Aashish Manglik

18.5k total citations · 14 hit papers
57 papers, 10.8k citations indexed

About

Aashish Manglik is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Aashish Manglik has authored 57 papers receiving a total of 10.8k indexed citations (citations by other indexed papers that have themselves been cited), including 50 papers in Molecular Biology, 36 papers in Cellular and Molecular Neuroscience and 8 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Aashish Manglik's work include Receptor Mechanisms and Signaling (39 papers), Neuropeptides and Animal Physiology (32 papers) and Monoclonal and Polyclonal Antibodies Research (8 papers). Aashish Manglik is often cited by papers focused on Receptor Mechanisms and Signaling (39 papers), Neuropeptides and Animal Physiology (32 papers) and Monoclonal and Polyclonal Antibodies Research (8 papers). Aashish Manglik collaborates with scholars based in United States, Belgium and Canada. Aashish Manglik's co-authors include Brian K. Kobilka, Andrew C. Kruse, William I. Weis, Tong Sun Kobilka, Foon Sun Thian, Sébastien Granier, Jan Steyaert, Ron O. Dror, Daniel Hilger and Aaron M. Ring and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Aashish Manglik

54 papers receiving 10.7k citations

Hit Papers

Crystal structure of the µ-opioid receptor bound to a mor... 2012 2026 2016 2021 2012 2013 2015 2016 2013 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
    2012 1.1k citations Aashish Manglik, Andrew C. Kruse et al. Nature profile →
  2. Activation and allosteric modulation of a muscarinic acetylcholine receptor
    2013 712 citations Andrew C. Kruse, Aaron M. Ring et al. Nature profile →
  3. Structural insights into µ-opioid receptor activation
    2015 700 citations Weijiao Huang, Aashish Manglik et al. Nature profile →
  4. Structure-based discovery of opioid analgesics with reduced side effects
    2016 697 citations Aashish Manglik, Henry J. Lin et al. Nature profile →
  5. The Dynamic Process of β2-Adrenergic Receptor Activation
    2013 646 citations Ron O. Dror, Thomas J. Mildorf et al. Cell profile →
  6. Structure of the δ-opioid receptor bound to naltrindole
    2012 546 citations Sébastien Granier, Aashish Manglik et al. Nature profile →
  7. Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling
    2015 521 citations Aashish Manglik, Tae Hun Kim et al. Cell profile →
  8. Structure of the µ-opioid receptor–Gi protein complex
    2018 495 citations Antoine Koehl, Daniel Hilger et al. Nature profile →
  9. Adrenaline-activated structure of β2-adrenoceptor stabilized by an engineered nanobody
    2013 408 citations Aaron M. Ring, Aashish Manglik et al. Nature profile →
  10. Crystal structure of the human σ1 receptor
    2016 384 citations Antoine Koehl, Aashish Manglik et al. Nature profile →
  11. Yeast surface display platform for rapid discovery of conformationally selective nanobodies
    2018 348 citations Daniel Hilger, Søren G. F. Rasmussen et al. profile →
  12. Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms
    2020 242 citations Christian B. Billesbølle, Ron O. Dror et al. Nature profile →
  13. Protein design and variant prediction using autoregressive generative models
    2021 195 citations Aashish Manglik, Andrew C. Kruse et al. Nature Communications profile →
  14. Structural basis of odorant recognition by a human odorant receptor
    2023 103 citations Christian B. Billesbølle, Claire A. de March et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Aashish Manglik United States 38 9.4k 5.6k 1.8k 945 791 57 10.8k
Hee‐Jung Choi South Korea 30 9.2k 1.0× 4.2k 0.8× 1.5k 0.8× 944 1.0× 659 0.8× 96 10.4k
Foon Sun Thian United States 12 11.7k 1.2× 7.0k 1.3× 2.1k 1.2× 1.3k 1.4× 978 1.2× 13 12.5k
Andrew C. Kruse United States 51 11.9k 1.3× 5.5k 1.0× 2.2k 1.2× 1.2k 1.3× 786 1.0× 101 14.3k
Christopher G. Tate United Kingdom 59 11.7k 1.2× 5.7k 1.0× 2.2k 1.2× 991 1.0× 1.3k 1.6× 130 13.4k
Els Pardon Belgium 48 9.8k 1.0× 3.7k 0.7× 2.7k 1.5× 683 0.7× 612 0.8× 137 12.0k
Gye Won Han United States 43 9.0k 1.0× 4.6k 0.8× 1.5k 0.8× 1.1k 1.2× 498 0.6× 90 10.7k
Michael A. Hanson United States 37 9.6k 1.0× 4.8k 0.9× 1.5k 0.9× 1.1k 1.2× 680 0.9× 58 11.1k
David E. Gloriam Denmark 38 6.9k 0.7× 3.7k 0.7× 1.0k 0.6× 1.2k 1.3× 592 0.7× 107 8.6k
Fiona H. Marshall United Kingdom 53 7.0k 0.7× 4.7k 0.8× 1.2k 0.7× 892 0.9× 323 0.4× 100 9.3k
Peter Gmeiner Germany 48 7.7k 0.8× 4.5k 0.8× 1.2k 0.6× 954 1.0× 540 0.7× 341 10.5k

Countries citing papers authored by Aashish Manglik

Since Specialization
Citations

This map shows the geographic impact of Aashish Manglik's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Aashish Manglik with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Aashish Manglik more than expected).

