David Serreze

13.0k citations

184 papers · 10.4k indexed · 1 hit paper · h-index 54

Impact in

Immunology top 0.2%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Immune Response and Inflammation
Genetics top 0.05%
- Diabetes and associated disorders

Papers in

Genetics 150
- Diabetes and associated disorders 149
Immunology 109
- Immune Cell Function and Interaction 83
- T-cell and B-cell Immunology 67
- Immune Response and Inflammation 5

Co-authors: Edward H. Leiter Harold D. Chapman Teresa P. DiLorenzo Michal Procházka Roland Tisch H.D. Chapman Leonard D. Shultz Derry C. Roopenian
Journals: The Journal of Immunology (50 papers)Diabetes (42 papers)Proceedings of the National Academy of Sciences (9 papers)The Journal of Experimental Medicine (6 papers)Immunogenetics (4 papers)
Partner nations: United States Canada United Kingdom

In The Last Decade

David Serreze

181 papers receiving 10.3k citations

Hit Papers

align trajectories log scale

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice. 1996 · 502 citations

Peers

Countries citing papers authored by David Serreze

Since Specialization

Citations

This map shows the geographic impact of David Serreze's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David Serreze with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David Serreze more than expected).

Fields of papers citing papers by David Serreze

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David Serreze. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David Serreze. The network helps show where David Serreze may publish in the future.

