E.F. Pai

17.0k total citations · 5 hit papers
179 papers, 13.1k citations indexed

About

E.F. Pai is a scholar working on Molecular Biology, Materials Chemistry and Oncology. According to data from OpenAlex, E.F. Pai has authored 179 papers receiving a total of 13.1k indexed citations (citations by other indexed papers that have themselves been cited), including 137 papers in Molecular Biology, 72 papers in Materials Chemistry and 24 papers in Oncology. Recurrent topics in E.F. Pai's work include Enzyme Structure and Function (69 papers), Biochemical and Molecular Research (32 papers) and Protein Structure and Dynamics (23 papers). E.F. Pai is often cited by papers focused on Enzyme Structure and Function (69 papers), Biochemical and Molecular Research (32 papers) and Protein Structure and Dynamics (23 papers). E.F. Pai collaborates with scholars based in Canada, Germany and United States. E.F. Pai's co-authors include Wolfgang Kabsch, Georg E. Schulz, Kenneth C. Holmes, B.T. Eger, Takeshi Nishino, Ken Okamoto, Ute Krengel, Dietrich Suck, Hans Georg Mannherz and Tomoko Nishino and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

E.F. Pai

177 papers receiving 12.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Atomic structure of the actin: DNase I complex

1990 1.6k citations E.F. Pai et al. profile →
Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.

1990 939 citations E.F. Pai, Roger S. Goody et al. profile →
Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

1989 758 citations E.F. Pai, Alfred Wittinghofer et al. profile →
Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: Structure-based mechanism of conversion

2000 575 citations B.T. Eger, Ken Okamoto et al. profile →
Crystal structure of metarhodopsin II

2011 550 citations E.F. Pai et al. profile →

Peers

Countries citing papers authored by E.F. Pai

Since Specialization

Citations

This map shows the geographic impact of E.F. Pai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by E.F. Pai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites E.F. Pai more than expected).

Fields of papers citing papers by E.F. Pai

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by E.F. Pai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by E.F. Pai. The network helps show where E.F. Pai may publish in the future.

