D.O. Somers

1.6k citations

18 papers · 1.2k indexed · h-index 14

Virology top 2%
- HIV Research and Treatment 4
Infectious Diseases top 5%
- HIV/AIDS drug development and treatment 6
Computational Theory and Mathematics top 5%
Molecular Biology
- Biochemical and Molecular Research 4
- Melanoma and MAPK Pathways 3
Organic Chemistry top 10%
Materials Chemistry
- Enzyme Structure and Function 4
Clinical Biochemistry
- Metabolism and Genetic Disorders 3
Hepatology
- Hepatitis C virus research 3
Biochemistry
- Amino Acid Enzymes and Metabolism 2

Co-authors: D.K. Stammers E. Yvonne Jones David I. Stuart Carl Ross Elspeth F. Garman Robert Esnouf J.N. Champness Aniruddha Achari
Cited by: Virology Infectious Diseases Computational Theory and Mathematics
Journals: Bioorganic & Medicinal Chemistry Letters (3 papers)Organic Letters (2 papers)Journal of Medicinal Chemistry (2 papers)
Partner nations: United Kingdom United States Ireland

In The Last Decade

D.O. Somers

18 papers receiving 1.2k citations

Peers

Countries citing papers authored by D.O. Somers

Since Specialization

Citations

This map shows the geographic impact of D.O. Somers's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by D.O. Somers with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites D.O. Somers more than expected).

Fields of papers citing papers by D.O. Somers

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by D.O. Somers. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by D.O. Somers. The network helps show where D.O. Somers may publish in the future.

Co-authorship network

The 25 scholars most cited alongside D.O. Somers, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with D.O. Somers Line = papers co-authored together D.O. Somers links everyone, so they are left out of the graph.

