John E. Sims

19.4k total citations · 6 hit papers
105 papers, 14.6k citations indexed

About

John E. Sims is a scholar working on Immunology, Molecular Biology and Dermatology. According to data from OpenAlex, John E. Sims has authored 105 papers receiving a total of 14.6k indexed citations (citations by other indexed papers that have themselves been cited), including 77 papers in Immunology, 33 papers in Molecular Biology and 13 papers in Dermatology. Recurrent topics in John E. Sims's work include Immune Response and Inflammation (45 papers), Immune Cell Function and Interaction (31 papers) and Dermatology and Skin Diseases (13 papers). John E. Sims is often cited by papers focused on Immune Response and Inflammation (45 papers), Immune Cell Function and Interaction (31 papers) and Dermatology and Skin Diseases (13 papers). John E. Sims collaborates with scholars based in United States, Canada and United Kingdom. John E. Sims's co-authors include Dirk E. Smith, Steven Dower, Blair R. Renshaw, Kirsten E. Garka, Alberto Mantovani, Timothy A. Bird, Francesco Colotta, Jennifer L. Slack, Judith G. Giri and Jennifer E. Towne and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

John E. Sims

105 papers receiving 14.1k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The IL-1 family: regulators of immunity

2010 1.1k citations John E. Sims, Dirk E. Smith profile →
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

2001 1.0k citations Dirk E. Smith, John E. Sims et al. profile →
Interleukin-1 Type II Receptor: A Decoy Target for IL-1 That Is Regulated by IL-4

1993 805 citations Francesco Colotta, Fabio Re et al. Science profile →
cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily

1988 762 citations John E. Sims, David Cosman et al. Science profile →
The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms

1989 568 citations Carl J. March, Steven D. Gimpel et al. profile →
Interleukin 1 signaling occurs exclusively via the type I receptor.

1993 503 citations John E. Sims, Margit Gayle et al. Proceedings of the National Academy of Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
John E. Sims United States	60	10.0k	4.1k	1.9k	1.7k	1.4k	105	14.6k
Katsuko Sudo Japan	44	6.8k 0.7×	4.3k 1.0×	1.4k 0.7×	882 0.5×	1.1k 0.8×	140	13.1k
Björn E. Clausen Germany	57	8.8k 0.9×	3.7k 0.9×	2.4k 1.2×	1.3k 0.7×	1.6k 1.1×	122	14.2k
Jonathon D. Sedgwick Australia	56	10.5k 1.1×	2.0k 0.5×	2.6k 1.3×	909 0.5×	1.5k 1.0×	98	15.0k
Louis Boon Netherlands	72	10.3k 1.0×	3.8k 0.9×	3.1k 1.6×	1.2k 0.7×	2.0k 1.4×	376	17.7k
Jean‐Christophe Renauld Belgium	80	13.8k 1.4×	3.7k 0.9×	4.6k 2.3×	1.5k 0.9×	1.9k 1.3×	243	20.5k
Ueli Gubler United States	39	7.3k 0.7×	5.1k 1.2×	2.4k 1.2×	672 0.4×	1.3k 0.9×	66	14.9k
Jacques Van Snick Belgium	62	9.7k 1.0×	3.1k 0.7×	3.1k 1.6×	555 0.3×	1.7k 1.2×	178	15.8k
Andrew G. Farr United States	56	8.5k 0.9×	2.6k 0.6×	2.0k 1.0×	1.4k 0.8×	629 0.4×	124	13.2k
Haruki Okamura Japan	62	11.0k 1.1×	8.4k 2.0×	2.1k 1.1×	887 0.5×	2.5k 1.8×	238	18.7k
Satish Menon United States	33	8.0k 0.8×	1.9k 0.5×	1.7k 0.9×	1.7k 1.0×	1.3k 0.9×	37	12.3k

Countries citing papers authored by John E. Sims

Since Specialization

Citations

This map shows the geographic impact of John E. Sims's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John E. Sims with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John E. Sims more than expected).

Fields of papers citing papers by John E. Sims

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John E. Sims. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John E. Sims. The network helps show where John E. Sims may publish in the future.