Co-authorship network of co-authors of E.F. Pai

This figure shows the co-authorship network connecting the top 25 collaborators of E.F. Pai. A scholar is included among the top collaborators of E.F. Pai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with E.F. Pai. E.F. Pai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Defluorination Capability of l‐2‐Haloacid Dehalogenases in the HAD‐Like Hydrolase Superfamily Correlates with Active Site Compactness 2021 ·ChemBioChem ·Peter W. Y. Chan, Nilmadhab Chakrabarti, (unknown), Ondrej Halgas, (unknown), Marielle Aulikki Wälti, (unknown), Christopher Tran, Alexei Savchenko, Alexander F. Yakunin, Elizabeth A. Edwards, Régis Pomès, E.F. Pai	26
2	Substrate-Based Allosteric Regulation of a Homodimeric Enzyme 2019 ·Journal of the American Chemical Society ·P. Mehrabi, (unknown), Tae Hun Kim, Adnan Sljoka, (unknown), Christopher Ing, (unknown), Régis Pomès, E.F. Pai, R. Scott Prosser	35
3	Time-resolved crystallography reveals allosteric communication aligned with molecular breathing 2019 ·Science ·P. Mehrabi, Eike C. Schulz, (unknown), Henrike M. Müller‐Werkmeister, Friedjof Tellkamp, R. J. Dwayne Miller, E.F. Pai	81
4	The role of dimer asymmetry and protomer dynamics in enzyme catalysis 2017 ·Science ·Tae Hun Kim, P. Mehrabi, Zhong Ren, Adnan Sljoka, Christopher Ing, Alexandr Bezginov, Libin Ye, Régis Pomès, R. Scott Prosser, E.F. Pai	141
5	EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis 2016 ·PLoS ONE ·Kevin H.M. Kuo, (unknown), Margaret L. Rand, Hira Mian, (unknown), (unknown), (unknown), Jean‐Philippe Julien, E.F. Pai, Alden Chesney	2
6	Binding to Large Enzyme Pockets: Small‐Molecule Inhibitors of Trypanothione Reductase 2014 ·ChemMedChem ·Elke Persch, S. Bryson, (unknown), Christian Eberle, (unknown), Natalie Dirdjaja, Marcel Kaiser, Maria Weber, (unknown), Reto Brun, Gisbert Schneider, E.F. Pai, R. Luise Krauth‐Siegel, François Diederich	43
7	A Porphodimethene Chemical Inhibitor of Uroporphyrinogen Decarboxylase 2014 ·PLoS ONE ·Kenneth W. Yip, Zhan Zhang, (unknown), Jui-Wen Huang, (unknown), (unknown), Chih‐Lung Lin, Jennifer Kwan, Shi‐Jun Yue, Yulia Jitkova, (unknown), Payam Zahedi, E.F. Pai, Aaron D. Schimmer, Jonathan F. Lovell, Jonathan L. Sessler, Fei‐Fei Liu	3
8	The structure and regulation of magnesium selective ion channels 2013 ·Biochimica et Biophysica Acta (BBA) - Biomembranes ·Jian Payandeh, Roland Pfoh, E.F. Pai	58
9	Computational Design of High-Affinity Epitope Scaffolds by Backbone Grafting of a Linear Epitope 2011 ·Journal of Molecular Biology ·Mihai L. Azoitei, (unknown), Jean‐Philippe Julien, S. Bryson, (unknown), Oleksandr Kalyuzhniy, Justin R. Porter, Yumiko Adachi, David Baker, E.F. Pai, William R. Schief	80
10	Interaction of Anti-HIV Type 1 Antibody 2F5 with Phospholipid Bilayers and Its Relevance for the Mechanism of Virus Neutralization 2010 ·AIDS Research and Human Retroviruses ·(unknown), Nerea Huarte, Jean‐Philippe Julien, Renate Kunert, E.F. Pai, José L. Nieva	11
11	Structural determinants for the inhibitory ligands of orotidine-5′-monophosphate decarboxylase 2010 ·Bioorganic & Medicinal Chemistry ·(unknown), Lianhu Wei, Yan Liu, (unknown), Angélica M. Bello, (unknown), E.F. Pai, Lakshmi P. Kotra	11
12	Crystal Structure of the Complex between the Fab′ Fragment of the Cross-Neutralizing Anti-HIV-1 Antibody 2F5 and the Fab Fragment of Its Anti-idiotypic Antibody 3H6 2008 ·Journal of Molecular Biology ·S. Bryson, Jean‐Philippe Julien, David E. Isenman, Renate Kunert, Hermann Katinger, E.F. Pai	15
13	Inhibition of Orotidine 5-Monophosphate Decarboxylase and Its Therapeutic Potential 2008 ·Mini-Reviews in Medicinal Chemistry ·Lakshmi P. Kotra, (unknown), (unknown), (unknown), (unknown), Angélica M. Bello, E.F. Pai	17
14	Three‐Dimensional Structure and Properties of Wild‐Type and Mutant H‐ ras ‐Encoded p21 2007 ·Novartis Foundation symposium ·Alfred Wittinghofer, Sybille Franken, Axel J. Scheidig, H. Rensland, Alfred Lautwein, E.F. Pai, Roger S. Goody	9
15	Atomic model of human Rcd‐1 reveals an armadillo‐like‐repeat protein with in vitro nucleic acid binding properties 2006 ·Protein Science ·Robert Garces, W. Gillon, E.F. Pai	50
16	Mechanism of the Conversion of Xanthine Dehydrogenase to Xanthine Oxidase 2005 ·Journal of Biological Chemistry ·Tomoko Nishino, Ken Okamoto, Yuko Kawaguchi, Hiroyuki Hori, Tomohiro Matsumura, B.T. Eger, E.F. Pai, Takeshi Nishino	124
17	The structure of OmpF porin in a tetragonal crystal form 1995 ·Structure ·(unknown), R. Michael Garavito, J.N. Jansonius, (unknown), R. Karlsson, (unknown), E.F. Pai, (unknown), (unknown), J.P. Rosenbusch, Gabriele Rummel, Tilman Schirmer	168
18	Time-resolved crystallography on H-ras p21 1992 ·Philosophical Transactions of the Royal Society of London Series A Physical and Engineering Sciences ·Axel J. Scheidig, E.F. Pai, Ilme Schlichting, John E. T. Corrie, G. Reid, Alfred Wittinghofer, Roger S. Goody	12
19	Studies on the structure and mechanism of H-ras p21 1992 ·Philosophical Transactions of the Royal Society B Biological Sciences ·Roger S. Goody, E.F. Pai, Ilme Schlichting, H. Rensland, Axel J. Scheidig, Sybille Franken, Alfred Wittinghofer	34
20	A crystallographic study of the glutathione binding site of glutathione reductase at 0.3‐nm resolution 1989 ·European Journal of Biochemistry ·P. Andrew Karplus, E.F. Pai, Georg E. Schulz	143

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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