Simon J. MacKenzie

2.9k citations

36 papers · 2.3k indexed · h-index 23

Molecular Biology top 5%
Pharmacology top 2%
Critical Care and Intensive Care Medicine top 1%
Epidemiology top 10%
Physiology top 10%

Co-authors: Miles D. Houslay George S. Baillie Ian McPhee Stephen J. Yarwood Graeme B. Bolger Ralf Hoffmann Timothy Walsh F. N. MacKirdy
Topics: Phosphodiesterase function and regulation (17 papers)Cholinesterase and Neurodegenerative Diseases (14 papers)Sepsis Diagnosis and Treatment (7 papers)
Cited by: Critical Care and Intensive Care Medicine Pharmacology Radiological and Ultrasound Technology
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry The EMBO Journal
Partner nations: United Kingdom United States Norway

In The Last Decade

Simon J. MacKenzie

36 papers receiving 2.2k citations

Peers

Countries citing papers authored by Simon J. MacKenzie

Since Specialization

Citations

This map shows the geographic impact of Simon J. MacKenzie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Simon J. MacKenzie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Simon J. MacKenzie more than expected).

Fields of papers citing papers by Simon J. MacKenzie

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Simon J. MacKenzie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Simon J. MacKenzie. The network helps show where Simon J. MacKenzie may publish in the future.

