Y. Amano

1.1k citations

35 papers · 814 · h-index 18

Impact in

Biochemistry top 10%
- Eicosanoids and Hypertension Pharmacology
Computational Theory and Mathematics top 5%
- Computational Drug Discovery Methods

Papers in

Molecular Biology 22
- Phosphodiesterase function and regulation 6
- Biochemical and Molecular Research 5
- Polyamine Metabolism and Applications 4
Pharmacology 8
- Cholinesterase and Neurodegenerative Diseases 6

Co-authors: Takashi Hashimoto (2 shared papers)Yasuyuki Yamada (2 shared papers)Tomohiko Yamaguchi (4 shared papers)Tatsuya Niimi (8 shared papers)Kazuki Ohno (6 shared papers)Masaya Orita (6 shared papers)Hiroko Iwanari (1 shared paper)Asami Hayashi (1 shared paper)
Journals: Bioorganic & Medicinal Chemistry (12 papers)Chemical and Pharmaceutical Bulletin (2 papers)European Journal of Biochemistry (2 papers)Scientific Reports (1 paper)PLANT PHYSIOLOGY (1 paper)
Partner nations: Japan United States Norway

In The Last Decade

Y. Amano

35 papers receiving 786 citations

Peers

Countries citing papers authored by Y. Amano

Since Specialization

Citations

This map shows the geographic impact of Y. Amano's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Y. Amano with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Y. Amano more than expected).

Fields of papers citing papers by Y. Amano

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Y. Amano. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Y. Amano. The network helps show where Y. Amano may publish in the future.

