Ralph Holl

1.9k total citations · 1 hit paper
34 papers, 1.5k citations indexed

About

Ralph Holl is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Ralph Holl has authored 34 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 21 papers in Organic Chemistry and 6 papers in Oncology. Recurrent topics in Ralph Holl's work include Carbohydrate Chemistry and Synthesis (8 papers), Pharmacological Receptor Mechanisms and Effects (6 papers) and Antibiotic Resistance in Bacteria (5 papers). Ralph Holl is often cited by papers focused on Carbohydrate Chemistry and Synthesis (8 papers), Pharmacological Receptor Mechanisms and Effects (6 papers) and Antibiotic Resistance in Bacteria (5 papers). Ralph Holl collaborates with scholars based in Germany, France and Japan. Ralph Holl's co-authors include Maria Valeria Raimondi, Dmitrii V. Kalinin, Giovanna Li Petri, Alessandra Montalbano, Virginia Spanò, Paola Barraja, Pil Seok Chae, Ron O. Dror, Joseph A. Lyons and David E. Shaw and has published in prestigious journals such as Nature, Journal of Medicinal Chemistry and Tetrahedron.

In The Last Decade

Ralph Holl

34 papers receiving 1.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structure and function of an irreversible agonist-β2 adrenoceptor complex

2011 643 citations Daniel M. Rosenbaum, Cheng Zhang et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Ralph Holl Germany	15	988	531	377	139	118	34	1.5k
Jesús García Spain	23	1.3k 1.3×	606 1.1×	150 0.4×	132 0.9×	52 0.4×	61	2.2k
Ute A. Hellmich Germany	23	811 0.8×	195 0.4×	133 0.4×	341 2.5×	71 0.6×	77	1.6k
James C. Burnett United States	26	928 0.9×	427 0.8×	222 0.6×	241 1.7×	124 1.1×	57	1.9k
Benjamin D. Madej United States	7	1.1k 1.1×	132 0.2×	209 0.6×	95 0.7×	181 1.5×	7	1.4k
Chia‐Ying Huang Switzerland	19	734 0.7×	130 0.2×	96 0.3×	109 0.8×	48 0.4×	45	1.1k
Krzysztof Rolka Poland	26	1.5k 1.6×	262 0.5×	293 0.8×	268 1.9×	30 0.3×	143	2.1k
N.B. Olivier United States	19	1.0k 1.1×	177 0.3×	383 1.0×	58 0.4×	29 0.2×	23	1.4k
Andrew Fosberry United Kingdom	18	853 0.9×	427 0.8×	127 0.3×	140 1.0×	46 0.4×	26	1.4k
Mattia Sturlese Italy	21	939 1.0×	285 0.5×	102 0.3×	83 0.6×	395 3.3×	85	1.4k
Luke A. Adams Australia	20	509 0.5×	284 0.5×	122 0.3×	78 0.6×	21 0.2×	31	1.1k

Countries citing papers authored by Ralph Holl

Since Specialization

Citations

This map shows the geographic impact of Ralph Holl's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ralph Holl with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ralph Holl more than expected).

Fields of papers citing papers by Ralph Holl

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ralph Holl. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ralph Holl. The network helps show where Ralph Holl may publish in the future.

Co-authorship network of co-authors of Ralph Holl

This figure shows the co-authorship network connecting the top 25 collaborators of Ralph Holl. A scholar is included among the top collaborators of Ralph Holl based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ralph Holl. Ralph Holl is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hoff, Katharina J., Yunqi Li, Jörg Haupenthal, et al.. (2024). Development of Fragment-Based Inhibitors of the Bacterial Deacetylase LpxC with Low Nanomolar Activity. Journal of Medicinal Chemistry. 67(19). 17363–17391. 2 indexed citations

Hoff, Katharina J., Maria Valeria Raimondi, Jelena Melesina, et al.. (2022). Synthesis, biological evaluation, and molecular docking studies of aldotetronic acid-based LpxC inhibitors. Bioorganic Chemistry. 131. 106331–106331. 6 indexed citations

Petri, Giovanna Li, Maria Valeria Raimondi, Virginia Spanò, et al.. (2021). Pyrrolidine in Drug Discovery: A Versatile Scaffold for Novel Biologically Active Compounds. Topics in Current Chemistry. 379(5). 34–34. 161 indexed citations

