David W. Borhani

7.2k citations

48 papers · 5.5k indexed · 2 hit papers · h-index 30

Impact in

Cellular and Molecular Neuroscience top 1%
- Neuropeptides and Animal Physiology
Molecular Biology top 1%
- Receptor Mechanisms and Signaling
- Protein Structure and Dynamics
- Ion channel regulation and function
- Lipid Membrane Structure and Behavior

Papers in

Molecular Biology 39
- Biochemical and Molecular Research 11
- Receptor Mechanisms and Signaling 11
- Protein Structure and Dynamics 6
Cellular and Molecular Neuroscience 8
- Neuropeptides and Animal Physiology 6

Co-authors: David E. Shaw Ron O. Dror Albert C. Pan Daniel H. Arlow Morten Ø. Jensen Paul Maragakis Huafeng Xu Jeffrey A. Engler
Journals: Journal of Biological Chemistry (6 papers)Proceedings of the National Academy of Sciences (6 papers)Biophysical Journal (4 papers)Science (3 papers)Journal of Molecular Biology (3 papers)
Partner nations: United States United Kingdom Australia

In The Last Decade

David W. Borhani

48 papers receiving 5.5k citations

Hit Papers

align trajectories log scale

Pathway and mechanism of drug binding to G-protein-coupled receptors 2011 · 594 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2011 Proceedings of the National Academy of Sciences
2011 Proceedings of the National Academy of Sciences

Peers

Countries citing papers authored by David W. Borhani

Since Specialization

Citations

This map shows the geographic impact of David W. Borhani's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David W. Borhani with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David W. Borhani more than expected).

Fields of papers citing papers by David W. Borhani

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David W. Borhani. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David W. Borhani. The network helps show where David W. Borhani may publish in the future.

