Emmanuel H. Demont

2.8k citations

42 papers · 891 indexed · h-index 17

Hematology top 5%
- Multiple Myeloma Research and Treatments 11
Organic Chemistry top 10%
- Asymmetric Synthesis and Catalysis 10
- Synthetic Organic Chemistry Methods 8
- Chemical synthesis and alkaloids 6
- Click Chemistry and Applications 4
Molecular Biology
- Protein Degradation and Inhibitors 15
- Ubiquitin and proteasome pathways 7
- Chemical Synthesis and Analysis 4
Pharmacology top 10%
Computational Theory and Mathematics top 5%

Co-authors: Paola Grandi Rab K. Prinjha Chun‐wa Chung Paul Bamborough Robert J. Watson Laurie Gordon M. Petretich Alejandro Pérez‐Luna
Cited by: Hematology Organic Chemistry Molecular Biology
Journals: Angewandte Chemie International Edition (1 paper)Journal of Medicinal Chemistry (9 papers)Journal of Neurochemistry (1 paper)
Partner nations: United Kingdom Germany France

In The Last Decade

Emmanuel H. Demont

40 papers receiving 858 citations

Peers

Countries citing papers authored by Emmanuel H. Demont

Since Specialization

Citations

This map shows the geographic impact of Emmanuel H. Demont's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Emmanuel H. Demont with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Emmanuel H. Demont more than expected).

