Arne Holmgren

56.4k total citations · 13 hit papers
386 papers, 45.9k citations indexed

About

Arne Holmgren is a scholar working on Molecular Biology, Biochemistry and Cell Biology. According to data from OpenAlex, Arne Holmgren has authored 386 papers receiving a total of 45.9k indexed citations (citations by other indexed papers that have themselves been cited), including 351 papers in Molecular Biology, 88 papers in Biochemistry and 60 papers in Cell Biology. Recurrent topics in Arne Holmgren's work include Redox biology and oxidative stress (324 papers), Glutathione Transferases and Polymorphisms (97 papers) and Sulfur Compounds in Biology (84 papers). Arne Holmgren is often cited by papers focused on Redox biology and oxidative stress (324 papers), Glutathione Transferases and Polymorphisms (97 papers) and Sulfur Compounds in Biology (84 papers). Arne Holmgren collaborates with scholars based in Sweden, United States and Germany. Arne Holmgren's co-authors include Jun Lu, Elias S.J. Arnér, Christopher Horst Lillig, Mikael Björnstedt, Carsten Berndt, Liangwei Zhong, Fredrik Åslund, Mikaela Luthman, Aristi P. Fernandes and Laura V. Papp and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Arne Holmgren

383 papers receiving 44.8k citations

Hit Papers

Physiological functions o... 1979 2026 1994 2010 2000 1985 2013 1989 2007 500 1000 1.5k 2.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Physiological functions of thioredoxin and thioredoxin reductase
    2000 2.0k citations Arne Holmgren et al. profile →
  2. THIOREDOXIN
    1985 1.7k citations Arne Holmgren profile →
  3. The thioredoxin antioxidant system
    2013 1.6k citations Jun Lu, Arne Holmgren Free Radical Biology and Medicine profile →
  4. Thioredoxin and Glutaredoxin Systems
    1989 1.5k citations Arne Holmgren Journal of Biological Chemistry profile →
  5. From Selenium to Selenoproteins: Synthesis, Identity, and Their Role in Human Health
    2007 1.0k citations Laura V. Papp, Jun Lu et al. Antioxidants and Redox Signaling profile →
  6. [21] Thioredoxin and thioredoxin reductase
    1995 821 citations Arne Holmgren et al. Methods in enzymology on CD-ROM/Methods in enzymology profile →
  7. Thioredoxin catalyzes the reduction of insulin disulfides by dithiothreitol and dihydrolipoamide.
    1979 818 citations Arne Holmgren Journal of Biological Chemistry profile →
  8. Unraveling the Biological Roles of Reactive Oxygen Species
    2011 633 citations Michael P. Murphy, Arne Holmgren et al. Cell Metabolism profile →
  9. Thioredoxin and Related Molecules–From Biology to Health and Disease
    2006 586 citations Christopher Horst Lillig, Arne Holmgren Antioxidants and Redox Signaling profile →
  10. The Role of the Thioredoxin and Glutaredoxin Pathways in Reducing Protein Disulfide Bonds in the Escherichia coliCytoplasm
    1997 529 citations Fredrik Åslund, Arne Holmgren et al. Journal of Biological Chemistry profile →
  11. Glutaredoxins: Glutathione-Dependent Redox Enzymes with Functions Far Beyond a Simple Thioredoxin Backup System
    2004 520 citations Arne Holmgren et al. Antioxidants and Redox Signaling profile →
  12. Rat liver thioredoxin and thioredoxin reductase: purification and characterization
    1982 519 citations Arne Holmgren et al. Biochemistry profile →
  13. Selenoproteins
    2008 503 citations Jun Lu, Arne Holmgren Journal of Biological Chemistry profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
Arne Holmgren 34.3k 8.2k 7.1k 5.3k 3.5k 386 45.9k
Earl R. Stadtman 26.4k 0.8× 4.9k 0.6× 5.8k 0.8× 5.5k 1.0× 3.6k 1.1× 284 48.9k
Christine C. Winterbourn 13.4k 0.4× 3.5k 0.4× 3.6k 0.5× 2.2k 0.4× 2.1k 0.6× 309 33.4k
Bert L. Vallée 16.6k 0.5× 11.6k 1.4× 1.7k 0.2× 3.3k 0.6× 2.9k 0.8× 489 38.4k
Ronald P. Mason 12.4k 0.4× 2.5k 0.3× 3.0k 0.4× 2.0k 0.4× 2.5k 0.7× 659 33.3k
Sten Orrenius 28.6k 0.8× 4.7k 0.6× 4.2k 0.6× 4.3k 0.8× 1.1k 0.3× 455 51.5k
Sue Goo Rhee 31.0k 0.9× 3.0k 0.4× 4.0k 0.6× 5.3k 1.0× 1.4k 0.4× 244 41.4k
Rafael Radí 14.9k 0.4× 2.3k 0.3× 6.8k 1.0× 2.4k 0.4× 1.8k 0.5× 339 36.9k
Michael P. Murphy 33.6k 1.0× 2.8k 0.3× 4.2k 0.6× 2.4k 0.5× 1.9k 0.6× 535 56.2k
Jay L. Zweíer 15.3k 0.4× 1.9k 0.2× 3.5k 0.5× 2.6k 0.5× 4.1k 1.2× 554 42.5k
Rodney L. Levine 13.2k 0.4× 3.0k 0.4× 2.1k 0.3× 3.0k 0.6× 1.1k 0.3× 204 27.1k

Countries citing papers authored by Arne Holmgren

Since Specialization
Citations

This map shows the geographic impact of Arne Holmgren's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Arne Holmgren with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Arne Holmgren more than expected).

Fields of papers citing papers by Arne Holmgren

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Arne Holmgren. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Arne Holmgren. The network helps show where Arne Holmgren may publish in the future.

