Dirk Schepmann

3.9k citations

205 papers · 3.4k indexed · h-index 31

Impact in

Cellular and Molecular Neuroscience top 1%
- Neuroscience and Neuropharmacology Research
- Neuropeptides and Animal Physiology
Organic Chemistry top 1%
- Asymmetric Synthesis and Catalysis
- Axial and Atropisomeric Chirality Synthesis

Papers in ⓘ

Cellular and Molecular Neuroscience 84
- Neuropeptides and Animal Physiology 43
- Neuroscience and Neuropharmacology Research 42
Organic Chemistry 112
- Asymmetric Synthesis and Catalysis 34
- Axial and Atropisomeric Chirality Synthesis 30
- Synthesis of heterocyclic compounds 26

Co-authors: Bernhard Wünsch (194 shared papers)Bastian Frehland (24 shared papers)Kirstin Lehmkuhl (22 shared papers)Roland Fröhlich (16 shared papers)Peter Brust (17 shared papers)Thomas Winckler (4 shared papers)Christian Wiese (10 shared papers)Kenichiro Itami (8 shared papers)
Journals: Bioorganic & Medicinal Chemistry (33 papers)European Journal of Medicinal Chemistry (30 papers)Journal of Medicinal Chemistry (28 papers)ChemMedChem (25 papers)Organic & Biomolecular Chemistry (14 papers)
Partner nations: Germany Italy Switzerland

In The Last Decade

Dirk Schepmann

200 papers receiving 3.4k citations

Peers

Countries citing papers authored by Dirk Schepmann

Since Specialization

Citations

This map shows the geographic impact of Dirk Schepmann's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dirk Schepmann with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dirk Schepmann more than expected).

Fields of papers citing papers by Dirk Schepmann

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dirk Schepmann. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dirk Schepmann. The network helps show where Dirk Schepmann may publish in the future.