Fields of papers citing papers by Emmanuel H. Demont

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Emmanuel H. Demont. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Emmanuel H. Demont. The network helps show where Emmanuel H. Demont may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Emmanuel H. Demont, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Emmanuel H. Demont Line = papers co-authored together Emmanuel H. Demont links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structure-Guided Design of a Domain-Selective Bromodomain and Extra Terminal N-Terminal Bromodomain Chemical Probe Journal of Medicinal Chemistry ·Erin K. Bradley,Lucia Fusani,Chun‐wa Chung,Peter D. Craggs,Emmanuel H. Demont,P. G. Humphreys,Darren J. Mitchell,Alex Phillipou,Inmaculada Rioja,Rishi R. Shah,Christopher R. Wellaway,Rab K. Prinjha,David Scott Palmer,William J. Kerr,Marc Reid,Ian D. Wall,Rosa Cookson	2023	6
2	EE563 Cost-Effectiveness of the PPARγ Modulator N-Acetyl-Ged-0507-34-Levo (NAC-GED 5%) Versus Benzoyl Peroxide-Adapalene for Moderate to Severe Acne Value in Health ·Tadeja Matos,M. J. Godbole,A. Grandy,Emmanuel H. Demont,F. Viti,Salvatore Bellinvia,L. Zambeletti,Deshan F. Sebaratnam	2023	1
3	Multigram Synthesis of Tetrasubstituted Dihydrobenzofuran GSK973 Enabled by High-Throughput Experimentation and a Claisen Rearrangement in Flow Organic Process Research & Development ·Catherine M. Alder,Matthew Gray,Chelsea A. Huff,Calvin Manning,Alex Preston,Philip J. Rushworth,Leanna E. Shuster,Robert J. Watson,Katherine M. P. Wheelhouse,Glynn D. Williams,Emmanuel H. Demont	2022	3
4	Domain-selective targeting of BET proteins in cancer and immunological diseases Current Opinion in Chemical Biology ·M. Petretich,Emmanuel H. Demont,Paola Grandi	2020	41
5	Discovery of Tetrahydroquinoxalines as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the Second Bromodomain Journal of Medicinal Chemistry ·Robert P. Law,Stephen J. Atkinson,Paul Bamborough,Chun‐wa Chung,Emmanuel H. Demont,Laurie Gordon,Matthew Lindon,Rab K. Prinjha,Allan J. B. Watson,David J. Hirst	2018	85
6	A Chemical Probe for the ATAD2 Bromodomain Angewandte Chemie ·Paul Bamborough,Chun‐wa Chung,Emmanuel H. Demont,Rebecca C. Furze,Andrew J. Bannister,Ka Hing,Hawa Diallo,Clement Douault,Paola Grandi,Tony Kouzarides,Anne‐Marie Michon,Darren J. Mitchell,Rab K. Prinjha,Christina Rau,Samuel C. Robson,Robert J. Sheppard,Richard J. Upton,Robert J. Watson	2016	10
7	A Chemical Probe for the ATAD2 Bromodomain Angewandte Chemie International Edition ·Paul Bamborough,Chun‐wa Chung,Emmanuel H. Demont,Rebecca C. Furze,Andrew J. Bannister,Ka Hing,Hawa Diallo,Clement Douault,Paola Grandi,Tony Kouzarides,Anne‐Marie Michon,Darren J. Mitchell,Rab K. Prinjha,Christina Rau,Samuel C. Robson,Robert J. Sheppard,Richard J. Upton,Robert J. Watson	2016	51
8	Navigating CYP1A Induction and Arylhydrocarbon Receptor Agonism in Drug Discovery. A Case History with S1P ₁ Agonists Journal of Medicinal Chemistry ·S. Taylor,Emmanuel H. Demont,James R. Gray,Nigel Deeks,Aarti Patel,Dung N. Nguyen,Maxine Taylor,Steve R. Hood,Robert J. Watson,Rino A. Bit,Fiona McClure,Holly Ashall,Jason Witherington	2015	13
9	1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain ACS Medicinal Chemistry Letters ·Emmanuel H. Demont,Paul Bamborough,Chun‐wa Chung,Peter D. Craggs,David J. Fallon,Laurie Gordon,Paola Grandi,Clare I. Hobbs,Jameed Hussain,Emma J. Jones,Armelle Le Gall,Anne‐Marie Michon,Darren J. Mitchell,Rab K. Prinjha,Andy D. Roberts,Robert J. Sheppard,Robert J. Watson	2014	68
10	The utility of pharmacokinetic–pharmacodynamic modeling in the discovery and optimization of selective S1P₁agonists Xenobiotica ·S. Taylor,James R. Gray,Robert Willis,Nigel Deeks,Andrea Haynes,Colin A. Campbell,Pam Gaskin,Karen Leavens,Emmanuel H. Demont,Simon J. Dowell,Jenni Cryan,Mary A. Morse,Aarti Patel,Helen Garden,Jason Witherington	2012	4
