Louis J. Ignarro

36.2k total citations · 19 hit papers
281 papers, 29.5k citations indexed

About

Louis J. Ignarro is a scholar working on Physiology, Molecular Biology and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Louis J. Ignarro has authored 281 papers receiving a total of 29.5k indexed citations (citations by other indexed papers that have themselves been cited), including 150 papers in Physiology, 77 papers in Molecular Biology and 61 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Louis J. Ignarro's work include Nitric Oxide and Endothelin Effects (138 papers), Eicosanoids and Hypertension Pharmacology (35 papers) and Renin-Angiotensin System Studies (22 papers). Louis J. Ignarro is often cited by papers focused on Nitric Oxide and Endothelin Effects (138 papers), Eicosanoids and Hypertension Pharmacology (35 papers) and Renin-Angiotensin System Studies (22 papers). Louis J. Ignarro collaborates with scholars based in United States, Italy and Japan. Louis J. Ignarro's co-authors include Claudio Napoli, Georgette M. Buga, Jon M. Fukuto, K S Wood, R E Byrns, Norma Rogers, Margaret A. Bush, Jacob Rajfer, Michael P. Sherman and Carl A. Gruetter and has published in prestigious journals such as Science, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Louis J. Ignarro

281 papers receiving 28.4k citations

Hit Papers

Nitric oxide : biology and pathobiology 1980 2026 1995 2010 2000 1990 1987 1989 1992 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Nitric oxide : biology and pathobiology
    2000 1.1k citations Louis J. Ignarro Academic Press eBooks profile →
  2. Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide
    1990 1.1k citations Louis J. Ignarro profile →
  3. Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.
    1987 930 citations Louis J. Ignarro, R E Byrns et al. profile →
  4. Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein.
    1989 808 citations Louis J. Ignarro profile →
  5. Nitric Oxide as a Mediator of Relaxation of the Corpus Cavernosum in Response to Nonadrenergic, Noncholinergic Neurotransmission
    1992 799 citations Louis J. Ignarro et al. profile →
  6. Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine.
    1993 724 citations Louis J. Ignarro, Jon M. Fukuto et al. Proceedings of the National Academy of Sciences profile →
  7. Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle
    1990 691 citations Louis J. Ignarro, Georgette M. Buga et al. Biochemical and Biophysical Research Communications profile →
  8. Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide.
    1993 667 citations Louis J. Ignarro et al. The Journal of Immunology profile →
  9. Nitric Oxide as a Signaling Molecule in the Vascular System: An Overview
    1999 617 citations Louis J. Ignarro, Giuseppe Cirino et al. profile →
  10. Endothelium‐derived nitric oxide: actions and properties
    1989 548 citations Louis J. Ignarro profile →
  11. Relationship between cyclic guanosine 3':5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin.
    1981 464 citations Louis J. Ignarro et al. Journal of Pharmacology and Experimental Therapeutics profile →
  12. Signal transduction mechanisms involving nitric oxide
    1991 434 citations Louis J. Ignarro profile →
  13. Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis.
    1992 409 citations Toshio Hayashi, Jon M. Fukuto et al. Proceedings of the National Academy of Sciences profile →
  14. Shear stress-induced release of nitric oxide from endothelial cells grown on beads.
    1991 398 citations Georgette M. Buga, Jon M. Fukuto et al. profile →
  15. Nitric oxide. A novel signal transduction mechanism for transcellular communication.
    1990 396 citations Louis J. Ignarro profile →
  16. Negative feedback regulation of endothelial cell function by nitric oxide.
    1993 303 citations Georgette M. Buga, Louis J. Ignarro et al. profile →
  17. Methylene blue inhibits coronary arterial relaxation and guanylate cyclase activation by nitroglycerin, sodium nitrite, and amyl nitrite
    1981 279 citations Louis J. Ignarro et al. profile →
  18. Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury
    1992 271 citations Helen Young, Louis J. Ignarro et al. profile →
  19. Requirement of thiols for activation of coronary arterial guanylate cyclase by glyceryl trinitrate and sodium nitrite possible involvement of S-nitrosothiols
    1980 261 citations Louis J. Ignarro et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Louis J. Ignarro United States 89 13.7k 7.4k 5.1k 4.5k 3.0k 281 29.5k
Ulrich Förstermann Germany 87 16.4k 1.2× 8.8k 1.2× 7.1k 1.4× 4.7k 1.0× 3.3k 1.1× 263 32.4k
Harald Schmidt Germany 91 14.2k 1.0× 9.1k 1.2× 4.5k 0.9× 3.3k 0.7× 4.4k 1.5× 372 29.5k
Paul L. Huang United States 87 11.8k 0.9× 10.0k 1.4× 6.1k 1.2× 2.9k 0.6× 2.9k 1.0× 260 31.0k
Ferid Murad United States 88 14.9k 1.1× 11.3k 1.5× 6.8k 1.3× 3.7k 0.8× 2.1k 0.7× 338 29.1k
Paul M. Vanhoutte Hong Kong 89 15.8k 1.2× 7.5k 1.0× 9.1k 1.8× 6.3k 1.4× 1.9k 0.6× 432 29.7k
Rudi Busse Germany 101 18.2k 1.3× 10.3k 1.4× 9.8k 1.9× 7.7k 1.7× 4.1k 1.4× 316 35.8k
E.A. Higgs United Kingdom 21 10.6k 0.8× 4.1k 0.6× 3.7k 0.7× 3.1k 0.7× 1.6k 0.5× 28 19.2k
David A. Wink United States 101 14.2k 1.0× 10.1k 1.4× 2.4k 0.5× 6.6k 1.5× 4.4k 1.5× 355 35.8k
Ingrid Fleming Germany 86 10.6k 0.8× 9.4k 1.3× 6.2k 1.2× 7.7k 1.7× 2.4k 0.8× 346 27.7k
Bernd Mayer Austria 82 12.4k 0.9× 7.3k 1.0× 3.6k 0.7× 3.6k 0.8× 1.6k 0.5× 514 24.0k

