David J. Spalding

702 citations

21 papers · 579 indexed · h-index 13

Co-authors: Anders Rane Beverley Hammond Margarita G. Ladona Scott Summerfield Meindert Danhof Oscar Della Pasqua Dymphy Huntjens Alexander J. Stevens
Topics: Inflammatory mediators and NSAID effects (10 papers)Pharmacogenetics and Drug Metabolism (7 papers)Drug Transport and Resistance Mechanisms (4 papers)
Cited by: Pharmacology Pharmaceutical Science
Journals: Journal of Pharmacology and Experimental Therapeutics British Journal of Pharmacology Biochemical Pharmacology
Partner nations: United Kingdom Netherlands Sweden

In The Last Decade

David J. Spalding

21 papers receiving 550 citations

Peers

Countries citing papers authored by David J. Spalding

Since Specialization

Citations

This map shows the geographic impact of David J. Spalding's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David J. Spalding with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David J. Spalding more than expected).

Fields of papers citing papers by David J. Spalding

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David J. Spalding. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David J. Spalding. The network helps show where David J. Spalding may publish in the future.

Co-authorship network of co-authors of David J. Spalding

This figure shows the co-authorship network connecting the top 25 collaborators of David J. Spalding. A scholar is included among the top collaborators of David J. Spalding based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David J. Spalding. David J. Spalding is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Discovery of {4-[4,9-bis(ethyloxy)-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl]-2-fluorophenyl}acetic acid (GSK726701A), a novel EP4 receptor partial agonist for the treatment of pain 2018 ·Bioorganic & Medicinal Chemistry Letters ·Mark P. Healy,(unknown),(unknown),Andy Billinton,Iain P. Chessell,(unknown),Gerard M.P. Giblin,(unknown),(unknown),Anton D. Michel,Alan Naylor,(unknown),David J. Spalding,David A. Stevens,Martin E. Swarbrick,(unknown)	4
2	Impact of chronic inflammation on the pharmacokinetic–pharmacodynamic relationship of naproxen 2009 ·European Journal of Pain ·Dymphy Huntjens,David J. Spalding,Meindert Danhof,Oscar Della Pasqua	5
3	Orally active C-6 heteroaryl- and heterocyclyl-substituted imidazo[1,2-a]pyridine acid pump antagonists (APAs) 2009 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Mark J. Bamford,(unknown),(unknown),Emmanuel H. Demont,Richard L. Elliott,Neil Garton,(unknown),Thomas G. Hayhow,(unknown),A. Naylor,(unknown),(unknown),David J. Spalding,Andrew K. Takle	12
4	Population pharmacokinetic modelling of the enterohepatic recirculation of diclofenac and rofecoxib in rats 2008 ·British Journal of Pharmacology ·Dymphy Huntjens,(unknown),Anne Chain,(unknown),Scott Summerfield,David J. Spalding,Meindert Danhof,Oscar Della Pasqua	24
5	Differences in the sensitivity of behavioural measures of pain to the selectivity of cyclo‐oxygenase inhibitors 2008 ·European Journal of Pain ·Dymphy Huntjens,David J. Spalding,Meindert Danhof,Oscar Della Pasqua	22
6	1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists: Structure–activity relationships of 4- and 5-substituted benzoic acid derivatives 2006 ·Bioorganic & Medicinal Chemistry Letters ·Adrian Hall,Susan H. Brown,Iain P. Chessell,A. R. Chowdhury,(unknown),Tanya Coleman,Gerard M.P. Giblin,Beverley Hammond,Mark P. Healy,Matthew R. Johnson,(unknown),Anton D. Michel,Alan Naylor,Riccardo Novelli,David J. Spalding,(unknown)	9
7	Correlation betweenin vitroandin vivoconcentration–effect relationships of naproxen in rats and healthy volunteers 2006 ·British Journal of Pharmacology ·Dymphy Huntjens,David J. Spalding,Meindert Danhof,Oscar Della Pasqua	34
8	Structure–activity relationships of 1,5-biaryl pyrroles as EP1 receptor antagonists 2006 ·Bioorganic & Medicinal Chemistry Letters ·Adrian Hall,Stephen J. Atkinson,Susan H. Brown,Iain P. Chessell,A. R. Chowdhury,(unknown),Tanya Coleman,Gerard M.P. Giblin,Robert J. Gleave,Beverley Hammond,Mark P. Healy,Matthew R. Johnson,Anton D. Michel,Alan Naylor,Riccardo Novelli,David J. Spalding,(unknown)	21
9	Discovery of novel biaryl heterocyclic EP1 receptor antagonists 2006 ·Bioorganic & Medicinal Chemistry Letters ·Adrian Hall,Rino A. Bit,Susan H. Brown,(unknown),Iain P. Chessell,Tanya Coleman,Gerard M.P. Giblin,David N. Hurst,(unknown),Xiao Qing Lewell,Anton D. Michel,(unknown),Alan Naylor,Riccardo Novelli,(unknown),David J. Spalding,(unknown),Richard J. Wilson	16