11	Synthesis and structure–activity relationships of a series of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor Bioorganic & Medicinal Chemistry Letters ·Laura J. Chambers,Alexander J. Stevens,Andrew P. Moses,Anton D. Michel,Daryl S. Walter,D.J.G. Davies,David G. Livermore,Elena Fonfría,Emmanuel H. Demont,Mythily Vimal,Pam Theobald,Paul Beswick,Robert J. Gleave,Shilina Roman,Stefan Senger	2010	21
12	Asymmetric Total Synthesis of (+)‐6‐epi‐Castanospermine by the Stereoselective Formation of a syn,anti Acetylenic 2‐Amino‐1,3‐diol Stereotriad European Journal of Organic Chemistry ·Julien Louvel,Candice Botuha,Fabrice Chemla,Emmanuel H. Demont,Franck Ferreira,Alejandro Pérez‐Luna	2010	29
13	Discovery of biaryl inhibitors of H+/K+ ATPase Bioorganic & Medicinal Chemistry Letters ·Neil Garton,Nick Bailey,Mark J. Bamford,Emmanuel H. Demont,Irene Farre-Gutierrez,Gail Hutley,Gianpaolo Bravi,Paula M. Pickering	2009	8
14	Orally active C-6 heteroaryl- and heterocyclyl-substituted imidazo[1,2-a]pyridine acid pump antagonists (APAs) Bioorganic & Medicinal Chemistry Letters ·Nick Bailey,Mark J. Bamford,Delphine Brissy,Joanna Brookfield,Emmanuel H. Demont,Richard L. Elliott,Neil Garton,Irene Farre-Gutierrez,Thomas G. Hayhow,Gail Hutley,A. Naylor,Terry A. Panchal,Hui-Xian Seow,David J. Spalding,Andrew K. Takle	2009	12
15	Evaluation of basic, heterocyclic ring systems as templates for use as potassium competitive acid blockers (pCABs) Bioorganic & Medicinal Chemistry Letters ·Terry Panchal,Nick Bailey,Mark J. Bamford,Emmanuel H. Demont,Richard L. Elliott,Irene Farre-Gutierrez,Neil Garton,Thomas G. Hayhow,Gail Hutley,A. Naylor	2009	10
16	Synthesis of Indoles: Efficient Functionalization of the 7‐Position. ChemInform ·Nicolas Charrier,Emmanuel H. Demont,R. Dunsdon,G. Maile,Alan Naylor,Alistair O’Brien,Sally Redshaw,Pam Theobald,D. Vesey,Daryl S. Walter	2007	1
17	Oral administration of a potent and selective non‐peptidic BACE‐1 inhibitor decreases β‐cleavage of amyloid precursor protein and amyloid‐β production in vivo Journal of Neurochemistry ·Ishrut Hussain,Julie A. Hawkins,David C. Harrison,Christopher J. Hille,Gareth Wayne,Leanne Cutler,Tania Buck,Daryl S. Walter,Emmanuel H. Demont,Colin Howes,Alan Naylor,Philip Jeffrey,María Isabel González,Colin Dingwall,Anton D. Michel,Sally Redshaw,John B. Davis	2006	133
18	Synthesis of Indoles: Efficient Functionalisation of the 7-Position Synthesis ·Emmanuel H. Demont,Nicolas Charrier,R. Dunsdon,G. Maile,Alan Naylor,A. S. O'Brien,Sally Redshaw,Pam Theobald,D. Vesey,Daryl S. Walter	2006	4
19	HIV Protease Inhibitors Part 2: [3+2] Cycloaddition, Isomerization; and Ring Expansion en route to 4,5-Substituted Cyclohexenones Synlett ·Emmanuel H. Demont,Andrew J. Eatherton,Christopher S. Frampton,Irfan Kahn,Sally Redshaw	2004	6
20	Enantioselective Synthesis of the C1−C11 Fragment of Bafilomycin A₁Using Non-Wittig and Desymmetrization Strategies The Journal of Organic Chemistry ·Jean‐Christophe Poupon,Emmanuel H. Demont,Joëlle Prunet,Jean‐Pierre Férézou	2003	16

About Emmanuel H. Demont

Emmanuel H. Demont is a scholar working on Hematology, Organic Chemistry and Molecular Biology, having authored 42 papers that have together received 891 indexed citations. Recurring topics across this work include Protein Degradation and Inhibitors (15 papers), Multiple Myeloma Research and Treatments (11 papers), Asymmetric Synthesis and Catalysis (10 papers), Synthetic Organic Chemistry Methods (8 papers), Ubiquitin and proteasome pathways (7 papers), Chemical synthesis and alkaloids (6 papers), Click Chemistry and Applications (4 papers) and Chemical Synthesis and Analysis (4 papers). The work is most often cited by research in Hematology (229 citations), Organic Chemistry (322 citations) and Molecular Biology (527 citations). Emmanuel H. Demont has collaborated with scholars based in United Kingdom, Germany and France. Frequent co-authors include Paola Grandi, Rab K. Prinjha, Chun‐wa Chung, Paul Bamborough, Robert J. Watson, Laurie Gordon, M. Petretich, Alejandro Pérez‐Luna, Julien Louvel and Fabrice Chemla. Their work appears in journals such as Angewandte Chemie International Edition, Journal of Medicinal Chemistry and Journal of Neurochemistry.

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