Elizabeth Brigham

2.4k total citations
22 papers, 1.6k citations indexed

About

Elizabeth Brigham is a scholar working on Physiology, Molecular Biology and Cellular and Molecular Neuroscience. According to data from OpenAlex, Elizabeth Brigham has authored 22 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Physiology, 9 papers in Molecular Biology and 4 papers in Cellular and Molecular Neuroscience. Recurrent topics in Elizabeth Brigham's work include Alzheimer's disease research and treatments (11 papers), Parkinson's Disease Mechanisms and Treatments (4 papers) and Cholinesterase and Neurodegenerative Diseases (3 papers). Elizabeth Brigham is often cited by papers focused on Alzheimer's disease research and treatments (11 papers), Parkinson's Disease Mechanisms and Treatments (4 papers) and Cholinesterase and Neurodegenerative Diseases (3 papers). Elizabeth Brigham collaborates with scholars based in United States, Canada and Germany. Elizabeth Brigham's co-authors include Russell E. Rydel, Sarah Wright, Mark Wogulis, Steven Estus, H. Michael Tucker, Patrick C. May, Linda K. Simmons, Ivan Lieberburg, K J Tomaselli and David N. Brems and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Neuroscience and PLoS ONE.

In The Last Decade

Elizabeth Brigham

22 papers receiving 1.6k citations

Peers

Countries citing papers authored by Elizabeth Brigham

Since Specialization

Citations

This map shows the geographic impact of Elizabeth Brigham's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Elizabeth Brigham with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Elizabeth Brigham more than expected).

Fields of papers citing papers by Elizabeth Brigham

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Elizabeth Brigham. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Elizabeth Brigham. The network helps show where Elizabeth Brigham may publish in the future.

