Elaine Huston

3.3k citations

40 papers · 2.7k indexed · 1 hit paper · h-index 30

Molecular Biology top 5%
Pharmacology top 1%
Cellular and Molecular Neuroscience top 5%
Cardiology and Cardiovascular Medicine top 5%
Physiology top 10%

Co-authors: Miles D. Houslay George S. Baillie Grant Scotland Annette Dolphin Theresa McSorley Graeme B. Bolger Irene Gall Elaine V. Hill
Topics: Phosphodiesterase function and regulation (30 papers)Receptor Mechanisms and Signaling (24 papers)Cholinesterase and Neurodegenerative Diseases (16 papers)
Cited by: Pharmacology Molecular Biology Cellular and Molecular Neuroscience
Journals: Science Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United Kingdom United States Germany

In The Last Decade

Elaine Huston

40 papers receiving 2.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signaling

2005 507 citations J. Kirsty Millar, Ben Pickard et al. Science profile →

Peers

Countries citing papers authored by Elaine Huston

Since Specialization

Citations

This map shows the geographic impact of Elaine Huston's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Elaine Huston with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Elaine Huston more than expected).

Fields of papers citing papers by Elaine Huston

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Elaine Huston. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Elaine Huston. The network helps show where Elaine Huston may publish in the future.

Co-authorship network of co-authors of Elaine Huston

This figure shows the co-authorship network connecting the top 25 collaborators of Elaine Huston. A scholar is included among the top collaborators of Elaine Huston based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Elaine Huston. Elaine Huston is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Mitotic activation of the DISC1-inducible cyclic AMP phosphodiesterase-4D9 (PDE4D9), through multi-site phosphorylation, influences cell cycle progression 2014 ·Cellular Signalling ·(unknown),(unknown),Elaine V. Hill,David Henderson,(unknown),(unknown),(unknown),Lynne S. Cairns,Allan J. Dunlop,George S. Baillie,Elaine Huston,Miles D. Houslay	23
2	cAMP controls mTOR through regulation of the dynamic interaction between Rheb and Phosphodiesterase 4D 2010 ·Molecular and Cellular Biochemistry ·(unknown),(unknown),(unknown),Elaine Huston,Do‐Hyung Kim,(unknown),(unknown),(unknown),(unknown)	6
3	Cyclic AMP Phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a Vascular Endothelial Cadherin (VE-Cad)-based Signaling Complex and Controls cAMP-mediated Vascular Permeability 2010 ·Journal of Biological Chemistry ·(unknown),(unknown),Elaine Huston,(unknown),Lindsay S. Wilson,Stuart J. Netherton,Martin J. Lynch,George S. Baillie,Miles D. Houslay,Donald H. Maurice	80
4	MEK1 Binds Directly to βArrestin1, Influencing Both Its Phosphorylation by ERK and the Timing of Its Isoprenaline-stimulated Internalization 2009 ·Journal of Biological Chemistry ·Dong Meng,Martin J. Lynch,Elaine Huston,Michael Beyermann,Jenny Eichhorst,David R. Adams,Enno Klußmann,Miles D. Houslay,George S. Baillie	59
5	PDE4 Associates with Different Scaffolding Proteins: Modulating Interactions as Treatment for Certain Diseases 2008 ·Handbook of experimental pharmacology ·Angela McCahill,Elaine Huston,X. Li,Miles D. Houslay	33
6	DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signalingbreakdown → 2005 ·Science ·J. Kirsty Millar,Ben Pickard,Shaun Mackie,Rachel James,Sheila Christie,(unknown),M. P. Malloy,Jennifer E. Chubb,Elaine Huston,George S. Baillie,Pippa A. Thomson,Elaine V. Hill,Nicholas J. Brandon,Jean‐Christophe Rain,Luiz Miguel Camargo,Paul J. Whiting,Miles D. Houslay,Douglas Blackwood,Walter Muir,David J. Porteous	507
7	Identification and Characterization of PDE4A11, a Novel, Widely Expressed Long Isoform Encoded by the Human PDE4A cAMP Phosphodiesterase Gene 2005 ·Molecular Pharmacology ·(unknown),(unknown),Elaine Huston,(unknown),Thomas M. Houslay,York-Fong Cheung,(unknown),(unknown),Robin A.J. Smith,Irene Gall,Richard G. Knowles,Michael L. Sullivan,Miles D. Houslay	42
8	Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process 2003 ·Cellular Signalling ·(unknown),(unknown),(unknown),George S. Baillie,Elaine Huston,Irene Gall,David R. Adams,Miles D. Houslay	34