All Works

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18 of 18 papers shown

#	Work
1	Discovery of potent and selective Spleen Tyrosine Kinase inhibitors for the topical treatment of inflammatory skin disease Bioorganic & Medicinal Chemistry Letters ·Michael D. Barker,John Liddle,Francis Atkinson,David M. Wilson,Marion C. Dickson,César Ramírez-Molina,Huw D. Lewis,H. Paul Breslin,D.O. Somers,Margarete Neu,Emma J. Jones,Robert J. Watson	2018	18
2	Structurally Diverse Mitochondrial Branched Chain Aminotransferase (BCATm) Leads with Varying Binding Modes Identified by Fragment Screening Journal of Medicinal Chemistry ·Alan D. Borthwick,Nicolas Ancellin,Sophie M. Bertrand,Ryan P. Bingham,Paul S. Carter,Chun‐wa Chung,Ian Churcher,Nérina Dodic,hejimohammad norouzi,Peter Francis,Barayuwa Mununggurr,Craig Jamieson,Stephen D. Pickett,Sarah E. Smith,D.O. Somers,Claus Spitzfaden,Colin J. Suckling,Robert J. Young	2016	27
3	CSAR 2014: A Benchmark Exercise Using Unpublished Data from Pharma Journal of Chemical Information and Modeling ·Heather A. Carlson,Richard D. Smith,Kelly L. Damm‐Ganamet,Jeanne A. Stuckey,Aqeel Ahmed,M.A. Convery,D.O. Somers,Michael Kranz,P.A. Elkins,Guanglei Cui,Catherine E. Peishoff,Millard H. Lambert,James B. Dunbar	2016	82
4	Identification of a Novel and Selective Series of Itk Inhibitors via a Template-Hopping Strategy ACS Medicinal Chemistry Letters ·Catherine M. Alder,M Rennella,Amanda Campbell,Fatima Elkabti,Angela M. Deakin,John D. Harling,Carol Harris,Murat Kekili,Sean M. Lynn,Aoife C. Maxwell,Carl Ittameier,Roberto Clark,Onkar Singh,Ian E. Smith,D.O. Somers,竹有章,Gareth Wayne,Caroline Wilson,James M. Woolven	2013	16
5	p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression Journal of Medicinal Chemistry ·Mike Sparkes,Paul Bamborough,P L Knox,Semenova,Duncan S. Holmes,Katherine L. Jones,Vipulkumar K. Patel,Sun Fei,D.O. Somers,Giovanni Vitulli,Ann L. Walker	2009	35
6	Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode Bioorganic & Medicinal Chemistry Letters ·Richard Angell,Paul Bamborough,Anne Cleasby,Stuart Cockerill,Katherine L. Jones,Christopher J. Mooney,D.O. Somers,Ann L. Walker	2007	32
7	N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)amides as potent, selective, inhibitors of JNK2 and JNK3 Bioorganic & Medicinal Chemistry Letters ·Richard Angell,Francis Atkinson,Murray J. B. Brown,Tsu Tshen Chuang,J.A. Christopher,Chen Hong-p,Nagham Yassin Ahmed,Kendra E. Hightower,В. А. Мелкий,K. Lindner,Margarete Neu,Paul Rowland,Robyn Shea,Jeffery L. Smith,D.O. Somers,DS Nok Afifah,W. Carton,Ruolan Wang	2006	70
8	Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 Urea Leads to Potent Intracellular Inhibitors of Hepatitis C Virus NS3/4A Protease Organic Letters ·Martin J. Slater,Elizabeth M. Amphlett,David Andrews,Paul Bamborough,Heather Won Tesoriero,Martin R. Johnson,Paul S. Jones,Erllens Éder Silva,N. R. Parry,D.O. Somers,Alan J. Stewart,Tadeusz Skarżyński	2003	11
9	Pyrrolidine-5,5-trans-lactams. 2. The Use of X-ray Crystal Structure Data in the Optimization of P3 and P4 Substituents Organic Letters ·David Andrews,G. Panariello,Yuhei Onishi,Andrew C. Good,Luis Angel Sandoval Astudillo,Martin R. Johnson,Paul S. Jones,Erllens Éder Silva,John Robinson,Tadeusz Skarżyński,Martin J. Slater,D.O. Somers	2002	11
10	2.0 Å X‐ray structure of the ternary complex of 7,8‐dihydro‐6‐hydroxymethylpterinpyrophosphokinase from Escherichia coli with ATP and a substrate analogue FEBS Letters ·D.K. Stammers,Aniruddha Achari,D.O. Somers,よしこみわ,Leonardo Gónzalez-Galli,David L. Scott,J.N. Champness	1999	48
11	Continuous and Discontinuous Changes in the Unit Cell of HIV-1 Reverse Transcriptase Crystals on Dehydration Acta Crystallographica Section D Biological Crystallography ·Robert Esnouf,Jingshan Ren,Elspeth F. Garman,D.O. Somers,Carl Ross,E. Yvonne Jones,D.K. Stammers,David I. Stuart	1998	44
12	Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase Nature Structural Biology ·Aniruddha Achari,D.O. Somers,J.N. Champness,よしこみわ,Leonardo Gónzalez-Galli,D.K. Stammers	1997	236
13	High resolution structures of HIV-1 RT from four RT–inhibitor complexes Nature Structural & Molecular Biology ·Jingshan Ren,Robert Esnouf,Elspeth F. Garman,D.O. Somers,Carl Ross,Ian Kirby,James Keeling,G. Darby,E. Yvonne Jones,David I. Stuart,D.K. Stammers	1995	437
14	Crystals of HIV-1 Reverse Transcriptase Diffracting to 2·2 Å Resolution Journal of Molecular Biology ·D.K. Stammers,D.O. Somers,Carl Ross,Ilsa T. Kirby,Pampa Ray,Pradip Harishchandra Bhosale,Mark H. Norman,YueJun Hao,Robert Esnouf,Elspeth F. Garman,E. Yvonne Jones,David I. Stuart	1994	54
15	The growth and characterization of crystals of human immunodeficiency virus (HIV) reverse transcriptase Journal of Crystal Growth ·E. Yvonne Jones,David I. Stuart,Elspeth F. Garman,Kelvin Phua Cheng Pau,D.C. Phillips,G.L. Taylor,O. Matsumoto,G. Darby,Brendan Larder,Denise M. Lowe,K. L. Powell,D. J. M. Purifoy,Carl Ross,D.O. Somers,Margaret Tisdale,D.K. Stammers	1993	6
16	Sheep 6-phosphogluconate dehydrogenase. Revised protein sequence based upon the sequences of cDNA clones obtained with the polymerase chain reaction Biochemical Journal ·D.O. Somers,S M Medd,John E. Walker,Margaret Adams	1992	17
17	A two-step purification procedure for sheep liver 6-phosphogluconate dehydrogenase Protein Expression and Purification ·D.O. Somers,János Hajdu,Margaret Adams	1991	3
18	The structure of 6-phosphogluconate dehydrogenase refined at 2.5 Å resolution Acta Crystallographica Section B Structural Science ·Margaret Adams,S. Gover,Hayden Cash,Christopher Phillips,D.O. Somers	1991	32

About D.O. Somers

D.O. Somers is a scholar working on Virology, Clinical Biochemistry and Hepatology, having authored 18 papers that have together received 1.2k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (6 papers), HIV Research and Treatment (4 papers), Biochemical and Molecular Research (4 papers), Enzyme Structure and Function (4 papers), Metabolism and Genetic Disorders (3 papers), Melanoma and MAPK Pathways (3 papers), Hepatitis C virus research (3 papers) and Amino Acid Enzymes and Metabolism (2 papers). The work is most often cited by research in Virology (381 citations), Infectious Diseases (537 citations) and Computational Theory and Mathematics (166 citations). D.O. Somers has collaborated with scholars based in United Kingdom, United States and Ireland. Frequent co-authors include D.K. Stammers, E. Yvonne Jones, David I. Stuart, Carl Ross, Elspeth F. Garman, Robert Esnouf, J.N. Champness, Aniruddha Achari, Jingshan Ren and James Keeling. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Organic Letters, Journal of Medicinal Chemistry, Journal of Crystal Growth and ACS Medicinal Chemistry Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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