David R. Adams

6.4k total citations · 1 hit paper
106 papers, 4.7k citations indexed

About

David R. Adams is a scholar working on Molecular Biology, Organic Chemistry and Pharmacology. According to data from OpenAlex, David R. Adams has authored 106 papers receiving a total of 4.7k indexed citations (citations by other indexed papers that have themselves been cited), including 70 papers in Molecular Biology, 34 papers in Organic Chemistry and 18 papers in Pharmacology. Recurrent topics in David R. Adams's work include Phosphodiesterase function and regulation (25 papers), Receptor Mechanisms and Signaling (21 papers) and Cholinesterase and Neurodegenerative Diseases (15 papers). David R. Adams is often cited by papers focused on Phosphodiesterase function and regulation (25 papers), Receptor Mechanisms and Signaling (21 papers) and Cholinesterase and Neurodegenerative Diseases (15 papers). David R. Adams collaborates with scholars based in United Kingdom, United States and Germany. David R. Adams's co-authors include Miles D. Houslay, Patrick A. Kiely, Dorit Ron, Nigel J. Pyne, Susan Pyne, Surendra P. Bhatnagar, George S. Baillie, Tomáš Hudlický, Kenneth G. Boyd and J. Grant Burgess and has published in prestigious journals such as Chemical Reviews, Journal of Biological Chemistry and Nature Biotechnology.

In The Last Decade

David R. Adams

100 papers receiving 4.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization

2003 614 citations Miles D. Houslay, David R. Adams Biochemical Journal profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
David R. Adams United Kingdom	34	2.9k	1.0k	724	649	316	106	4.7k
Mayumi Yoshida Japan	33	2.1k 0.7×	645 0.6×	666 0.9×	215 0.3×	274 0.9×	134	4.8k
Michel Gallant Canada	20	3.5k 1.2×	618 0.6×	633 0.9×	472 0.7×	435 1.4×	38	5.5k
Junichi Tanaka Japan	42	2.2k 0.8×	1.4k 1.4×	975 1.3×	918 1.4×	268 0.8×	233	6.0k
Keisuke Kato Japan	30	1.5k 0.5×	1.4k 1.3×	243 0.3×	272 0.4×	263 0.8×	194	3.8k
Kenji Omori Japan	37	3.3k 1.1×	464 0.5×	1.1k 1.5×	366 0.6×	451 1.4×	93	4.2k
Gordon L. Bundy United States	24	1.2k 0.4×	615 0.6×	620 0.9×	369 0.6×	400 1.3×	66	2.9k
Camille G. Wermuth France	34	2.1k 0.7×	1.3k 1.2×	436 0.6×	1.2k 1.8×	218 0.7×	81	4.2k
Alfons Lawen Australia	30	2.6k 0.9×	305 0.3×	421 0.6×	315 0.5×	275 0.9×	81	4.3k
Kit I. Tong Japan	30	7.5k 2.5×	642 0.6×	301 0.4×	571 0.9×	544 1.7×	43	9.3k

Countries citing papers authored by David R. Adams

Since Specialization

Citations

This map shows the geographic impact of David R. Adams's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David R. Adams with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David R. Adams more than expected).

Fields of papers citing papers by David R. Adams

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David R. Adams. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David R. Adams. The network helps show where David R. Adams may publish in the future.

Co-authorship network of co-authors of David R. Adams

This figure shows the co-authorship network connecting the top 25 collaborators of David R. Adams. A scholar is included among the top collaborators of David R. Adams based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with David R. Adams. David R. Adams is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Adams, David R. & Jie Xiao. (2025). Elliptic‐to‐parabolic Morrey spaces–potentials–capacities with applications to certain evolution PDE. Journal of the London Mathematical Society. 111(4). 1 indexed citations

Pyne, Nigel J., David R. Adams, & Susan Pyne. (2017). Sphingosine Kinase 2 in Autoimmune/Inflammatory Disease and the Development of Sphingosine Kinase 2 Inhibitors. Trends in Pharmacological Sciences. 38(7). 581–591. 38 indexed citations

Pyne, Nigel J., et al.. (2017). Sphingosine 1-phosphate and cancer. Advances in Biological Regulation. 68. 97–106. 93 indexed citations

