Hilaire C. Lam

5.1k total citations · 1 hit paper
34 papers, 3.8k citations indexed

About

Hilaire C. Lam is a scholar working on Physiology, Molecular Biology and Pulmonary and Respiratory Medicine. According to data from OpenAlex, Hilaire C. Lam has authored 34 papers receiving a total of 3.8k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Physiology, 15 papers in Molecular Biology and 9 papers in Pulmonary and Respiratory Medicine. Recurrent topics in Hilaire C. Lam's work include Tuberous Sclerosis Complex Research (20 papers), Histiocytic Disorders and Treatments (7 papers) and Vascular Tumors and Angiosarcomas (6 papers). Hilaire C. Lam is often cited by papers focused on Tuberous Sclerosis Complex Research (20 papers), Histiocytic Disorders and Treatments (7 papers) and Vascular Tumors and Angiosarcomas (6 papers). Hilaire C. Lam collaborates with scholars based in United States, Italy and China. Hilaire C. Lam's co-authors include Stefan W. Ryter, Augustine M.K. Choi, Seon‐Jin Lee, Hong Pyo Kim, Marlene Rabinovitch, Jeffrey A. Haspel, Katherine A. Fitzgerald, Manuela Cernadas, Vijay Rathinam and Kiichi Nakahira and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Circulation and Nature Communications.

In The Last Decade

Hilaire C. Lam

33 papers receiving 3.7k citations

Hit Papers

1 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

2010 2.5k citations Kiichi Nakahira, Jeffrey A. Haspel et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hilaire C. Lam United States	18	2.3k	1.3k	970	507	474	34	3.8k
Hong Pyo Kim South Korea	7	2.0k 0.9×	1.3k 1.0×	916 0.9×	242 0.5×	371 0.8×	10	3.2k
Matthew D. McGeough United States	21	2.7k 1.2×	1.6k 1.3×	1.2k 1.3×	352 0.7×	253 0.5×	28	4.4k
W. June Brickey United States	32	3.0k 1.3×	932 0.7×	2.5k 2.6×	562 1.1×	285 0.6×	57	5.2k
Herbert J. Zeh United States	16	2.7k 1.2×	2.3k 1.8×	1.1k 1.1×	276 0.5×	898 1.9×	23	5.5k
Chen Yang China	26	1.3k 0.6×	857 0.7×	547 0.6×	246 0.5×	288 0.6×	97	3.3k
Weng-Lang Yang United States	34	1.4k 0.6×	563 0.4×	1.0k 1.1×	313 0.6×	294 0.6×	72	3.0k
Syed R. Ali United States	21	1.9k 0.8×	1.1k 0.8×	1.1k 1.1×	300 0.6×	116 0.2×	35	3.7k
Min Zhu China	35	1.6k 0.7×	756 0.6×	1.1k 1.1×	467 0.9×	220 0.5×	127	4.2k
Anje Cauwels Belgium	27	1.4k 0.6×	551 0.4×	1.3k 1.3×	456 0.9×	234 0.5×	59	3.2k
Derek Strassheim United States	30	1.7k 0.7×	524 0.4×	2.2k 2.2×	436 0.9×	733 1.5×	47	5.1k

Countries citing papers authored by Hilaire C. Lam

Since Specialization

Citations

This map shows the geographic impact of Hilaire C. Lam's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hilaire C. Lam with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hilaire C. Lam more than expected).

Fields of papers citing papers by Hilaire C. Lam

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hilaire C. Lam. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hilaire C. Lam. The network helps show where Hilaire C. Lam may publish in the future.

Co-authorship network of co-authors of Hilaire C. Lam

This figure shows the co-authorship network connecting the top 25 collaborators of Hilaire C. Lam. A scholar is included among the top collaborators of Hilaire C. Lam based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hilaire C. Lam. Hilaire C. Lam is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Dodd, Kayleigh, Hilaire C. Lam, Melissa L. Fishel, et al.. (2022). Drug Inhibition of Redox Factor-1 Restores Hypoxia-Driven Changes in Tuberous Sclerosis Complex 2 Deficient Cells. Cancers. 14(24). 6195–6195. 3 indexed citations

Wang, Ji, Harilaos Filippakis, Heng Du, et al.. (2021). Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells. Proceedings of the National Academy of Sciences. 118(39). 17 indexed citations

