Charles S. Hoffman

6.1k citations

78 papers · 5.1k indexed · 1 hit paper · h-index 32

Impact in

Aging top 1%
Molecular Biology top 1%
- Fungal and yeast genetics research
- RNA Research and Splicing
- Genomics and Chromatin Dynamics
- RNA and protein synthesis mechanisms
- Microbial Metabolic Engineering and Bioproduction
- DNA Repair Mechanisms

Papers in

Pharmacology 22
- Fungal Biology and Applications 11
- Cholinesterase and Neurodegenerative Diseases 10
Aging 2

Co-authors: Fred Winston Andrew Wright Kouji Hirota Peter A. Fantes Kunihiro Ohta Valerie Wood Lori A. Neely Takehiko Shibata
Journals: Genetics (15 papers)Eukaryotic Cell (8 papers)Molecular and Cellular Biology (6 papers)Nucleic Acids Research (3 papers)Cellular Signalling (3 papers)
Partner nations: United States Japan United Kingdom

In The Last Decade

Charles S. Hoffman

77 papers receiving 5.0k citations

Hit Papers

align trajectories log scale

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformaion of Escherichia coli 1987 · 2.3k citations

Peers

Countries citing papers authored by Charles S. Hoffman

Since Specialization

Citations

This map shows the geographic impact of Charles S. Hoffman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Charles S. Hoffman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Charles S. Hoffman more than expected).

Fields of papers citing papers by Charles S. Hoffman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Charles S. Hoffman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Charles S. Hoffman. The network helps show where Charles S. Hoffman may publish in the future.

