Gavin C. Hirst

1.5k total citations
23 papers, 731 citations indexed

About

Gavin C. Hirst is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, Gavin C. Hirst has authored 23 papers receiving a total of 731 indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Molecular Biology, 7 papers in Organic Chemistry and 6 papers in Oncology. Recurrent topics in Gavin C. Hirst's work include Immune Cell Function and Interaction (4 papers), Cytokine Signaling Pathways and Interactions (4 papers) and Signaling Pathways in Disease (3 papers). Gavin C. Hirst is often cited by papers focused on Immune Cell Function and Interaction (4 papers), Cytokine Signaling Pathways and Interactions (4 papers) and Signaling Pathways in Disease (3 papers). Gavin C. Hirst collaborates with scholars based in United States and United Kingdom. Gavin C. Hirst's co-authors include Larry E. Overman, Theodore Johnson, David J. Calderwood, Andrew Burchat, Biqin Li, Robert F. Stachlewitz, S Ratnofsky, David W. Borhani, Paul Rafferty and Kennedy L. Queen and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Medicinal Chemistry and Journal of Pharmacology and Experimental Therapeutics.

In The Last Decade

Gavin C. Hirst

23 papers receiving 686 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Gavin C. Hirst United States 15 315 298 166 95 85 23 731
Rosanna Tedesco United States 13 345 1.1× 368 1.2× 107 0.6× 46 0.5× 57 0.7× 15 1.1k
Xihan Wu China 16 781 2.5× 275 0.9× 249 1.5× 81 0.9× 63 0.7× 35 1.1k
Jack A. Kauffman United States 16 416 1.3× 365 1.2× 81 0.5× 49 0.5× 99 1.2× 30 853
Clive McCarthy United Kingdom 16 255 0.8× 271 0.9× 68 0.4× 50 0.5× 47 0.6× 29 673
Roland Feifel Switzerland 21 769 2.4× 338 1.1× 164 1.0× 206 2.2× 155 1.8× 36 1.3k
Kathleen M. Gillooly United States 14 263 0.8× 145 0.5× 166 1.0× 41 0.4× 263 3.1× 17 778
Melvin J. Yu United States 17 402 1.3× 326 1.1× 422 2.5× 61 0.6× 78 0.9× 30 1.1k
Jeffrey O. Saunders United States 9 363 1.2× 192 0.6× 212 1.3× 35 0.4× 32 0.4× 12 877
GR Pettit United States 10 509 1.6× 170 0.6× 206 1.2× 28 0.3× 82 1.0× 10 861
James P. Rizzi United States 15 894 2.8× 249 0.8× 128 0.8× 158 1.7× 66 0.8× 20 1.3k

Countries citing papers authored by Gavin C. Hirst

Since Specialization
Citations

This map shows the geographic impact of Gavin C. Hirst's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gavin C. Hirst with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gavin C. Hirst more than expected).

Fields of papers citing papers by Gavin C. Hirst

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gavin C. Hirst. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gavin C. Hirst. The network helps show where Gavin C. Hirst may publish in the future.