Co-authorship network of co-authors of Elizabeth Brigham

This figure shows the co-authorship network connecting the top 25 collaborators of Elizabeth Brigham. A scholar is included among the top collaborators of Elizabeth Brigham based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Elizabeth Brigham. Elizabeth Brigham is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Pharmacokinetic/Pharmacodynamic Correlation Analysis of Amantadine for Levodopa-Induced Dyskinesia 2018 ·Journal of Pharmacology and Experimental Therapeutics ·Elizabeth Brigham, Tom H. Johnston, (unknown), Jonathon Holt, Susan H. Fox, Michael P. Hill, Patrick A. Howson, Jonathan M. Brotchie, Jack Nguyen	21
2	Pharmacokinetic/Pharmacodynamic Analysis of Amantadine for Levodopa-Induced Dyskinesia: Correlation of Therapeutic Plasma Concentrations from Multiple Species with Humans (S45.006) 2018 ·Neurology ·Elizabeth Brigham, Tom H. Johnston, (unknown), Jonathon Holt, Susan H. Fox, Patrick A. Howson, Jonathan M. Brotchie, Jack Nguyen	1
3	Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome 2015 ·Neurobiology of Disease ·Andrea Giacomini, Fiorenza Stagni, Stefania Trazzi, Sandra Guidi, Marco Emili, Elizabeth Brigham, Elisabetta Ciani, Renata Bartesaghi	35
4	Discovery of 4-alkylamino-7-aryl-3-cyanoquinoline LRRK2 kinase inhibitors 2013 ·Bioorganic & Medicinal Chemistry Letters ·Albert W. Garofalo, Marc Adler, Danielle L. Aubele, Elizabeth Brigham, David Chian, Maurizio Franzini, Erich Goldbach, (unknown), Ruth Motter, Gary D. Probst, Kevin P. Quinn, Lany Ruslim, Hing L. Sham, Danny Tam, (unknown), Anh P. Truong, (unknown), Zhao Ren	23
5	Leucine-Rich Repeat Kinase 2 (LRRK2)-Deficient Rats Exhibit Renal Tubule Injury and Perturbations in Metabolic and Immunological Homeostasis 2013 ·PLoS ONE ·Daniel Ness, Zhao Ren, Shyra J. Gardai, (unknown), Victor J. Johnson, Richard Brennan, Elizabeth Brigham, Andrew Olaharski	65
6	The beta-secretase-derived C-terminal fragment of APP (C99): a key determinant for intraneuronal pathology in the 3xTgAD mouse 2013 ·Molecular Neurodegeneration ·Inger Lauritzen, Raphaëlle Pardossi‐Piquard, (unknown), Elizabeth Brigham, (unknown), (unknown), L. Chami, Julie Dunys, Frédéric Checler	1
7	Development of ALZET® osmotic pump compatible solvent compositions to solubilize poorly soluble compounds for preclinical studies 2012 ·Drug Delivery ·Rampurna Prasad Gullapalli, (unknown), Elizabeth Brigham, (unknown), (unknown), C O Willits, (unknown), Erich Goldbach, (unknown)	13
8	The β-Secretase-Derived C-Terminal Fragment of βAPP, C99, But Not Aβ, Is a Key Contributor to Early Intraneuronal Lesions in Triple-Transgenic Mouse Hippocampus 2012 ·Journal of Neuroscience ·Inger Lauritzen, Raphaëlle Pardossi‐Piquard, Charlotte Bauer, Elizabeth Brigham, Jean-Daniel Abraham, (unknown), Paul Fraser, Peter St George‐Hyslop, Ophélia Le Thuc, (unknown), L. Chami, Julie Dunys, Frédéric Checler	158
9	Amino-caprolactam γ-secretase inhibitors showing potential for the treatment of Alzheimer’s disease 2011 ·Bioorganic & Medicinal Chemistry Letters ·Martin L. Neitzel, Danielle L. Aubele, (unknown), Jacek Jagodziński, Andrei W. Konradi, Michael A. Pleiss, Balázs Szőke, Wes Zmolek, Erich Goldbach, (unknown), John‐Michael Sauer, Elizabeth Brigham, William H. Wallace, Michael P. Bova, (unknown), Guriqbal S. Basi	4
10	Discovery of a novel sulfonamide-pyrazolopiperidine series as potent and efficacious γ-secretase inhibitors (Part II) 2010 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Andrei W. Konradi, (unknown), Danielle L. Aubele, Albert W. Garofalo, (unknown), (unknown), (unknown), Hing L. Sham, (unknown), Anh P. Truong, Jing Wu, Hongbin Zhang, Erich Goldbach, John‐Michael Sauer, Elizabeth Brigham, Michael P. Bova, Guriqbal S. Basi	12
11	Discovery of a novel sulfonamide-pyrazolopiperidine series as potent and Efficacious γ-Secretase Inhibitors 2010 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Andrei W. Konradi, (unknown), Ying‐zi Xu, (unknown), Albert W. Garofalo, (unknown), Hing L. Sham, Anh P. Truong, Jacek Jagodziński, Michael A. Pleiss, Hongbin Zhang, Erich Goldbach, John‐Michael Sauer, Elizabeth Brigham, Michael P. Bova, Guriqbal S. Basi	14
12	Discovery of sulfonamide–pyrazole γ-secretase inhibitors 2010 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Martin L. Neitzel, David A. Quincy, (unknown), Albert W. Garofalo, Pamela S. Keim, Andrei W. Konradi, Michael A. Pleiss, Hing L. Sham, Elizabeth Brigham, Erich Goldbach, Hongbin Zhang, John‐Michael Sauer, Guriqbal S. Basi	13
13	P3‐321: APP‐selective gamma secretase inhibitor ELND006 effects on brain parenchymal and vascular amyloid beta in the PDAPP mouse model of Alzheimer's disease 2010 ·Alzheimer s & Dementia ·Sally Schroeter, Elizabeth Brigham, Ruth Motter, (unknown), Terry Guido, Karen Khan, Dora Kholodenko, (unknown), Ferdie Soriano, Kevin P. Quinn, Erich Goldbach, Dora Games, Daniel Ness	3
14	P3‐322: Effects of single and multiple dose oral administration of ELND006, a novel APP‐selective gamma‐secretase inhibitor, on amyloid‐β concentrations in the brain and CSF of cynomolgus monkeys 2010 ·Alzheimer s & Dementia ·Elizabeth Brigham, (unknown), Ruth Motter, Wherly P. Hoffman, Erich Goldbach, Dora Kholodenko, (unknown), (unknown), Gary D. Probst, (unknown), (unknown), John‐Michael Sauer, Gene G. Kinney, Daniel Ness	4
15	Partial Reduction of BACE1 Has Dramatic Effects on Alzheimer Plaque and Synaptic Pathology in APP Transgenic Mice 2007 ·Journal of Biological Chemistry ·Lisa McConlogue, Manuel Buttini, John P. Anderson, Elizabeth Brigham, Karen Chen, Stephen B. Freedman, Dora Games, Kelly Johnson‐Wood, Michael Lee, (unknown), Weiqun Liu, Ruth Motter, Sukanto Sinha	231
16	Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro 2001 ·Glia ·Lih‐Fen Lue, Russell E. Rydel, Elizabeth Brigham, (unknown), Harald Hampel, Greer M. Murphy, Libuse Brachova, (unknown), Douglas G. Walker, Yong Shen, Joseph Rogers	310
17	Oncostatin M and the Interleukin-6 and Soluble Interleukin-6 Receptor Complex Regulate α1-Antichymotrypsin Expression in Human Cortical Astrocytes 1998 ·Journal of Biological Chemistry ·Tomasz Kordula, Russell E. Rydel, Elizabeth Brigham, Friedemann Horn, Peter C. Heinrich, James Travis	101
18	Aggregated Amyloid-β Protein Induces Cortical Neuronal Apoptosis and Concomitant “Apoptotic” Pattern of Gene Induction 1997 ·Journal of Neuroscience ·Steven Estus, H. Michael Tucker, (unknown), Sarah Wright, Elizabeth Brigham, Mark Wogulis, Russell E. Rydel	243
19	Secondary structure of amyloid beta peptide correlates with neurotoxic activity in vitro. 1994 ·Molecular Pharmacology ·Linda K. Simmons, Patrick C. May, K J Tomaselli, R E Rydel, Kimberly S. Fuson, Elizabeth Brigham, Sarah Wright, Ivan Lieberburg, Gerald W. Becker, David N. Brems	325
20	Postirradiation release of adenosine triphosphate from Escherichia coliBr 1953 ·Archives of Biochemistry and Biophysics ·Daniel Billen, Bernard L. Strehler, G. E. Stapleton, Elizabeth Brigham	27

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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