Duncan S. Holmes

1.5k citations

39 papers · 692 indexed · h-index 16

Molecular Biology
Organic Chemistry top 5%
Pharmacology
Immunology and Allergy top 10%
Computational Theory and Mathematics top 10%

Co-authors: Geert‐Jan Boons Mark J. Bamford John A. Robinson Jeremy C. Prodger Ann L. Walker V. Sáez Nicholas H. Rees Jeremy Kilburn
Topics: Carbohydrate Chemistry and Synthesis (8 papers)Glycosylation and Glycoproteins Research (7 papers)Allergic Rhinitis and Sensitization (5 papers)
Cited by: Biological Psychiatry Organic Chemistry Immunology and Allergy
Journals: Nature Communications Analytical Biochemistry Scientific Reports
Partner nations: United Kingdom France United States

In The Last Decade

Duncan S. Holmes

38 papers receiving 666 citations

Peers

Countries citing papers authored by Duncan S. Holmes

Since Specialization

Citations

This map shows the geographic impact of Duncan S. Holmes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Duncan S. Holmes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Duncan S. Holmes more than expected).

Fields of papers citing papers by Duncan S. Holmes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Duncan S. Holmes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Duncan S. Holmes. The network helps show where Duncan S. Holmes may publish in the future.

Co-authorship network of co-authors of Duncan S. Holmes

This figure shows the co-authorship network connecting the top 25 collaborators of Duncan S. Holmes. A scholar is included among the top collaborators of Duncan S. Holmes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Duncan S. Holmes. Duncan S. Holmes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Structure-based optimisation of orally active & reversible MetAP-2 inhibitors maintaining a tight ‘molecular budget’ 2020 ·Bioorganic & Medicinal Chemistry Letters ·David J. Hirst,Martín Brandt,Gordon Bruton,(unknown),Leanne Cutler,Nigel Deeks,(unknown),(unknown),Matthew Lindon,Afjal H. Miah,Kevin Page,(unknown),Lena Shukla,Martin Sims,Pamela J. Thomas,James H. Thorpe,Duncan S. Holmes	6
2	Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome 2019 ·Bioorganic & Medicinal Chemistry Letters ·Ann L. Walker,Ryan P. Bingham,(unknown),(unknown),Duncan S. Holmes,John Liddle,Oxana Polyakova,(unknown),Kathrine J. Smith,James H. Thorpe,(unknown),Gemma V. White,Robert J. Young,Alain Hovnanian	6
3	Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome 2019 ·Acta Crystallographica Section F Structural Biology Communications ·James H. Thorpe,(unknown),Kathrine J. Smith,Xiao Qing Lewell,(unknown),Gemma V. White,Oxana Polyakova,Pamela Nassau,Ann L. Walker,Duncan S. Holmes,Andrew C. Pearce,(unknown),John Liddle,Alain Hovnanian	2
4	Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors 2019 ·Bioorganic & Medicinal Chemistry Letters ·Ann L. Walker,Alexis Denis,Ryan P. Bingham,Anne Bouillot,(unknown),(unknown),Duncan S. Holmes,Alain Laroze,John Liddle,Marie-Hélène Fouchet,(unknown),(unknown),Andrew C. Pearce,Oxana Polyakova,Kathrine J. Smith,Pamela J. Thomas,James H. Thorpe,Lionel Trottet,(unknown),Alain Hovnanian	6
5	Identification, preclinical profile, and clinical proof of concept of an orally bioavailable pro‐drug of miridesap 2019 ·British Journal of Pharmacology ·Duncan Richards,Mark J. Bamford,Lia Liefaard,(unknown),Gareth Lewis,(unknown),Disala Fernando,(unknown),Douglas Thompson,Duncan S. Holmes	3
6	Design of Phthalazinone Amide Histamine H₁ Receptor Antagonists for Use in Rhinitis 2017 ·ACS Medicinal Chemistry Letters ·Panayiotis A. Procopiou,Alison J. Ford,(unknown),(unknown),Simon T. Hodgson,Duncan S. Holmes,Sadie Vile,Kenneth L. Clark,Ken Saunders,Robert J. Slack,James E. Rowedder,Clarissa J. Watts	12
7	Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase 2017 ·Nature Communications ·Jonathan P. Hutchinson,Paul Rowland,(unknown),(unknown),Carl Haslam,Clare I. Hobbs,Duncan S. Holmes,Paul Homes,John Liddle,Damian J. Mole,Iain Uings,Ann L. Walker,Scott P. Webster,Christopher G. Mowat,Chun‐wa Chung	37
8	In search of a small molecule agonist of the relaxin receptor RXFP1 for the treatment of liver fibrosis 2017 ·Scientific Reports ·Andrew McBride,Anna M. Hoy,Mark J. Bamford,Danuta E. Mossakowska,(unknown),Jeremy Griggs,(unknown),(unknown),(unknown),John P. Iredale,(unknown),Rebecca L. Aucott,Duncan S. Holmes,Scott P. Webster,Jonathan Fallowfield	22
9	The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis 2017 ·Bioorganic & Medicinal Chemistry Letters ·John Liddle,(unknown),Margaret Binnie,Anne Bouillot,Alexis Denis,Michael M. Hann,Carl Haslam,Duncan S. Holmes,(unknown),Michael Kranz,Andrew McBride,Olivier Mirguet,Damian J. Mole,Christopher G. Mowat,Sandeep Pal,Paul Rowland,Lionel Trottet,Iain Uings,Ann L. Walker,Scott P. Webster	9