Co-authorship network of co-authors of Gavin C. Hirst

This figure shows the co-authorship network connecting the top 25 collaborators of Gavin C. Hirst. A scholar is included among the top collaborators of Gavin C. Hirst based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Gavin C. Hirst. Gavin C. Hirst is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Bembenek, Scott D., Gavin C. Hirst, & Taraneh Mirzadegan. (2018). Determination of a Focused Mini Kinase Panel for Early Identification of Selective Kinase Inhibitors. Journal of Chemical Information and Modeling. 58(7). 1434–1440. 11 indexed citations
2.
Antonysamy, Stephen, Gavin C. Hirst, Paul A. Sprengeler, et al.. (2008). Fragment-based discovery of JAK-2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 19(1). 279–282. 64 indexed citations
3.
Donnelly‐Roberts, Diana L., Michael Friedman, Jonathan S. George, et al.. (2008). Synthesis and activity of N-cyanoguanidine-piperazine P2X7 antagonists. Bioorganic & Medicinal Chemistry Letters. 18(14). 3848–3851. 9 indexed citations
4.
Burchat, Andrew, David J. Calderwood, Peter Hrnčiar, et al.. (2006). Discovery of thienopyridines as Src-family selective Lck inhibitors. Bioorganic & Medicinal Chemistry Letters. 17(5). 1167–1171. 17 indexed citations
5.
Burchat, Andrew, David W. Borhani, David J. Calderwood, et al.. (2005). Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection. Bioorganic & Medicinal Chemistry Letters. 16(1). 118–122. 63 indexed citations
6.
Stachlewitz, Robert F., Brian R. Bettencourt, Annette Schwartz, et al.. (2005). A-770041, a Novel and Selective Small-Molecule Inhibitor of Lck, Prevents Heart Allograft Rejection. Journal of Pharmacology and Experimental Therapeutics. 315(1). 36–41. 45 indexed citations
7.
Wilkins, Julie A., James L. Kofron, Yong Jia, et al.. (2004). Utilization of Microarrayed Compound Screening (μARCS) to Identify Inhibitors of p56lck Tyrosine Kinase. SLAS DISCOVERY. 9(1). 12–21. 5 indexed citations
8.
Borhani, David W., David J. Calderwood, Michael Friedman, et al.. (2004). A-420983: a potent, orally active inhibitor of lck with efficacy in a model of transplant rejection. Bioorganic & Medicinal Chemistry Letters. 14(10). 2613–2616. 30 indexed citations
9.
McRae, Bradford L., et al.. (2004). Suppression of CD4+ T cell activation by a novel inhibitor of Src family kinases. International Immunopharmacology. 5(4). 667–677. 9 indexed citations
10.
Burchat, Andrew, David J. Calderwood, Michael Friedman, et al.. (2002). Pyrazolo[3,4‐d]pyrimidines Containing an Extended 3‐Substituent as Potent Inhibitors of Lck — A Selectivity Insight.. ChemInform. 33(39). 158–158. 1 indexed citations
11.
Waegell, Wendy, Michael W. Leach, S Ratnofsky, et al.. (2002). A420983, a novel, small molecule inhibitor of LCK prevents allograft rejection. Transplantation Proceedings. 34(5). 1411–1417. 18 indexed citations
12.
Burchat, Andrew, David J. Calderwood, Michael Friedman, et al.. (2002). Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck — a selectivity insight. Bioorganic & Medicinal Chemistry Letters. 12(12). 1687–1690. 48 indexed citations
13.
Kamens, Joanne, S Ratnofsky, & Gavin C. Hirst. (2001). Lck inhibitors as a therapeutic approach to autoimmune disease and transplant rejection.. PubMed. 2(9). 1213–9. 16 indexed citations
14.
Burchat, Andrew, et al.. (2000). Pyrrolo[2,3-d]pyrimidines Containing an Extended 5-Substituent as Potent and Selective Inhibitors of lck II. Bioorganic & Medicinal Chemistry Letters. 10(19). 2171–2174. 40 indexed citations
15.
Henke, Brad R., Christopher Aquino, Larry S. Birkemo, et al.. (1997). Optimization of 3-(1H-Indazol-3-ylmethyl)-1,5-benzodiazepines as Potent, Orally Active CCK-A Agonists. Journal of Medicinal Chemistry. 40(17). 2706–2725. 63 indexed citations
16.
Hirst, Gavin C., et al.. (1997). Conversion of acyclic nonpeptide CCK antagonists into CCK agonists. Bioorganic & Medicinal Chemistry Letters. 7(5). 511–514. 3 indexed citations
17.
Hirst, Gavin C., Christopher Aquino, Dallas K. Croom, et al.. (1996). Discovery of 1,5-Benzodiazepines with Peripheral Cholecystokinin (CCK-A) Receptor Agonist Activity (II):  Optimization of the C3 Amino Substituent. Journal of Medicinal Chemistry. 39(26). 5236–5245. 31 indexed citations
18.
Hirst, Gavin C., Theodore Johnson, & Larry E. Overman. (1993). First total synthesis of Lycopodium alkaloids of the magellanane group. Enantioselective total syntheses of (-)-magellanine and (+)-magellaninone. Journal of the American Chemical Society. 115(7). 2992–2993. 106 indexed citations
19.
Middlemiss, David, Steve P. Watson, Barry C. Ross, et al.. (1993). Benzofuran based angiotensi II antagonists related to GR117289: Part II; amino acid amides. Bioorganic & Medicinal Chemistry Letters. 3(10). 2043–2046. 3 indexed citations
20.
Buss, Antony D., Gavin C. Hirst, & Philip J. Parsons. (1987). Regiochemical control of the Diels–Alder reactions with β-phenylsulphonylacrylate esters. Journal of the Chemical Society Chemical Communications. 1836–1837. 16 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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