10	Improving the in Vitro Prediction of in Vivo Central Nervous System Penetration: Integrating Permeability, P-glycoprotein Efflux, and Free Fractions in Blood and Brain 2006 ·Journal of Pharmacology and Experimental Therapeutics ·Scott Summerfield,Alexander J. Stevens,Leanne Cutler,(unknown),Beverley Hammond,Sac-Pham Tang,Anne Hersey,David J. Spalding,Phil Jeffrey	138
11	1,5-Biaryl pyrrole derivatives as EP1 receptor antagonists. Structure–activity relationships of 6-substituted and 5,6-disubstituted benzoic acid derivatives 2006 ·Bioorganic & Medicinal Chemistry Letters ·Adrian Hall,Susan H. Brown,Iain P. Chessell,A. R. Chowdhury,(unknown),Tanya Coleman,Gerard M.P. Giblin,Beverley Hammond,Mark P. Healy,Matthew R. Johnson,(unknown),Anton D. Michel,Alan Naylor,Riccardo Novelli,David J. Spalding,(unknown),(unknown)	12
12	The discovery of 6-[2-(5-chloro-2-{[(2,4-difluorophenyl)methyl]oxy}phenyl)-1-cyclopenten-1-yl]-2-pyridinecarboxylic acid, GW848687X, a potent and selective prostaglandin EP1 receptor antagonist for the treatment of inflammatory pain 2006 ·Bioorganic & Medicinal Chemistry Letters ·Gerard M.P. Giblin,Rino A. Bit,Susan H. Brown,(unknown),A. R. Chowdhury,Iain P. Chessell,(unknown),Tanya Coleman,Adrian Hall,Beverley Hammond,David N. Hurst,Anton D. Michel,Alan Naylor,Riccardo Novelli,Tiziana Scoccitti,David J. Spalding,(unknown),Alex Wilson,(unknown)	42
13	Pyridone derivatives as potent, orally bioavailable VLA-4 integrin antagonists 2006 ·Bioorganic & Medicinal Chemistry Letters ·Jason Witherington,(unknown),Vincent Bordas,Richard L. Elliott,Alessandra Gaiba,Neil Garton,(unknown),A. Naylor,David G. Smith,David J. Spalding,Andrew K. Takle,Robert W. Ward	6
14	Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and c-erbB-2 2001 ·Bioorganic & Medicinal Chemistry Letters ·Stuart Cockerill,Colin Stubberfield,Jeremy N. Stables,(unknown),Stephen B. Guntrip,Kathryn J. Smith,(unknown),Robert J. Shaw,Peter Topley,Lindy L. Thomsen,Karen Affleck,Amanda Jowett,D. Neil Hayes,(unknown),P.M. Woollard,David J. Spalding	63
15	Combining high-throughput pharmacokinetic screens at the hits-to-leads stage of drug discovery 2000 ·Drug Discovery Today ·David J. Spalding,(unknown),Martin K. Bayliss	9
16	Evaluation of pyrazole and ethanol induced S9 fraction in bacterial mutagenicity testing 1994 ·Mutagenesis ·Dermot Burke,(unknown),(unknown),Martin K. Bayliss,David J. Spalding,Philip E. Wilcox	26
17	Glucuronidation of Morphine and some Drug Oxidation Reactions in Liver Microsomes from Pregnant and Non‐Pregnant Rhesus Monkeys 1991 ·Pharmacology & Toxicology ·Eva Gerdin,David J. Spalding,Bo Lindberg,Anders Rane	2
18	Polymorphic formation of morphine from codeine in poor and extensive metabolizers of dextromethorphan: Relationship to the presence of immunoidentified cytochrome P-450IID1 1990 ·Clinical Pharmacology & Therapeutics ·(unknown),Kerstin Persson Waye,Margarita G. Ladona,David J. Spalding,(unknown),Urs Meyer,Anders Rane	71
19	Determination of codeine and its metabolites in human blood plasma and in microsomal incubates by high-performance liquid chromatography with ultraviolet detection 1989 ·Journal of Chromatography B Biomedical Sciences and Applications ·(unknown),Björn Lindström,David J. Spalding,Agneta Wahlström,Anders Rane	16
20	Human fetal and adult liver metabolism of ethylmorphine 1989 ·Biochemical Pharmacology ·Margarita G. Ladona,David J. Spalding,Lena Ekman,(unknown),Anders Rane	43

About David J. Spalding

David J. Spalding is a scholar working on Pharmacology, Pharmacology and Organic Chemistry, having authored 21 papers that have together received 579 indexed citations. Recurring topics across this work include Inflammatory mediators and NSAID effects (10 papers), Pharmacogenetics and Drug Metabolism (7 papers) and Drug Transport and Resistance Mechanisms (4 papers). The work is most often cited by research in Pharmacology (169 citations), Pharmacology (138 citations) and Pharmaceutical Science (43 citations). David J. Spalding has collaborated with scholars based in United Kingdom, Netherlands and Sweden. Frequent co-authors include Anders Rane, Beverley Hammond, Margarita G. Ladona, Scott Summerfield, Meindert Danhof, Oscar Della Pasqua, Dymphy Huntjens, Alexander J. Stevens, Sac-Pham Tang and Leanne Cutler. Their work appears in journals such as Journal of Pharmacology and Experimental Therapeutics, British Journal of Pharmacology and Biochemical Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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