Sanin, Andres, Kosmas Kosmas, Ji Wang, et al.. (2021). Therapeutic Targeting of DGKA-Mediated Macropinocytosis Leads to Phospholipid Reprogramming in Tuberous Sclerosis Complex. Cancer Research. 81(8). 2086–2100. 8 indexed citations

Kosmas, Kosmas, Harilaos Filippakis, Damir Khabibullin, et al.. (2021). TSC2 Interacts with HDLBP/Vigilin and Regulates Stress Granule Formation. Molecular Cancer Research. 19(8). 1389–1397. 17 indexed citations

Rehman, Rakhshinda, et al.. (2021). Abstract 14210: Impaired Mitophagy and Reduced Parkin Expression in Human Pulmonary Arterial Smooth Muscle Cells (PASMCs) in Pulmonary Arterial Hypertension (PAH). Circulation. 144(Suppl_1). 1 indexed citations

Kirkpatrick, Jesse D., Ava P. Soleimany, Jaideep S. Dudani, et al.. (2021). Protease activity sensors enable real-time treatment response monitoring in lymphangioleiomyomatosis. European Respiratory Journal. 59(4). 2100664–2100664. 4 indexed citations

Zarei, Mahsa, Heng Du, Amin H. Nassar, et al.. (2019). Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion. The Journal of Experimental Medicine. 216(11). 2635–2652. 17 indexed citations

Liu, Heng-Jia, Hilaire C. Lam, Christian Baglini, et al.. (2019). Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ). Oncogene. 38(49). 7367–7383. 10 indexed citations

Liu, Heng-Jia, Patrick H. Lizotte, Heng Du, et al.. (2018). TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti–PD-1/anti–CTLA-4 immunotherapy. JCI Insight. 3(8). 45 indexed citations

10.

Filippakis, Harilaos, Amine Belaïd, Brian J. Siroky, et al.. (2018). Vps34-mediated macropinocytosis in Tuberous Sclerosis Complex 2-deficient cells supports tumorigenesis. Scientific Reports. 8(1). 14161–14161. 12 indexed citations

11.

Lam, Hilaire C., Christian Baglini, Harilaos Filippakis, et al.. (2017). Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells. Oncotarget. 8(39). 64714–64727. 18 indexed citations

12.

Ren, Siying, Yongfeng Luo, Hui Chen, et al.. (2016). Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization. American Journal Of Pathology. 186(12). 3261–3272. 21 indexed citations

13.

Siempos, Ilias Ι., Hilaire C. Lam, Yan Ding, et al.. (2014). Cecal Ligation and Puncture-induced Sepsis as a Model To Study Autophagy in Mice. Journal of Visualized Experiments. e51066–e51066. 47 indexed citations

14.

Cloonan, Suzanne M., Hilaire C. Lam, Stefan W. Ryter, & Augustine M.K. Choi. (2014). “Ciliophagy”. Autophagy. 10(3). 532–534. 61 indexed citations

15.

Pende, Mario, Ning Liang, Chi Zhang, et al.. (2014). Regulation of YAP by mTOR and autophagy reveals a therapeutic target of Tuberous Sclerosis Complex. The Journal of Cell Biology. 207(1). 2071OIA181–2071OIA181. 6 indexed citations

16.

Ryter, Stefan W., Hilaire C. Lam, Zhi-Hua Chen, & Augustine M.K. Choi. (2011). Deadly triplex: Smoke, autophagy and apoptosis. Autophagy. 7(4). 436–437. 25 indexed citations

17.

Nakahira, Kiichi, Jeffrey A. Haspel, Vijay Rathinam, et al.. (2011). Autophagy Proteins Regulate Innate Immune Response By Inhibiting NALP3 Inflammasome-Mediated Mitochondrial DAN Release. A1077–A1077. 4 indexed citations

18.

Lam, Hilaire C., Augustine M.K. Choi, & Stefan W. Ryter. (2011). Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface. Journal of Visualized Experiments. 49 indexed citations

19.

Chen, Zhi-Hua, Hilaire C. Lam, Yang Jin, et al.. (2010). Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema. Proceedings of the National Academy of Sciences. 107(44). 18880–18885. 310 indexed citations

20.

Lam, Hilaire C., et al.. (2009). Caveolin-1 Protects Against Cigarette Smoking Induced Autophagic Cell Death and Emphysema in Chronic Obstructive Pulmonary Disease.. A1001–A1001. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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