Co-authorship network of co-authors of Simon J. MacKenzie

This figure shows the co-authorship network connecting the top 25 collaborators of Simon J. MacKenzie. A scholar is included among the top collaborators of Simon J. MacKenzie based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Simon J. MacKenzie. Simon J. MacKenzie is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The Diversity of Leucocyte IgA Receptors 2015 ·Contributions to nephrology ·Michael A. Kerr,Wilson W. Stewart,(unknown),Morag R. Greer,Simon J. MacKenzie,Mike Steele	1
2	A rehabilitation intervention to promote physical recovery following intensive care: a detailed description of construct development, rationale and content together with proposed taxonomy to capture processes in a randomised controlled trial 2014 ·Trials ·Pam Ramsay,Lisa Salisbury,Judith L. Merriweather,Guro Huby,Janice Rattray,Alastair Hull,Stephen J. Brett,Simon J. MacKenzie,Gordon Murray,John Forbes,Timothy Walsh	17
3	A Defence of the Thesis that "The opportunities of the general practitioner are essential for the investigation of disease and the progress of medicine" 2012 ·International Journal of Epidemiology ·Simon J. MacKenzie	3
4	A randomised controlled trial evaluating a rehabilitation complex intervention for patients following intensive care discharge: the RECOVER study 2012 ·BMJ Open ·Timothy Walsh,Lisa Salisbury,Julia Boyd,Pam Ramsay,Judith L. Merriweather,Guro Huby,John Forbes,Janice Rattray,David Griffith,Simon J. MacKenzie,Alastair Hull,Steff Lewis,Gordon Murray	23
5	C5a Mediates Peripheral Blood Neutrophil Dysfunction in Critically Ill Patients 2009 ·American Journal of Respiratory and Critical Care Medicine ·Andrew Conway Morris,Kallirroi Kefala,Thomas S. Wilkinson,Kevin Dhaliwal,Lesley Farrell,Timothy Walsh,Simon J. MacKenzie,(unknown),Donald J. Davidson,Chris Haslett,Adriano G. Rossi,Jean‐Michel Sallenave,A. John Simpson	88
6	Rhodanine derivatives as novel inhibitors of PDE4 2008 ·Bioorganic & Medicinal Chemistry Letters ·Mark W. Irvine,Graham L. Patrick,(unknown),(unknown),Simon J. MacKenzie	49
7	The inhibitory profile of Ibudilast against the human phosphodiesterase enzyme family 2006 ·European Journal of Pharmacology ·Lucien C.D. Gibson,(unknown),Ian McPhee,R.A.E. Clayton,(unknown),Alison MacKenzie,(unknown),Michiaki Nagasawa,Patricia A. Stevens,Simon J. MacKenzie	117
8	Cyclic nucleotide signalling: a molecular approach to drug discovery for Alzheimer's disease 2005 ·Biochemical Society Transactions ·(unknown),Ian McPhee,(unknown),(unknown),PA Stevens,Daniel Spinks,Ann Cooreman,Simon J. MacKenzie	63
9	The effect of selective phosphodiesterase inhibitors, alone and in combination, on a murine model of allergic asthma 2004 ·Respiratory Research ·R.A.E. Clayton,Colin A. J. Dick,Alison MacKenzie,Michiaki Nagasawa,(unknown),(unknown),Simon J. MacKenzie	28
10	Red cell transfusion practice following the transfusion requirements in critical care (TRICC) study: prospective observational cohort study in a large UK intensive care unit 2003 ·Vox Sanguinis ·(unknown),Fiona McArdle,D. B. L. McClelland,Simon J. MacKenzie,Todd Walsh	65
11	Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A‐mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1) 2002 ·British Journal of Pharmacology ·Simon J. MacKenzie,George S. Baillie,Ian McPhee,(unknown),(unknown),Theresa McSorley,(unknown),Matthew Beard,Gino Van Heeke,Miles D. Houslay	215
12	Phorbol 12-myristate 13-acetate Triggers the Protein Kinase A-Mediated Phosphorylation and Activation of the PDE4D5 cAMP Phosphodiesterase in Human Aortic Smooth Muscle Cells through a Route Involving Extracellular Signal Regulated Kinase (ERK) 2001 ·Molecular Pharmacology ·George S. Baillie,Simon J. MacKenzie,Miles D. Houslay	5
13	Phorbol 12-myristate 13-acetate Triggers the Protein Kinase A-Mediated Phosphorylation and Activation of the PDE4D5 cAMP Phosphodiesterase in Human Aortic Smooth Muscle Cells through a Route Involving Extracellular Signal Regulated Kinase (ERK) 2001 ·Molecular Pharmacology ·George S. Baillie,Simon J. MacKenzie,Miles D. Houslay	60
14	Sub‐family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP‐specific phosphodiesterases 2000 ·British Journal of Pharmacology ·George S. Baillie,Simon J. MacKenzie,Ian McPhee,Miles D. Houslay	139
15	Should the pre-sedation Glasgow Coma Scale value be used when calculating Acute Physiology and Chronic Health Evaluation scores for sedated patients? 2000 ·Critical Care Medicine ·(unknown),Simon J. MacKenzie,F. N. MacKirdy,(unknown)	66
16	ERK2 Mitogen-activated Protein Kinase Binding, Phosphorylation, and Regulation of the PDE4D cAMP-specific Phosphodiesterases 2000 ·Journal of Biological Chemistry ·Simon J. MacKenzie,George S. Baillie,Ian McPhee,Graeme B. Bolger,Miles D. Houslay	206
17	Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells 2000 ·Biochemical Journal ·Simon J. MacKenzie,Miles D. Houslay	118
18	The effect of N -acetylcysteine on oxygen transport and uptake in patients with fulminant hepatic failure 1998 ·Hepatology ·Timothy Walsh,(unknown),Barbara J. Philips,Simon J. MacKenzie,(unknown)	68
19	Intracellular Compartmentalization of PDE4 Cyclic AMP-Specific Phosphodiesterases 1998 ·Methods ·Grant Scotland,Matthew Beard,Suat Erdoğan,Elaine Huston,(unknown),Simon J. MacKenzie,Alexander Peden,L Pooley,Graham Rena,A.H. Ross,Stephen J. Yarwood,Miles D. Houslay	10
20	IgM monoclonal antibodies recognizing FcαR but not FcγRIII trigger a respiratory burst in neutrophils although both trigger an increase in intracellular calcium levels and degranulation 1995 ·Biochemical Journal ·Simon J. MacKenzie,Michael A. Kerr	21

About Simon J. MacKenzie

Simon J. MacKenzie is a scholar working on Critical Care and Intensive Care Medicine, Pharmacology and Geriatrics and Gerontology, having authored 36 papers that have together received 2.3k indexed citations. Recurring topics across this work include Phosphodiesterase function and regulation (17 papers), Cholinesterase and Neurodegenerative Diseases (14 papers) and Sepsis Diagnosis and Treatment (7 papers). The work is most often cited by research in Critical Care and Intensive Care Medicine (360 citations), Pharmacology (496 citations) and Radiological and Ultrasound Technology (120 citations). Simon J. MacKenzie has collaborated with scholars based in United Kingdom, United States and Norway. Frequent co-authors include Miles D. Houslay, George S. Baillie, Ian McPhee, Stephen J. Yarwood, Graeme B. Bolger, Ralf Hoffmann, Timothy Walsh, F. N. MacKirdy, Matthew Beard and Gino Van Heeke. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and The EMBO Journal.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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