Richard G. Knowles

19.3k total citations · 7 hit papers
96 papers, 15.9k citations indexed

About

Richard G. Knowles is a scholar working on Physiology, Biochemistry and Molecular Biology. According to data from OpenAlex, Richard G. Knowles has authored 96 papers receiving a total of 15.9k indexed citations (citations by other indexed papers that have themselves been cited), including 62 papers in Physiology, 33 papers in Biochemistry and 20 papers in Molecular Biology. Recurrent topics in Richard G. Knowles's work include Nitric Oxide and Endothelin Effects (50 papers), Eicosanoids and Hypertension Pharmacology (22 papers) and Asthma and respiratory diseases (11 papers). Richard G. Knowles is often cited by papers focused on Nitric Oxide and Endothelin Effects (50 papers), Eicosanoids and Hypertension Pharmacology (22 papers) and Asthma and respiratory diseases (11 papers). Richard G. Knowles collaborates with scholars based in United Kingdom, Finland and United States. Richard G. Knowles's co-authors include Salvador Moncada, W. Alderton, Chris E. Cooper, Mark Salter, Richard Palmer, Miriam Palacios‐Callender, Ignacio Lizasoaín, S. Moncada, I. G. Charles and Carl P. Weiner and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and American Journal of Respiratory and Critical Care Medicine.

In The Last Decade

Richard G. Knowles

95 papers receiving 15.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Nitric oxide synthases: structure, function and inhibition

2001 2.9k citations W. Alderton, Chris E. Cooper et al. Biochemical Journal profile →
Nitric oxide synthases in mammals

1994 2.3k citations Richard G. Knowles et al. Biochemical Journal profile →
Nitric oxide synthases: structure, function and inhibition

2001 2.2k citations W. Alderton, Chris E. Cooper et al. Biochemical Journal profile →
Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.

1989 1.3k citations Richard G. Knowles et al. profile →
Induction of calcium-dependent nitric oxide synthases by sex hormones.

1994 923 citations Richard G. Knowles et al. profile →
1400W Is a Slow, Tight Binding, and Highly Selective Inhibitor of Inducible Nitric-oxide Synthase in Vitro and in Vivo

1997 727 citations Edward P. Garvey, Jeffrey A. Oplinger et al. Journal of Biological Chemistry profile →
Widespread tissue distribution, species distribution and changes in activity of Ca²⁺‐dependent and Ca²⁺‐independent nitric oxide synthases

1991 562 citations Mark Salter, Richard G. Knowles et al. profile →

Peers

Countries citing papers authored by Richard G. Knowles

Since Specialization

Citations

This map shows the geographic impact of Richard G. Knowles's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Richard G. Knowles with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Richard G. Knowles more than expected).

Fields of papers citing papers by Richard G. Knowles

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Richard G. Knowles. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Richard G. Knowles. The network helps show where Richard G. Knowles may publish in the future.