9	The Unique Amino-terminal Region of the PDE4D5 cAMP Phosphodiesterase Isoform Confers Preferential Interaction with β-Arrestins 2003 ·Journal of Biological Chemistry ·Graeme B. Bolger,Angela McCahill,Elaine Huston,York-Fong Cheung,Theresa McSorley,George S. Baillie,Miles D. Houslay	88
10	Attenuation of the Activity of the cAMP-specific Phosphodiesterase PDE4A5 by Interaction with the Immunophilin XAP2 2003 ·Journal of Biological Chemistry ·Graeme B. Bolger,Alexander Peden,Michael R. Steele,(unknown),David G. McEwan,(unknown),Elaine Huston,George S. Baillie,Miles D. Houslay	131
11	In addition to the SH3 binding region, multiple regions within the N-terminal noncatalytic portion of the cAMP-specific phosphodiesterase, PDE4A5, contribute to its intracellular targeting 2002 ·Cellular Signalling ·Matthew Beard,Elaine Huston,(unknown),Irene Gall,Ian McPhee,Stephen J. Yarwood,Grant Scotland,Miles D. Houslay	39
12	TAPAS-1, a Novel Microdomain within the Unique N-terminal Region of the PDE4A1 cAMP-specific Phosphodiesterase That Allows Rapid, Ca2+-triggered Membrane Association with Selectivity for Interaction with Phosphatidic Acid 2002 ·Journal of Biological Chemistry ·George S. Baillie,Elaine Huston,Grant Scotland,(unknown),Irene Gall,Alexander Peden,(unknown),Emma S. Houslay,A Currie,Trevor R. Pettitt,Adrian R. Walmsley,Michael J.O. Wakelam,Jim Warwicker,Miles D. Houslay	131
13	Molecular Cloning, Genomic Positioning, Promoter Identification, and Characterization of the Novel Cyclic AMP-Specific Phosphodiesterase PDE4A10 2001 ·Molecular Pharmacology ·Graham Rena,(unknown),Annette H. Ross,(unknown),Ian McPhee,(unknown),Elaine Huston,Michael L. Sullivan,Miles D. Houslay	57
14	Association with the SRC Family Tyrosyl Kinase LYN Triggers a Conformational Change in the Catalytic Region of Human cAMP-specific Phosphodiesterase HSPDE4A4B 1999 ·Journal of Biological Chemistry ·Ian McPhee,Stephen J. Yarwood,Grant Scotland,Elaine Huston,Matthew Beard,Annette H. Ross,Emma S. Houslay,Miles D. Houslay	101
15	Intracellular Compartmentalization of PDE4 Cyclic AMP-Specific Phosphodiesterases 1998 ·Methods ·Grant Scotland,Matthew Beard,Suat Erdoğan,Elaine Huston,(unknown),Simon J. MacKenzie,Alexander Peden,L Pooley,Graham Rena,A.H. Ross,Stephen J. Yarwood,Miles D. Houslay	10
16	Altered Expression of PDE1 and PDE4 Cyclic Nucleotide Phosphodiesterase Isoforms in 7-oxo-prostacyclin-preconditioned Rat Heart 1997 ·Journal of Molecular and Cellular Cardiology ·Milena Kostić,Suat Erdoğan,Graham Rena,Gudrun H. Borchert,(unknown),Sabine Bartel,Grant Scotland,Elaine Huston,Miles D. Houslay,Elmar Krause	69
17	The Human Cyclic AMP-specific Phosphodiesterase PDE-46 (HSPDE4A4B) Expressed in Transfected COS7 Cells Occurs as Both Particulate and Cytosolic Species That Exhibit Distinct Kinetics of Inhibition by the Antidepressant Rolipram 1996 ·Journal of Biological Chemistry ·Elaine Huston,L Pooley,(unknown),Grant Scotland,Ian McPhee,Michael L. Sullivan,Graeme B. Bolger,Miles D. Houslay	96
18	The involvement of multiple calcium channel sub-types in glutamate release from cerebellar granule cells and its modulation by GABAB receptor activation 1995 ·Neuroscience ·Elaine Huston,(unknown),(unknown),Annette Dolphin	55
19	Cycloheximide abolishes pertussis toxin-induced increase in glutamate release from cerebellar granule neurones 1994 ·Neuroscience Letters ·(unknown),Elaine Huston,Annette Dolphin	7
20	Pertussis toxin treatment increases glutamate release and dihydropyridine binding sites in cultured rat cerebellar granule neurons 1993 ·Neuroscience ·Elaine Huston,(unknown),Marva I. Sweeney,(unknown),M.S. Fazeli,Annette Dolphin	40

About Elaine Huston

Elaine Huston is a scholar working on Pharmacology, Molecular Biology and Cellular and Molecular Neuroscience, having authored 40 papers that have together received 2.7k indexed citations. Recurring topics across this work include Phosphodiesterase function and regulation (30 papers), Receptor Mechanisms and Signaling (24 papers) and Cholinesterase and Neurodegenerative Diseases (16 papers). The work is most often cited by research in Pharmacology (722 citations), Molecular Biology (2.3k citations) and Cellular and Molecular Neuroscience (506 citations). Elaine Huston has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Miles D. Houslay, George S. Baillie, Grant Scotland, Annette Dolphin, Theresa McSorley, Graeme B. Bolger, Irene Gall, Elaine V. Hill, Ian McPhee and Martin J. Lynch. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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