Erwin Sigel

10.8k total citations · 3 hit papers
143 papers, 9.0k citations indexed

About

Erwin Sigel is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Plant Science. According to data from OpenAlex, Erwin Sigel has authored 143 papers receiving a total of 9.0k indexed citations (citations by other indexed papers that have themselves been cited), including 110 papers in Molecular Biology, 109 papers in Cellular and Molecular Neuroscience and 15 papers in Plant Science. Recurrent topics in Erwin Sigel's work include Neuroscience and Neuropharmacology Research (97 papers), Nicotinic Acetylcholine Receptors Study (70 papers) and Ion channel regulation and function (39 papers). Erwin Sigel is often cited by papers focused on Neuroscience and Neuropharmacology Research (97 papers), Nicotinic Acetylcholine Receptors Study (70 papers) and Ion channel regulation and function (39 papers). Erwin Sigel collaborates with scholars based in Switzerland, Austria and France. Erwin Sigel's co-authors include Roland Baur, Pari Malherbe, Michael E. Steinmann, Andreas Buhr, Ernesto Carafoli, Eric A. Barnard, Frédéric Minier, Margot Ernst, H Möhler and Cleanthi Mamalaki and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Angewandte Chemie International Edition.

In The Last Decade

Erwin Sigel

143 papers receiving 8.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structure, Function, and Modulation of GABAA Receptors

2012 564 citations Erwin Sigel, Michael E. Steinmann Journal of Biological Chemistry profile →
The benzodiazepine binding site of GABAA receptors

1997 523 citations Erwin Sigel Trends in Pharmacological Sciences profile →
The effect of subunit composition of rat brain GABAA receptors on channel function

1990 512 citations Erwin Sigel, Roland Baur et al. Neuron profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Erwin Sigel Switzerland	51	6.1k	5.8k	836	713	629	143	9.0k
David R. Burt United States	33	6.5k 1.1×	4.8k 0.8×	771 0.9×	299 0.4×	439 0.7×	91	9.0k
Peter J. Flor Switzerland	42	5.6k 0.9×	4.1k 0.7×	1.2k 1.4×	421 0.6×	271 0.4×	86	7.4k
Richard B. Mailman United States	57	5.7k 0.9×	4.8k 0.8×	1.2k 1.4×	234 0.3×	741 1.2×	267	11.1k
Maharaj K. Ticku United States	53	6.6k 1.1×	3.9k 0.7×	1.3k 1.5×	353 0.5×	344 0.5×	188	8.6k
R. W. Olsen United States	35	5.4k 0.9×	3.7k 0.6×	1.1k 1.3×	418 0.6×	219 0.3×	79	7.3k
Ruth M. McKernan United Kingdom	47	6.4k 1.1×	4.5k 0.8×	1.7k 2.0×	316 0.4×	323 0.5×	100	8.5k
Wolfgang Froestl Switzerland	44	5.5k 0.9×	4.3k 0.7×	672 0.8×	263 0.4×	376 0.6×	92	7.3k
S.J. Enna United States	58	6.8k 1.1×	4.7k 0.8×	986 1.2×	534 0.7×	935 1.5×	170	10.1k
H. Steve White United States	64	7.8k 1.3×	5.1k 0.9×	811 1.0×	343 0.5×	957 1.5×	266	13.8k
Waldemar A. Turski Poland	47	5.1k 0.8×	3.0k 0.5×	905 1.1×	224 0.3×	457 0.7×	276	9.3k

Countries citing papers authored by Erwin Sigel

Since Specialization

Citations

This map shows the geographic impact of Erwin Sigel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Erwin Sigel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Erwin Sigel more than expected).

Fields of papers citing papers by Erwin Sigel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Erwin Sigel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Erwin Sigel. The network helps show where Erwin Sigel may publish in the future.

Co-authorship network of co-authors of Erwin Sigel

This figure shows the co-authorship network connecting the top 25 collaborators of Erwin Sigel. A scholar is included among the top collaborators of Erwin Sigel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Erwin Sigel. Erwin Sigel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Steinmann, Michael E., Remo S. Schmidt, Juan P. Macêdo, et al.. (2017). Identification and characterization of the three members of the CLC family of anion transport proteins in Trypanosoma brucei. PLoS ONE. 12(12). e0188219–e0188219. 3 indexed citations

Maldifassi, María C., Roland Baur, & Erwin Sigel. (2016). Functional sites involved in modulation of the GABAA receptor channel by the intravenous anesthetics propofol, etomidate and pentobarbital. Neuropharmacology. 105. 207–214. 54 indexed citations