Co-authors

The 25 scholars most cited alongside Y. Amano, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Y. Amano Line = papers co-authored together Y. Amano links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 35 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Hyoscyamine 6β-hydroxylase, an enzyme involved in tropane alkaloid biosynthesis, is localized at the pericycle of the root Journal of Biological Chemistry ·Takashi Hashimoto, Asami Hayashi, Y. Amano, Junko Kohno, Hiroko Iwanari, Sadakazu Usuda, Yasuyuki Yamada	1991	124
2	Species-Dependent Expression of the Hyoscyamine 6[beta]-Hydroxylase Gene in the Pericycle PLANT PHYSIOLOGY ·Takeshi Kanegae, (unknown), Y. Amano, Takashi Hashimoto, Yasuyuki Yamada	1994	67
3	Discovery and structural characterization of peficitinib (ASP015K) as a novel and potent JAK inhibitor Bioorganic & Medicinal Chemistry ·Hisao Hamaguchi, Y. Amano, Ayako Moritomo, Shohei Shirakami, Yutaka Nakajima, Kazuo Nakai, Naoko Nomura, Misato Ito, Yasuyuki Higashi, Takayuki Inoue	2018	66
4	Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells Oncotarget ·Tatsuya Kawase, Taisuke Nakazawa, Tomohiro Eguchi, Hirofumi Tsuzuki, Yoko Ueno, Y. Amano, Tomoyuki Suzuki, Masamichi Mori, Taku Yoshida	2019	58
5	Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography Bioorganic & Medicinal Chemistry ·Y. Amano, Tomohiko Yamaguchi, Eiki Tanabe	2014	45
6	Structural basis for telmisartan-mediated partial activation of PPAR gamma Hypertension Research ·Y. Amano, Tomohiko Yamaguchi, Kazuki Ohno, Tatsuya Niimi, Masaya Orita, Hitoshi Sakashita, Makoto Takeuchi	2012	45
7	Lead Generation and Examples Methods in enzymology on CD-ROM/Methods in enzymology ·Masaya Orita, Kazuki Ohno, Masaichi Warizaya, Y. Amano, Tatsuya Niimi	2011	35
8	Unique “delta lock” structure of telmisartan is involved in its strongest binding affinity to angiotensin II type 1 receptor Biochemical and Biophysical Research Communications ·Kazuki Ohno, Y. Amano, Hirotoshi Kakuta, Tatsuya Niimi, Shoji Takakura, Masaya Orita, Keiji Miyata, Hitoshi Sakashita, Makoto Takeuchi, Issei Komuro, Jitsuo Higaki, Masatsugu Horiuchi, Shokei Kim‐Mitsuyama, Yutaka Mori, Ryuichi Morishita, Sho‐ichi Yamagishi	2010	34
9	Purification and Characterization of an ATP‐dependent Amidohydrolase, N‐methylhydantoin Amidohydrolase, from Pseudomonas putida 77 European Journal of Biochemistry ·Jun Ogawa, Jong Min Kim, Warawadee Nirdnoy, Y. Amano, Hideaki Yamada, Sakayu Shimizu	1995	33
10	Design and synthesis of novel benzimidazole derivatives as phosphodiesterase 10A inhibitors with reduced CYP1A2 inhibition Bioorganic & Medicinal Chemistry ·Wataru Hamaguchi, Naoyuki Masuda, Mai Isomura, Satoshi Miyamoto, Shigetoshi Kikuchi, Y. Amano, Kazuya Honbou, Takuma Mihara, Toshihiro Watanabe	2013	29
11	Novel benzimidazole derivatives as phosphodiesterase 10A (PDE10A) inhibitors with improved metabolic stability Bioorganic & Medicinal Chemistry ·Ayaka Chino, Naoyuki Masuda, Y. Amano, Kazuya Honbou, Takuma Mihara, Mayako Yamazaki, Masaki Tomishima	2014	25
12	Advances in fragment-based drug discovery platforms Expert Opinion on Drug Discovery ·Masaya Orita, Masaichi Warizaya, Y. Amano, Kazuki Ohno, Tatsuya Niimi	2009	25
13	Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2 Bioorganic & Medicinal Chemistry ·Ikumi Kuriwaki, Minoru Kameda, Hiroyuki Hisamichi, Shigetoshi Kikuchi, Kazuhiko Iikubo, Yuichiro Kawamoto, Hiroyuki Moritomo, Yutaka Kondoh, Y. Amano, Y. Tateishi, Yuka Echizen, Yoshinori Iwai, Atsushi Noda, Hiroshi Tomiyama, Tomoyuki Suzuki, Masaaki Hirano	2020	25
14	Structural insights into the novel inhibition mechanism ofTrypanosoma cruzispermidine synthase Acta Crystallographica Section D Biological Crystallography ·Y. Amano, Ichiji Namatame, Y. Tateishi, Kazuya Honboh, Eiki Tanabe, Tatsuya Niimi, Hitoshi Sakashita	2015	21
15	Fragment-Based Discovery of Pyrimido[1,2-<i>b</i>]indazole PDE10A Inhibitors Chemical and Pharmaceutical Bulletin ·Ayaka Chino, Ryushi Seo, Y. Amano, Ichiji Namatame, Wataru Hamaguchi, Kazuya Honbou, Takuma Mihara, Mayako Yamazaki, Masaki Tomishima, Naoyuki Masuda	2018	20
16	Synthesis, SAR study, and biological evaluation of novel quinoline derivatives as phosphodiesterase 10A inhibitors with reduced CYP3A4 inhibition Bioorganic & Medicinal Chemistry ·Wataru Hamaguchi, Naoyuki Masuda, Satoshi Miyamoto, Yasuhiro Shiina, Shigetoshi Kikuchi, Takuma Mihara, Hiroyuki Moriguchi, Hiroshi Fushiki, Yoshihiro Murakami, Y. Amano, Kazuya Honbou, Kouji Hattori	2014	19
17	In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease Scientific Reports ·Ryunosuke Yoshino, Nobuaki Yasuo, Yohsuke Hagiwara, Takashi Ishida, D.K. Inaoka, Y. Amano, Y. Tateishi, Kazuki Ohno, Ichiji Namatame, Tatsuya Niimi, Masaya Orita, Kiyoshi Kita, Yutaka Akiyama, Masakazu Sekijima	2017	19
18	Identification of N-ethylmethylamine as a novel scaffold for inhibitors of soluble epoxide hydrolase by crystallographic fragment screening Bioorganic & Medicinal Chemistry ·Y. Amano, Eiki Tanabe, Tomohiko Yamaguchi	2015	18
19	Discovery and biological evaluation of 1-{2,7-diazaspiro[3.5]nonan-2-yl}prop-2-en-1-one derivatives as covalent inhibitors of KRAS G12C with favorable metabolic stability and anti-tumor activity Bioorganic & Medicinal Chemistry ·Tomoyoshi Imaizumi, Michinori Akaiwa, Tomoaki Abe, Takahiro Nigawara, Takanori Koike, Yoshiki Satake, Kazushi Watanabe, Osamu Kaneko, Y. Amano, Kenichi Mori, Yosuke Yamanaka, Takeyuki Nagashima, Masashi Shimazaki, Kazuyuki Kuramoto	2022	12
20	Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro , and X-ray Crystallography ACS Omega ·Ryunosuke Yoshino, Nobuaki Yasuo, Yohsuke Hagiwara, Takashi Ishida, D.K. Inaoka, Y. Amano, Y. Tateishi, Kazuki Ohno, Ichiji Namatame, Tatsuya Niimi, Masaya Orita, Kiyoshi Kita, Yutaka Akiyama, Masakazu Sekijima	2023	10

About Y. Amano

Y. Amano is a scholar working on Molecular Biology, Pharmacology, Organic Chemistry, Rheumatology and Materials Chemistry, having authored 35 papers that have together received 814 indexed citations. Recurring topics across this work include Phosphodiesterase function and regulation (6 papers), Cholinesterase and Neurodegenerative Diseases (6 papers), Biochemical and Molecular Research (5 papers), Enzyme Structure and Function (4 papers), Polyamine Metabolism and Applications (4 papers), Chemical synthesis and alkaloids (3 papers), Computational Drug Discovery Methods (3 papers) and Trypanosoma species research and implications (3 papers). The work is most often cited by research in Biochemistry (75 citations), Computational Theory and Mathematics (114 citations), Molecular Biology (474 citations), Organic Chemistry (195 citations) and Pharmacology (108 citations). Y. Amano has collaborated with scholars based in Japan, United States and Norway. Frequent co-authors include Takashi Hashimoto, Yasuyuki Yamada, Tomohiko Yamaguchi, Tatsuya Niimi, Kazuki Ohno, Masaya Orita, Hiroko Iwanari, Asami Hayashi, Sadakazu Usuda and Hitoshi Sakashita. Their work appears in journals such as Bioorganic & Medicinal Chemistry, Chemical and Pharmaceutical Bulletin, European Journal of Biochemistry, Scientific Reports and PLANT PHYSIOLOGY.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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