John E. Sims

19.4k citations

105 papers · 14.6k indexed · 6 hit papers · h-index 60

Immunology top 0.05%
- Immune Response and Inflammation 45
- Immune Cell Function and Interaction 31
- IL-33, ST2, and ILC Pathways 13
- T-cell and B-cell Immunology 11
Dermatology top 0.1%
- Dermatology and Skin Diseases 13
Immunology and Allergy top 0.5%
Biological Psychiatry top 2%
Cancer Research top 1%
- NF-κB Signaling Pathways 10
Molecular Biology
- Inflammasome and immune disorders 13
Oncology
- Cytokine Signaling Pathways and Interactions 7

Co-authors: Dirk E. Smith Steven Dower Blair R. Renshaw Kirsten E. Garka Alberto Mantovani Timothy A. Bird Francesco Colotta Jennifer L. Slack
Cited by: Immunology Dermatology Immunology and Allergy
Journals: Journal of Biological Chemistry (16 papers)The Journal of Immunology (11 papers)Cytokine (10 papers)
Partner nations: United States Canada United Kingdom

In The Last Decade

John E. Sims

105 papers receiving 14.1k citations

Hit Papers

6 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2010 Nature reviews. Immunology
2001 Nature
1993 Science
1993 Proceedings of the National Academy of Sciences
1989 Cell
1988 Science

Peers

Countries citing papers authored by John E. Sims

Since Specialization

Citations

This map shows the geographic impact of John E. Sims's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John E. Sims with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John E. Sims more than expected).