Co-authorship network of co-authors of Richard G. Knowles

This figure shows the co-authorship network connecting the top 25 collaborators of Richard G. Knowles. A scholar is included among the top collaborators of Richard G. Knowles based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Richard G. Knowles. Richard G. Knowles is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Exhaled volatile organic compounds as markers for medication use in asthma 2019 ·European Respiratory Journal ·Paul Brinkman, Waqar Ahmed, Cristina Gómez, Hugo Knobel, Hans Weda, T.J. Vink, Tamara M. E. Nijsen, Craig E. Wheelock, Sven‐Erik Dahlén, Paolo Montuschi, Richard G. Knowles, Susanne J. H. Vijverberg, Anke H. Maitland‐van der Zee, Peter J. Sterk, Stephen J. Fowler	36
2	GSK256066, an Exceptionally High-Affinity and Selective Inhibitor of Phosphodiesterase 4 Suitable for Administration by Inhalation: In Vitro, Kinetic, and In Vivo Characterization 2011 ·Journal of Pharmacology and Experimental Therapeutics ·Cathy Tralau-Stewart, Richard A. Williamson, Anthony T. Nials, (unknown), John A. Dawson, Graham Hart, (unknown), Yemisi Solanke, Fiona S. Lucas, Joanne Wiseman, Peter Ward, Lisa E. Ranshaw, Richard G. Knowles	51
3	Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor 2011 ·Bioorganic & Medicinal Chemistry Letters ·Robert J. Young, W. Alderton, (unknown), Paul Beswick, David Brown, (unknown), (unknown), John Dawson, C. Hamlett, Simon T. Hodgson, (unknown), Richard G. Knowles, Linda Russell, (unknown), James M. Woolven	2
4	In Vivo Characterization of GSK256066, a High-Affinity Inhaled Phosphodiesterase 4 Inhibitor 2011 ·Journal of Pharmacology and Experimental Therapeutics ·Anthony T. Nials, Cathy Tralau-Stewart, (unknown), (unknown), Lisa E. Ranshaw, Richard G. Knowles	41
5	House dust mite induces direct airway inflammationin vivo: implications for future disease therapy? 2009 ·European Respiratory Journal ·J. De Alba, Kristof Raemdonck, (unknown), Michael P. Collins, Sing‐Wai Wong, Anthony T. Nials, Richard G. Knowles, Maria G. Belvisi, Mark A. Birrell	45
6	Selective Inducible Nitric Oxide Synthase Inhibition has no Effect on Allergen Challenge in Asthma 2007 ·American Journal of Respiratory and Critical Care Medicine ·Dave Singh, Duncan Richards, Richard G. Knowles, (unknown), Ashley Woodcock, (unknown), Brian O’Connor	120
7	The role of nitric oxide in osteoarthritis 2007 ·Scandinavian Journal of Rheumatology ·Katriina Vuolteenaho, Teemu Moilanen, Richard G. Knowles, Eeva Moilanen	95
8	y+ LAT-1 mediates transport of the potent and selective iNOS inhibitor, GW274150, in control J774 macrophages 2006 ·Amino Acids ·Anwar R. Baydoun, Joan Bertran, (unknown), John A. Dawson, Manuel Palacı́n, Richard G. Knowles	6
9	Identification and Characterization of PDE4A11, a Novel, Widely Expressed Long Isoform Encoded by the Human PDE4A cAMP Phosphodiesterase Gene 2005 ·Molecular Pharmacology ·(unknown), (unknown), Elaine Huston, (unknown), Thomas M. Houslay, York-Fong Cheung, (unknown), (unknown), Robin A.J. Smith, Irene Gall, Richard G. Knowles, Michael L. Sullivan, Miles D. Houslay	42
10	Assay of NOS Activity by the Measurement of Conversion of Oxyhemoglobin to Methemoglobin by NO 2003 ·Humana Press eBooks ·Mark Salter, Richard G. Knowles	37
11	Regulation of the nitric oxide production resulting from the glucocorticoid-insensitive expression of iNOS in human osteoarthritic cartilage 2001 ·Osteoarthritis and Cartilage ·Katriina Vuolteenaho, Teemu Moilanen, N al-Saffar, Richard G. Knowles, Eeva Moilanen	39
12	Nitric oxide synthases: structure, function and inhibition breakdown → 2001 ·Biochemical Journal ·W. Alderton, Chris E. Cooper, Richard G. Knowles	2906
13	Microtiter-Plate Assay of Nitric Oxide Synthase Activity 1999 ·Molecular Biotechnology ·John Dawson, Richard G. Knowles	16
14	3-Morpholino-Sydnonimine-Induced Suppression of Human Neutrophil Degranulation is Not Mediated by Cyclic GMP, Nitric Oxide or Peroxynitrite: Inhibition of the Increase in Intracellular Free Calcium Concentration by N-Morpholino- iminoacetonitrile, a Metabolite of 3-Morpholino-Sydnonimine 1997 ·Molecular Pharmacology ·Hannu Kankaanranta, Richard G. Knowles, Pauli Vuorinen, (unknown), Päivi Holm, Eeva Moilanen	18
15	1400W Is a Slow, Tight Binding, and Highly Selective Inhibitor of Inducible Nitric-oxide Synthase in Vitro and in Vivo breakdown → 1997 ·Journal of Biological Chemistry ·Edward P. Garvey, Jeffrey A. Oplinger, Eric S. Furfine, (unknown), Ferenc László, B.J.R. Whittle, Richard G. Knowles	727
16	THE role of indoleamine 2,3‐dioxygenase in the anti‐tumour activity of human interferon‐γ in vivo 1995 ·International Journal of Cancer ·Frances Burke, Richard G. Knowles, N East, Frances R. Balkwill	88
17	Endotoxin Causes Reciprocal Changes in Hepatic Nitric Oxide Synthesis, Gluconeogenesis, and Flux through Phosphoenolpyruvate Carboxykinase 1994 ·Biochemical and Biophysical Research Communications ·Robert A. Horton, Richard G. Knowles, M A Titheradge	27
18	Uptake of acetaminophen (paracetamol) by isolated rat liver cells 1993 ·Biochemical Pharmacology ·(unknown), Richard G. Knowles, Mark Salter, John A. Dawson, Brian Burchell, (unknown)	11
19	Measurement of glucuronidation by isolated rat liver cells using [14C]fructose 1992 ·Biochemical Pharmacology ·John A. Dawson, Richard G. Knowles, Christopher I. Pogson	4
20	Nitrovasodilators Have Proliferative as Well as Antiproliferative Effects 1991 ·Journal of Cardiovascular Pharmacology ·(unknown), Richard G. Knowles, Kamala D. Patel	11

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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