Fields of papers citing papers by Aashish Manglik

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Aashish Manglik. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Aashish Manglik. The network helps show where Aashish Manglik may publish in the future.

Co-authorship network of co-authors of Aashish Manglik

This figure shows the co-authorship network connecting the top 25 collaborators of Aashish Manglik. A scholar is included among the top collaborators of Aashish Manglik based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Aashish Manglik. Aashish Manglik is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Hoppe, Nick, Xi‐Ping Huang, Christian B. Billesbølle, et al.. (2025). Molecular basis of proton sensing by G protein-coupled receptors. Cell. 188(3). 671–687.e20. 14 indexed citations
2.
Billesbølle, Christian B., Tuan Dinh, Erick Lu, et al.. (2025). Phenotypic pleiotropy of missense variants in human B cell confinement receptor P2RY8. Cell Genomics. 5(11). 100981–100981.
3.
Yu, Jun, Charlotte Martin, Antoine Koehl, et al.. (2024). Structural basis of μ-opioid receptor targeting by a nanobody antagonist. Nature Communications. 15(1). 8687–8687. 12 indexed citations
4.
March, Claire A. de, Ning Ma, Christian B. Billesbølle, et al.. (2024). Engineered odorant receptors illuminate the basis of odour discrimination. Nature. 635(8038). 499–508. 9 indexed citations
5.
Manglik, Aashish, et al.. (2023). Rare antibody phage isolation and discrimination (RAPID) biopanning enables identification of high-affinity antibodies against challenging targets. Communications Biology. 6(1). 1036–1036. 8 indexed citations
6.
Billesbølle, Christian B., Claire A. de March, Wijnand J. C. van der Velden, et al.. (2023). Structural basis of odorant recognition by a human odorant receptor. Nature. 615(7953). 742–749. 103 indexed citations breakdown →
7.
Hedeen, Danielle, Dana Klatt Shaw, Ishan Deshpande, et al.. (2021). Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits. PLoS Biology. 19(4). e3001191–e3001191. 39 indexed citations
8.
Zhang, Yunxiao, Wan-Jin Lu, David Bulkley, et al.. (2020). Hedgehog pathway activation through nanobody-mediated conformational blockade of the Patched sterol conduit. Proceedings of the National Academy of Sciences. 117(46). 28838–28846. 25 indexed citations
9.
Appa, Ayesha, Saki Takahashi, Isabel Rodríguez-Barraquer, et al.. (2020). Universal Polymerase Chain Reaction and Antibody Testing Demonstrate Little to No Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 in a Rural Community. Open Forum Infectious Diseases. 8(1). ofaa531–ofaa531. 6 indexed citations
10.
Manglik, Aashish. (2019). Molecular Basis of Opioid Action: From Structures to New Leads. Biological Psychiatry. 87(1). 6–14. 34 indexed citations
11.
Manglik, Aashish, Henry J. Lin, Dipendra K. Aryal, et al.. (2016). Structure-based discovery of opioid analgesics with reduced side effects. Nature. 537(7619). 185–190. 697 indexed citations breakdown →
12.
Dror, Ron O., Thomas J. Mildorf, Daniel Hilger, et al.. (2015). Structural basis for nucleotide exchange in heterotrimeric G proteins. Science. 348(6241). 1361–1365. 216 indexed citations
13.
Huang, Weijiao, Aashish Manglik, AJ Venkatakrishnan, et al.. (2015). Structural insights into µ-opioid receptor activation. Nature. 524(7565). 315–321. 700 indexed citations breakdown →
14.
Manglik, Aashish, Tae Hun Kim, Matthieu Masureel, et al.. (2015). Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling. Cell. 161(5). 1101–1111. 521 indexed citations breakdown →
15.
Sounier, Rémy, Jan Steyaert, Toon Laeremans, et al.. (2015). Propagation of conformational changes during μ-opioid receptor activation. Nature. 524(7565). 375–378. 202 indexed citations
16.
Weichert, Dietmar, Andrew C. Kruse, Aashish Manglik, et al.. (2014). Covalent agonists for studying G protein-coupled receptor activation. Proceedings of the National Academy of Sciences. 111(29). 10744–10748. 74 indexed citations
17.
Kruse, Andrew C., Aashish Manglik, Brian K. Kobilka, & William I. Weis. (2013). Applications of molecular replacement to G protein-coupled receptors. Acta Crystallographica Section D Biological Crystallography. 69(11). 2287–2292. 4 indexed citations
18.
Kruse, Andrew C., Aaron M. Ring, Aashish Manglik, et al.. (2013). Activation and allosteric modulation of a muscarinic acetylcholine receptor. Nature. 504(7478). 101–106. 712 indexed citations breakdown →
19.
Chae, Pil Seok, Søren G. F. Rasmussen, Rohini R. Rana, et al.. (2012). A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins. Chemistry - A European Journal. 18(31). 9485–9490. 126 indexed citations
20.
Manglik, Aashish, Andrew C. Kruse, Tong Sun Kobilka, et al.. (2012). Crystal structure of the µ-opioid receptor bound to a morphinan antagonist. Nature. 485(7398). 321–326. 1088 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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