Douglas S. Darling

8.2k citations

90 papers · 6.5k indexed · 2 hit papers · h-index 41

Molecular Biology top 1%
Genetics top 1%
Oncology top 2%
Cancer Research top 1%
Endocrinology, Diabetes and Metabolism top 0.5%

Co-authors: William W. Chin Mitchell A. Lazar Richard A. Hodin Joan Burnside Douglas C. Dean Yongqing Liu Antonio Postigo Yujiro Higashi
Topics: Estrogen and related hormone effects (21 papers)Thyroid Disorders and Treatments (18 papers)Glycosylation and Glycoproteins Research (11 papers)
Cited by: Cancer Research Endocrinology, Diabetes and Metabolism Molecular Biology
Journals: Science Proceedings of the National Academy of Sciences Nucleic Acids Research
Partner nations: United States Spain Japan

In The Last Decade

Douglas S. Darling

88 papers receiving 6.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

2009 1.4k citations Douglas S. Darling et al. profile →
EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness

2012 426 citations Ester Sànchez‐Tilló, Oriol de Barrios et al. profile →

Peers

Countries citing papers authored by Douglas S. Darling

Since Specialization

Citations

This map shows the geographic impact of Douglas S. Darling's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Douglas S. Darling with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Douglas S. Darling more than expected).

Fields of papers citing papers by Douglas S. Darling

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Douglas S. Darling. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Douglas S. Darling. The network helps show where Douglas S. Darling may publish in the future.