Petri, Giovanna Li, Virginia Spanò, Ralph Holl, et al.. (2020). Bioactive pyrrole-based compounds with target selectivity. European Journal of Medicinal Chemistry. 208. 112783–112783. 183 indexed citations

Hoff, Katharina J., Sven‐Kevin Hotop, Mark Brönstrup, et al.. (2020). Antibacterial activity of xylose-derived LpxC inhibitors – Synthesis, biological evaluation and molecular docking studies. Bioorganic Chemistry. 107. 104603–104603. 8 indexed citations

Hoff, Katharina J., et al.. (2020). Synthesis and biological evaluation of triazolyl-substituted benzyloxyacetohydroxamic acids as LpxC inhibitors. Bioorganic & Medicinal Chemistry. 28(13). 115529–115529. 10 indexed citations

Marek, Martin, T.B. Shaik, Tino Heimburg, et al.. (2018). Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants. Journal of Medicinal Chemistry. 61(22). 10000–10016. 91 indexed citations

Gabrielli, Valeria, et al.. (2016). Chiral pool synthesis and biological evaluation of C-furanosidic and acyclic LpxC inhibitors. European Journal of Medicinal Chemistry. 110. 340–375. 17 indexed citations

Köhler, Jens, et al.. (2016). Synthesis and biological evaluation of enantiomerically pure glyceric acid derivatives as LpxC inhibitors. Bioorganic & Medicinal Chemistry. 24(5). 1032–1044. 14 indexed citations

10.

Kalinin, Dmitrii V. & Ralph Holl. (2016). Insights into the Zinc-Dependent Deacetylase LpxC: Biochemical Properties and Inhibitor Design. Current Topics in Medicinal Chemistry. 16(21). 2379–2430. 29 indexed citations

11.

Melesina, Jelena, et al.. (2014). Synthesis, biological evaluation and molecular docking studies of benzyloxyacetohydroxamic acids as LpxC inhibitors. Bioorganic & Medicinal Chemistry. 22(3). 1016–1028. 20 indexed citations

12.

Oddo, Alberto, et al.. (2013). Synthesis and biological evaluation of flexible and conformationally constrained LpxC inhibitors. Organic & Biomolecular Chemistry. 11(36). 6056–6056. 31 indexed citations

13.

Fröhlich, Roland, et al.. (2012). Stereocontrolled synthesis of four diastereomeric C-aryl manno- and talofuranosides. Carbohydrate Research. 361. 162–169. 6 indexed citations

14.

Oddo, Alberto & Ralph Holl. (2012). Design and stereoselective synthesis of a C-aryl furanoside as a conformationally constrained CHIR-090 analogue. Carbohydrate Research. 359. 59–64. 25 indexed citations

15.

Rosenbaum, Daniel M., Cheng Zhang, Joseph A. Lyons, et al.. (2011). Structure and function of an irreversible agonist-β2 adrenoceptor complex. Nature. 469(7329). 236–240. 643 indexed citations breakdown →

16.

Holl, Ralph, Bettina Jung, Dirk Schepmann, et al.. (2009). Synthesis and Pharmacological Evaluation of SNC80 Analogues with a Bridged Piperazine Ring. ChemMedChem. 4(12). 2111–2122. 13 indexed citations

17.

Holl, Ralph, et al.. (2009). Structure-Affinity-Relationship Study of Bicyclic σ Receptor Ligands. Central Nervous System Agents in Medicinal Chemistry. 9(3). 220–229. 3 indexed citations

18.

Holl, Ralph, Dirk Schepmann, Patrick J. Bednarski, Renate Grünert, & Bernhard Wünsch. (2009). Relationships between the structure of 6-substituted 6,8-diazabicyclo[3.2.2]nonan-2-ones and their σ receptor affinity and cytotoxic activity. Bioorganic & Medicinal Chemistry. 17(4). 1445–1455. 10 indexed citations

19.

Holl, Ralph, Dirk Schepmann, Renate Grünert, Patrick J. Bednarski, & Bernhard Wünsch. (2008). Relationships between the structure of 6-allyl-6,8-diazabicyclo[3.2.2]nonane derivatives and their σ receptor affinity and cytotoxic activity. Bioorganic & Medicinal Chemistry. 17(2). 777–793. 10 indexed citations

20.

Holl, Ralph, et al.. (2008). Synthesis of 2,5-Diazabicyclo[2.2.2]octanes by Dieckmann Analogous Cyclization. Australian Journal of Chemistry. 61(11). 914–919. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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