10	Identification of selective 8-(piperidin-4-yloxy)quinoline sulfone and sulfonamide histamine H1 receptor antagonists for use in allergic rhinitis 2017 ·Bioorganic & Medicinal Chemistry Letters ·Panayiotis A. Procopiou,Alison J. Ford,(unknown),Ashley P. Hancock,Simon T. Hodgson,Duncan S. Holmes,(unknown),Sadie Vile,Kenneth L. Clark,Ken Saunders,Robert J. Slack,Clarissa J. Watts	2
11	The discovery of quinoline based single-ligand human H1 and H3 receptor antagonists 2016 ·Bioorganic & Medicinal Chemistry Letters ·Panayiotis A. Procopiou,(unknown),(unknown),Ashley P. Hancock,Simon T. Hodgson,Duncan S. Holmes,(unknown),(unknown),(unknown),James E. Rowedder,Robert J. Slack	6
12	Discovery of a Rapidly Metabolized, Long-Acting β₂Adrenergic Receptor Agonist with a Short Onset Time Incorporating a Sulfone Group Suitable for Once-Daily Dosing 2013 ·Journal of Medicinal Chemistry ·Panayiotis A. Procopiou,Victoria J. Barrett,Keith Biggadike,Peter R. Butchers,(unknown),Alison J. Ford,Stephen B. Guntrip,Duncan S. Holmes,(unknown),(unknown),(unknown),P. Jane Mutch,(unknown),(unknown),Claire Smith	20
13	Quinolines as a novel structural class of potent and selective PDE4 inhibitors: Optimisation for oral administration 2009 ·Bioorganic & Medicinal Chemistry Letters ·Michael D. Woodrow,Stuart P. Ballantine,Michael D. Barker,Michael Kranz,(unknown),Fiona S. Lucas,Margarete Neu,(unknown),Lisa E. Ranshaw,(unknown),(unknown),Duncan S. Holmes,Yemisi Solanke,Don O. Somers,Joanne Wiseman	54
14	p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression 2009 ·Journal of Medicinal Chemistry ·(unknown),Paul Bamborough,(unknown),(unknown),Duncan S. Holmes,Katherine L. Jones,Vipulkumar K. Patel,(unknown),D.O. Somers,Giovanni Vitulli,Ann L. Walker	35
15	Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity 2008 ·Bioorganic & Medicinal Chemistry Letters ·Richard Angell,(unknown),Paul Bamborough,Jacky B. Buckton,Stuart Cockerill,(unknown),(unknown),Duncan S. Holmes,Katherine L. Jones,Dramane I. Lainé,(unknown),(unknown),Kathryn J. Smith,Don O. Somers,Ann L. Walker	63
16	Quantification of the selective retention of palladium octabutoxynaphthalocyanine, a potential photothermal drug, in mouse tissues 2000 ·Journal of Photochemistry and Photobiology B Biology ·(unknown),Eva F. Gudgin Dickson,(unknown),Frank Fischer,Duncan S. Holmes,G. Jori,J. C. Kennedy,Malcolm E. Kenney,(unknown),R. Pottier,Glenn E. Weagle	14
17	Mimics of the sialyl Lewis X tetrasaccharide. Replacement of the N-Acetylglucosamine sugar with simple C2-symmetric 1,2-diols 1996 ·Bioorganic & Medicinal Chemistry ·Jeremy C. Prodger,Mark J. Bamford,Michael I. Bird,(unknown),Duncan S. Holmes,Richard Priest,V. Sáez	17
18	ChemInform Abstract: An Improved Method for the Synthesis of GDP‐Hexanolamine Derivatives, Key Reagents for the Purification and Characterization of Carbohydrate Processing Enzymes 1996 ·ChemInform ·Mark J. Bamford,(unknown),(unknown),(unknown),Duncan S. Holmes	2
19	Discovery and Analysis of a Series of C2-Symmetric HIV-1 Proteinase Inhibitors Derived from Penicillin 1994 ·Analytical Biochemistry ·Norman M. Gray,(unknown),N. Cammack,Kevin N. Cobley,Duncan S. Holmes,David C. Humber,David Orr,Charles R. Penn,Richard Pötter,Shalom Madar,Gordon G. Weingarten,Richard C. Bethell	0
20	Selection of a specifically blocked mutant of. Streptomyces cinnamonensis: Isolation and synthesis of 26-deoxymonensin A. 1989 ·The Journal of Antibiotics ·Doreen M. Ashworth,Duncan S. Holmes,John A. Robinson,Hideaki Oikawa,David E. Cane	13

About Duncan S. Holmes

Duncan S. Holmes is a scholar working on Immunology and Allergy, Biological Psychiatry and Behavioral Neuroscience, having authored 39 papers that have together received 692 indexed citations. Recurring topics across this work include Carbohydrate Chemistry and Synthesis (8 papers), Glycosylation and Glycoproteins Research (7 papers) and Allergic Rhinitis and Sensitization (5 papers). The work is most often cited by research in Biological Psychiatry (38 citations), Organic Chemistry (339 citations) and Immunology and Allergy (55 citations). Duncan S. Holmes has collaborated with scholars based in United Kingdom, France and United States. Frequent co-authors include Geert‐Jan Boons, Mark J. Bamford, John A. Robinson, Jeremy C. Prodger, Ann L. Walker, V. Sáez, Nicholas H. Rees, Jeremy Kilburn, David L. Turner and Paul Bamborough. Their work appears in journals such as Nature Communications, Analytical Biochemistry and Scientific Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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