Elias S.J. Arnér

23.3k citations

198 papers · 17.0k indexed · 4 hit papers · h-index 62

Biochemistry top 0.05%
- Sulfur Compounds in Biology 22
Nutrition and Dietetics top 0.05%
- Selenium in Biological Systems 75
- Trace Elements in Health 21
Toxicology top 0.1%
Molecular Biology top 0.2%
- Redox biology and oxidative stress 128
- Glutathione Transferases and Polymorphisms 64
- Genomics, phytochemicals, and oxidative stress 23
- Biochemical and Molecular Research 11
Aging top 1%
Genetics
- Chronic Lymphocytic Leukemia Research 8

Co-authors: Arne Holmgren Jonas Nordberg Liangwei Zhong Qing Cheng Staffan Eriksson Edward E. Schmidt Linda Johansson Anna-Klara Rundlöf
Cited by: Biochemistry Nutrition and Dietetics Toxicology
Partner nations: Sweden United States Hungary

In The Last Decade

Elias S.J. Arnér

190 papers receiving 16.6k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2023 The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1
2009 Focus on mammalian thioredoxin reductases — Important selenoproteins with versatile functions
2001 Reactive oxygen species, antioxidants, and the mammalian thioredoxin system1 1This review is based on the licentiate thesis “Thioredoxin reductase—interactions with the redox active compounds 1-chloro-2,4-dinitrobenzene and lipoic acid” by Jonas Nordberg, 2001, Karolinska Institute, Stockholm, ISBN 91-631-1064-4.
2000 Physiological functions of thioredoxin and thioredoxin reductase

Peers

Countries citing papers authored by Elias S.J. Arnér

Since Specialization

Citations

This map shows the geographic impact of Elias S.J. Arnér's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Elias S.J. Arnér with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Elias S.J. Arnér more than expected).