Co-authorship network of co-authors of John E. Sims

This figure shows the co-authorship network connecting the top 25 collaborators of John E. Sims. A scholar is included among the top collaborators of John E. Sims based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John E. Sims. John E. Sims is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Dower, Steven, John E. Sims, Douglas Pat Cerretti, & Timothy A. Bird. (2015). The Interleukin-1 System: Receptors, Ligands and Signals. Chemical immunology/Fortschritte der Allergielehre/Progress in allergy/Chemical immunology and allergy. 51. 33–64. 1 indexed citations

Martin, Unja, John Scholler, Jesse L. Gurgel, et al.. (2009). Externalization of the Leaderless Cytokine IL-1F6 Occurs in Response to Lipopolysaccharide/ATP Activation of Transduced Bone Marrow Macrophages. The Journal of Immunology. 183(6). 4021–4030. 40 indexed citations

Smith, Dirk E., Brian P. Lipsky, Chris B. Russell, et al.. (2009). A Central Nervous System-Restricted Isoform of the Interleukin-1 Receptor Accessory Protein Modulates Neuronal Responses to Interleukin-1. Immunity. 30(6). 817–831. 101 indexed citations

Blumberg, Hal, Huyen Dinh, Esther S. Trueblood, et al.. (2007). Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation. The Journal of Experimental Medicine. 204(11). 2603–2614. 283 indexed citations

Smith, Dirk E., Roberta Hanna, Della Friend, et al.. (2003). The Soluble Form of IL-1 Receptor Accessory Protein Enhances the Ability of Soluble Type II IL-1 Receptor to Inhibit IL-1 Action. Immunity. 18(1). 87–96. 147 indexed citations

Born, Teresa L., Lynda A. Morrison, David J. Esteban, et al.. (2000). A Poxvirus Protein That Binds to and Inactivates IL-18, and Inhibits NK Cell Response. The Journal of Immunology. 164(6). 3246–3254. 144 indexed citations

Born, Teresa L., et al.. (2000). Identification and Characterization of Two Members of a Novel Class of the Interleukin-1 Receptor (IL-1R) Family. Journal of Biological Chemistry. 275(39). 29946–29954. 88 indexed citations

Bessis, Natacha, Alberto Mantovani, Annunciata Vecchi, et al.. (2000). The type II decoy receptor of IL-1 inhibits murine collagen-induced arthritis. European Journal of Immunology. 30(3). 867–875. 69 indexed citations

Torcia, Maria Gabriella, Maria Lucibello, Edouard Vannier, et al.. (1996). Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors.. Cineca Institutional Research Information System (Tor Vergata University). 24(8). 868–74. 36 indexed citations

10.

Re, Fabio, Marina Sironi, Marta Muzio, et al.. (1996). Inhibition of interleukin-1 responsiveness by type II receptor gene transfer: a surface "receptor" with anti-interleukin-1 function.. The Journal of Experimental Medicine. 183(4). 1841–1850. 80 indexed citations

11.

Sims, John E., Judith G. Giri, & Steven Dower. (1994). The Two Interleukin-1 Receptors Play Different Roles in IL-1 Actions. Clinical Immunology and Immunopathology. 72(1). 9–14. 86 indexed citations

12.

Sims, John E., Margit Gayle, Jennifer L. Slack, et al.. (1993). Interleukin 1 signaling occurs exclusively via the type I receptor.. Proceedings of the National Academy of Sciences. 90(13). 6155–6159. 503 indexed citations breakdown →

13.

Sims, John E., et al.. (1993). Comparison of IL-1α effectiveness in activating murine pre-B and T cell lines. Cytokine. 5(5). 416–426. 10 indexed citations

14.

Dower, Steven, et al.. (1990). Structure of IL-1 receptors.. PubMed. 349. 241–9. 2 indexed citations

15.

Fanslow, William C., John E. Sims, Helmut M. Sassenfeld, et al.. (1990). Regulation of Alloreactivity in Vivo by a Soluble Form of the Interleukin-1 Receptor. Science. 248(4956). 739–742. 205 indexed citations

16.

Larsen, A, Benson M. Curtis, Steven D. Gimpel, et al.. (1990). Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains.. The Journal of Experimental Medicine. 172(6). 1559–1570. 179 indexed citations

17.

Dower, Steven & John E. Sims. (1990). Molecular characterisation of cytokine receptors.. PubMed. 49 Suppl 1. 452–9. 6 indexed citations

18.

Dower, Steven, David Cosman, Benson M. Curtis, et al.. (1988). Molecular structure of the interleukin 1 receptor. 7(3). 255. 3 indexed citations

19.

Dressler, David, Dennis E. Hourcade, Kirston Koths, & John E. Sims. (1978). The DNA Replication Cycle of the Isometric Phages. Cold Spring Harbor Monograph Archive. 8. 187–214. 6 indexed citations

20.

Sims, John E., et al.. (1978). Metastatic cloacogenic carcinoma of the anus: sequential responses to adriamycin and cis-dichlorodiammineplatinum(II).. PubMed. 62(1). 91–7. 21 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact