Dirk E. Smith

9.8k citations

48 papers · 7.3k indexed · 4 hit papers · h-index 33

Immunology top 0.2%
- IL-33, ST2, and ILC Pathways 23
- Immune Cell Function and Interaction 9
- Immune Response and Inflammation 9
Immunology and Allergy top 2%
- Allergic Rhinitis and Sensitization 4
Dermatology top 1%
Physiology top 2%
- Asthma and respiratory diseases 11
Surgery top 1%
- Eosinophilic Esophagitis 12
Molecular Biology
- Inflammasome and immune disorders 5
Hematology
- Autoimmune and Inflammatory Disorders Research 3

Co-authors: John E. Sims Michael R. Comeau Marilyn M. Cornwell Zoulfia Allakhverdi Guy Delespesse Dale T. Umetsu Molly D. Smithgall Ya‐Jen Chang
Cited by: Immunology Immunology and Allergy Dermatology
Journals: Journal of Biological Chemistry (7 papers)Journal of Allergy and Clinical Immunology (4 papers)Immunity (2 papers)
Partner nations: United States Canada United Kingdom

In The Last Decade

Dirk E. Smith

46 papers receiving 7.2k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2011 Nature Immunology
2010 Nature reviews. Immunology
2008 International Immunology
2001 Nature

Peers

Countries citing papers authored by Dirk E. Smith

Since Specialization

Citations

This map shows the geographic impact of Dirk E. Smith's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Dirk E. Smith with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Dirk E. Smith more than expected).

Fields of papers citing papers by Dirk E. Smith

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Dirk E. Smith. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Dirk E. Smith. The network helps show where Dirk E. Smith may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Dirk E. Smith, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Dirk E. Smith Line = papers co-authored together Dirk E. Smith links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Activating transcription factor 3 regulates hepatic apolipoprotein A4 upon metabolic stress Journal of Biological Chemistry ·Philippe Coffre,Dirk E. Smith,Joseph Choi,Joseph Scafidi,Michael J. Wolfgang	2025	0
2	IL-33 promotes gastrointestinal allergy in a TSLP-independent manner Mucosal Immunology ·Heejae Han,Florence Roan,Laura K. Johnston,Dirk E. Smith,Paul Bryce,Steven F. Ziegler	2017	62
3	IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis American Journal Of Pathology ·Carlo De Salvo,F. Leonarski,Luca Pastorelli,Benedetta Mattioli,Sara Omenetti,Ashma Taqiyyah,Guodong Lv,Rekha Garg,Wendy A. Goodman,Alexander Rodriguez‐Palacios,Dirk E. Smith,Derek W. Abbott,Fabio Cominelli,Giorgos Bamias,Wei Xin,James J. Lee,Maurizio Vecchi,Theresa T. Pizarro	2016	66
4	The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm American Journal of Respiratory Cell and Molecular Biology ·Jeremy A. Hirota,Matthew J. Gold,Paul Hiebert,Leigh G. Parkinson,Sayyidah Hafidzotul Asroriyah,Dirk E. Smith,Philip M. Hansbro,Chris Carlsten,加川貴俊,Don D. Sin,Kelly M. McNagny,Darryl A. Knight	2014	75
5	Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33 Journal of Allergy and Clinical Immunology ·Ying Lai,William A. Altemeier,住田旭,Adrian M. Piliponsky,Brian Johnson,Cara L. Appel,Charles W. Frevert,Dallas M. Hyde,Steven F. Ziegler,Dirk E. Smith,William R. Henderson,Michael H. Gelb,Teal S. Hallstrand	2013	50
6	Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection The Journal of Experimental Medicine ·Marsha Wills‐Karp,Reena Rani,Krista Dienger,Ian Lewkowich,James G. Fox,Charles Perkins,Mária Héder-Rima,Fred D. Finkelman,Dirk E. Smith,Paul Bryce,Evelyn A. Kurt‐Jones,Timothy C. Wang,Umasundari Sivaprasad,Gurjit K. Khurana Hershey,De’Broski R. Herbert	2012	155
7	Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity Journal of Allergy and Clinical Immunology ·Hye Young Kim,Ya‐Jen Chang,Srividya Subramanian,Hyun-Hee Lee,Lee A. Albacker,Ponpan Matangkasombut,Paul B. Savage,Andrew N. J. McKenzie,Dirk E. Smith,James B. Rottman,Rosemarie H. DeKruyff,Dale T. Umetsu	2011	265
8	Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunitybreakdown → Nature Immunology ·Ya‐Jen Chang,Hye Young Kim,Lee A. Albacker,Nicole Baumgarth,Andrew N. J. McKenzie,Dirk E. Smith,Rosemarie H. DeKruyff,Dale T. Umetsu	2011	640
9	Neuron-Specific Effects of Interleukin-1β Are Mediated by a Novel Isoform of the IL-1 Receptor Accessory Protein Journal of Neuroscience ·Yangyang Huang,Dirk E. Smith,Osvaldo Ibáñez-Sandoval,John E. Sims,Wilma Friedman	2011	136
10	Effector Function of CD34+ Hemopoietic Progenitor Cells in Allergic Inflammation Journal of Allergy and Clinical Immunology ·Zoulfia Allakhverdi,Michael R. Comeau,Dirk E. Smith,Dean Toy,Léandra Mfuna Endam,Martin Desrosiers,Evita Intan Susanti,Judah A. Denburg,B. Stainsby,G Delespesse	2009	1
11	A Central Nervous System-Restricted Isoform of the Interleukin-1 Receptor Accessory Protein Modulates Neuronal Responses to Interleukin-1 Immunity ·Dirk E. Smith,Brian P. Lipsky,Chris B. Russell,Randal R. Ketchem,Jacqueline Kirchner,Kelly Hensley,Yangyang Huang,Wilma Friedman,Vincent Boissonneault,Marie-Michèle Plante,Serge Rivest,John E. Sims	2009	101
12	IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cellsbreakdown → International Immunology ·Molly D. Smithgall,Michael R. Comeau,Bo Ruem Yoon,David R. Kaufman,Richard Armitage,Dirk E. Smith	2008	516
13	The IL-1 receptor accessory protein (AcP) is required for IL-33 signaling and soluble AcP enhances the ability of soluble ST2 to inhibit IL-33 Cytokine ·Gaby Palmer,Brian P. Lipsky,Molly D. Smithgall,David Meininger,Sophia Siu,Dominique Talabot‐Ayer,Cem Gabay,Dirk E. Smith	2008	150
14	Cutting Edge: The ST2 Ligand IL-33 Potently Activates and Drives Maturation of Human Mast Cells The Journal of Immunology ·Zoulfia Allakhverdi,Dirk E. Smith,Michael R. Comeau,Guy Delespesse	2007	418
15	The Soluble Form of IL-1 Receptor Accessory Protein Enhances the Ability of Soluble Type II IL-1 Receptor to Inhibit IL-1 Action Immunity ·Dirk E. Smith,Roberta Hanna,Della Friend,Heather M. Moore,Hongbo Chen,Ann M. Farese,Thomas J. MacVittie,G. Duke Virca,John E. Sims	2003	147
16	Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transductionbreakdown → Nature ·Katherine A. Fitzgerald,Eva M. Pålsson‐McDermott,Andrew Bowie,Caroline A. Jefferies,Ashley Mansell,Gareth Brady,Elizabeth Brint,Aisling Dunne,Pearl Gray,Mary T. Harte,Franci Vosloo,Dirk E. Smith,John E. Sims,Timothy A. Bird,Luke O'neill	2001	1006
17	Four New Members Expand the Interleukin-1 Superfamily Journal of Biological Chemistry ·Dirk E. Smith,Blair R. Renshaw,Randal R. Ketchem,Marek Kubin,Kirsten E. Garka,John E. Sims	2000	275
18	Identification and Characterization of Two Members of a Novel Class of the Interleukin-1 Receptor (IL-1R) Family Journal of Biological Chemistry ·Teresa L. Born,Dirk E. Smith,Kirsten E. Garka,Blair R. Renshaw,哲夫内藤,John E. Sims	2000	88
19	Fibroblast Responses to Cytokines Are Maintained During Aging Annals of Plastic Surgery ·M D GARDINER,Soverin Karmiol,Mark McKain,Daniel P. Normolle,Dirk E. Smith,W.L. Garner	1995	22
20	Phylogenetic Inferences on the Relationship of North American and European Picea Species Based on Nuclear Ribosomal 18S Sequences and the Internal Transcribed Spacer 1 Region Molecular Phylogenetics and Evolution ·Dirk E. Smith,Anita S. Klein	1994	30

About Dirk E. Smith

Dirk E. Smith is a scholar working on Immunology, Immunology and Allergy and Physiology, having authored 48 papers that have together received 7.3k indexed citations. Recurring topics across this work include IL-33, ST2, and ILC Pathways (23 papers), Eosinophilic Esophagitis (12 papers), Asthma and respiratory diseases (11 papers), Immune Cell Function and Interaction (9 papers), Immune Response and Inflammation (9 papers), Inflammasome and immune disorders (5 papers), Allergic Rhinitis and Sensitization (4 papers) and Autoimmune and Inflammatory Disorders Research (3 papers). The work is most often cited by research in Immunology (5.3k citations), Immunology and Allergy (347 citations) and Dermatology (448 citations). Dirk E. Smith has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include John E. Sims, Michael R. Comeau, Marilyn M. Cornwell, Zoulfia Allakhverdi, Guy Delespesse, Dale T. Umetsu, Molly D. Smithgall, Ya‐Jen Chang, Lee A. Albacker and Rosemarie H. DeKruyff. Their work appears in journals such as Journal of Biological Chemistry, Journal of Allergy and Clinical Immunology, Immunity, Clinical & Experimental Allergy and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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