Fields of papers citing papers by Elias S.J. Arnér

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Elias S.J. Arnér. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Elias S.J. Arnér. The network helps show where Elias S.J. Arnér may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Elias S.J. Arnér, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Elias S.J. Arnér Line = papers co-authored together Elias S.J. Arnér links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Bicyclic Selenenyl Sulfides with Tuned Bioreductive Step Rates Reveal Constraints for Probes Targeting Thioredoxin Reductase Lukas Zeisel,Lucas Dessen-Weissenhorn,Karoline Scholzen,Andrea Madabeni,Laura Orian,Elias S.J. Arnér,Oliver Thorn‐Seshold	2025	0
2	Bicyclic Selenenyl Sulfides with Tuned Bioreductive Step Rates Reveal Constraints for Probes Targeting Thioredoxin Reductase Lukas Zeisel,Lucas Dessen-Weissenhorn,Karoline Scholzen,Andrea Madabeni,Laura Orian,Elias S.J. Arnér,Oliver Thorn‐Seshold	2025	0
3	Anti-Tumoral Treatment with Thioredoxin Reductase 1 Inhibitor Auranofin Fosters Regulatory T Cell and B16F10 Expansion in Mice Michael Y. Bonner,Tamás Vancsik,Ana Coelho,Pierre Sabatier,Christian M. Beusch,Kejsi Zeqiraj,Carolin Svensson,Roman A. Zubarev,Elias S.J. Arnér,Rikard Holmdahl	2025	0
4	The inhibition of TXNRD1 by methylglyoxal impairs the intracellular control of Mycobacterium tuberculosis Hanxiong Li,Ruining Liu,Gokul Raj Kathamuthu,Radosveta Gencheva,Zhen Gong,Anna-Lena Scholz,Mohammad Alzrigat,Lucia Coppo,Elias S.J. Arnér,Martı́n E. Rottenberg	2025	0
5	Patient-derived TXNIP-deficient primary cells exhibit NRF2 activation linked to upregulation of glyoxalase 1 (GLO1) Shayida Maimaiti,Markus Dagnell,Lucia Coppo,Elias S.J. Arnér	2025	0
6	Endogenous electrophiles and peroxymonocarbonate can link tyrosine phosphorylation cascades with the cytosolic TXNRD1 selenoprotein and the KEAP1/NRF2 system Markus Dagnell,Elias S.J. Arnér	2024	4
7	Piperazine-Fused Cyclic Disulfides Unlock High-Performance Bioreductive Probes of Thioredoxins and Bifunctional Reagents for Thiol Redox Biology Lukas Zeisel,Jan G. Felber,Karoline Scholzen,Carina Schmitt,Alexander J. Wiegand,Leonid Komissarov,Elias S.J. Arnér,Oliver Thorn‐Seshold	2024	10
8	Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically Jan G. Felber,Lena Poczka,Karoline Scholzen,Lukas Zeisel,Martin S. Maier,Sander Busker,Ulrike Theisen,Christina Brandstädter,Katja Becker,Elias S.J. Arnér,Julia Thorn‐Seshold,Oliver Thorn‐Seshold	2022	28
9	Selective, Modular Probes for Thioredoxins Enabled by Rational Tuning of a Unique Disulfide Structure Motif Jan G. Felber,Lukas Zeisel,Lena Poczka,Karoline Scholzen,Sander Busker,Martin S. Maier,Ulrike Theisen,Christina Brandstädter,Katja Becker,Elias S.J. Arnér,Julia Thorn‐Seshold,Oliver Thorn‐Seshold	2021	34
10	Comment on “Evidence that the ProPerDP method is inadequate for protein persulfidation detection due to lack of specificity” Éva Dóka,Elias S.J. Arnér,Edward E. Schmidt,Tobias P. Dick,Albert van der Vliet,Jing Yang,Réka Szatmári,Tamás Ditrói,John L. Wallace,Giuseppe Cirino,Kenneth R. Olson,Hozumi Motohashi,Jon M. Fukuto,Michael D. Pluth,Martin Feelisch,Takaaki Akaike,David A. Wink,Louis J. Ignarro,Péter Nagy	2021	4
11	Characterization of Lead Compounds Targeting the Selenoprotein Thioredoxin Glutathione Reductase for Treatment of Schistosomiasis Haining Lyu,Pavel A. Petukhov,Paul R. Banta,Ajit Jadhav,Wendy Lea,Qing Cheng,Elias S.J. Arnér,Anton Simeonov,Gregory R. J. Thatcher,Francesco Angelucci,David L. Williams	2020	25
12	Control of protein function through oxidation and reduction of persulfidated states Éva Dóka,Tomoaki Ida,Markus Dagnell,Yumi Abiko,Nho Cong Luong,Noémi Balog,Tsuyoshi Takata,Belén Espinosa,Akira Nishimura,Qing Cheng,Yosuke Funato,Hiroaki Miki,Jon M. Fukuto,Justin R. Prigge,Edward E. Schmidt,Elias S.J. Arnér,Yoshito Kumagai,Takaaki Akaike,Péter Nagy	2020	153
13	Bicarbonate is essential for protein-tyrosine phosphatase 1B (PTP1B) oxidation and cellular signaling through EGF-triggered phosphorylation cascades Markus Dagnell,Qing Cheng,Syed Husain Mustafa Rizvi,Paul Pace,Benoît Boivin,Christine C. Winterbourn,Elias S.J. Arnér	2019	54
14	Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug Xiaonan Zhang,Karthik Selvaraju,Amir Ata Saei,Pádraig D’Arcy,Roman A. Zubarev,Elias S.J. Arnér,Stig Linder	2019	131
15	Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as “Doorstop” for NADPH Entry Ilaria Silvestri,Haining Lyu,Francesca Fata,Giovanna Boumis,A.E. Miele,Matteo Ardini,Rodolfo Ippoliti,Andrea Bellelli,Ajit Jadhav,Wendy Lea,Anton Simeonov,Qing Cheng,Elias S.J. Arnér,Gregory R. J. Thatcher,Pavel A. Petukhov,David L. Williams,Francesco Angelucci	2018	25
16	Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy William C. Stafford,Xiaoxiao Peng,Maria Hägg Olofsson,Xiaonan Zhang,Diane K. Luci,Frank Leigh Lu,Qing Cheng,L. Tresaugues,Thomas S. Dexheimer,Nathan P. Coussens,Martin Augsten,Hanna-Stina Martinsson Ahlzén,Owe Orwar,Arne Östman,Sharon Stone‐Elander,David J. Maloney,Ajit Jadhav,Anton Simeonov,Stig Linder,Elias S.J. Arnér	2018	164
17	Cross Talk in HEK293 Cells Between Nrf2, HIF, and NF-κB Activities upon Challenges with Redox Therapeutics Characterized with Single-Cell Resolution Katarina Johansson,Marcus Cebula,Olle Rengby,Kristian Dreij,Karl E. Carlström,Kristmundur Sigmundsson,Fredrik Piehl,Elias S.J. Arnér	2015	37
18	HER2-Positive Tumors Imaged Within 1 Hour Using a Site-Specifically ¹¹C-Labeled Sel-Tagged Affibody Molecule Helena Wållberg,Jonas Grafström,Qing Cheng,Frank Leigh Lu,Hanna-Stina Martinsson Ahlzén,Erik Samén,Jan-Olov Thorell,Katarina Johansson,Finn Dunås,Maria Hägg Olofsson,Sharon Stone‐Elander,Elias S.J. Arnér,Stefan Ståhl	2012	25
19	Mitochondrial peroxiredoxin 3 is rapidly oxidized in cells treated Kristin Brown,Sofi Eriksson,Elias S.J. Arnér,Mark B. Hampton	2008	1
20	Crystal Structure and Catalysis of the Selenoprotein Thioredoxin Reductase 1 Qing Cheng,Tatyana Sandalova,Ylva Lindqvist,Elias S.J. Arnér	2008	169

About Elias S.J. Arnér

Elias S.J. Arnér is a scholar working on Nutrition and Dietetics, Biochemistry and Molecular Biology, having authored 198 papers that have together received 17.0k indexed citations. Recurring topics across this work include Redox biology and oxidative stress (128 papers), Selenium in Biological Systems (75 papers), Glutathione Transferases and Polymorphisms (64 papers), Genomics, phytochemicals, and oxidative stress (23 papers), Sulfur Compounds in Biology (22 papers), Trace Elements in Health (21 papers), Biochemical and Molecular Research (11 papers) and Chronic Lymphocytic Leukemia Research (8 papers). The work is most often cited by research in Biochemistry (2.3k citations), Nutrition and Dietetics (4.0k citations) and Toxicology (743 citations). Elias S.J. Arnér has collaborated with scholars based in Sweden, United States and Hungary. Frequent co-authors include Arne Holmgren, Jonas Nordberg, Liangwei Zhong, Qing Cheng, Staffan Eriksson, Edward E. Schmidt, Linda Johansson, Anna-Klara Rundlöf, Marcus Cebula and Sofi Eriksson.

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