Co-authors

The 25 scholars most cited alongside Dirk Schepmann, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Dirk Schepmann Line = papers co-authored together Dirk Schepmann links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 205 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Bivalent β-Carbolines as Potential Multitarget Anti-Alzheimer Agents Journal of Medicinal Chemistry ·Yvonne Rook, Kai-Uwe Schmidtke, Friedemann Gaube, Dirk Schepmann, Bernhard Wünsch, Jörg Heilmann, Jochen Lehmann, Thomas Winckler	2010	122
2	Improvement of σ1 receptor affinity by late-stage C–H-bond arylation of spirocyclic lactones Bioorganic & Medicinal Chemistry ·Christina Meyer, Benedikt Neue, Dirk Schepmann, Shuichi Yanagisawa, Junichiro Yamaguchi, E.‐U. Würthwein, Kenichiro Itami, Bernhard Wünsch	2013	100
3	Quality and Functionality of Saffron: Quality Control, Species Assortment and Affinity of Extract and Isolated Saffron Compounds to NMDA and σ₁(Sigma-1) Receptors Planta Medica ·Matthias Lechtenberg, Dirk Schepmann, Michael Niehues, Nils Hellenbrand, Bernhard Wünsch, Andreas Hensel	2008	80
4	Sila‐Haloperidol, a Silicon Analogue of the Dopamine (D ₂ ) Receptor Antagonist Haloperidol: Synthesis, Pharmacological Properties, and Metabolic Fate ChemMedChem ·Reinhold Tacke, Friedrich Popp, Bárbara Müller, B. Theis, Christian Burschka, Alexandra Hamacher, Matthias U. Kassack, Dirk Schepmann, Bernhard Wünsch, Ulrik Jurva, Eric Wellner	2007	77
5	Synthesis and pharmacological evaluation of like- and unlike-configured tetrahydro-2-benzazepines with the α-substituted benzyl moiety in the 5-position Organic & Biomolecular Chemistry ·Peer Hasebein, Bastian Frehland, Kirstin Lehmkuhl, Roland Fröhlich, Dirk Schepmann, Bernhard Wünsch	2014	69
6	Synthesis and σ receptor affinity of regioisomeric spirocyclic furopyridines European Journal of Medicinal Chemistry ·Kengo Miyata, Dirk Schepmann, Bernhard Wünsch	2014	67
7	Asymmetric Synthesis of 1‐Substituted Tetrahydro‐3‐benzazepines as NMDA Receptor Antagonists European Journal of Organic Chemistry ·Ursula Wirt, Dirk Schepmann, Bernhard Wünsch	2006	64
8	Molecular imaging of σ receptors: synthesis and evaluation of the potent σ1 selective radioligand [18F]fluspidine European Journal of Nuclear Medicine and Molecular Imaging ·Steffen Fischer, Christian Wiese, Eva Große Maestrup, Achim Hiller, Winnie Deuther‐Conrad, Matthias Scheunemann, Dirk Schepmann, Jörg Steinbach, Bernhard Wünsch, Peter Brust	2010	62
9	Development of a selective competitive receptor binding assay for the determination of the affinity to NR2B containing NMDA receptors Journal of Pharmaceutical and Biomedical Analysis ·Dirk Schepmann, Bastian Frehland, Kirstin Lehmkuhl, Bastian Tewes, Bernhard Wünsch	2010	59
10	Conformationally constrained NR2B selective NMDA receptor antagonists derived from ifenprodil: Synthesis and biological evaluation of tetrahydro-3-benzazepine-1,7-diols Bioorganic & Medicinal Chemistry ·Bastian Tewes, Bastian Frehland, Dirk Schepmann, Kai-Uwe Schmidtke, Thomas Winckler, Bernhard Wünsch	2010	55
11	Enantiomerically Pure 1,3-Dioxanes as Highly Selective NMDA and σ₁Receptor Ligands Journal of Medicinal Chemistry ·Jens Köhler, Klaus Bergander, Jörg Fabian, Dirk Schepmann, Bernhard Wünsch	2012	51
12	Natural Product Derived Antiprotozoal Agents: Synthesis, Biological Evaluation, and Structure–Activity Relationships of Novel Chromene and Chromane Derivatives Journal of Medicinal Chemistry ·Dipak Harel, Dirk Schepmann, Helge Prinz, Reto Brun, Thomas J. Schmidt, Bernhard Wünsch	2013	51
13	Pd-Catalyzed Direct C–H Bond Functionalization of Spirocyclic σ₁ Ligands: Generation of a Pharmacophore Model and Analysis of the Reverse Binding Mode by Docking into a 3D Homology Model of the σ₁ Receptor Journal of Medicinal Chemistry ·Christina Meyer, Dirk Schepmann, Shuichi Yanagisawa, Junichiro Yamaguchi, Valentina Dal Col, Erik Laurini, Kenichiro Itami, Sabrina Pricl, Bernhard Wünsch	2012	50
14	Thiophene Bioisosteres of Spirocyclic σ Receptor Ligands. 1. N-Substituted Spiro[piperidine-4,4′-thieno[3,2-c]pyrans] Journal of Medicinal Chemistry ·Christoph Oberdorf, Dirk Schepmann, José Miguel Vela, José Luis Dı́az, Jörg Holenz, Bernhard Wünsch	2008	46
15	Design, Synthesis, and Biological Evaluation of 3‐Benzazepin‐1‐ols as NR2B‐Selective NMDA Receptor Antagonists ChemMedChem ·Bastian Tewes, Bastian Frehland, Dirk Schepmann, Kai‐Uwe Schmidtke, Thomas Winckler, Bernhard Wünsch	2010	45
16	Evaluation of Spirocyclic 3-(3-Fluoropropyl)-2-benzofurans as σ₁ Receptor Ligands for Neuroimaging with Positron Emission Tomography Journal of Medicinal Chemistry ·Eva Große Maestrup, Steffen Fischer, Christian Wiese, Dirk Schepmann, Achim Hiller, Winnie Deuther‐Conrad, Jörg Steinbach, Bernhard Wünsch, Peter Brust	2009	45
17	Synthesis and SAR studies of chiral non-racemic dexoxadrol analogues as uncompetitive NMDA receptor antagonists Bioorganic & Medicinal Chemistry ·Ashutosh Banerjee, Dirk Schepmann, Jens Köhler, E.‐U. Würthwein, Bernhard Wünsch	2010	44
18	The Sigma Enigma:In Vitro/in SilicoSite-Directed Mutagenesis Studies Unveil σ₁Receptor Ligand Binding Biochemistry ·Stefanie Brune, Dirk Schepmann, Karl‐Heinz Klempnauer, Domenico Marson, Valentina Dal Col, Erik Laurini, Maurizio Fermeglia, Bernhard Wünsch, Sabrina Pricl	2014	44
19	Identification of a potent and selective σ1 receptor agonist potentiating NGF-induced neurite outgrowth in PC12 cells Bioorganic & Medicinal Chemistry ·Daniela Rossi, Alice Pedrali, Mariangela Urbano, Raffaella Gaggeri, Massimo Serra, Leyden Fernández, Michael Fernández, Julio Caballero, Simone Ronsisvalle, Orazio Prezzavento, Dirk Schepmann, Bernhard Wuensch, Marco Peviani, Daniela Curti, Ornella Azzolina, Simona Collina	2011	43
20	Synthesis and Pharmacological Characterization of Sila-panamesine, a Sila-Analogue of the σ Receptor Ligand Panamesine (EMD 57445) Organometallics ·Rainer Ilg, Christian Burschka, Dirk Schepmann, Bernhard Wünsch, Reinhold Tacke	2006	41

About Dirk Schepmann

Dirk Schepmann is a scholar working on Cellular and Molecular Neuroscience, Organic Chemistry, Molecular Biology, Biochemistry and Pharmacology, having authored 205 papers that have together received 3.4k indexed citations. Recurring topics across this work include Pharmacological Receptor Mechanisms and Effects (166 papers), Phenothiazines and Benzothiazines Synthesis and Activities (54 papers), Receptor Mechanisms and Signaling (51 papers), Neuropeptides and Animal Physiology (43 papers), Neuroscience and Neuropharmacology Research (42 papers), Asymmetric Synthesis and Catalysis (34 papers), Axial and Atropisomeric Chirality Synthesis (30 papers) and Synthesis of heterocyclic compounds (26 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (1.2k citations), Organic Chemistry (1.6k citations), Molecular Biology (2.4k citations), Biological Psychiatry (61 citations) and Pharmacology (293 citations). Dirk Schepmann has collaborated with scholars based in Germany, Italy and Switzerland. Frequent co-authors include Bernhard Wünsch, Bastian Frehland, Kirstin Lehmkuhl, Roland Fröhlich, Peter Brust, Thomas Winckler, Christian Wiese, Kenichiro Itami, Junichiro Yamaguchi and Erik Laurini. Their work appears in journals such as Bioorganic & Medicinal Chemistry, European Journal of Medicinal Chemistry, Journal of Medicinal Chemistry, ChemMedChem and Organic & Biomolecular Chemistry.

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