David R. Adams

6.4k citations

106 papers · 4.7k indexed · 1 hit paper · h-index 34

Molecular Biology top 2%
Organic Chemistry top 2%
Pharmacology top 1%
Cellular and Molecular Neuroscience top 2%
Physiology top 10%

Co-authors: Miles D. Houslay Patrick A. Kiely Dorit Ron Nigel J. Pyne Susan Pyne Surendra P. Bhatnagar George S. Baillie Tomáš Hudlický
Topics: Phosphodiesterase function and regulation (25 papers)Receptor Mechanisms and Signaling (21 papers)Cholinesterase and Neurodegenerative Diseases (15 papers)
Cited by: Pharmacology Molecular Biology Organic Chemistry
Journals: Chemical Reviews Journal of Biological Chemistry Nature Biotechnology
Partner nations: United Kingdom United States Germany

In The Last Decade

David R. Adams

100 papers receiving 4.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization

2003 614 citations Miles D. Houslay, David R. Adams profile →

Peers

Countries citing papers authored by David R. Adams

Since Specialization

Citations

This map shows the geographic impact of David R. Adams's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David R. Adams with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David R. Adams more than expected).

Fields of papers citing papers by David R. Adams

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David R. Adams. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David R. Adams. The network helps show where David R. Adams may publish in the future.