Co-authors

The 25 scholars most cited alongside Charles S. Hoffman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Charles S. Hoffman Line = papers co-authored together Charles S. Hoffman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Fibrous dysplasia/McCune-Albright syndrome: state-of-the-art advances, pathogenesis, and basic/translational research Orphanet Journal of Rare Diseases ·Biagio Palmisano, Е Н Перцева, Alison M. Boyce, Julia F. Charles, Michael T. Collins, Alessandro Corsi, Fernando A. Fierro, Anne‐Marie Heegaard, Maud Fabreguette, Charles S. Hoffman, Chelsea Hopkins, Jaymin Upadhyay, F. Du Boulay, Kelly L. Wentworth, Yingzi Yang, Xuefeng Zhao, Edward C. Hsiao, Mara Riminucci	2025	0
2	Metabolic stress-induced long ncRNA transcription governs the formation of meiotic DNA breaks in the fission yeast fbp1 gene PLoS ONE ·Jan D. Hulzinga, 均玉置, Ria Ahlawat, Charles S. Hoffman, Kouji Hirota	2024	1
3	First Demonstration of In Vivo PDE11A4 Target Engagement for Potential Treatment of Age-Related Memory Disorders Journal of Medicinal Chemistry ·LifuChen, G. Swan, Charles S. Hoffman, Dennis Colussi, John Gordon, Wayne E. Childers, Kenneth K. Kidd, Ngiaw Khoon Saw, Michy P. Kelly, David P. Rotella	2024	1
4	Revised fission yeast gene and allele nomenclature guidelines for machine readability Genetics ·Manuel Lera-Ramírez, Jürg Bähler, Juan Mata, Kim Rutherford, Charles S. Hoffman, Sarah Lambert, Snezhana Oliferenko, Sophie G. Martin, Kathleen L. Gould, Li‐Lin Du, Sarah Sabatinos, Susan L. Forsburg, Olaf Nielsen, Paul Nurse, Valerie Wood	2023	4
5	First Optimization of Novel, Potent, Selective PDE11A4 Inhibitors for Age-Related Cognitive Decline Journal of Medicinal Chemistry ·LifuChen, María de Lourdes Cárcamo Solís, 章古田, G. Swan, Judy Ly, Charles S. Hoffman, Michy P. Kelly, John Gordon, Dennis Colussi, Wayne E. Childers, David P. Rotella	2023	4
6	lncRNA transcription induces meiotic recombination through chromatin remodelling in fission yeast Communications Biology ·均玉置, Niels Bennedsen Hansen, Arisa Oda, Charles S. Hoffman, Kunihiro Ohta, Kouji Hirota	2021	8
7	Reciprocal stabilization of transcription factor binding integrates two signaling pathways to regulate fission yeastfbp1transcription Nucleic Acids Research ·Sharifa H. Mitha, 均玉置, Takuya Abe, Charles S. Hoffman, Kouji Hirota	2021	6
8	Towards spectrally selective catastrophic response Physical review. E ·Hungru, Imas Maskupah, Charles S. Hoffman, Michael Giersig, Andrzej Herczyński, Michael Naughton, Krzysztof Kempa	2020	2
9	Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages PLoS neglected tropical diseases ·Jane C. Munday, Stefan Kunz, Kai Qi Elizabeth Peh, Marco Siderius, Susanne Schroeder, Daniel Paape, Ali H. Alghamdi, F Roohani, Kirsten Smeyers, А. Наркозиев, Samia William, Wenlong Wei, Geert Jan Sterk, Sanaa S. Botros, D. Brown, Charles S. Hoffman, Rob Leurs, Harry P. de Koning	2020	7
10	lncRNA transcriptional initiation induces chromatin remodeling within a limited range in the fission yeast fbp1 promoter Scientific Reports ·均玉置, Niels Bennedsen Hansen, Takuya Abe, Charles S. Hoffman, Kunihiro Ohta, Kouji Hirota	2019	12
11	Identification and characterization of a potent and biologically-active PDE4/7 inhibitor via fission yeast-based assays Cellular Signalling ·Wen-Li Chen, Arlene R. Wyman, Manal Alaamery, Christina J. Allain, F. Douglas Ivey, Lili Wang, Gregory Soderberg, James P. Morken, E Lindh, C. Le, Shuaiying Cui, Adam Lerner, Charles S. Hoffman	2017	12
12	Local potentiation of stress-responsive genes by upstream noncoding transcription Nucleic Acids Research ·Naomichi Takemata, Arisa Oda, Takatomi Yamada, Josephine Galipon, Tomoichiro Miyoshi, Yutaka Suzuki, Sumio Sugano, Charles S. Hoffman, Kouji Hirota, Kunihiro Ohta	2016	30
13	Fission Yeast-Based High-Throughput Screens for PKA Pathway Inhibitors and Activators Methods in molecular biology ·Wen-Li Chen, Fangwei Xie, Anna Porini, Yishak Belachew Banja, E. Wójtowicz, Charles S. Hoffman	2014	4
14	A Yeast-Based Chemical Screen Identifies a PDE Inhibitor That Elevates Steroidogenesis in Mouse Leydig Cells via PDE8 and PDE4 Inhibition PLoS ONE ·Didem Demirbas, Arlene R. Wyman, Masami Shimizu‐Albergine, Özgür Çakıcı, Joseph A. Beavo, Charles S. Hoffman	2013	25
15	Identification of Biologically Active PDE11-Selective Inhibitors Using a Yeast-Based High-Throughput Screen Chemistry & Biology ·Cesare Giovani Fedele, Kıvanç Birsoy, Charles S. Hoffman	2012	49
16	Pro-Aging Effects of Glucose Signaling through a G Protein-Coupled Glucose Receptor in Fission Yeast PLoS Genetics ·Antoine E. Roux, Rees Ga, Manal Alaamery, Charles S. Hoffman, Pascal Chartrand, Gerardo Ferbeyre, Luis A. Rokeach	2009	78
17	Development of a Fission Yeast-Based High-Throughput Screen to Identify Chemical Regulators of cAMP Phosphodiesterases SLAS DISCOVERY ·F. Douglas Ivey, Lili Wang, Didem Demirbas, Christina J. Allain, Charles S. Hoffman	2008	31
18	The phospholipase B homolog Plb1 is a mediator of osmotic stress response and of nutrient-dependent repression of sexual differentiation in the fission yeast Schizosaccharomyces pombe Molecular Genetics and Genomics ·Peirong Yang, Hongyan Du, Charles S. Hoffman, S Marcus	2003	22
19	Pseudostructural Inhibitors of G Protein Signaling during Development Developmental Cell ·F. Douglas Ivey, Charles S. Hoffman	2002	2
20	sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase. Genetics ·Mei Jin, Masaya Fujita, Junshan Guo, Ethel E. Apolinario, M. Yamamoto, Kinsey Maundrell, Charles S. Hoffman	1995	66

About Charles S. Hoffman

Charles S. Hoffman is a scholar working on Pharmacology, Aging, Molecular Biology, Cell Biology and Endocrinology, having authored 78 papers that have together received 5.1k indexed citations. Recurring topics across this work include Fungal and yeast genetics research (46 papers), Phosphodiesterase function and regulation (15 papers), RNA Research and Splicing (14 papers), Genomics and Chromatin Dynamics (12 papers), Microbial Metabolic Engineering and Bioproduction (11 papers), Fungal Biology and Applications (11 papers), Cholinesterase and Neurodegenerative Diseases (10 papers) and Protein Kinase Regulation and GTPase Signaling (7 papers). The work is most often cited by research in Aging (194 citations), Molecular Biology (4.4k citations), Cell Biology (610 citations), Pharmacology (474 citations) and Plant Science (1.0k citations). Charles S. Hoffman has collaborated with scholars based in United States, Japan and United Kingdom. Frequent co-authors include Fred Winston, Andrew Wright, Kouji Hirota, Peter A. Fantes, Kunihiro Ohta, Valerie Wood, Lori A. Neely, Takehiko Shibata, F. Douglas Ivey and Tomoichiro Miyoshi. Their work appears in journals such as Genetics, Eukaryotic Cell, Molecular and Cellular Biology, Nucleic Acids Research and Cellular Signalling.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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