Bolger, Graeme B., Allan J. Dunlop, Dong Meng, et al.. (2014). Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains. Cellular Signalling. 27(4). 756–769. 29 indexed citations

Day, Jonathan P., Zhong‐Tao Jiang, Christian Frank, et al.. (2011). Elucidation of a Structural Basis for the Inhibitor-Driven, p62 (SQSTM1)-Dependent Intracellular Redistribution of cAMP Phosphodiesterase-4A4 (PDE4A4). Journal of Medicinal Chemistry. 54(9). 3331–3347. 33 indexed citations

Ochiai, Koji, N Ando, Kazuhiko Iwase, et al.. (2011). Phosphodiesterase inhibitors. Part 2: Design, synthesis, and structure–activity relationships of dual PDE3/4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory and bronchodilatory activity. Bioorganic & Medicinal Chemistry Letters. 21(18). 5451–5456. 27 indexed citations

Smith, Nicola J., Richard J. Ward, Leigh A. Stoddart, et al.. (2011). Extracellular Loop 2 of the Free Fatty Acid Receptor 2 Mediates Allosterism of a Phenylacetamide Ago-Allosteric Modulator. Molecular Pharmacology. 80(1). 163–173. 69 indexed citations

Frank, Christian, Suryakiran Vadrevu, Jonathan P. Day, et al.. (2010). p62 (SQSTM1) and cyclic AMP phosphodiesterase-4A4 (PDE4A4) locate to a novel, reversible protein aggregate with links to autophagy and proteasome degradation pathways. Cellular Signalling. 22(10). 1576–1596. 36 indexed citations

Li, Xiang, Suryakiran Vadrevu, Allan J. Dunlop, et al.. (2010). Selective SUMO modification of cAMP-specific phosphodiesterase-4D5 (PDE4D5) regulates the functional consequences of phosphorylation by PKA and ERK. Biochemical Journal. 428(1). 55–65. 37 indexed citations

10.

Kersh, Ellen N., Wei Luo, David R. Adams, et al.. (2009). Evaluation of the lymphocyte trafficking drug FTY720 in SHIVSF162P3-infected rhesus macaques. Journal of Antimicrobial Chemotherapy. 63(4). 758–762. 16 indexed citations

11.

Li, Xiang, Ruth MacLeod, Allan J. Dunlop, et al.. (2009). A scanning peptide array approach uncovers association sites within the JNK/βarrestin signalling complex. FEBS Letters. 583(20). 3310–3316. 21 indexed citations

12.

Marks, James G., et al.. (2008). Spa Contact Dermatitis. Dermatitis. 19(2). 100–101. 9 indexed citations

13.

Johnston, Karen, Zhong‐Tao Jiang, Ian D. Collier, et al.. (2007). Concise routes to pyrazolo[1,5-a]pyridin-3-yl pyridazin-3-ones. Organic & Biomolecular Chemistry. 6(1). 175–186. 27 indexed citations

14.

Rinner, Uwe, et al.. (2004). Synthesis and biological activity of some structural modifications of pancratistatin. Bioorganic & Medicinal Chemistry Letters. 14(11). 2911–2915. 72 indexed citations

15.

Frame, Mhairi J., Rothwelle J. Tate, David R. Adams, et al.. (2003). Interaction of caspase‐3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1). European Journal of Biochemistry. 270(5). 962–970. 9 indexed citations

16.

Baillie, George S., et al.. (2003). Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process. Cellular Signalling. 15(10). 955–971. 34 indexed citations

17.

Adams, David R., et al.. (1998). N-Phenyl-1-aza-2-cyano-1, 3-butadienes: An intramolecular hetero Diels-Alder strategy for the construction of 1, 4-benzodiazepines. Tetrahedron Letters. 39(24). 4283–4286. 6 indexed citations

18.

Adams, David R., et al.. (1993). N- versus O-Alkylation of 2,3'-anhydrothymidine: reaction of the obtained pyrimidinium salts with azide ion. The Journal of Organic Chemistry. 58(11). 3030–3037. 10 indexed citations

19.

Adams, David R., et al.. (1974). Structure and syntheses of a new ketone from the essential oil of cedrus species. Tetrahedron Letters. 15(44). 3903–3904. 6 indexed citations

20.

Adams, David R., et al.. (1974). Synthesis and structures of edulan I and II. Journal of the Chemical Society Chemical Communications. 469–469. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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