James E. Rowedder

691 citations

19 papers · 460 indexed · h-index 9

Immunology and Allergy top 10%
- Cell Adhesion Molecules Research 10
- Allergic Rhinitis and Sensitization 2
Biotechnology top 10%
Molecular Biology
- PI3K/AKT/mTOR signaling in cancer 2
Cell Biology
Immunology
- Mast cells and histamine 2
Hematology
- Platelet Disorders and Treatments 4
Oncology
- Peptidase Inhibition and Analysis 4
Pulmonary and Respiratory Medicine
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis 3
Genetics
- Chronic Lymphocytic Leukemia Research 2

Co-authors: Koti Sreekrishna Marjorie A. Smith Jeffrey J. Clare Robert J. Slack Simon J. F. Macdonald John W. Barrett Panayiotis A. Procopiou John M. Pritchard
Cited by: Immunology and Allergy Biotechnology Molecular Biology
Journals: Journal of Medicinal Chemistry (7 papers)ACS Medicinal Chemistry Letters (3 papers)SLAS DISCOVERY (2 papers)
Partner nations: United Kingdom Ireland United States

In The Last Decade

James E. Rowedder

19 papers receiving 438 citations

Peers

Countries citing papers authored by James E. Rowedder

Since Specialization

Citations

This map shows the geographic impact of James E. Rowedder's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James E. Rowedder with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James E. Rowedder more than expected).

Fields of papers citing papers by James E. Rowedder

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James E. Rowedder. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James E. Rowedder. The network helps show where James E. Rowedder may publish in the future.

