Elaine Huston

3.3k citations

40 papers · 2.7k indexed · 1 hit paper · h-index 30

Pharmacology top 1%
- Cholinesterase and Neurodegenerative Diseases 16
Molecular Biology top 5%
- Phosphodiesterase function and regulation 30
- Receptor Mechanisms and Signaling 24
- Ion channel regulation and function 5
- Protein Kinase Regulation and GTPase Signaling 3
Cellular and Molecular Neuroscience top 5%
- Neuroscience and Neuropharmacology Research 4
Cardiology and Cardiovascular Medicine top 5%
- Renin-Angiotensin System Studies 5
Aging top 10%
Physiology
- Nitric Oxide and Endothelin Effects 2

Co-authors: Miles D. Houslay George S. Baillie Grant Scotland Annette Dolphin Theresa McSorley Graeme B. Bolger Irene Gall Elaine V. Hill
Cited by: Pharmacology Molecular Biology Cellular and Molecular Neuroscience
Journals: Science (1 paper)Proceedings of the National Academy of Sciences (2 papers)Journal of Biological Chemistry (9 papers)
Partner nations: United Kingdom United States Germany

In The Last Decade

Elaine Huston

40 papers receiving 2.6k citations

Hit Papers

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Peers

Countries citing papers authored by Elaine Huston

Since Specialization

Citations

This map shows the geographic impact of Elaine Huston's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Elaine Huston with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Elaine Huston more than expected).