Co-authorship network of co-authors of Arne Holmgren

This figure shows the co-authorship network connecting the top 25 collaborators of Arne Holmgren. A scholar is included among the top collaborators of Arne Holmgren based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Arne Holmgren. Arne Holmgren is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Lu, Jun, Vladimir J.N. Bykov, Xiaoyuan Ren, et al.. (2018). Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246. Scientific Reports. 8(1). 12671–12671. 55 indexed citations
2.
Ren, Xiaoyuan, Lili Zou, Xu Zhang, et al.. (2017). Redox Signaling Mediated by Thioredoxin and Glutathione Systems in the Central Nervous System. Antioxidants and Redox Signaling. 27(13). 989–1010. 258 indexed citations
3.
Rodríguez‐García, Aida, David Hevia, Juan C. Mayo, et al.. (2017). Thioredoxin 1 modulates apoptosis induced by bioactive compounds in prostate cancer cells. Redox Biology. 12. 634–647. 43 indexed citations
4.
Zhang, Huihui, Yatao Du, Xu Zhang, Jun Lu, & Arne Holmgren. (2013). Glutaredoxin 2 Reduces Both Thioredoxin 2 and Thioredoxin 1 and Protects Cells from Apoptosis Induced by Auranofin and 4-Hydroxynonenal. Antioxidants and Redox Signaling. 21(5). 669–681. 64 indexed citations
5.
Murphy, Michael P., Arne Holmgren, Nils‐Göran Larsson, et al.. (2011). Unraveling the Biological Roles of Reactive Oxygen Species. Cell Metabolism. 13(4). 361–366. 633 indexed citations breakdown →
6.
Zhang, Xu, Yujuan Zheng, Levi Fried, et al.. (2011). Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes. Free Radical Biology and Medicine. 50(7). 811–820. 51 indexed citations
7.
Evens, Andrew M., Paul T. Schumacker, Irene Helenowski, et al.. (2008). Hypoxia inducible factor‐alpha activation in lymphoma and relationship to the thioredoxin family. British Journal of Haematology. 141(5). 676–680. 38 indexed citations
8.
Berndt, Carsten, Christopher Horst Lillig, & Arne Holmgren. (2008). Thioredoxins and glutaredoxins as facilitators of protein folding. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1783(4). 641–650. 228 indexed citations
9.
Papp, Laura V., Jun Lu, Frank Striebel, et al.. (2006). The Redox State of SECIS Binding Protein 2 Controls Its Localization and Selenocysteine Incorporation Function. Molecular and Cellular Biology. 26(13). 4895–4910. 78 indexed citations
10.
Tran, Quang Hon, et al.. (2004). Stimulation of Fe–S cluster insertion into apoFNR by Escherichia coli glutaredoxins 1, 2 and 3 in vitro. FEBS Letters. 565(1-3). 203–206. 17 indexed citations
11.
Vlamis‐Gardikas, Alexios & Arne Holmgren. (2002). Thioredoxin and Glutaredoxin Isoforms. Methods in enzymology on CD-ROM/Methods in enzymology. 347. 286–296. 109 indexed citations
12.
Sandalova, Tatyana, Liangwei Zhong, Ylva Lindqvist, Arne Holmgren, & G. Schneider. (2001). Three-dimensional structure of a mammalian thioredoxin reductase: Implications for mechanism and evolution of a selenocysteine-dependent enzyme. Proceedings of the National Academy of Sciences. 98(17). 9533–9538. 277 indexed citations
13.
Zhong, Liangwei & Arne Holmgren. (2000). Essential Role of Selenium in the Catalytic Activities of Mammalian Thioredoxin Reductase Revealed by Characterization of Recombinant Enzymes with Selenocysteine Mutations. Journal of Biological Chemistry. 275(24). 18121–18128. 335 indexed citations
14.
Lillig, Christopher Horst, Jens D. Schwenn, Fredrik Åslund, et al.. (1999). New Thioredoxins and Glutaredoxins as Electron Donors of 3′-Phosphoadenylylsulfate Reductase. Journal of Biological Chemistry. 274(12). 7695–7698. 123 indexed citations
15.
Holmgren, Arne & Fredrik Åslund. (1995). [29] Glutaredoxin. Methods in enzymology on CD-ROM/Methods in enzymology. 252. 283–292. 259 indexed citations
16.
Kumar, Sushil, et al.. (1995). [22] Selenite and selenodiglutathione: Reactions with thioredoxin systems. Methods in enzymology on CD-ROM/Methods in enzymology. 252. 209–219. 56 indexed citations
17.
18.
19.
Grippo, Joseph F., et al.. (1987). The heat-stable cytosolic factor that promotes glucocorticoid receptor binding to DNA is neither thioredoxin nor ribonuclease. Journal of Steroid Biochemistry. 28(5). 449–457. 10 indexed citations
20.
Holmgren, Arne. (1980). Pyridine Nucleotide — Disulfide Oxidoreductases. Proceedings of the Fourth International Symposium on Polarization Phenomena in Nuclear Reactions. 36. 149–180. 36 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Earl R. Stadtman Breakdown of academic impact, for papers by Christine C. Winterbourn Breakdown of academic impact, for papers by Bert L. Vallée Breakdown of academic impact, for papers by Ronald P. Mason Breakdown of academic impact, for papers by Sten Orrenius Breakdown of academic impact, for papers by Sue Goo Rhee Breakdown of academic impact, for papers by Rafael Radí Breakdown of academic impact, for papers by Michael P. Murphy Breakdown of academic impact, for papers by Jay L. Zweíer Breakdown of academic impact, for papers by Rodney L. Levine
Rankless by CCL
2026