Co-authorship network

The 25 scholars most cited alongside James E. Rowedder, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James E. Rowedder Line = papers co-authored together James E. Rowedder links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	Discovery and Development of Highly Potent and Orally Bioavailable Nonpeptidic α_vβ₆ Integrin Inhibitors Journal of Medicinal Chemistry ·Panayiotis A. Procopiou,John W. Barrett,尾山竹滋,Richard J. D. Hatley,Ashley P. Hancock,John M. Pritchard,James E. Rowedder,Royston C. B. Copley,Robert J. Slack,Steven L. Sollis,J. E. Lim,D. S. Li,Simon J. F. Macdonald,何崇荣	2024	1
2	Core Modifications of GSK3335103 toward Orally Bioavailable α_vβ₆ Inhibitors with Improved Synthetic Tractability Journal of Medicinal Chemistry ·Reza Zarei,John W. Barrett,何崇荣,Glenn A. Burley,С.В. Кубиевич,Richard J. D. Hatley,Nicholas D. Measom,James A. Roper,James E. Rowedder,Robert J. Slack,Ratna Dumasari,Simon J. F. Macdonald	2024	3
3	A high-throughput MALDI-TOF MS biochemical screen for small molecule inhibitors of the antigen aminopeptidase ERAP1 SLAS DISCOVERY ·陈萍 CHEN Ping,Amy Burton,Alexis Pramberger,James E. Rowedder,Jonathan P. Hutchinson,Simon Peace,A. Prohaska,Melanie Leveridge,Roland S. Annan,Matthias Trost,Rachel E. Heap,María Emilia Dueñas	2022	8
4	Late‐Stage Functionalization by Chan–Lam Amination: Rapid Access to Potent and Selective Integrin Inhibitors Chemistry - A European Journal ·Edgar Misael,Keith Heidmann,James E. Rowedder,Sara G. Gardiner,Simon J. F. Macdonald,Stephen P. Argent,Jonathan D. Hirst,MA . Asril Marjohan,Christopher J. Moody	2020	9
5	Discovery of the first potent and selective αvβ5 integrin inhibitor based on an amide-containing core European Journal of Medicinal Chemistry ·D. S. Li,John W. Barrett,Sandeep Pal,James E. Rowedder,John A. Murphy,何崇荣	2020	8
6	Design and Development of a Macrocyclic Series Targeting Phosphoinositide 3-Kinase δ ACS Medicinal Chemistry Letters ·周桂香,G. Pantziou,焦爽,Chun‐wa Chung,M.A. Convery,Semenova,Craig Jamieson,David N. Mallett,James E. Rowedder,Paul Rowland,Daniel A. Thomas,ಶಲ್ಟ್. ಓ.ಆರ್. ಹರಿಚೆ	2020	9
7	Profile of a Highly Selective Quaternized Pyrrolidine Betaine α_vβ₆ Integrin Inhibitor—(3S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((1S and 1R,3R)-1-methyl-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate Synthesized by Stereoselective Methylation Journal of Medicinal Chemistry ·何崇荣,Selda BAYBO,Daniel Barker,Panayiotis A. Procopiou,Ana Paula Costa,John W. Barrett,Joelle Le,Sean M. Lynn,Péter Pogány,Cassie Pratley,John M. Pritchard,James A. Roper,James E. Rowedder,Robert J. Slack,Giovanni Vitulli,Simon J. F. Macdonald,William J. Kerr	2019	6
8	The Design of Potent, Selective and Drug‐Like RGD αvβ1 Small‐Molecule Inhibitors Derived from non‐RGD α4β1 Antagonists ChemMedChem ·Richard J. D. Hatley,何崇荣,Robert J. Slack,Edith Mbanga,S. Vijay Aswath,Anna Gruszka,Yoshiaki Washio,James E. Rowedder,Péter Pogány,Sandeep Pal,Simon J. F. Macdonald	2019	6
9	Discovery of an Orally Bioavailable Pan αv Integrin Inhibitor for Idiopathic Pulmonary Fibrosis Journal of Medicinal Chemistry ·Niall A. Anderson,Sébastien Campos,Nurul Afiqah Nordin,Royston C. B. Copley,В. Г. Привалова,Stephen A. Harrison,Joelle Le,Katarzyna Ray,Harvey Friedrich,John M. Pritchard,James E. Rowedder,Claire Smith,P. van Arkel,Giovanni Vitulli,Simon J. F. Macdonald	2019	8
10	Discovery of (S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic α_vβ₆ Integrin Inhibitor for the Inhaled Treatment of Idiopathic Pulmonary Fibrosis Journal of Medicinal Chemistry ·Panayiotis A. Procopiou,Niall A. Anderson,John W. Barrett,何崇荣,尾山竹滋,Brendan J. Fallon,Ashley P. Hancock,Joelle Le,Paul Mugisha,Richard P. Marshall,Katherine Howlett,John M. Pritchard,James E. Rowedder,Sole Molander,Robert J. Slack,Steven L. Sollis,Colin J. Suckling,J. E. Lim,Giovanni Vitulli,Simon J. F. Macdonald	2018	31
11	Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3-Kinase δ through a Deconstruction and Regrowth Approach Journal of Medicinal Chemistry ·焦爽,M.A. Convery,Anthony W. J. Cooper,Kenneth Down,J. Hamblin,Graham G. A. Inglis,Simon Peace,James E. Rowedder,Paul Rowland,Selda BAYBO,Tetiana Savchenko	2018	10
12	Design of Phthalazinone Amide Histamine H₁ Receptor Antagonists for Use in Rhinitis ACS Medicinal Chemistry Letters ·Panayiotis A. Procopiou,Alison J. Ford,David Ayo Olubunmi,Benoît Reynier,Simon T. Hodgson,Duncan S. Holmes,Sadie Vile,Kenneth L. Clark,Ken Saunders,Robert J. Slack,James E. Rowedder,Clarissa J. Watts	2017	12
13	Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C–C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinase δ (PI3Kδ) Inhibitors Journal of Medicinal Chemistry ·Hao Yan-ron,Barrie Kellam,W. A. Zajc,Stephen J. Hill,Nicholas D. Kindon,Tracey D. Bradshaw,Jin Li,Simon J. F. Macdonald,James E. Rowedder,Leigh A. Stoddart,Michael J. Stocks	2017	8
14	Determining the True Selectivity Profile of αv Integrin Ligands Using Radioligand Binding: Applying an Old Solution to a New Problem SLAS DISCOVERY ·James E. Rowedder,Anayle Statuti,Robert J. Slack	2017	14
15	The discovery of quinoline based single-ligand human H1 and H3 receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Panayiotis A. Procopiou,Diana Rozo Montaño,David Ayo Olubunmi,Ashley P. Hancock,Simon T. Hodgson,Duncan S. Holmes,Yu Tao,Benoît Reynier,E. N. Oberemok,James E. Rowedder,Robert J. Slack	2016	6
16	Relative Binding Affinities of Integrin Antagonists by Equilibrium Dialysis and Liquid Chromatography–Mass Spectrometry ACS Medicinal Chemistry Letters ·William J. Tipping,祎婧王,James Truslow Adams,P Forey,James E. Rowedder,M. Jonathan Fray,MA . Asril Marjohan,Simon J. F. Macdonald,Neil J. Oldham	2014	5
17	Pyrazolopyridazine alpha-2-delta-1 ligands for the treatment of neuropathic pain Bioorganic & Medicinal Chemistry Letters ·A.A. Zhukova,Mark P. Healy,Gianpaolo Bravi,Andrew Billinton,Christopher N. Johnson,Kim L. Matthews,Karamjit S. Jandu,Wenjing Meng,Anne Hersey,David G. Livermore,Arlo Jung,Jason Witherington,Rino A. Bit,James E. Rowedder,Jason Brown,Nick M. Clayton	2010	12
18	Direct Measurement of the Binding of RAS to Neurofibromin Using a Scintillation Proximity Assay Analytical Biochemistry ·Richard Skinner,Mauro Picardo,David Billings,Neil D. Cook,Nurafifah Sahib,James E. Rowedder,Peter N. Lowe	1994	22
19	Production of mouse epidermal growth factor in yeast: high-level secretion using Pichia pastoris strains containing multiple gene copies Gene ·Jeffrey J. Clare,J A Lafogiannis,M. Colombo,James E. Rowedder,Marjorie A. Smith,Tian Ze Wang,Koti Sreekrishna,Manuella Faith Amoako	1991	282

About James E. Rowedder

James E. Rowedder is a scholar working on Immunology and Allergy, Hematology and Genetics, having authored 19 papers that have together received 460 indexed citations. Recurring topics across this work include Cell Adhesion Molecules Research (10 papers), Platelet Disorders and Treatments (4 papers), Peptidase Inhibition and Analysis (4 papers), Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis (3 papers), Chronic Lymphocytic Leukemia Research (2 papers), Allergic Rhinitis and Sensitization (2 papers), PI3K/AKT/mTOR signaling in cancer (2 papers) and Mast cells and histamine (2 papers). The work is most often cited by research in Immunology and Allergy (58 citations), Biotechnology (60 citations) and Molecular Biology (299 citations). James E. Rowedder has collaborated with scholars based in United Kingdom, Ireland and United States. Frequent co-authors include Koti Sreekrishna, Marjorie A. Smith, Jeffrey J. Clare, Robert J. Slack, Simon J. F. Macdonald, John W. Barrett, Panayiotis A. Procopiou, John M. Pritchard, Mauro Picardo and Peter N. Lowe. Their work appears in journals such as Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, SLAS DISCOVERY, Bioorganic & Medicinal Chemistry Letters and European Journal of Medicinal Chemistry.

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