Fields of papers citing papers by Elaine Huston

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Elaine Huston. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Elaine Huston. The network helps show where Elaine Huston may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Elaine Huston, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Elaine Huston Line = papers co-authored together Elaine Huston links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Mitotic activation of the DISC1-inducible cyclic AMP phosphodiesterase-4D9 (PDE4D9), through multi-site phosphorylation, influences cell cycle progression Cellular Signalling ·Catherine L. Sheppard,Louisa C.Y. Lee,Elaine V. Hill,David Henderson,Diana F. Anthony,Daniel M. Houslay,Krishna C. Yalla,Lynne S. Cairns,Allan J. Dunlop,George S. Baillie,Elaine Huston,Miles D. Houslay	2014	23
2	cAMP controls mTOR through regulation of the dynamic interaction between Rheb and Phosphodiesterase 4D Molecular and Cellular Biochemistry ·HW Kim,SH Ha,MN Lee,Elaine Huston,Do‐Hyung Kim,Sangcheol Jang,PG Suh,Houslay,SH Ryu	2010	6
3	Cyclic AMP Phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a Vascular Endothelial Cadherin (VE-Cad)-based Signaling Complex and Controls cAMP-mediated Vascular Permeability Journal of Biological Chemistry ·Sarah Rampersad,Jeffrey D. Ovens,Elaine Huston,M. Bibiana Umana,Lindsay S. Wilson,Stuart J. Netherton,Martin J. Lynch,George S. Baillie,Miles D. Houslay,Donald H. Maurice	2010	80
4	MEK1 Binds Directly to βArrestin1, Influencing Both Its Phosphorylation by ERK and the Timing of Its Isoprenaline-stimulated Internalization Journal of Biological Chemistry ·Dong Meng,Martin J. Lynch,Elaine Huston,Michael Beyermann,Jenny Eichhorst,David R. Adams,Enno Klußmann,Miles D. Houslay,George S. Baillie	2009	59
5	PDE4 Associates with Different Scaffolding Proteins: Modulating Interactions as Treatment for Certain Diseases Handbook of experimental pharmacology ·Angela McCahill,Elaine Huston,X. Li,Miles D. Houslay	2008	33
6	DISC1 and PDE4B Are Interacting Genetic Factors in Schizophrenia That Regulate cAMP Signalingbreakdown → Science ·J. Kirsty Millar,Ben Pickard,Shaun Mackie,Rachel James,Sheila Christie,Sebastienne R. Buchanan,M. P. Malloy,Jennifer E. Chubb,Elaine Huston,George S. Baillie,Pippa A. Thomson,Elaine V. Hill,Nicholas J. Brandon,Jean‐Christophe Rain,Luiz Miguel Camargo,Paul J. Whiting,Miles D. Houslay,Douglas Blackwood,Walter Muir,David J. Porteous	2005	507
7	Identification and Characterization of PDE4A11, a Novel, Widely Expressed Long Isoform Encoded by the Human PDE4A cAMP Phosphodiesterase Gene Molecular Pharmacology ·Derek A. Wallace,Lee Ann Johnston,Elaine Huston,Douglas MacMaster,Thomas M. Houslay,York-Fong Cheung,Lachlan Campbell,Jenni E Millen,Robin A.J. Smith,Irene Gall,Richard G. Knowles,Michael L. Sullivan,Miles D. Houslay	2005	42
8	Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process Cellular Signalling ·Robert Terry,York-Fong Cheung,Morten Præstegaard,George S. Baillie,Elaine Huston,Irene Gall,David R. Adams,Miles D. Houslay	2003	34
9	The Unique Amino-terminal Region of the PDE4D5 cAMP Phosphodiesterase Isoform Confers Preferential Interaction with β-Arrestins Journal of Biological Chemistry ·Graeme B. Bolger,Angela McCahill,Elaine Huston,York-Fong Cheung,Theresa McSorley,George S. Baillie,Miles D. Houslay	2003	88
10	Attenuation of the Activity of the cAMP-specific Phosphodiesterase PDE4A5 by Interaction with the Immunophilin XAP2 Journal of Biological Chemistry ·Graeme B. Bolger,Alexander Peden,Michael R. Steele,Carolynn MacKenzie,David G. McEwan,Derek A. Wallace,Elaine Huston,George S. Baillie,Miles D. Houslay	2003	131
11	In addition to the SH3 binding region, multiple regions within the N-terminal noncatalytic portion of the cAMP-specific phosphodiesterase, PDE4A5, contribute to its intracellular targeting Cellular Signalling ·Matthew Beard,Elaine Huston,Lachlan Campbell,Irene Gall,Ian McPhee,Stephen J. Yarwood,Grant Scotland,Miles D. Houslay	2002	39
12	TAPAS-1, a Novel Microdomain within the Unique N-terminal Region of the PDE4A1 cAMP-specific Phosphodiesterase That Allows Rapid, Ca2+-triggered Membrane Association with Selectivity for Interaction with Phosphatidic Acid Journal of Biological Chemistry ·George S. Baillie,Elaine Huston,Grant Scotland,Matt Hodgkin,Irene Gall,Alexander Peden,Carolynn MacKenzie,Emma S. Houslay,A Currie,Trevor R. Pettitt,Adrian R. Walmsley,Michael J.O. Wakelam,Jim Warwicker,Miles D. Houslay	2002	131
13	Molecular Cloning, Genomic Positioning, Promoter Identification, and Characterization of the Novel Cyclic AMP-Specific Phosphodiesterase PDE4A10 Molecular Pharmacology ·Graham Rena,Fiona Begg,Annette H. Ross,Carolynn MacKenzie,Ian McPhee,Lachlan Campbell,Elaine Huston,Michael L. Sullivan,Miles D. Houslay	2001	57
14	Association with the SRC Family Tyrosyl Kinase LYN Triggers a Conformational Change in the Catalytic Region of Human cAMP-specific Phosphodiesterase HSPDE4A4B Journal of Biological Chemistry ·Ian McPhee,Stephen J. Yarwood,Grant Scotland,Elaine Huston,Matthew Beard,Annette H. Ross,Emma S. Houslay,Miles D. Houslay	1999	101
15	Intracellular Compartmentalization of PDE4 Cyclic AMP-Specific Phosphodiesterases Methods ·Grant Scotland,Matthew Beard,Suat Erdoğan,Elaine Huston,Fraser McCallum,Simon J. MacKenzie,Alexander Peden,L Pooley,Graham Rena,A.H. Ross,Stephen J. Yarwood,Miles D. Houslay	1998	10
16	Altered Expression of PDE1 and PDE4 Cyclic Nucleotide Phosphodiesterase Isoforms in 7-oxo-prostacyclin-preconditioned Rat Heart Journal of Molecular and Cellular Cardiology ·Milena Kostić,Suat Erdoğan,Graham Rena,Gudrun H. Borchert,B. Hoch,Sabine Bartel,Grant Scotland,Elaine Huston,Miles D. Houslay,Elmar Krause	1997	69
17	The Human Cyclic AMP-specific Phosphodiesterase PDE-46 (HSPDE4A4B) Expressed in Transfected COS7 Cells Occurs as Both Particulate and Cytosolic Species That Exhibit Distinct Kinetics of Inhibition by the Antidepressant Rolipram Journal of Biological Chemistry ·Elaine Huston,L Pooley,Pascale Julien,Grant Scotland,Ian McPhee,Michael L. Sullivan,Graeme B. Bolger,Miles D. Houslay	1996	96
18	The involvement of multiple calcium channel sub-types in glutamate release from cerebellar granule cells and its modulation by GABAB receptor activation Neuroscience ·Elaine Huston,G. Cullen,J. Russell Burley,Annette Dolphin	1995	55
19	Cycloheximide abolishes pertussis toxin-induced increase in glutamate release from cerebellar granule neurones Neuroscience Letters ·G. Cullen,Elaine Huston,Annette Dolphin	1994	7
20	Pertussis toxin treatment increases glutamate release and dihydropyridine binding sites in cultured rat cerebellar granule neurons Neuroscience ·Elaine Huston,G. Cullen,Marva I. Sweeney,Hayley Pearson,M.S. Fazeli,Annette Dolphin	1993	40

About Elaine Huston

Elaine Huston is a scholar working on Pharmacology, Molecular Biology and Cellular and Molecular Neuroscience, having authored 40 papers that have together received 2.7k indexed citations. Recurring topics across this work include Phosphodiesterase function and regulation (30 papers), Receptor Mechanisms and Signaling (24 papers), Cholinesterase and Neurodegenerative Diseases (16 papers), Ion channel regulation and function (5 papers), Renin-Angiotensin System Studies (5 papers), Neuroscience and Neuropharmacology Research (4 papers), Protein Kinase Regulation and GTPase Signaling (3 papers) and Nitric Oxide and Endothelin Effects (2 papers). The work is most often cited by research in Pharmacology (722 citations), Molecular Biology (2.3k citations) and Cellular and Molecular Neuroscience (506 citations). Elaine Huston has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Miles D. Houslay, George S. Baillie, Grant Scotland, Annette Dolphin, Theresa McSorley, Graeme B. Bolger, Irene Gall, Elaine V. Hill, Ian McPhee and Martin J. Lynch. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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