Co-authors

The 25 scholars most cited alongside David Serreze, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David Serreze Line = papers co-authored together David Serreze links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response Cell Reports ·Daniel A. Skelly, M. Casey, Mingshan Cheng, Mayuko Furuta, 典央斉藤, Thomas A. Stoklasek, 鬼頭慎司, Simon Vajda, Olivier Poirion, Jigang Zhang, Jessica Grassmann, Diane Luo, William F. Flynn, Elise T. Courtois, Chih-Hao Chang, David Serreze, Francesca Menghi, Laura G. Reinholdt, Edison T. Liu	2025	2
2	Murine MHC-Deficient Nonobese Diabetic Mice Carrying Human HLA-DQ8 Develop Severe Myocarditis and Myositis in Response to Anti–PD-1 Immune Checkpoint Inhibitor Cancer Therapy The Journal of Immunology ·Jeremy J. Racine, John F. Bachman, Jigang Zhang, Glenn Y. Terashita, Paula Virgínia Gomes, Qiao Feng-lon, S. Hyman, I Putu Raka Kamista Putra, A. N. Abbott, Elvira Forte, Peter P. Rainer, Nadia Rosenthal, Susanne Sattler, David Serreze	2024	7
3	Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes Cell Host & Microbe ·هديل ريحان, Leonid Yurkovetskiy, Andrey Kuznetsov, Derek Reiman, Camilla Hartmann Friis Hansen, Razan Awad, Jean Lee, Karin Ahlman, Shiva Dahal‐Koirala, Dionysios A. Antonopoulos, Gary M. Dunny, Ludvig M. Sollid, David Serreze, Aly A. Khan, Alexander V. Chervonsky	2023	10
4	T Cells from NOD-PerIg Mice Target Both Pancreatic and Neuronal Tissue The Journal of Immunology ·Jeremy J. Racine, Harold D. Chapman, Rosalinda Doty, M.A. Ribeiro, Kelly Chien, Abigail L. D. Tadenev, Laura Anderson, Eman Saleh Akeel, 洋輔浅野, Janine M. Wotton, Zoë Bichler, Jacqueline K. White, Rachel Ettinger, Robert W. Burgess, David Serreze	2020	4
5	HLA-B39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression The Journal of Immunology* ·Pengwei Li, Riyasat Ali, Jeremy J. Racine, Harold D. Chapman, David Serreze, Teresa P. DiLorenzo	2018	19
6	Genetic Analysis of Substrain Divergence in Non-Obese Diabetic (NOD) Mice G3 Genes Genomes Genetics ·Petr Šimeček, Gary A. Churchill, Hyuna Yang, Lucy B. Rowe, L. Herberg, David Serreze, Edward H. Leiter	2015	19
7	Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 ⁺ T cells in NOD mice Proceedings of the National Academy of Sciences ·Arunika Mukhopadhaya, Tadashi Hanafusa, Irene Jarchum, E. D. Prentice, Yoshiko Iwai, David Serreze, Ralph M. Steinman, Kristin V. Tarbell, Teresa P. DiLorenzo	2008	115
8	Targeted Disruption of CD38 Accelerates Autoimmune Diabetes in NOD/Lt Mice by Enhancing Autoimmunity in an ADP-Ribosyltransferase 2-Dependent Fashion The Journal of Immunology ·Jing Chen, Yi‐Guang Chen, Peter C. Reifsnyder, William Schott, Chul‐Ho Lee, Melissa Osborne, Felix Scheuplein, Friedrich Haag, Friedrich Koch‐Nolte, David Serreze, Edward H. Leiter	2006	53
9	Genes within the Idd5 and Idd9/11 Diabetes Susceptibility Loci Affect the Pathogenic Activity of B Cells in Nonobese Diabetic Mice The Journal of Immunology ·Pablo A. Silveira, Harold D. Chapman, Jessica Stolp, Ellis Johnson, 满林香, Kara Hunter, Linda S. Wicker, David Serreze	2006	25
10	CD38 Is Required for the Peripheral Survival of Immunotolerogenic CD4+ Invariant NK T Cells in Nonobese Diabetic Mice The Journal of Immunology ·E. D. Prentice, Jing Chen, Melissa Osborne, Harold D. Chapman, Gurdyal S. Besra, Steven A. Porcelli, Edward H. Leiter, S. Brian Wilson, David Serreze	2006	24
11	HLA-A0201-Restricted T Cells from Humanized NOD Mice Recognize Autoantigens of Potential Clinical Relevance to Type 1 Diabetes The Journal of Immunology* ·Toshiyuki Takaki, Michele P. Marron, Clayton E. Mathews, M.V. Kruchinina, Rita Bottino, Massimo Trucco, Teresa P. DiLorenzo, David Serreze	2006	100
12	Rapid Destruction of Encapsulated Islet Xenografts by NOD Mice is CD4-Dependent and Facilitated by B-cells: Innate Immunity and Autoimmunity Do Not Play Significant Roles Transplantation ·孝二大野, Hua Yang, David Serreze, Rebecca Macintosh, Weiming Yu, James R. Wright	2005	11
13	ACCELERATED TYPE 1 DIABETES IN CD38-DEFICIENT NOD MICE THROUGH A FURTHER LOSS OF DISEASE PROTECTIVE NKT CELLS AND MATURE DENDRITIC CELLS Endocrine Journal ·Yi‐Guang Chen, Jing Chen, Martin Bergerhausen, Edward H. Leiter, David Serreze	2005	1
14	Activated NKT Cells Inhibit Autoimmune Diabetes through Tolerogenic Recruitment of Dendritic Cells to Pancreatic Lymph Nodes The Journal of Immunology ·E. D. Prentice, Verônica Ribeiro Barros, Thomas M. Holl, Harold D. Chapman, Gurdyal S. Besra, Steven A. Porcelli, Daniel J. Shaffer, Derry C. Roopenian, S. Brian Wilson, David Serreze	2005	117
15	Diabetes Acceleration or Prevention by a Coxsackievirus B4 Infection: Critical Requirements for both Interleukin-4 and Gamma Interferon Journal of Virology ·David Serreze, Clive Wasserfall, Eric Ottendorfer, Michael S. Stalvey, Sonali Mishra, Charles J. Gauntt, Nikitenko Ng, James B. Flanagan, Martha Campbell‐Thompson, Tamir M. Ellis, Mark A. Atkinson	2004	56
16	Identification of the β cell antigen targeted by a prevalent population of pathogenic CD8 ⁺ T cells in autoimmune diabetes Proceedings of the National Academy of Sciences ·Scott M. Lieberman, Anne M. Evans, Bingye Han, Toshiyuki Takaki, Pandit Ghanshyamji Suman Pundlik Thorat, Jennifer Caldwell, David Serreze, Jeffrey Shabanowitz, Donald F. Hunt, Stanley G. Nathenson, Pere Santamaría, Teresa P. DiLorenzo	2003	320
17	Paralytic Autoimmune Myositis Develops in Nonobese Diabetic Mice Made Th1 Cytokine-Deficient by Expression of an IFN-γ Receptor β-Chain Transgene The Journal of Immunology ·David Serreze, Sonali Mishra, A Adesh Sai, Harold D. Chapman, Vera Varga, Roderick T. Bronson, Paul B. Rothman, Gregory A. Cox	2003	7
18	Th1 to Th2 Cytokine Shifts in Nonobese Diabetic Mice: Sometimes an Outcome, Rather Than the Cause, of Diabetes Resistance Elicited by Immunostimulation The Journal of Immunology ·David Serreze, Harold D. Chapman, A Adesh Sai, E. A. Johnson, Wilma L. Suarez‐Pinzon, Alex Rabinovitch	2001	148
19	Inhibition of Autoimmune Diabetes in Nonobese Diabetic Mice by Transgenic Restoration of H2-E MHC Class II Expression: Additive, But Unequal, Involvement of Multiple APC Subtypes The Journal of Immunology ·E. A. Johnson, Pablo A. Silveira, Harold D. Chapman, Edward H. Leiter, David Serreze	2001	34
20	A Glutamic Acid Decarboxylase 65-Specific Th2 Cell Clone Immunoregulates Autoimmune Diabetes in Nonobese Diabetic Mice The Journal of Immunology ·Roland Tisch, Bo Wang, Mark A. Atkinson, David Serreze, Randall H. Friedline	2001	45

About David Serreze

David Serreze is a scholar working on Genetics, Immunology, Endocrinology, Diabetes and Metabolism, Surgery and Physiology, having authored 184 papers that have together received 10.4k indexed citations. Recurring topics across this work include Diabetes and associated disorders (149 papers), Pancreatic function and diabetes (86 papers), Immune Cell Function and Interaction (83 papers), T-cell and B-cell Immunology (67 papers), Diabetes Management and Research (36 papers), Metabolism, Diabetes, and Cancer (7 papers), Immune Response and Inflammation (5 papers) and Monoclonal and Polyclonal Antibodies Research (4 papers). The work is most often cited by research in Immunology (5.7k citations), Genetics (6.7k citations), Endocrinology, Diabetes and Metabolism (2.2k citations), Surgery (3.8k citations) and Physiology (177 citations). David Serreze has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Edward H. Leiter, Harold D. Chapman, Teresa P. DiLorenzo, Michal Procházka, Roland Tisch, H.D. Chapman, Leonard D. Shultz, Derry C. Roopenian, Sara Fleming and Yi‐Guang Chen. Their work appears in journals such as The Journal of Immunology, Diabetes, Proceedings of the National Academy of Sciences, The Journal of Experimental Medicine and Immunogenetics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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