Co-authorship network of co-authors of Douglas S. Darling

This figure shows the co-authorship network connecting the top 25 collaborators of Douglas S. Darling. A scholar is included among the top collaborators of Douglas S. Darling based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Douglas S. Darling. Douglas S. Darling is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas 2023 ·JCI Insight ·Ester Sànchez‐Tilló,Leire Pedrosa,(unknown),(unknown),Balázs Győrffy,Lidia Sánchez-Moral,Laura Siles,Juan José Lozano,Anna Esteve‐Codina,Douglas S. Darling,Míriam Cuatrecasas,Antoni Castells,Joan Maurel,Antonio Postigo	7
2	ZEB1 promotes inflammation and progression towards inflammation-driven carcinoma through repression of the DNA repair glycosylase MPG in epithelial cells 2019 ·Gut ·Oriol de Barrios,Lidia Sánchez-Moral,Marlies Cortés,(unknown),(unknown),(unknown),Laura Siles,Rosa del Campo,María Jesús Fernández‐Aceñero,Douglas S. Darling,Antoni Castells,Joan Maurel,Azucena Salas,Douglas C. Dean,Antonio Postigo	42
3	Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance 2017 ·Oncogene ·Kelly A. Whelan,Prasanna M. Chandramouleeswaran,Koji Tanaka,Mitsuteru Natsuizaka,Manti Guha,Satish Srinivasan,Douglas S. Darling,Yoshiaki Kita,Shoji Natsugoe,Jeffrey D. Winkler,Andres J. Klein–Szanto,Ravi K. Amaravadi,Narayan G. Avadhani,Anil K. Rustgi,Hiroshi Nakagawa	75
4	ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1 2016 ·Gut ·Oriol de Barrios,Balázs Győrffy,María Jesús Fernández‐Aceñero,Ester Sànchez‐Tilló,Lidia Sánchez-Moral,Laura Siles,(unknown),Gaël Roué,J. Ignacio Casal,Douglas S. Darling,Antoni Castells,Antonio Postigo	32
5	A Systems Biology Approach Identifies a Regulatory Network in Parotid Acinar Cell Terminal Differentiation 2015 ·PLoS ONE ·(unknown),(unknown),Jaganathan Lakshmanan,(unknown),(unknown),(unknown),Savitri Appana,Guy Brock,James L. Wittliff,Douglas S. Darling	9
6	ZEB1 Promotes Invasiveness of Colorectal Carcinoma Cells through the Opposing Regulation of uPA and PAI-1 2013 ·Clinical Cancer Research ·Ester Sànchez‐Tilló,Oriol de Barrios,Laura Siles,(unknown),Douglas S. Darling,Míriam Cuatrecasas,Antoni Castells,Antonio Postigo	55
7	Model Discrimination in Dynamic Molecular Systems: Application to Parotid De-differentiation Network 2013 ·Journal of Computational Biology ·Jaejik Kim,Jiaxu Li,(unknown),Douglas S. Darling,Grzegorz A. Rempała	4
8	A NOTCH3-Mediated Squamous Cell Differentiation Program Limits Expansion of EMT-Competent Cells That Express the ZEB Transcription Factors 2011 ·Cancer Research ·Shinya Ohashi,Mitsuteru Natsuizaka,Seiji Naganuma,Shingo Kagawa,(unknown),Hiroshi Itoh,Ross A. Kalman,Momo Nakagawa,Douglas S. Darling,Devraj Basu,Phyllis A. Gimotty,Andres J. Klein–Szanto,J. Alan Diehl,Meenhard Herlyn,Hiroshi Nakagawa	89
9	Cell Type–Specific Transcriptome Analysis Reveals a Major Role for Zeb1 and miR-200b in Mouse Inner Ear Morphogenesis 2011 ·PLoS Genetics ·Ronna Hertzano,Ran Elkon,Kiyoto Kurima,(unknown),(unknown),Michelle A. Sallin,(unknown),Douglas S. Darling,Andrew J. Griffith,David J. Eisenman,Scott E. Strome	67
10	Analysis of Zfhx1a mutant mice reveals palatal shelf contact-independent medial edge epithelial differentiation during palate fusion 2008 ·Cell and Tissue Research ·(unknown),Qun Li,Yujiro Higashi,Douglas S. Darling,Jixiang Ding	28
11	ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease 2008 ·Modern Pathology ·Meenakshi Singh,Nicole S. Spoelstra,Annie Jean,Erin N. Howe,Kathleen C. Torkko,(unknown),Douglas S. Darling,Kenneth R. Shroyer,Kathryn B. Horwitz,Russell R. Broaddus,Jennifer K. Richer	117
12	Helicobacter pylori infection in people who are intellectually and developmentally disabled: A review 2007 ·Special Care in Dentistry ·(unknown),Catherine J. Binkley,(unknown),Douglas S. Darling	16
13	Isoproterenol increases sorting of parotid gland cargo proteins to the basolateral pathway 2007 ·American Journal of Physiology-Cell Physiology ·(unknown),(unknown),Sven‐Ulrik Gorr,Douglas S. Darling	9
14	MUC1 splice variants in human ocular surface tissues: Possible differences between dry eye patients and normal controls 2006 ·Experimental Eye Research ·(unknown),Douglas S. Darling,Marcia M. Jumblatt,Gary N. Foulks,(unknown),(unknown),William W. Young	51
15	Expression of Zfhep/δEF1 protein in palate, neural progenitors, and differentiated neurons 2003 ·Gene Expression Patterns ·Douglas S. Darling,(unknown),(unknown),(unknown),(unknown)	42
16	Cell-specific phosphorylation of Zfhep transcription factor 2002 ·Biochemical and Biophysical Research Communications ·(unknown),(unknown),Gregory E. Smith,Douglas S. Darling	31
17	Thyroid Hormone Receptor Mutations that Interfere with Transcriptional Activation also Interfere with Receptor Interaction with a Nuclear Protein 1991 ·Molecular Endocrinology ·(unknown),Evan D. Rosen,Douglas S. Darling,Ronald J. Koenig	84
18	Basal and Thyroid Hormone Receptor Auxiliary Protein- Enhanced Binding of Thyroid Hormone Receptor Isoforms to Native Thyroid Hormone Response Elements 1991 ·Endocrinology ·Paul M. Yen,Douglas S. Darling,William W. Chin	8
19	Effects of triiodothyronine and propylthiouracil on thyroid function and smoltification of coho salmon (Oncorhynchus kisutch) 1987 ·Fish Physiology and Biochemistry ·Craig V. Sullivan,Douglas S. Darling,Walton W. Dickhoff	20
20	Thyroid Function during Smoltification of Salmonid Fish 1982 ·Walton W. Dickhoff,Douglas S. Darling,Aubrey Gorbman	30

About Douglas S. Darling

Douglas S. Darling is a scholar working on Endocrinology, Diabetes and Metabolism, Genetics and Molecular Biology, having authored 90 papers that have together received 6.5k indexed citations. Recurring topics across this work include Estrogen and related hormone effects (21 papers), Thyroid Disorders and Treatments (18 papers) and Glycosylation and Glycoproteins Research (11 papers). The work is most often cited by research in Cancer Research (1.4k citations), Endocrinology, Diabetes and Metabolism (1.3k citations) and Molecular Biology (4.1k citations). Douglas S. Darling has collaborated with scholars based in United States, Spain and Japan. Frequent co-authors include William W. Chin, Mitchell A. Lazar, Richard A. Hodin, Joan Burnside, Douglas C. Dean, Yongqing Liu, Antonio Postigo, Yujiro Higashi, Laura Siles and Ronald J. Koenig. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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