Co-authorship network of co-authors of David R. Adams

This figure shows the co-authorship network connecting the top 25 collaborators of David R. Adams. A scholar is included among the top collaborators of David R. Adams based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David R. Adams. David R. Adams is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Elliptic‐to‐parabolic Morrey spaces–potentials–capacities with applications to certain evolution PDE 2025 ·Journal of the London Mathematical Society ·David R. Adams,Jie Xiao	1
2	A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells 2021 ·Journal of Biological Chemistry ·(unknown),(unknown),(unknown),Rothwelle J. Tate,Federico Torta,Margaret Cunningham,David R. Adams,Susan Pyne,Nigel J. Pyne	3
3	Sphingosine Kinases as Druggable Targets 2018 ·Handbook of experimental pharmacology ·Susan Pyne,David R. Adams,Nigel J. Pyne	11
4	Sphingosine Kinase 2 in Autoimmune/Inflammatory Disease and the Development of Sphingosine Kinase 2 Inhibitors 2017 ·Trends in Pharmacological Sciences ·Nigel J. Pyne,David R. Adams,Susan Pyne	38
5	Sphingosine 1-phosphate and cancer 2017 ·Advances in Biological Regulation ·Nigel J. Pyne,(unknown),David R. Adams,Susan Pyne	93
6	Design and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist 2017 ·Bioorganic & Medicinal Chemistry ·Earl E. Clarke,Christopher I Jarvis,Maria B. Goncalves,S. Barret Kalindjian,David R. Adams,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Alan D. Borthwick,Jonathan Corcoran	9
7	Sphingosine Kinases: Emerging Structure–Function Insights 2016 ·Trends in Biochemical Sciences ·David R. Adams,Susan Pyne,Nigel J. Pyne	58
8	Phosphodiesterase inhibitors. Part 4: Design, synthesis and structure-activity relationships of dual PDE3/4-inhibitory fused bicyclic heteroaromatic-4,4-dimethylpyrazolones 2012 ·Bioorganic & Medicinal Chemistry Letters ·Koji Ochiai,(unknown),Akihiko Kojima,(unknown),N Ando,Kazuhiko Iwase,Tetsuya Kishi,(unknown),Yuichi Yageta,Tokutaro Yasue,David R. Adams,Yasushi Kohno	24
9	Reduced Inflammation and CD4 Loss in Acute SHIV Infection During Oral Pre-Exposure Prophylaxis 2012 ·The Journal of Infectious Diseases ·Ellen N. Kersh,Wei Luo,Qi Zheng,David R. Adams,Debra L. Hanson,Ae S. Youngpairoj,Mian-er Cong,(unknown),R. M. Hendry,J McNicholl,Walid Heneine,J. Gerardo Garcı́a-Lerma	13
10	Serine Phosphorylation of the Insulin-like Growth Factor I (IGF-1) Receptor C-terminal Tail Restrains Kinase Activity and Cell Growth 2012 ·Journal of Biological Chemistry ·(unknown),Deirdre A. Buckley,Patrick A. Kiely,David R. Adams,Rosemary O’Connor	22
11	Phosphodiesterase inhibitors. Part 2: Design, synthesis, and structure–activity relationships of dual PDE3/4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory and bronchodilatory activity 2011 ·Bioorganic & Medicinal Chemistry Letters ·Koji Ochiai,N Ando,Kazuhiko Iwase,Tetsuya Kishi,Kazunori Fukuchi,(unknown),(unknown),Tokutaro Yasue,David R. Adams,Yasushi Kohno	27
12	RACK1, A multifaceted scaffolding protein: Structure and function 2011 ·Cell Communication and Signaling ·David R. Adams,Dorit Ron,Patrick A. Kiely	364
13	Extracellular Loop 2 of the Free Fatty Acid Receptor 2 Mediates Allosterism of a Phenylacetamide Ago-Allosteric Modulator 2011 ·Molecular Pharmacology ·Nicola J. Smith,Richard J. Ward,Leigh A. Stoddart,Brian D. Hudson,Evi Kostenis,Trond Ulven,(unknown),Christian Tränkle,Irina G. Tikhonova,David R. Adams,Graeme Milligan	69
14	p62 (SQSTM1) and cyclic AMP phosphodiesterase-4A4 (PDE4A4) locate to a novel, reversible protein aggregate with links to autophagy and proteasome degradation pathways 2010 ·Cellular Signalling ·Christian Frank,(unknown),Suryakiran Vadrevu,(unknown),Jonathan P. Day,(unknown),David R. Adams,George S. Baillie,Miles D. Houslay	36
15	MEK1 Binds Directly to βArrestin1, Influencing Both Its Phosphorylation by ERK and the Timing of Its Isoprenaline-stimulated Internalization 2009 ·Journal of Biological Chemistry ·Dong Meng,Martin J. Lynch,Elaine Huston,Michael Beyermann,Jenny Eichhorst,David R. Adams,Enno Klußmann,Miles D. Houslay,George S. Baillie	59
16	Spa Contact Dermatitis 2008 ·Dermatitis ·(unknown),James G. Marks,Bryan Anderson,David R. Adams	9
17	Interaction of caspase‐3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1) 2003 ·European Journal of Biochemistry ·Mhairi J. Frame,Rothwelle J. Tate,David R. Adams,Keith M. Morgan,Miles D. Houslay,Peter Vandenabeele,Nigel J. Pyne	9
18	The Development of a Marine Natural Product-based Antifouling Paint 2003 ·Biofouling ·J. Grant Burgess,Kenneth G. Boyd,Evelyn Armstrong,Zhong‐Tao Jiang,Liming Yan,Matz Berggren,(unknown),(unknown),Åke Granmo,David R. Adams	184
19	Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process 2003 ·Cellular Signalling ·(unknown),(unknown),(unknown),George S. Baillie,Elaine Huston,Irene Gall,David R. Adams,Miles D. Houslay	34
20	JM47, a cyclic tetrapeptide HC-toxin analogue from a marine Fusarium species 2002 ·Phytochemistry ·Zhong‐Tao Jiang,(unknown),Kenneth G. Boyd,David R. Adams,Alan S. F. Boyd,J. Grant Burgess	22

About David R. Adams

David R. Adams is a scholar working on Organic Chemistry, Pharmacology and Molecular Biology, having authored 106 papers that have together received 4.7k indexed citations. Recurring topics across this work include Phosphodiesterase function and regulation (25 papers), Receptor Mechanisms and Signaling (21 papers) and Cholinesterase and Neurodegenerative Diseases (15 papers). The work is most often cited by research in Pharmacology (724 citations), Molecular Biology (2.9k citations) and Organic Chemistry (1.0k citations). David R. Adams has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Miles D. Houslay, Patrick A. Kiely, Dorit Ron, Nigel J. Pyne, Susan Pyne, Surendra P. Bhatnagar, George S. Baillie, Tomáš Hudlický, Kenneth G. Boyd and J. Grant Burgess. Their work appears in journals such as Chemical Reviews, Journal of Biological Chemistry and Nature Biotechnology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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