Fuchs, Alexander, Roland Baur, Clara T. Schoeder, Erwin Sigel, & Christa E. Müller. (2014). Structural analogues of the natural products magnolol and honokiol as potent allosteric potentiators of GABAA receptors. Bioorganic & Medicinal Chemistry. 22(24). 6908–6917. 23 indexed citations

Baur, Roland, Wolfgang Schuehly, & Erwin Sigel. (2014). Moderate concentrations of 4-O-methylhonokiol potentiate GABAA receptor currents stronger than honokiol. Biochimica et Biophysica Acta (BBA) - General Subjects. 1840(10). 3017–3021. 7 indexed citations

Kuhn‐Nentwig, Lucia, I. M. Fedorova, Bernhard Lüscher, et al.. (2012). A Venom-derived Neurotoxin, CsTx-1, from the Spider Cupiennius salei Exhibits Cytolytic Activities. Journal of Biological Chemistry. 287(30). 25640–25649. 32 indexed citations

Stein, Marco, Simon J. Middendorp, Ervin Pejo, et al.. (2012). Azo‐Propofols: Photochromic Potentiators of GABA_AReceptors. Angewandte Chemie International Edition. 51(42). 10500–10504. 118 indexed citations

Steinmann, Michael E., et al.. (2012). myo-Inositol Uptake Is Essential for Bulk Inositol Phospholipid but Not Glycosylphosphatidylinositol Synthesis in Trypanosoma brucei. Journal of Biological Chemistry. 287(16). 13313–13323. 33 indexed citations

Baur, Roland & Erwin Sigel. (2005). Benzodiazepines Affect Channel Opening of GABAA Receptors Induced by Either Agonist Binding Site. Molecular Pharmacology. 67(4). 1005–1008. 26 indexed citations

Sigel, Erwin & Frédéric Minier. (2005). TheXenopus oocyte: System for the study of functional expression and modulation of proteins. Molecular Nutrition & Food Research. 49(3). 228–234. 54 indexed citations

10.

Baur, Roland, Urs Simmen, Martin Senn, Urs Séquin, & Erwin Sigel. (2005). Novel Plant Substances Acting as β Subunit Isoform-Selective Positive Allosteric Modulators of GABAA Receptors. Molecular Pharmacology. 68(3). 787–792. 15 indexed citations

11.

Cope, David W., Peer Wulff, Alessandra Oberto, et al.. (2004). Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor γ2 subunit. Neuropharmacology. 47(1). 17–34. 60 indexed citations

12.

Minier, Frédéric & Erwin Sigel. (2004). Techniques: Use of concatenated subunits for the study of ligand-gated ion channels. Trends in Pharmacological Sciences. 25(9). 499–503. 51 indexed citations

13.

Chen, Lie, Zen Huat Lu, Doris Lang, et al.. (2004). Exon 17 skipping in CLCN1 leads to recessive myotonia congenita. Muscle & Nerve. 29(5). 670–676. 12 indexed citations

14.

Baur, Roland & Erwin Sigel. (2003). On high‐ and low‐affinity agonist sites in GABA_A receptors. Journal of Neurochemistry. 87(2). 325–332. 30 indexed citations

15.

Baur, Roland, et al.. (2002). Forced Subunit Assembly in α1β2γ2 GABAAReceptors. Journal of Biological Chemistry. 277(48). 46020–46025. 226 indexed citations

16.

Baur, Roland, et al.. (2000). Loreclezole as a simple functional marker for homomeric ρ type GABAC receptors. European Journal of Pharmacology. 408(2). R1–R2. 11 indexed citations

17.

Rosen, Glenn D., Erwin Sigel, Gordon F. Sherman, & Albert M. Galaburda. (1995). The neuroprotective effects of MK-801 on the induction of microgyria by freezing injury to the newborn rat neocortex. Neuroscience. 69(1). 107–114. 16 indexed citations

18.

Knoflach, Frédéric, Marika Villa, Stephan Kellenberger, et al.. (1991). The γ3‐subunit of the GABA_A‐receptor confers sensitivity to benzodiazepine receptor ligands. FEBS Letters. 293(1-2). 191–194. 79 indexed citations

19.

Sigel, Erwin, Roland Baur, & Pari Malherbe. (1991). Activation of protein kinase C results in down‐modulation of different recombinant GABA_A‐channels. FEBS Letters. 291(1). 150–152. 104 indexed citations

20.

Sigel, Erwin, Roland Baur, Gerhard Trube, H Möhler, & Pari Malherbe. (1990). The effect of subunit composition of rat brain GABAA receptors on channel function. Neuron. 5(5). 703–711. 512 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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