Co-authorship network

The 25 scholars most cited alongside David W. Borhani, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David W. Borhani Line = papers co-authored together David W. Borhani links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Structural basis for nucleotide exchange in heterotrimeric G proteins Science ·Ron O. Dror, Thomas J. Mildorf, Daniel Hilger, Aashish Manglik, David W. Borhani, Daniel H. Arlow, Ansgar Philippsen, Nicolas Villanueva, Zhongyu Yang, Michael T. Lerch, Wayne L. Hubbell, Brian K. Kobilka, Roger K. Sunahara, David E. Shaw	2015	216
2	Structural Basis for Modulation of a GPCR by Allosteric Drugs Biophysical Journal ·Ron O. Dror, B. Gimes, Céline Valant, David W. Borhani, James R. Valcourt, Albert C. Pan, Daniel H. Arlow, Meritxell Canals, J. Robert Lane, Raphaël Rahmani, Jonathan B. Baell, Patrick M. Sexton, Arthur Christopoulos, David E. Shaw	2014	1
3	Activation Mechanism of the β2-Adrenergic Receptor Biophysical Journal ·Ron O. Dror, Daniel H. Arlow, Paul Maragakis, Thomas J. Mildorf, Albert C. Pan, Huafeng Xu, David W. Borhani, David E. Shaw	2012	3
4	Pathway and Mechanism of Drug Binding to G-Protein-Coupled Receptors Biophysical Journal ·Ron O. Dror, Albert C. Pan, Daniel H. Arlow, David W. Borhani, Paul Maragakis, Yibing Shan, Huafeng Xu, David E. Shaw	2012	128
5	Pathway and mechanism of drug binding to G-protein-coupled receptors Proceedings of the National Academy of Sciences ·Ron O. Dror, Albert C. Pan, Daniel H. Arlow, David W. Borhani, Paul Maragakis, Yibing Shan, Huafeng Xu, David E. Shaw Hit paper breakdown →	2011	594
6	Principles of conduction and hydrophobic gating in K ⁺ channels Proceedings of the National Academy of Sciences ·Morten Ø. Jensen, David W. Borhani, Kresten Lindorff‐Larsen, Paul Maragakis, Vishwanath Jogini, Michael P. Eastwood, Ron O. Dror, David E. Shaw	2010	266
7	Identification Of Two Distinct Inactive Conformations Of The Beta-2 Adrenergic Receptor Reconciles Structural And Biochemical Observations Biophysical Journal ·Ron O. Dror, Daniel H. Arlow, David W. Borhani, W. Li, David E. Shaw	2009	17
8	Rational mutagenesis to support structure-based drug design: MAPKAP kinase 2 as a case study BMC Structural Biology ·M.A. Argiriadi, Herbert Fahey, David Banach, D.J. Marcotte, Sirisha Mintnala, 土井勝幸, Kabwata Chisala, Christopher M. Harris, Na-yeon Kim, Jennifer Hardman, Haitham Abdelrhman Naser, Zaile Zhuang, Anna G. Sepúlveda-Salinas, Baofu Ni, John A. Mankovich, David W. Borhani, Robert V. Talanian, Ramkrishna Sadhukhan	2009	9
9	A scalable parallel framework for analyzing terascale molecular dynamics simulation trajectories IEEE International Conference on High Performance Computing, Data, and Analytics ·Tiankai Tu, Charles A. Rendleman, David W. Borhani, Ron O. Dror, Justin Gullingsrud, Morten Ø. Jensen, John L. Klepeis, Paul Maragakis, Patrick J. O. Miller, Kate A. Stafford, David E. Shaw	2008	36
10	Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection Bioorganic & Medicinal Chemistry Letters ·Andrew Burchat, David W. Borhani, David J. Calderwood, Gavin C. Hirst, Biqin Li, Robert F. Stachlewitz	2005	63
11	Polymerization of C-terminally truncated Mycobacterium tuberculosis FtsZ is unlikely to be physiologically relevant Microbiology ·David W. Borhani	2004	2
12	A-420983: a potent, orally active inhibitor of lck with efficacy in a model of transplant rejection Bioorganic & Medicinal Chemistry Letters ·David W. Borhani, David J. Calderwood, Michael Friedman, Gavin C. Hirst, Biqin Li, Adelaine Kwun-Wai Leung, Amy Onken, S Ratnofsky, Kurt Ritter, Wendy Waegell	2004	30
13	Structure of Mycobacterium tuberculosis FtsZ Reveals Unexpected, G Protein-like Conformational Switches Journal of Molecular Biology ·Adelaine Kwun-Wai Leung, E. Lucile White, Larry J. Ross, Robert C. Reynolds, Joseph A. DeVito, David W. Borhani	2004	105
14	Atomic Structures of Human Dihydrofolate Reductase Complexed with NADPH and Two Lipophilic Antifolates at 1.09Å and 1.05Å Resolution Journal of Molecular Biology ·Anthony E. Klon, A. Héroux, Larry J. Ross, Vibha Pathak, KARAYALÇIN Yaşar, James R. Piper, David W. Borhani	2002	61
15	Structural models of human apolipoprotein A-I: a critical analysis and review Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ·Christie G. Brouillette, G.M. Anantharamaiah, Jeffrey A. Engler, David W. Borhani	2001	200
16	Crystallization of theMycobacterium tuberculosiscell-division protein FtsZ Acta Crystallographica Section D Biological Crystallography ·Adelaine Kwun-Wai Leung, E. Lucile White, Larry J. Ross, David W. Borhani	2000	11
17	Substrate Deformation in a Hypoxanthine-Guanine Phosphoribosyltransferase Ternary Complex Structure ·A. Héroux, E. Lucile White, Larry J. Ross, Gustav Tammann Unter Standiger Mitarbeit, David W. Borhani	2000	64
18	Michellamine Alkaloids Inhibit Protein Kinase C Archives of Biochemistry and Biophysics ·E. Lucile White, Wan‐Ru Chao, Larry J. Ross, David W. Borhani, Peter D. Hobbs, Upender Velaparthi, Marcia I. Dawson	1999	17
19	Kinetic Alteration of Human Aldose Reductase by Mutagenesis of Cysteine Residues Advances in experimental medicine and biology ·J. Mark Petrash, Theresa M. Harter, H RAKOWSKI, David W. Borhani	1993	4
20	THE CRYSTAL STRUCTURE OF THE ALDOSE REDUCTASE NADPH BINARY COMPLEX PubMed ·David W. Borhani, Theresa M. Harter, J. Mark Petrash	1992	91

About David W. Borhani

David W. Borhani is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Cell Biology, Spectroscopy and Infectious Diseases, having authored 48 papers that have together received 5.5k indexed citations. Recurring topics across this work include Biochemical and Molecular Research (11 papers), Receptor Mechanisms and Signaling (11 papers), Mass Spectrometry Techniques and Applications (7 papers), Enzyme Structure and Function (7 papers), Protein Structure and Dynamics (6 papers), Neuropeptides and Animal Physiology (6 papers), HIV/AIDS drug development and treatment (6 papers) and Aldose Reductase and Taurine (5 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (1.2k citations), Molecular Biology (4.2k citations), Computational Theory and Mathematics (634 citations), Spectroscopy (486 citations) and Cell Biology (467 citations). David W. Borhani has collaborated with scholars based in United States, United Kingdom and Australia. Frequent co-authors include David E. Shaw, Ron O. Dror, Albert C. Pan, Daniel H. Arlow, Morten Ø. Jensen, Paul Maragakis, Huafeng Xu, Jeffrey A. Engler, Christie G. Brouillette and Vishwanath Jogini. Their work appears in journals such as Journal of Biological Chemistry, Proceedings of the National Academy of Sciences, Biophysical Journal, Science and Journal of Molecular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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