho‐ichi Yamagishi. (2006). An Angiotensin II (Ang II) Type 1 Receptor Blocker, Telmisartan, Improves Insulin Resistance in KK-A(y) Diabetic Mice.. PubMed. 2(4). 333–6. 2 indexed citations

Kakuta, Hirotoshi, Toshiyuki Takasu, Masao Sasamata, & Sho‐ichi Yamagishi. (2006). An Angiotensin II (Ang II) Type 1 Receptor Blocker, Telmisartan, Improves Insulin Resistance in KK-Ay Diabetic Mice. International Journal of Biomedical Science. 2(4). 333–336. 2 indexed citations

Kakuta, Hirotoshi, Akimitsu Takahashi, Hitoshi Shimano, et al.. (2005). Effects of Atorvastatin on Glucose Metabolism and Insulin Resistance in KK/Ay Mice. Journal of Atherosclerosis and Thrombosis. 12(2). 77–84. 39 indexed citations

Ishihara, Tsukasa, et al.. (2004). Synthesis and biological evaluation of novel propylamine derivatives as orally active squalene synthase inhibitors. Bioorganic & Medicinal Chemistry. 12(22). 5899–5908. 19 indexed citations

Ishihara, Tsukasa, et al.. (2003). Syntheses of 3-Ethylidenequinuclidine derivatives as squalene synthase inhibitors. Part 2: enzyme inhibition and effects on plasma lipid levels. Bioorganic & Medicinal Chemistry. 11(17). 3735–3745. 10 indexed citations

10.

Kakuta, Hirotoshi, et al.. (2003). YM‐53601, a novel squalene synthase inhibitor, suppresses lipogenic biosynthesis and lipid secretion in rodents. British Journal of Pharmacology. 139(1). 140–146. 15 indexed citations

11.

Ishihara, Tsukasa, et al.. (2003). Syntheses and biological evaluation of novel quinuclidine derivatives as squalene synthase inhibitors. Bioorganic & Medicinal Chemistry. 11(11). 2403–2414. 25 indexed citations

12.

Funatsu, Toshiyuki, Hirotoshi Kakuta, Toshiyuki Takasu, et al.. (2003). Experimental model of postprandial hypertriglyceridemia in sucrose-fed rats and the effectiveness of atorvastatin in the model. Metabolism. 52(5). 609–615. 13 indexed citations

13.

Funatsu, Toshiyuki, Hirotoshi Kakuta, Toshiyuki Takasu, & Keiji Miyata. (2002). Atorvastatin increases hepatic fatty acid beta-oxidation in sucrose-fed rats: comparison with an MTP inhibitor. European Journal of Pharmacology. 455(2-3). 161–167. 16 indexed citations

14.

Kakuta, Hirotoshi, et al.. (2002). Experimental model of escape phenomenon in hamsters and the effectiveness of YM‐53601 in the model. British Journal of Pharmacology. 135(6). 1572–1578. 13 indexed citations

15.

Kakuta, Hirotoshi, et al.. (2002). Effect of YM‐53601, a novel squalene synthase inhibitor, on the clearance rate of plasma LDL and VLDL in hamsters. British Journal of Pharmacology. 137(4). 561–567. 14 indexed citations

16.

Funatsu, Toshiyuki, Hirotoshi Kakuta, Hideyuki Tanaka, et al.. (2001). Atorvastatin (Lipitor<SUP>®</SUP>): a review of its pharmacological and clinical profile. Folia Pharmacologica Japonica. 117(1). 65–76. 7 indexed citations

17.

Kakuta, Hirotoshi, et al.. (2000). YM‐53601, a novel squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in several animal species. British Journal of Pharmacology. 131(1). 63–70. 67 indexed citations

18.

Fan, Jianglin, Masahiro Araki, Lihua Wu, et al.. (1999). Assembly of Lipoprotein (a) in Transgenic Rabbits Expressing Human Apolipoprotein (a). Biochemical and Biophysical Research Communications. 255(3). 639–644. 32 indexed citations

19.

Kashiwa, Makoto, et al.. (1997). Pharmacological Properties of YM17E, an Acyl-CoA:Cholesterol Acyltransferase Inhibitor, and Diarrheal Effect in Beagle Dogs.. The Japanese Journal of Pharmacology. 73(1). 41–50. 14 indexed citations

20.

Kakuta, Hirotoshi. (1978). [Morphological studies on renal changes with age 1. Glomerular, tubular and interstitial changes (author's transl)].. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 20(1). 47–65. 2 indexed citations

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