Fields of papers citing papers by John E. Sims

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John E. Sims. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John E. Sims. The network helps show where John E. Sims may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John E. Sims, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John E. Sims Line = papers co-authored together John E. Sims links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The Interleukin-1 System: Receptors, Ligands and Signals Chemical immunology/Fortschritte der Allergielehre/Progress in allergy/Chemical immunology and allergy ·Steven Dower,John E. Sims,Douglas Pat Cerretti,Timothy A. Bird	2015	1
2	IL-36 in psoriasis Current Opinion in Pharmacology ·Ji-Yeol Ryu,John E. Sims	2012	115
3	Neuron-Specific Effects of Interleukin-1β Are Mediated by a Novel Isoform of the IL-1 Receptor Accessory Protein Journal of Neuroscience ·Yangyang Huang,Dirk E. Smith,Osvaldo Ibáñez-Sandoval,John E. Sims,Wilma Friedman	2011	136
4	Externalization of the Leaderless Cytokine IL-1F6 Occurs in Response to Lipopolysaccharide/ATP Activation of Transduced Bone Marrow Macrophages The Journal of Immunology ·Unja Martin,John Scholler,Jesse L. Gurgel,Blair R. Renshaw,John E. Sims,Christopher A. Gabel	2009	40
5	A Central Nervous System-Restricted Isoform of the Interleukin-1 Receptor Accessory Protein Modulates Neuronal Responses to Interleukin-1 Immunity ·Dirk E. Smith,Brian P. Lipsky,Chris B. Russell,Randal R. Ketchem,Jacqueline Kirchner,Kelly Hensley,Yangyang Huang,Wilma Friedman,Vincent Boissonneault,Marie-Michèle Plante,Serge Rivest,John E. Sims	2009	101
6	Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation The Journal of Experimental Medicine ·Hal Blumberg,Huyen Dinh,Esther S. Trueblood,James K. Pretorius,David Kugler,Ning Weng,Suzanne T. Kanaly,Jennifer E. Towne,Cynthia R. Willis,Melanie K. Kuechle,John E. Sims,Jacques J. Peschon	2007	283
7	The Soluble Form of IL-1 Receptor Accessory Protein Enhances the Ability of Soluble Type II IL-1 Receptor to Inhibit IL-1 Action Immunity ·Dirk E. Smith,Roberta Hanna,Della Friend,Heather M. Moore,Hongbo Chen,Ann M. Farese,Thomas J. MacVittie,G. Duke Virca,John E. Sims	2003	147
8	IL-1 and IL-18 receptors, and their extended family Current Opinion in Immunology ·John E. Sims	2002	160
9	A Poxvirus Protein That Binds to and Inactivates IL-18, and Inhibits NK Cell Response The Journal of Immunology ·Teresa L. Born,Lynda A. Morrison,David J. Esteban,Tim VandenBos,Ricardo Quintana-Vallejo,Nanhai G. Chen,Melanie K. Spriggs,John E. Sims,R. Mark L. Buller	2000	144
10	Identification of Two Major Sites in the Type I Interleukin-1 Receptor Cytoplasmic Region Responsible for Coupling to Pro-inflammatory Signaling Pathways Journal of Biological Chemistry ·Jennifer L. Slack,Kenneth Schooley,Timothy P. Bonnert,Jennifer L. Mitcham,Eva E. Qwarnström,John E. Sims,Steven Dower	2000	271
11	Binding of Interleukin-18 to the Interleukin-1 Receptor Homologous Receptor IL-1Rrp1 Leads to Activation of Signaling Pathways Similar to Those Used by Interleukin-1 Journal of Interferon & Cytokine Research ·Elisabeth Thomassen,Timothy A. Bird,Blair R. Renshaw,Mary K. Kennedy,John E. Sims	1998	98
12	DIVERGENT EFFECTS OF LPS ON EXPRESSION OF IL-1 RECEPTOR FAMILY MEMBERS IN MONONUCLEAR PHAGOCYTES IN VITRO AND IN VIVO Cytokine ·Simona Saccani,Nadia Polentarutti,Giselle Pentón‐Rol,John E. Sims,Alberto Mantovani	1998	35
13	Modulation of osteoclast-activating factor activity of multiple myeloma bone marrow cells by different interleukin-1 inhibitors. Cineca Institutional Research Information System (Tor Vergata University) ·Maria Gabriella Torcia,Maria Lucibello,Edouard Vannier,S. Fabiani,A Miliani,Gabriele Guidi,W G Li,Steven Dower,John E. Sims,Alan Shaw,Oğuz Peker,Enrico Garaci,F Cozzolino	1996	36
14	Inhibition of interleukin-1 responsiveness by type II receptor gene transfer: a surface "receptor" with anti-interleukin-1 function. The Journal of Experimental Medicine ·Fabio Re,Marina Sironi,Marta Muzio,Claudia Matteucci,Martino Introna,Salvatore J. Orlando,Giselle Pentón‐Rol,Steven Dower,John E. Sims,Francesco Colotta,Alberto Mantovani	1996	80
15	THREE DISTINCT PROMOTERS DIRECT TRANSCRIPTION OF DIFFERENT 5′ UNTRANSLATED REGIONS OF THE HUMAN INTERLEUKIN 1 TYPE I RECEPTOR: A POSSIBLE MECHANISM FOR CONTROL OF TRANSLATION Cytokine ·Ke Ye,Bonnie King,Burton D. Clark,John E. Sims,C A Dinarello	1996	16
16	Structure of IL-1 receptors. PubMed ·Steven Dower,Seyyed Mohammad Hoseini Souraki,John E. Sims	1990	2
17	Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains. The Journal of Experimental Medicine ·A Larsen,Richard J. Saint,Benson M. Curtis,Steven D. Gimpel,John E. Sims,David Cosman,C. Emschermann,João de Araújo Guimarães Neto,Carl J. March,Colin Smith	1990	179
18	Recombinant interleukin 7, pre-B cell growth factor, has costimulatory activity on purified mature T cells. The Journal of Experimental Medicine ·Philip Morrissey,Raymond G. Goodwin,Richard P. Nordan,Dirk Anderson,Kenneth H. Grabstein,David Cosman,John E. Sims,Stephen D. Lupton,Bruce Acres,Steven G. Reed	1989	190
19	Molecular structure of the interleukin 1 receptor Steven Dower,David Cosman,Benson M. Curtis,Byron Gallis,Carl J. March,S Gillis,David L. Urdal,John E. Sims	1988	3
20	The DNA Replication Cycle of the Isometric Phages Cold Spring Harbor Monograph Archive ·David Dressler,Dennis E. Hourcade,Kirston Koths,John E. Sims	1978	6

About John E. Sims

John E. Sims is a scholar working on Immunology, Dermatology and Immunology and Allergy, having authored 105 papers that have together received 14.6k indexed citations. Recurring topics across this work include Immune Response and Inflammation (45 papers), Immune Cell Function and Interaction (31 papers), Dermatology and Skin Diseases (13 papers), IL-33, ST2, and ILC Pathways (13 papers), Inflammasome and immune disorders (13 papers), T-cell and B-cell Immunology (11 papers), NF-κB Signaling Pathways (10 papers) and Cytokine Signaling Pathways and Interactions (7 papers). The work is most often cited by research in Immunology (10.0k citations), Dermatology (1.7k citations) and Immunology and Allergy (886 citations). John E. Sims has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Dirk E. Smith, Steven Dower, Blair R. Renshaw, Kirsten E. Garka, Alberto Mantovani, Timothy A. Bird, Francesco Colotta, Jennifer L. Slack, Judith G. Giri and Jennifer E. Towne. Their work appears in journals such as Journal of Biological Chemistry, The Journal of Immunology, Cytokine, The Journal of Experimental Medicine and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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