Countries citing papers authored by Louis J. Ignarro

Since Specialization
Citations

This map shows the geographic impact of Louis J. Ignarro's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Louis J. Ignarro with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Louis J. Ignarro more than expected).

Fields of papers citing papers by Louis J. Ignarro

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Louis J. Ignarro. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Louis J. Ignarro. The network helps show where Louis J. Ignarro may publish in the future.

Co-authorship network of co-authors of Louis J. Ignarro

This figure shows the co-authorship network connecting the top 25 collaborators of Louis J. Ignarro. A scholar is included among the top collaborators of Louis J. Ignarro based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Louis J. Ignarro. Louis J. Ignarro is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Karlsson, J., Per Jynge, & Louis J. Ignarro. (2023). Exacerbated Neuropathy in POLAR A and M Trials Due to Redox Interaction of PledOx-Associated Mn2+ and Oxaliplatin-Associated Pt2+. Antioxidants. 12(3). 608–608. 4 indexed citations
2.
Dóka, Éva, Elias S.J. Arnér, Edward E. Schmidt, et al.. (2021). Comment on “Evidence that the ProPerDP method is inadequate for protein persulfidation detection due to lack of specificity”. Science Advances. 7(17). 4 indexed citations
3.
Meldrum, David R., et al.. (2011). The Link Between Erectile and Cardiovascular Health: The Canary in the Coal Mine. The American Journal of Cardiology. 108(4). 599–606. 61 indexed citations
4.
Kwon, Kyoung Ja, Kyu Suk Cho, Sung Hoon Lee, et al.. (2011). Regulation of tissue plasminogen activator/plasminogen activator inhibitor‐1 by hydrocortisone in rat primary astrocytes. Journal of Neuroscience Research. 89(7). 1059–1069. 8 indexed citations
5.
Nigris, Filomena de, Raffaele Rossiello, Concetta Schiano, et al.. (2008). Deletion of Yin Yang 1 Protein in Osteosarcoma Cells on Cell Invasion and CXCR4/Angiogenesis and Metastasis. Cancer Research. 68(6). 1797–1808. 68 indexed citations
6.
Crimi, Ettore, Louis J. Ignarro, & Claudio Napoli. (2007). Microcirculation and oxidative stress. Free Radical Research. 41(12). 1364–1375. 95 indexed citations
7.
Pryor, William A., K. N. Houk, Christopher S. Foote, et al.. (2006). Free radical biology and medicine: it's a gas, man!. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 291(3). R491–R511. 356 indexed citations
8.
Azizzadeh, Babak, Georgette M. Buga, Gerald S. Berke, et al.. (2003). Inhibitors of Nitric Oxide Promote Microvascular Thrombosis. Archives of Facial Plastic Surgery. 5(1). 31–35. 11 indexed citations
9.
Juliet, Packiasamy A.R., Toshio Hayashi, Akihisa Iguchi, & Louis J. Ignarro. (2003). Concomitant production of nitric oxide and superoxide in human macrophages. Biochemical and Biophysical Research Communications. 310(2). 367–370. 30 indexed citations
10.
Napoli, Claudio, Lilach O. Lerman, Filomena de Nigris, Joseph Loscalzo, & Louis J. Ignarro. (2002). Glycoxidized low-density lipoprotein downregulates endothelial nitricoxide synthase in human coronary cells. Journal of the American College of Cardiology. 40(8). 1515–1522. 36 indexed citations
11.
Ignarro, Louis J., et al.. (2002). Nebivolol inhibits vascular smooth muscle cell proliferation by mechanisms involving nitric oxide but not cyclic GMP. Nitric Oxide. 7(2). 83–90. 30 indexed citations
12.
Ma, Li, Susan N. Elliott, Giuseppe Cirino, et al.. (2001). Platelets modulate gastric ulcer healing: Role of endostatin and vascular endothelial growth factor release. Proceedings of the National Academy of Sciences. 98(11). 6470–6475. 191 indexed citations
13.
Ignarro, Louis J.. (2000). Nitric oxide : biology and pathobiology. Academic Press eBooks. 1107 indexed citations breakdown →
14.
Mizuno, A, et al.. (1997). Endothelial stunning and myocyte recovery after reperfusion of jeopardized muscle: A role of l-arginine blood cardioplegia. Journal of Thoracic and Cardiovascular Surgery. 113(2). 379–389. 36 indexed citations
15.
Gelabert, Hugh A., et al.. (1997). Cigarette Smoking Increases Endothelial-Derived Vasorelaxation in the Rat Carotid Artery in a Dose-Dependent Manner. Journal of Surgical Research. 71(2). 101–106. 29 indexed citations
16.
Glasgow, Robert E., Georgette M. Buga, Louis J. Ignarro, Gautam Chaudhuri, & Michaël Heymann. (1997). Endothelium-derived relaxing factor as a mediator of bradykinin-induced perinatal pulmonary vasodilatation in fetal sheep. Reproduction Fertility and Development. 9(2). 213–216. 5 indexed citations
17.
Pearl, Jeffrey M., Hillel Laks, Davis C. Drinkwater, et al.. (1994). Loss of endothelium-dependent vasodilatation and nitric oxide release after myocardial protection with University of Wisconsin solution. Journal of Thoracic and Cardiovascular Surgery. 107(1). 257–264. 54 indexed citations
18.
Fukuto, Jon M., Adrian J. Hobbs, & Louis J. Ignarro. (1993). Conversion of Nitroxyl (HNO) to Nitric Oxide (NO) in Biological Systems: The Role of Physiological Oxidants and Relevance to the Biological Activity of HNO. Biochemical and Biophysical Research Communications. 196(2). 707–713. 130 indexed citations
19.
Ignarro, Louis J., R E Byrns, Georgette M. Buga, K S Wood, & Gautam Chaudhuri. (1988). Pharmacological evidence that endothelium-derived relaxing factor is nitric oxide: use of pyrogallol and superoxide dismutase to study endothelium-dependent and nitric oxide-elicited vascular smooth muscle relaxation.. Journal of Pharmacology and Experimental Therapeutics. 244(1). 181–189. 186 indexed citations
20.
Ignarro, Louis J.. (1974). Release of Neutral Protease and β-Glucuronidase from Human Neutrophils in the Presence of Cartilage Treated with Various Immunologic Reactants. The Journal of Immunology. 113(1). 298–308. 26 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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